| 1 | MVB12A, MVB12B, TSG101, VPS28, VPS37A
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| A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission
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| Flower TG, Takahashi Y, Hudait A, Rose K, Tjahjono N, Pak AJ, Yokom AL, Liang X, Wang HG, Bouamr F, Voth GA, Hurley JH.
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| Nat Struct Mol Biol. Jun;27(6):570-580. doi: 10.1038/s41594-020-0426-4. Epub 2020 May 18 2020
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| 2 | LRSAM1, TSG101, VPS28
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| Deregulation of LRSAM1 expression impairs the levels of TSG101, UBE2N, VPS28, MDM2 and EGFR.
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| Minaidou A, Nicolaou P, Christodoulou K.
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| PLoS One 14(2):e0211814. doi: 10.1371/journal.pone.0211814. eCollection 2019.
2019
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| 3 | BLOC1S1, SNX2, TSG101
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| Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor into endosomal compartments.
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| Zhang A, He X, Zhang L, Yang L, Woodman P, Li W.
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| J Biol Chem 289(42):29180-94. doi: 10.1074/jbc.M114.576561. Epub 2014 Sep 2.
2014
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| 4 | BBS1, BBS4, TSG101
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| Basal body proteins regulate Notch signaling through endosomal trafficking.
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| Leitch CC, Lodh S, Prieto-Echagüe V, Badano JL, Zaghloul NA.
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| J Cell Sci. Jun 1;127(Pt 11):2407-19. doi: 10.1242/jcs.130344. Epub 2014 Mar 28 2014
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| 5 | CDKN1A, TSG101
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| Identification of TSG101 functional domains and p21 loci required for TSG101-mediated p21 gene regulation.
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| Lin YS, Chen YJ, Cohen SN, Cheng TH.
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| PLoS One 8(11):e79674. doi: 10.1371/journal.pone.0079674. eCollection 2013.
2013
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| 6 | RAB7A, TSG101
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| RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms.
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| Rush JS, Ceresa BP.
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| Mol Cell Endocrinol 381(1-2):188-97. doi: 10.1016/j.mce.2013.07.029. Epub 2013 Aug 7.
2013
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| 7 | ARRDC1, TSG101
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| Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.
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| Nabhan JF, Hu R, Oh RS, Cohen SN, Lu Q.
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| Proc Natl Acad Sci U S A 109(11):4146-51. doi: 10.1073/pnas.1200448109. Epub 2012 Feb 6. 2012
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| 8 | RAB11FIP3, RAB11FIP4, TSG101
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| Tumor susceptibility gene 101 (TSG101) is a novel binding-partner for the class II Rab11-FIPs.
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| Horgan CP, Hanscom SR, Kelly EE, McCaffrey MW.
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| PLoS One 7(2):e32030. doi: 10.1371/journal.pone.0032030. Epub 2012 Feb 14.
2012
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| 9 | CMT1C, HGS, LITAF, STAM, TSG101
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| Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking.
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| Lee SM, Chin LS, Li L.
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| J Cell Biol 199(5):799-816. doi: 10.1083/jcb.201204137. Epub 2012 Nov 19.
2012
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| 10 | TSG101, UBAP1, VPS28, VPS37A
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| The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
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| Agromayor M, Soler N, Caballe A, Kueck T, Freund SM, Allen MD, Bycroft M, Perisic O, Ye Y, McDonald B, Scheel H, Hofmann K, Neil SJ, Martin-Serrano J, Williams RL.
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| Structure 20(3):414-28. doi: 10.1016/j.str.2011.12.013.
2012
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| 11 | PEG10, TSG101
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| Identification of PEG10 and TSG101 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma.
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| Liu DC, Yang ZL, Jiang S.
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| Pathol Oncol Res 17(4):859-66. doi: 10.1007/s12253-011-9394-7. Epub 2011 Apr 1.
2011
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| 12 | TSG101
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| Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway.
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| Zhang Y, Song M, Cui ZS, Li CY, Xue XX, Yu M, Lu Y, Zhang SY, Wang EH, Wen YY.
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| Histol Histopathol 26(1):87-94.
2011
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| 13 | TSG101
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| Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles.
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| Dolnik O, Kolesnikova L, Stevermann L, Becker S.
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| J Virol 84(15):7847-56. doi: 10.1128/JVI.00476-10. Epub 2010 May 26.
2010
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| 14 | TSG101
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| TSG101: a novel anti-HIV-1 drug target.
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| Chen H, Liu X, Li Z, Zhan P, De Clercq E.
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| Curr Med Chem 17(8):750-8. Review.
2010
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| 15 | ALG2, PDCD6, PDCD6IP, TSG101
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| Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
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| Okumura M, Ichioka F, Kobayashi R, Suzuki H, Yoshida H, Shibata H, Maki M.
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| Biochem Biophys Res Commun 386(1):237-41. Epub 2009 Jun 9. 2009
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| 16 | TSG101
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| Genetic analysis of ESCRT function in Drosophila: a tumour model for human Tsg101.
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| Herz HM, Bergmann A.
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| Biochem Soc Trans 37(Pt 1):204-7. Review.
2009
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| 17 | TSG101
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| Overexpression of WNT2 and TSG101 genes in colorectal carcinoma.
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| Ma XR, Edmund Sim UH, Pauline B, Patricia L, Rahman J.
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| Trop Biomed 25(1):46-57.
2008
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| 18 | LRSAM1, TSG101
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| Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase.
