| 1 | HNRNPH1, HNRNPH2, TYMP
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| Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.
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| Stark M, Bram EE, Akerman M, Mandel-Gutfreund Y, Assaraf YG.
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| J Biol Chem 286(5):3741-54. doi: 10.1074/jbc.M110.163444. Epub 2010 Nov 10.
2011
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| 2 | COX10, PINK1, TYMP
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| Therapeutic prospects for mitochondrial disease.
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| Schon EA, DiMauro S, Hirano M, Gilkerson RW.
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| Trends Mol Med. 16(6):268-76. 2010
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| 3 | TYMP
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| Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach.
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| Halter J, Schüpbach WM, Casali C, Elhasid R, Fay K, Hammans S, Illa I, Kappeler L, Krähenbühl S, Lehmann T, Mandel H, Marti R, Mattle H, Orchard K, Savage D, Sue CM, Valcarcel D, Gratwohl A, Hirano M.
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| Bone Marrow Transplant. 2010
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| 4 | TYMP
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| Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice.
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| López LC, Akman HO, García-Cazorla A, Dorado B, Martí R, Nishino I, Tadesse S, Pizzorno G, Shungu D, Bonilla E, Tanji K, Hirano M.
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| Hum Mol Genet. 18(4):714-22. 2009
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| 5 | BNIP3, TYMP
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| Thymidine phosphorylase inhibits the expression of proapoptotic protein BNIP3.
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| Ikeda R, Tajitsu Y, Iwashita K, Che XF, Yoshida K, Ushiyama M, Furukawa T, Komatsu M, Yamaguchi T, Shibayama Y, Yamamoto M, Zhao HY, Arima J, Takeda Y, Akiyama S, Yamada K.
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| Biochem Biophys Res Commun 370(2):220-4. Epub 2008 Mar 24.
2008
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| 6 | TYMP
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| Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.
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| Gotanda T, Haraguchi M, Tachiwada T, Shinkura R, Koriyama C, Akiba S, Kawahara M, Nishiyama K, Sumizawa T, Furukawa T, Mimata H, Nomura Y, Akiyama S, Nakagawa M.
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| Int J Mol Med 17(6):1085-91. 2006
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| 7 | TYMP
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| Pre- and post-dialysis quantitative dosage of thymidine in urine and plasma of a MNGIE patient by using HPLC-ESI-MS/MS.
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| la Marca G, Malvagia S, Casetta B, Pasquini E, Pela I, Hirano M, Donati MA, Zammarchi E.
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| J Mass Spectrom. 41(5):586-92. 2006
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| 8 | TYMP
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| Infusion of platelets transiently reduces nucleoside overload in MNGIE.
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| Lara MC, Weiss B, Illa I, Madoz P, Massuet L, Andreu AL, Valentino ML, Anikster Y, Hirano M, Martí R.
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| Neurology. 67(8):1461-3. 2006
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| 9 | TYMP, MNGIE
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| A novel thymidine phosphorylase mutation in a Spanish MNGIE patient.
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| Gamez J, Lara MC, Mearin F, Oliveras-Ley C, Raguer N, Olive M, Leist AT, Perello A, Perona M, Cervera C, Andreu AL, Marti R, Hirano M.
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| J Neurol Sci 228(1):35-9. Epub 2004 Nov 12. 2005
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| 10 | TYMP, MNGIE
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| Thymidine phosphorylase gene mutations in patients with mitochondrial neurogastrointestinal encephalomyopathy syndrome.
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| Slama A, Lacroix C, Plante-Bordeneuve V, Lombes A, Conti M, Reimund JM, Auxenfants E, Crenn P, Laforet P, Joannard A, Seguy D, Pillant H, Joly P, Haut S, Messing B, Said G, Legrand A, Guiochon-Mantel A.
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| Mol Genet Metab 84(4):326-31. Epub 2005 Jan 24. 2005
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| 11 | TYMP
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| Clinicopathological aspects of the neuropathy of neurogastrointestinal encephalomyopathy (MNGIE) in four patients including two with a Charcot-Marie-Tooth presentation.
