Citations for
Structural basis for a novel interaction between TXNIP and Vav2.
Liu S, Wu X, Zong M, Tempel W, Loppnau P, Liu Y.
FEBS Lett 590(6):857-65. doi: 10.1002/1873-3468.12110. Epub 2016 Mar 4. 2016
TXNIP interacts with hEcd to increase p53 stability and activity.
Suh HW, Yun S, Song H, Jung H, Park YJ, Kim TD, Yoon SR, Choi I.
Biochem Biophys Res Commun 438(2):264-9. doi: 10.1016/j.bbrc.2013.07.036. Epub 2013 Jul 21. 2013
A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis.
Zervou S, Ray T, Sahgal N, Sebag-Montefiore L, Cross R, Medway DJ, Ostrowski PJ, Neubauer S, Lygate CA.
Am J Physiol Endocrinol Metab 305(2):E263-70. doi: 10.1152/ajpendo.00637.2012. Epub 2013 May 28. 2013
Induction of the metabolic regulator Txnip in fasting-induced and natural torpor.
Hand LE, Saer BR, Hui ST, Jinnah HA, Steinlechner S, Loudon AS, Bechtold DA.
Endocrinology 154(6):2081-91. doi: 10.1210/en.2012-2051. Epub 2013 Apr 12. 2013
Structure of the N-terminal domain of human thioredoxin-interacting protein.
Polekhina G, Ascher DB, Kok SF, Beckham S, Wilce M, Waltham M.
Acta Crystallogr D Biol Crystallogr 69(Pt 3):333-44. doi: 10.1107/S0907444912047099. Epub 2013 Feb 16. 2013
Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer.
Zhou J, Chng WJ.
Mitochondrion 13(3):163-9. doi: 10.1016/j.mito.2012.06.004. Epub 2012 Jun 27. Review. 2013
Posttranslational regulation of thioredoxin-interacting protein.
Robinson KA, Brock JW, Buse MG.
J Mol Endocrinol 50(1):59-71. doi: 10.1530/JME-12-0091. Print 2013 Feb. 2012
TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity.
Blouet C, Liu SM, Jo YH, Chua S, Schwartz GJ.
J Neurosci 32(29):9870-7. doi: 10.1523/JNEUROSCI.0353-12.2012. 2012
TXNIP links innate host defense mechanisms to oxidative stress and inflammation in retinal Muller glia under chronic hyperglycemia: implications for diabetic retinopathy.
Devi TS, Lee I, Hüttemann M, Kumar A, Nantwi KD, Singh LP.
Exp Diabetes Res 2012:438238. doi: 10.1155/2012/438238. Epub 2012 Mar 18. 2012
TXNIP potentiates Redd1-induced mTOR suppression through stabilization of Redd1.
Jin HO, Seo SK, Kim YS, Woo SH, Lee KH, Yi JY, Lee SJ, Choe TB, Lee JH, An S, Hong SI, Park IC.
Oncogene 30(35):3792-801. doi: 10.1038/onc.2011.102. Epub 2011 Apr 4. 2011
TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms.
Zhou J, Yu Q, Chng WJ.
Int J Biochem Cell Biol 43(12):1668-73. doi: 10.1016/j.biocel.2011.09.005. Epub 2011 Sep 24. Review. 2011
Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability.
Chutkow WA, Lee RT.
J Biol Chem 286(33):29139-45. doi: 10.1074/jbc.M111.267666. Epub 2011 Jun 24. 2011
Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity.
Al-Gayyar MM, Abdelsaid MA, Matragoon S, Pillai BA, El-Remessy AB.
Br J Pharmacol 164(1):170-80. doi: 10.1111/j.1476-5381.2011.01336.x. 2011
AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells.
Shaked M, Ketzinel-Gilad M, Cerasi E, Kaiser N, Leibowitz G.
PLoS One 6(12):e28804. doi: 10.1371/journal.pone.0028804. Epub 2011 Dec 14. Erratum in: PLoS One. 2012;7(1). doi:10.1371/annotation/23f84 2011
The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation.
Zhang P, Wang C, Gao K, Wang D, Mao J, An J, Xu C, Wu D, Yu H, Liu JO, Yu L.
J Biol Chem 285(12):8869-79. Epub 2010 Jan 12.PMID: 20068034 2010
RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion.
Sbai O, Devi TS, Melone MA, Feron F, Khrestchatisky M, Singh LP, Perrone L.
J Cell Sci 123(Pt 24):4332-9. Epub 2010 Nov 23. 2010
Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells.
Li X, Rong Y, Zhang M, Wang XL, LeMaire SA, Coselli JS, Zhang Y, Shen YH.
Biochem Biophys Res Commun 381(4):660-5. Epub 2009 Feb 28. 2009
Thioredoxin-interacting Protein (Txnip) Is a Critical Regulator of Hepatic Glucose Production.
Chutkow WA, Patwari P, Yoshioka J, Lee RT.
J Biol Chem 283(4):2397-406. Epub 2007 Nov 12. 2008
hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip.
Shin KH, Kim RH, Kim RH, Kang MK, Park NH.
Biochem Biophys Res Commun 372(4):880-5. Epub 2008 Jun 9. 2008
Can we exclude the TXNIP gene as a candidate gene for familial combined hyperlipidemia?
Van der Vleuten GM, Hijmans A, Heil S, Blom HJ, Stalenhoef AF, de Graaf J.
Am J Med Genet A 140(9):1010-2. No abstract available. 2006
Characterization of the expression of the hypoxia-induced genes neuritin, TXNIP and IGFBP3 in cancer.
Le Jan S, Le Meur N, Cazes A, Philippe J, Le Cunff M, Leger J, Corvol P, Germain S.
FEBS Lett 580(14):3395-400. Epub 2006 May 11. 2006
The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.
Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT.
J Biol Chem 281(31):21884-91. Epub 2006 Jun 9. 2006
Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein.
Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Wang P, Kendziorski C, Shalev A.
Biochem Biophys Res Commun 336(3):770-8. 2005
Heat shock factor regulates VDUP1 gene expression.
Kim KY, Shin SM, Kim JK, Paik SG, Yang Y, Choi I.
Biochem Biophys Res Commun 315(2):369-75. 2004
VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression.
Han SH, Jeon JH, Ju HR, Jung U, Kim KY, Yoo HS, Lee YH, Song KS, Hwang HM, Na YS, Yang Y, Lee KN, Choi I.
Oncogene 22(26):4035-46. 2003
The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes.
Champliaud MF, Viel A, Baden HP.
J Invest Dermatol 121(4):781-5. 2003
Isolation and characterization of a novel cDNA from HL-60 cells treated with1,25-dihydroxyvitamin D-3.
Chen KS, DeLuca HF.
Biochim Biophys Acta 1219(1):26-32. 1994