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| McDonald B, Martin-Serrano J.
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| Mol Biol Cell ol Biol Cell. 2008
2008
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| 19 | PDCD6IP, CEP55, TSG101, ROCK1, IQGAP1, CD2AP
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| Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.
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| Morita E, Sandrin V, Chung HY, Morham SG, Gygi SP, Rodesch CK, Sundquist WI.
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| EMBO J 26(19):4215-27. Epub 2007 Sep 13. 2007
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| 20 | RNF103-CHMP3, TSG101
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| The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.
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| Bache KG, Stuffers S, Malerod L, Slagsvold T, Raiborg C, Lechardeur D, Walchli S, Lukacs GL, Brech A, Stenmark H.
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| Mol Biol Cell 17(6):2513-23. Epub 2006 Mar 22. 2006
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| 21 | SNX1, HARS, TSG101
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| An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins.
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| Gullapalli A, Wolfe BL, Griffin CT, Magnuson T, Trejo J.
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| Mol Biol Cell 17(3):1228-38. Epub 2006 Jan 11. 2006
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| 22 | RNF103-CHMP3, TSG101, VPS28
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| Structure of the ESCRT-II endosomal trafficking complex.
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| Hierro A, Sun J, Rusnak AS, Kim J, Prag G, Emr SD, Hurley JH.
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| Nature 431(7005):221-5. Epub 2004 Aug 25. 2004
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| 23 | TSG101, DAXX, DMAP1
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| Physical and functional interactions between Daxx and TSG101.
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| Muromoto R, Sugiyama K, Yamamoto T, Oritani K, Shimoda K, Matsuda T.
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| Biochem Biophys Res Commun 316(3):827-33. 2004
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| 24 | TSG101, AATF
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| TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination.
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| Burgdorf S, Leister P, Scheidtmann KH.
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| J Biol Chem 279(17):17524-34. Epub 2004 Feb 2. 2004
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| 25 | LRSAM1, TSG101
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| Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.
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| Amit I, Yakir L, Katz M, Zwang Y, Marmor MD, Citri A, Shtiegman K, Alroy I, Tuvia S, Reiss Y, Roubini E, Cohen M, Wides R, Bacharach E, Schubert U, Yarden Y.
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| Genes Dev 18(14):1737-52.
2004
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| 26 | TSG101
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| Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas.
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| Liu RT, Huang CC, You HL, Chou FF, Hu CC, Chao FP, Chen CM, Cheng JT.
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| Oncogene 21(31):4830-7. 2002
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| 27 | TSG101
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| Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death.
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| Krempler A, Henry MD, Triplett AA, Wagner KU.
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| J Biol Chem 277(45):43216-23. Epub 2002 Aug 29. 2002
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| 28 | TSG101
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| Clinical implications of aberrant TSG101 transcripts in acute myeloblastic leukemia.
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| Lin SF, Lin PM, Liu TC, Chang JG, Sue YC, Chen TP.
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| Leuk Lymphoma 36(5-6):463-6. 2000
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| 29 | TSG101
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| Analysis of TSG101 tumour susceptibility gene transcripts in cervical and endometrial cancers.
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| Chang JG, et al.
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| Br J Cancer 79(3-4):445-50. 1999
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| 30 | TSG101
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| Expression of a new isoform of the tumor susceptibility TSG101 protein lacking a leucine zipper domain in Burkitt lymphoma cell lines.
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| Ferrer M, et al.
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| Oncogene 18(13):2253-9. 1999
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| 31 | RPL13, FN1, TSG101, UBE2V1
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| Differentially expressed genes in hormone refractory prostate cancer: association with chromosomal regions involved with genetic aberrations.
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| Stubbs AP, et al.
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| Am J Pathol 154(5):1335-43. 1999
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| 32 | TSG101
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| Low frequency of TSG101/CC2 gene alterations in invasive human breast cancers.
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| Wang Q, et al.
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| Oncogene 16 : 677-679. 1998
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| 33 | TSG101
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| A putative tumor suppressor, TSG101, acts as a transcriptional suppressor through its coiled-coil domain.
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| Watanabe M, et al.
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| Biochem Biophys Res Commun 245 : 900-905. 1998
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| 34 | TSG101
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| Aberrant TSG101 transcripts in acute myeloid leukaemia.
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| Lin PM, et al.
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| Br J haematol 102 : 753-758. 1998
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| 35 | TSG101
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| TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer.
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| Oh Y, et al.
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| Oncogene 17 : 1141-1148. 1998
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| 36 | TSG101
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| Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101 : common types of shorter transcripts are true alternative splice variants.
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| Wagner KU, et al.
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| Oncogene 17 : 2761-2770. 1998
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| 37 | ST5, TSG101
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| The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer.(see retractation Cell 93 : 661. 1998)
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| Li L, et al.
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| Cell 88 : 143-154. 1997
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| 38 | TSG101
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| TSG101 may be the prototype of a class of dominant negative ubiquitin regulators.
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| Koonin EV, Abagyan RA.
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| Nat Genet 16(4):330-1. 1997
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| 39 | TSG101
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| Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer.
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| Steiner P, Barnes DM, Harris WH, Weinberg RA.
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| Nat Genet 16(4):332-3. 1997
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| 40 | FHIT, TSG101
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| Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours.
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| Gayther SA, Barski P, Batley SJ, Li L, de Foy KA, Cohen SN, Ponder BA, Caldas C.
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| Oncogene 15(17):2119-26. 1997
|