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| Said G, Lacroix C, Plante-Bordeneuve V, Messing B, Slama A, Crenn P, Nivelon-Chevallier A, Bedenne L, Soichot P, Manceau E, Rigaud D, Guiochon-Mantel A, Matuchansky C.
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| J Neurol 252(6):655-62. Epub 2005 Mar 7. 2005
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| 12 | MNGIE, TYMP
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| MNGIE with lack of skeletal muscle involvement and a novel TP splice site mutation.
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| Szigeti K, Wong LJ, Perng CL, Saifi GM, Eldin K, Adesina AM, Cass DL, Hirano M, Lupski JR, Scaglia F.
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| J Med Genet 41(2):125-9. 2004
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| 13 | TYMP, MNGIE
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| Four novel thymidine phosphorylase gene mutations in mitochondrial neurogastrointestinal encephalomyopathy syndrome (MNGIE) patients.
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| Kocaefe YC, Erdem S, Ozguc M, Tan E.
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| Eur J Hum Genet 11(1):102-4. 2003
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| 14 | TYMP
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| Significance of monocyte chemotactic protein-1 and thymidine phosphorylase in angiogenesis of human cardiac myxoma.
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| Zhang T, Koide N, Wada Y, Tsukioka K, Takayama K, Kono T, Kitahara H, Amano J.
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| Circ J 67(1):54-60. 2003
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| 15 | TYMP
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| Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice.
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| Haraguchi M, Tsujimoto H, Fukushima M, Higuchi I, Kuribayashi H, Utsumi H, Nakayama A, Hashizume Y, Hirato J, Yoshida H, Hara H, Hamano S, Kawaguchi H, Furukawa T, Miyazono K, Ishikawa F, Toyoshima H, Kaname T, Komatsu M, Chen ZS, Gotanda T, Tachiwada T, Sumizawa T, Miyadera K, Osame M, Yoshida H, Noda T, Yamada Y, Akiyama S.
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| Mol Cell Biol. 22(14):5212-21. 2002
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| 16 | TYMP
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| Altered thymidine metabolism due to defects of thymidine phosphorylase.
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| Spinazzola A, Marti R, Nishino I, Andreu AL, Naini A, Tadesse S, Pela I, Zammarchi E, Donati MA, Oliver JA, Hirano M.
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| J Biol Chem. 277(6):4128-33. 2002
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| 17 | TYMP
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| Role of thymidine phosphorylase in Fas-induced apoptosis.
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| Mori S, Takao S, Ikeda R, Noma H, Mataki Y, Wang X, Akiyama S, Aiko T.
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| Hum Cell 14(4):323-30. 2001
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| 18 | MNGIE, TYMP
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| Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder.
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| Nishino I, Spinazzola A, Hirano M.
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| Science 283(5402):689-92. 1999
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| 19 | TYMP
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| Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis.
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| Brown NS, Bicknell R.
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| Biochem J 334 ( Pt 1):1-8. Review. 1998
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| 20 | TYMP
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| Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome 22q13.
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| Stenman G, Sahlin P, Dumanski JP, Hagiwara K, Ishikawa F, Miyazono K, Collins VP, Heldin CH.
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| Cytogenet Cell Genet 59 : 22-23. 1992
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| 21 | TYMP
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| Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity.
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| Usuki K, Saras J, Waltenberger J, Miyazono K, Pierce G, Thomason A, Heldin CH.
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| Biochem Biophys Res Commun. 184(3):1311-6. 1992
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| 22 | TYMP
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| Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene.
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| Hagiwara K, Stenman G, Honda H, Sahlin P, Andersson A, Miyazono K, Heldin CH, Ishikawa F, Takaku F.
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| Mol Cell Biol 11 : 2125-2132. 1991
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| 23 | TYMP
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| Platelet-derived endothelial cell growth factor.
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| Miyazono K, Usuki K, Heldin CH.
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| Prog Growth Factor Res 3 : 207-217. 1991
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