1 | MAP3K5, TXN
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| Cysteine residues mediate high-affinity binding of thioredoxin to ASK1.
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| Kylarova S, Kosek D, Petrvalska O, Psenakova K, Man P, Vecer J, Herman P, Obsilova V, Obsil T.
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| FEBS J 283(20):3821-3838. doi: 10.1111/febs.13893. Epub 2016 Sep 18.
2016
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2 | TXN, TXNDC17
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| Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase
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| Pader I, Sengupta R, Cebula M, Xu J, Lundberg JO, Holmgren A, Johansson K, Arnér ES.
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| Proc Natl Acad Sci U S A. May 13;111(19):6964-9. doi: 10.1073/pnas.1317320111. Epub 2014 Apr 28. 2014
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3 | NFE2L2, PARK7, TXN
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| DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway.
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| Im JY, Lee KW, Woo JM, Junn E, Mouradian MM.
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| Hum Mol Genet 21(13):3013-24. doi: 10.1093/hmg/dds131. Epub 2012 Apr 5.
2012
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4 | ADAM17, TXN
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| Identification of novel interaction between ADAM17 (a disintegrin and metalloprotease 17) and thioredoxin-1.
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| Aragão AZ, Nogueira ML, Granato DC, Simabuco FM, Honorato RV, Hoffman Z, Yokoo S, Laurindo FR, Squina FM, Zeri AC, Oliveira PS, Sherman NE, Paes Leme AF.
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| J Biol Chem. Dec 14;287(51):43071-82. doi: 10.1074/jbc.M112.364513. Epub 2012 Oct 26. 2012
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5 | TGM2, TXN
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| Activation of extracellular transglutaminase 2 by thioredoxin.
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| Jin X, Stamnaes J, Klöck C, DiRaimondo TR, Sollid LM, Khosla C.
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| J Biol Chem 286(43):37866-73. Epub 2011 Sep 9.
2011
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6 | TXN
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| Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor.
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| Ito T, Yamakuchi M, Lowenstein CJ.
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| J Biol Chem 286(13):11179-84. Epub 2011 Feb 15.
2011
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7 | TXN
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| Oxidative stress-induced degradation of thioredoxin-1 and apoptosis is inhibited by thioredoxin-1-actin interaction in endothelial cells.
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| Zschauer TC, Kunze K, Jakob S, Haendeler J, Altschmied J.
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| Arterioscler Thromb Vasc Biol 31(3):650-6. Epub 2011 Jan 6.
2011
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8 | TXN, TXN2
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| Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells.
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| Song JS, Cho HH, Lee BJ, Bae YC, Jung JS.
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| Stem Cells Dev 20(9):1529-37. Epub 2011 Jan 31.
2011
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9 | TXN
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| Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress.
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| Mougiakakos D, Johansson CC, Jitschin R, Böttcher M, Kiessling R.
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| Blood 117(3):857-61. Epub 2010 Oct 28.
2011
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10 | TXN
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| Thioredoxin 1 as a subcellular biomarker of redox imbalance in human prostate cancer progression.
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| Shan W, Zhong W, Zhao R, Oberley TD.
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| Free Radic Biol Med 49(12):2078-87. Epub 2010 Oct 16.
2010
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11 | TXN, TXN2
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| Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
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| Weichsel A, Kem M, Montfort WR.
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| Protein Sci 19(9):1801-6.
2010
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12 | TXN
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| Structure of human thioredoxin exhibits a large conformational change.
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| Hall G, Emsley J.
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| Protein Sci 19(9):1807-11.
2010
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13 | TXN
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| Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts.
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| Young JJ, Patel A, Rai P.
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| Biochem Biophys Res Commun 392(3):363-8. Epub 2010 Jan 13.
2010
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14 | TXN
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| Direct association of thioredoxin-1 (TRX) with macrophage migration inhibitory factor (MIF): regulatory role of TRX on MIF internalization and signaling.
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| Son A, Kato N, Horibe T, Matsuo Y, Mochizuki M, Mitsui A, Kawakami K, Nakamura H, Yodoi J.
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| Antioxid Redox Signal 11(10):2595-605.
2009
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15 | TXN
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| Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma.
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| Cha MK, Suh KH, Kim IH.
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| J Exp Clin Cancer Res 28:93.
2009
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16 | TXN
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| Thioredoxin 1 delivery as new therapeutics.
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| Nakamura H, Hoshino Y, Okuyama H, Matsuo Y, Yodoi J.
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| Adv Drug Deliv Rev 61(4):303-9. Review.
2009
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17 | DYNLL1, TXN, TXNDC17
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| Thioredoxin-related protein 14, a new member of the thioredoxin family with disulfide reductase activity: implication in the redox regulation of TNF-alpha signaling.
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| Jeong W, Jung Y, Kim H, Park SJ, Rhee SG.
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| Free Radic Biol Med. Nov 1;47(9):1294-303. doi: 10.1016/j.freeradbiomed.2009.07.021. Epub 2009 Jul 21. 2009
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18 | TXN
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| Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production.
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| Kim SH, Oh J, Choi JY, Jang JY, Kang MW, Lee CE.
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| BMC Immunol 9:64.
2008
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19 | TXN, TXN2
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| Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha.
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| Zhou J, Damdimopoulos AE, Spyrou G, Brüne B.
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| J Biol Chem 282(10):7482-90. Epub 2007 Jan 12.
2007
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20 | TNFRSF8, TXN
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| Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.
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| Schwertassek U, Balmer Y, Gutscher M, Weingarten L, Preuss M, Engelhard J, Winkler M, Dick TP.
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| EMBO J 26(13):3086-97. Epub 2007 Jun 7.
2007
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21 | TXN,TXNIP
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| The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.
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| Patwari P, Higgins LJ, Chutkow WA, Yoshioka J, Lee RT.
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| J Biol Chem 281(31):21884-91. Epub 2006 Jun 9. 2006
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22 | TXN
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| Mitochondrial thioredoxin in regulation of oxidant-induced cell death.
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| Chen Y, Cai J, Jones DP.
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| FEBS Lett 580(28-29):6596-602. Epub 2006 Nov 14. 2006
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23 | TXN
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| Human lens thioredoxin: molecular cloning and functional characterization.
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| Yegorova S, Liu A, Lou MF.
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| Invest Ophthalmol Vis Sci 44(8):3263-71. 2003
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24 | TXNP, TXN
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| Thioredoxin, a mediator of growth inhibition, maps to 9q31.
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| Heppell-Parton A, et al.
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| Genomics 26 : 379-381. 1995
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25 | TXN
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| Genomic cloning of human thioredoxin-encoding gene : mapping of the transcription start point and analysis of the promoter.
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| Kaghad M, et al.
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| Gene 140 : 273-278. 1994
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26 | TXN
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| The gene for human thioredoxin maps on the short arm of chromosome 3 at bands 3p11-p12.
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| Lafage-Pochitaloff-HuvalŽ M, et al.
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| FEBS Lett 255 : 89-91. 1989
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27 | TXN
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| Cloning and expression of a cDNA for human thioredoxin.
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| Wollman EE, et al.
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| J Biol Chem 263 : 15506-15512. 1988
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