1 | CALCOCO2, N4BP1, RIOK3, RNF114, TTC3, UBFD1, ZFAND3, ZFAND6
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| Identification of polyubiquitin binding proteins involved in NF-kappaB signaling using protein arrays.
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| Fenner BJ, Scannell M, Prehn JH.
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| Biochim Biophys Acta 1794(7):1010-6. Epub 2009 Mar 11. 2009
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2 | CIT, RHOA, TTC3
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| The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase.
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| Berto G, Camera P, Fusco C, Imarisio S, Ambrogio C, Chiarle R, Silengo L, Di Cunto F.
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| J Cell Sci 120(Pt 11):1859-67. Epub 2007 May 8.
2007
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3 | DNAJC7, TTC1, TTC3
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| Molecular characterization of the mouse mtprd gene, a homologue of human TPRD: unique gene expression suggesting its critical role in the pathophysiology of Down syndrome.
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| Tsukahara F, Urakawa I, Hattori M, Hirai M, Ohba K, Yoshioka T, Sakaki Y, Muraki T.
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| J Biochem 123(6):1055-63.
1998
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4 | TTC3
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| Cloning and characterization of novel gene, DCRR1, expressed from Down's syndrome critical region of human chromosome 21q22.2.
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| Eki T, Abe M, Naitou M, Sasanuma SI, Nohata J, Kawashima K, Ahmad I, Hanaoka F, Murakami Y.
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| DNA Seq 7(3-4):153-64. 1997
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5 | TTC3, RCAN1, DYRK1A, KCNJ6
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| Cosmid contig and transcriptional map of three regions of human chromosome 21q22: identification of 37 novel transcripts by direct selection.
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| Guimera J, Pucharcos C, Domenech A, Casas C, Solans A, Gallardo T, Ashley J, Lovett M, Estivill X, Pritchard M.
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| Genomics 45(1):59-67. 1997
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6 | TTC1, DNAJC7, TTC3
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| Identification and cloning of a novel cDNA belonging to tetratricopeptide repeat gene family from Down syndrome-critical region 21q22.2.
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| Tsukahara F, Hattori M, Muraki T, Sakaki Y.
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| J Biochem (Tokyo) 120(4):820-7. 1996
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7 | TTC1, TTC3
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| Identification of a novel human gene containing the tetratricopeptide repeat domain from the Down syndrome region of chromosome 21.
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| Ohira M, Ootsuyama A, Suzuki E, Ichikawa H, Seki N, Nagase T, Nomura N, Ohki M.
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| DNA Res 3(1):9-16. 1996
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