1 | MED1, TSHB
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| Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter.
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| Matsui K, Oda K, Mizuta S, Ishino R, Urahama N, Hasegawa N, Roeder RG, Ito M.
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| Biochem Biophys Res Commun 440(1):184-9. doi: 10.1016/j.bbrc.2013.09.061. Epub 2013 Sep 18.
2013
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2 | TSHB
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| PPARα modulates the TSH β-subunit mRNA expression in thyrotrope TαT1 cells and in a mouse model.
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| Wege N, Schutkowski A, König B, Brandsch C, Weiwad M, Stangl GI.
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| Mol Nutr Food Res 57(3):376-89. doi: 10.1002/mnfr.201200409. Epub 2012 Dec 18.
2013
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3 | TRH, TSHB
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| NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice.
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| Nakajima Y, Yamada M, Taguchi R, Shibusawa N, Ozawa A, Tomaru T, Hashimoto K, Saito T, Tsuchiya T, Okada S, Satoh T, Mori M.
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| PLoS One 7(7):e40437. doi: 10.1371/journal.pone.0040437. Epub 2012 Jul 9.
2012
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4 | TSHB
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| A newly identified TSHβ splice variant is involved in the pathology of Hashimoto's thyroiditis.
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| Liu C, Li L, Ying F, Xu C, Zang X, Gao Z.
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| Mol Biol Rep 39(12):10019-30. doi: 10.1007/s11033-012-1871-x. Epub 2012 Jul 3.
2012
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5 | GATA2, THRB, TSHB
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| Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter.
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| Figueira AC, Polikarpov I, Veprintsev D, Santos GM.
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| PLoS One 5(9):e12628. doi: 10.1371/journal.pone.0012628.
2010
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6 | CHNG4, TSHB
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| Two novel mutations of the TSH-beta subunit gene underlying congenital central hypothyroidism undetectable in neonatal TSH screening.
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| Baquedano MS, Ciaccio M, Dujovne N, Herzovich V, Longueira Y, Warman DM, Rivarola MA, Belgorosky A.
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| J Clin Endocrinol Metab 95(9):E98-103. doi: 10.1210/jc.2010-0223. Epub 2010 Jun 9. 2010
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7 | EYA3, SIX1, TSHB
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| Acute induction of Eya3 by late-night light stimulation triggers TSHβ expression in photoperiodism.
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| Masumoto KH, Ukai-Tadenuma M, Kasukawa T, Nagano M, Uno KD, Tsujino K, Horikawa K, Shigeyoshi Y, Ueda HR.
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| Curr Biol 20(24):2199-206. doi: 10.1016/j.cub.2010.11.038. Epub 2010 Dec 2.
2010
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8 | NFIB, TSHB
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| Insulin represses transcription of the thyroid stimulating hormone beta-subunit gene through increased recruitment of nuclear factor I.
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| Kim KK, Park KS, Song SB, Kim KE.
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| J Biol Chem 285(42):32003-11. doi: 10.1074/jbc.M110.107573. Epub 2010 Aug 4.
2010
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9 | TSHB, TSHR
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| TSH is a negative regulator of skeletal remodeling.
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| Abe E, Marians RC, Yu W, Wu XB, Ando T, Li Y, Iqbal J, Eldeiry L, Rajendren G, Blair HC, Davies TF, Zaidi M.
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| Cell 115(2):151-62. 2003
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10 | GATA2, TSHB
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| Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSH beta gene.
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| Gordon DF, Woodmansee WW, Black JN, Dowding JM, Bendrick-Peart J, Wood WM, Ridgway EC.
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| Mol Cell Endocrinol 196(1-2):53-66.
2002
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11 | TSHB
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| A circulating, biologically inactive thyrotropin caused by a mutation inthe beta subunit gene.
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| Medeiros-Neto G, et al.
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| J Clin Invest 97 : 1250-1256. 1996
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12 | CHNG4, TSHB
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| Rapid detection of a point mutation in thyroid-stimulating hormone beta-subunit gene causing congenital isolated thyroid-stimulating hormone deficiency.
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| Mori R, Sawai T, Kinoshita E, Baba T, Matsumoto T, Yoshimoto M, Tsuji Y, Satake Y, Sawada K.
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| Jpn J Hum Genet 36(4):313-6. 1991
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13 | CHNG4, TSHB
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| Familial hypothyroidism caused by a nonsense mutation in the thyroid-stimulating hormone beta-subunit gene.
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| Dacou-Voutetakis C, et al.
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| Am J Hum Genet 46 : 988-993. 1990
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14 | TSHB
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| Chromosome regional mapping for the human thyroid stimulating hormone beta subunit (TSHB) gene.
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| Tokino T, et al.
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| Cytogenet Cell Genet 53 : 140-143. 1990
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15 | NGF, TSHB
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| Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB) are located less than 310 kb apart in both human and mouse genomes.
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| Dracopoli NC, et al.
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| Genomics 3 : 161-167. 1988
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16 | TSHB
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| Polymorphism and mapping of the beta subunit of human thyroid stimulating hormone (TSHB).
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| Dracopoli NC, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 608. 1987
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17 | GAST, ERBB2, TSHB
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| Chromosomal assignment of human genes for gastrin, thyrotropin (TSH0)beta subunit and C-erbB-2 by chromosome sorting combined with velocity sedimentation and Southern hybridization.
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| Fukushige S, et al.
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| Biochem Biophys Res Commun 134 : 477-483. 1986
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18 | TSHB
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| Assignment of the gene for beta subunit of thyroid-stimulating hormone to the short arm of human chromosome 1.
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| Dracopoli NC, et al.
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| Proc Natl Acad Sci U S A 83 : 1822-1826. 1986
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19 | TSHB
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| Assignment of the structural gene for the beta subunit of thyroidstimulating hormone to human chromosome 1p22.
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| Dracopoli NC, et al.
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| (HGM8) Cytogenet Cell Genet 40 : 619. 1985
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20 | TSHB
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| Familial isolated thyrotropin deficiency with cretinism.
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| Miyai K, et al.
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| N Engl J Med 285 : 1043-1048. 1971
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