| 1 | DKCD, ENOSF1, TYMS
|
| Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita
|
| Tummala H, Walne A, Buccafusca R, Alnajar J, Szabo A, Robinson P, McConkie-Rosell A, Wilson M, Crowley S, Kinsler V, Ewins AM, Madapura PM, Patel M, Pontikos N, Codd V, Vulliamy T, Dokal I.
|
| Am J Hum Genet. Aug 4;109(8):1472-1483. doi: 10.1016/j.ajhg.2022.06.014. 2022
|
| 2 | TYMS
|
| Thymidylate synthase is essential for efficient HIV-1 replication in macrophages.
|
| Desrosiers V, Barat C, Breton Y, Ouellet M, Tremblay MJ.
|
| Virology. Sep;561:47-57. doi: 10.1016/j.virol.2021.05.002. Epub 2021 Jun 14. 2021
|
| 3 | TYMS
|
| Identification of TYMS as a promoting factor of retroperitoneal liposarcoma progression: Bioinformatics analysis and biological evidence
|
| Zhang S, Yan L, Cui C, Wang Z, Wu J, Zhao M, Dong B, Guan X, Tian X, Hao C.
|
| Oncol Rep. Aug;44(2):565-576. doi: 10.3892/or.2020.7635. Epub 2020 Jun 5. 2020
|
| 4 | ENOSF1, TYMS
|
| Evaluating the role of ENOSF1 and TYMS variants as predictors in fluoropyrimidine-related toxicities: An IPD meta-analysis
|
| Hamzic S, Kummer D, Froehlich TK, Joerger M, Aebi S, Palles C, Thomlinson I, Meulendijks D, Schellens JHM, García-González X, López-Fernández LA, Amstutz U, Largiadèr CR.
|
| Pharmacol Res. Feb;152:104594. doi: 10.1016/j.phrs.2019.104594. Epub 2019 Dec 12. 2020
|
| 5 | TYMS
|
| TYMS presents a novel biomarker for diagnosis and prognosis in patients with pancreatic cancer
|
| Fu Z, Jiao Y, Li Y, Ji B, Jia B, Liu B.
|
| Medicine (Baltimore) Dec;98(51):e18487. doi: 10.1097/MD.0000000000018487 2019
|
| 6 | TYMS
|
| Inhibition of thymidylate synthase affects neural tube development in mice
|
| Wang X, Guan Z, Dong Y, Zhu Z, Wang J, Niu B.
|
| Reprod Toxicol Mar;76:17-25. doi: 10.1016/j.reprotox.2017.12.007. Epub 2017 Dec 16. 2018
|
| 7 | TYMS
|
| Oxidative Stress and Response to Thymidylate Synthase-Targeted Antimetabolites.
|
| Ozer U, Barbour KW, Clinton SA, Berger FG.
|
| Mol Pharmacol. Dec;88(6):970-81. doi: 10.1124/mol.115.099614. Epub 2015 Oct 6. 2015
|
| 8 | TYMS
|
| TYMS serves as a prognostic indicator to predict the lymph node metastasis in Chinese patients with colorectal cancer
|
| Lu Y, Zhuo C, Cui B, Liu Z, Zhou P, Lu Y, Wang B.
|
| Clin Biochem. Oct;46(15):1478-83. doi: 10.1016/j.clinbiochem.2013.06.017. Epub 2013 Jun 25. 2013
|
| 9 | DHFRL1, SHMT2, TYMS
|
| Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria.
|
| Anderson DD, Quintero CM, Stover PJ.
|
| Proc Natl Acad Sci U S A 108(37):15163-8. Epub 2011 Aug 26.
2011
|
| 10 | TYMS
|
| Reexamining a proposal: thymidylate synthase 5'-untranslated region as a regulator of translation efficiency.
|
| Ghosh S, Winter JM, Patel K, Kern SE.
|
| Cancer Biol Ther 12(8):750-5. Epub 2011 Oct 15.
2011
|
| 11 | TYMS
|
| Impact of thymidylate synthase promoter and DNA repair gene polymorphisms on susceptibility to childhood acute lymphoblastic leukemia.
|
| Canalle R, Silveira VS, Scrideli CA, Queiroz RG, Lopes LF, Tone LG.
|
| Leuk Lymphoma 52(6):1118-26. Epub 2011 Apr 4.
2011
|
| 12 | TYMS
|
| The association between two polymorphisms in the TYMS gene and breast cancer risk: a meta-analysis.
|
| Wang J, Wang B, Bi J, Di J.
|
| Breast Cancer Res Treat 128(1):203-9. Epub 2010 Dec 25.
