| 1 | SCA11, TTBK2
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| Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.
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| Bowie E, Norris R, Anderson KV, Goetz SC.
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| PLoS Genet 14(12):e1007844. doi: 10.1371/journal.pgen.1007844. eCollection 2018 Dec.
2018
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| 2 | TTBK1, TTBK2
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| Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.
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| Taylor LM, McMillan PJ, Liachko NF, Strovas TJ, Ghetti B, Bird TD, Keene CD, Kraemer BC.
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| Mol Neurodegener 13(1):7. doi: 10.1186/s13024-018-0237-9.
2018
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| 3 | GRIK2, TTBK2
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| Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2.
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| Nieding K, Matschke V, Meuth SG, Lang F, Seebohm G, Strutz-Seebohm N.
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| Cell Physiol Biochem 39(4):1444-52. doi: 10.1159/000447847. Epub 2016 Sep 9.
2016
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| 4 | MCRS1, TTBK2
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| MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.
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| Lee SH, Lee MS, Choi TI, Hong H, Seo JY, Kim CH, Kim J.
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| Sci Rep 6:27284. doi: 10.1038/srep27284.
2016
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| 5 | KIF2A, MAPRE1, MAPRE1, TTBK2
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| TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
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| Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K.
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| J Cell Biol 210(5):737-51. doi: 10.1083/jcb.201412075.
2015
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| 6 | TTBK2
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| TTBK2: a tau protein kinase beyond tau phosphorylation.
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| Liao JC, Yang TT, Weng RR, Kuo CT, Chang CW.
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| Biomed Res Int 2015:575170. doi: 10.1155/2015/575170. Epub 2015 Apr 9. Review.
2015
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| 7 | CEP164, CEP97, TTBK2
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| Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis.
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| Oda T, Chiba S, Nagai T, Mizuno K.
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| Genes Cells 19(12):927-40. doi: 10.1111/gtc.12191. Epub 2014 Oct 9.
2014
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| 8 | ALS10, TARDBP, TTBK1, TTBK2
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| The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
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| Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC.
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| PLoS Genet LoS Genet. 2014 2014
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| 9 | CEP164, TTBK2
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| Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole.
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| Čajánek L, Nigg EA.
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| Proc Natl Acad Sci U S A 111(28):E2841-50. doi: 10.1073/pnas.1401777111. Epub 2014 Jun 30.
2014
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| 10 | CCP110, TTBK2
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| TTBK2 kinase: linking primary cilia and cerebellar ataxias.
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| Jackson PK.
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| Cell 151(4):697-699. doi: 10.1016/j.cell.2012.10.027.
2012
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| 11 | CCP110, SCA11, TTBK2
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| The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
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| Goetz SC, Liem KF Jr, Anderson KV.
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| Cell 151(4):847-858. doi: 10.1016/j.cell.2012.10.010.
2012
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| 12 | SCA11, TTBK2
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| TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development.
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| Bouskila M, Esoof N, Gay L, Fang EH, Deak M, Begley MJ, Cantley LC, Prescott A, Storey KG, Alessi DR.
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| Biochem J 437(1):157-67.
2011
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| 13 | SCA11, TTBK2
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| Spinocerebellar ataxia type 11 (SCA11) is an uncommon cause of dominant ataxia among French and German kindreds.
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| Bauer P, Stevanin G, Beetz C, Synofzik M, Schmitz-Hübsch T, Wüllner U, Berthier E, Ollagnon-Roman E, Riess O, Forlani S, Mundwiller E, Durr A, Schöls L, Brice A.
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| J Neurol Neurosurg Psychiatry 81(11):1229-32. doi: 10.1136/jnnp.2009.202150. Epub 2010 Jul 28.
2010
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| 14 | SCA11, TTBK2
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| Spinocerebellar ataxia type 11 in the Chinese Han population.
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| Xu Q, Li X, Wang J, Yi J, Lei L, Shen L, Jiang H, Xia K, Pan Q, Tang B.
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| Neurol Sci 31(1):107-9. doi: 10.1007/s10072-009-0129-4. Epub 2009 Sep 19.
2010
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| 15 | SCA11, TTBK2
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| Missense exchanges in the TTBK2 gene mutated in SCA11.
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| Edener U, Kurth I, Meiner A, Hoffmann F, Hübner CA, Bernard V, Gillessen-Kaesbach G, Zühlke C.
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| J Neurol 256(11):1856-9. Epub 2009 Jun 17.
2009
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| 16 | TTBK2, SCA11
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| Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.
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| Houlden H, Johnson J, Gardner-Thorpe C, Lashley T, Hernandez D, Worth P, Singleton AB, Hilton DA, Holton J, Revesz T, Davis MB, Giunti P, Wood NW.
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| Nat Genet 39(12):1434-6. Epub 2007 Nov 25. 2007
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| 17 | TTBK2
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| Expression, purification and crystallization of a human tau-tubulin kinase 2 that phosphorylates tau protein.
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| Kitano-Takahashi M, Morita H, Kondo S, Tomizawa K, Kato R, Tanio M, Shirota Y, Takahashi H, Sugio S, Kohno T.
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| Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 7):602-4. Epub 2007 Jun 15.
2007
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| 18 | CDAN1, STARD9, TTBK2, VPS39
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| Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1.
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| Dgany O, Avidan N, Delaunay J, Krasnov T, Shalmon L, Shalev H,Eidelitz-Markus T, Kapelushnik J, Cattan D, Pariente A, Tulliez M, Cretien A,Schischmanoff PO, Iolascon A, Fibach E, Koren A, Rossler J, Le Merrer M, YanivI, Zaizov R, Ben-Asher E, Olender T, Lancet D, Beckmann JS, Tamary H.
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| Am J Hum Genet 71(6):1467-74. Epub 2002 Nov 14. 2002
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