2011
|
| 13 | TYMS
|
| Relationship between thymidylate synthase (TYMS) gene polymorphism and TYMS protein levels in patients with high-risk breast cancer.
|
| Fujishima M, Inui H, Hashimoto Y, Azumi T, Yamamoto N, Kato H, Hojo T, Yamato M, Matsunami N, Shiozaki H, Watatani M.
|
| Anticancer Res 30(10):4373-9.
2010
|
| 14 | TYMS
|
| Association of thymidylate synthase variants with 5-fluorouracil cytotoxicity.
|
| Peters EJ, Kraja AT, Lin SJ, Yen-Revollo JL, Marsh S, Province MA, McLeod HL.
|
| Pharmacogenet Genomics 19(5):399-401.
2009
|
| 15 | AHCY, FOLH1, MTHFD1, MTR, NNMT, PON1, TYMS
|
| Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm.
|
| Giusti B, Saracini C, Bolli P, Magi A, Sestini I, Sticchi E, Pratesi G, Pulli R, Pratesi C, Abbate R.
|
| J Med Genet 45(11):721-30. Epub 2008 Jul 17.
2008
|
| 16 | MTHFR, TYMS
|
| Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma.
|
| Yuan JM, Lu SC, Van Den Berg D, Govindarajan S, Zhang ZQ, Mato JM, Yu MC.
|
| Hepatology 46(3):749-58.
2007
|
| 17 | TYMS
|
| A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations.
|
| Kealey C, Brown KS, Woodside JV, Young I, Murray L, Boreham CA, McNulty H, Strain JJ, McPartlin J, Scott JM, Whitehead AS.
|
| Hum Genet 116(5):347-53. Epub 2005 Jan 29. 2005
|
| 18 | TYMS
|
| Association of thymidylate synthase polymorphisms with gastric cancer susceptibility.
|
| Graziano F, Kawakami K, Watanabe G, Ruzzo A, Humar B, Santini D, Catalano V, Ficarelli R, Merriman T, Panunzi S, Testa E, Cascinu S, Bearzi I, Tonini G, Magnani M.
|
| Int J Cancer 112(6):1010-4. 2004
|
| 19 | TYMS
|
| Differential alternative splicing expressions of thymidylate synthase isoforms.
|
| Hisatomi H, Tanemura H, Iizuka T, Katsumata K, Nagao K, Sumida H, Udagawa H, Hikiji K.
|
| Cancer Lett 193(2):127-31.
2003
|
| 20 | TYMS
|
| Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
|
| Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW.
|
| Hum Genet 111(3):299-302. 2002
|
| 21 | NDC80, TGIF1, TYMS, YES1
|
| Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas.
|
| Nakakuki K, Imoto I, Pimkhaokham A, Fukuda Y, Shimada Y, Imamura M, Amagasa T, Inazawa J.
|
| Carcinogenesis 23(1):19-24. 2002
|
| 22 | ADCYAP1, CLUL1, MAFD1, ENOSF1, TYMS, YES1
|
| Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.
|
| McInnes LA, Service SK, Reus VI, Barnes G, Charlat O, Jawahar S, Lewitzky S, Yang Q, Duong Q, Spesny M, Araya C, Araya X, Gallegos A, Meza L, Molina J, Ramirez R, Mendez R, Silva S, Fournier E, Batki SL, Mathews CA, Neylan T, Glatt CE, Escamilla MA, Luo D, Gajiwala P, Song T, Crook S, Nguyen JB, Roche E, Meyer JM, Leon P, Sandkuijl LA, Freimer NB, Chen H.
|
| Proc Natl Acad Sci U S A 98(20):11485-90. 2001
|
| 23 | CDKN1A, TYMS
|
| Downregulation of p21/WAF1 expression by thymidylate synthase.
|
| Kastanos EK, Zajac-Kaye M, Dennis PA, Allegra CJ.
|
| Biochem Biophys Res Commun 285(2):195-200. 2001
|
| 24 | TYMS
|
| Regional assignment of the human thymidylate synthase (TS) gene to chromosome band 18p11.32 by nonisotopic in situ hybridization.
|
| Hori T, et al.
|
| Hum Genet 85 : 576-580. 1990
|
| 25 | TYMS
|
| Assignment of the human TMS gene, encoding thymidylate synthase, to chromosome 18.
|
| Hori T, et al.
|
| (HGM8) Cytogenet Cell Genet 40 : 654-655. 1985
|