| 1 | TRRAP, TRRAPD
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| Missense Variants in the Histone Acetyltransferase Complex Component Gene TRRAP Cause Autism and Syndromic Intellectual Disability.
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| Cogné B, Ehresmann S, Beauregard-Lacroix E, Rousseau J, Besnard T, Garcia T, Petrovski S, Avni S, McWalter K, Blackburn PR, Sanders SJ, Uguen K, Harris J, Cohen JS, Blyth M, Lehman A, Berg J, Li MH, Kini U, Joss S, von der Lippe C, Gordon CT, Humberson JB, Robak L, Scott DA, Sutton VR, Skraban CM, Johnston JJ, Poduri A, Nordenskjöld M, Shashi V, Gerkes EH, Bongers EMHF, Gilissen C, Zarate YA, Kvarnung M, Lally KP, Kulch PA, Daniels B, Hernandez-Garcia A, Stong N, McGaughran J, Retterer K, Tveten K, Sullivan J, Geisheker MR, Stray-Pedersen A, Tarpinian JM, Klee EW, Sapp JC, Zyskind J, Holla ØL, Bedoukian E, Filippini F, Guimier A, Picard A, Busk ØL, Punetha J, Pfundt R, Lindstrand A, Nordgren A, Kalb F, Desai M, Ebanks AH, Jhangiani SN, Dewan T, Coban Akdemir ZH, Telegrafi A, Zackai EH, Begtrup A, Song X, Toutain A, Wentzensen IM, Odent S, Bonneau D, Latypova X, Deb W; CAUSES Study, Redon S, Bilan F, Legendre M, Troyer C, Whitlock K, Caluseriu O, Murphree MI, Pichurin PN, Agre K, Gavrilova R, Rinne T, Park M, Shain C, Heinzen EL, Xiao R, Amiel J, Lyonnet S, Isidor B, Biesecker LG, Lowenstein D, Posey JE, Denommé-Pichon AS; Deciphering Developmental Disorders study, Férec C, Yang XJ, Rosenfeld JA, Gilbert-Dussardier B, Audebert-Bellanger S, Redon R, Stessman HAF, Nellaker C, Yang Y, Lupski JR, Goldstein DB, Eichler EE, Bolduc F, Bézieau S, Küry S, Campeau PM.
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| Am J Hum Genet 104(3):530-541. doi: 10.1016/j.ajhg.2019.01.010. Epub 2019 Feb 28.
2019
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| 2 | TRRAP
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| De novo variant of TRRAP in a patient with very early onset psychosis in the context of non-verbal learning disability and obsessive-compulsive disorder: a case report.
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| Mavros CF, Brownstein CA, Thyagrajan R, Genetti CA, Tembulkar S, Graber K, Murphy Q, Cabral K, VanNoy GE, Bainbridge M, Shi J, Agrawal PB, Beggs AH, D'Angelo E, Gonzalez-Heydrich J.
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| BMC Med Genet 19(1):197. doi: 10.1186/s12881-018-0711-9.
2018
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| 3 | TRRAP
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| TRRAP stimulates the tumorigenic potential of ovarian cancer stem cells.
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| Kang KT, Kwon YW, Kim DK, Lee SI, Kim KH, Suh DS, Kim JH.
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| BMB Rep 51(10):514-519.
2018
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| 4 | TRRAP
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| TRRAP is a central regulator of human multiciliated cell formation.
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| Wang Z, Plasschaert LW, Aryal S, Renaud NA, Yang Z, Choo-Wing R, Pessotti AD, Kirkpatrick ND, Cochran NR, Carbone W, Maher R, Lindeman A, Russ C, Reece-Hoyes J, McAllister G, Hoffman GR, Roma G, Jaffe AB.
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| J Cell Biol 217(6):1941-1955. doi: 10.1083/jcb.201706106. Epub 2018 Mar 27.
2018
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| 5 | TRRAP, USP7
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| HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.
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| Bhattacharya S, Ghosh MK.
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| Cell Oncol (Dordr) 38(4):265-77. doi: 10.1007/s13402-015-0228-6. Epub 2015 Apr 30.
2015
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| 6 | KAT2A, MYC, TRRAP
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| MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits.
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| Zhang N, Ichikawa W, Faiola F, Lo SY, Liu X, Martinez E.
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| Biochim Biophys Acta 1839(5):395-405. doi: 10.1016/j.bbagrm.2014.03.017. Epub 2014 Apr 3.
2014
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| 7 | TRRAP
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| Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.
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| Leduc C, Chemin G, Puget N, Sawan C, Moutahir M, Herceg Z, Khamlichi AA.
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| Cell Cycle 13(10):1583-9. doi: 10.4161/cc.28560. Epub 2014 Mar 18.
2014
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| 8 | TRRAP
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| The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.
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| Ichim G, Mola M, Finkbeiner MG, Cros MP, Herceg Z, Hernandez-Vargas H.
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| Oncogene 33(2):181-92. doi: 10.1038/onc.2012.570. Epub 2013 Jan 14.
2014
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| 9 | TRRAP
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| Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells.
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| Sawan C, Hernandez-Vargas H, Murr R, Lopez F, Vaissière T, Ghantous AY, Cuenin C, Imbert J, Wang ZQ, Ren B, Herceg Z.
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| Stem Cells 31(5):979-91. doi: 10.1002/stem.1341.
2013
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| 10 | GRIN2A, TRRAP
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| Exome sequencing identifies GRIN2A as frequently mutated in melanoma.
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| Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S; NISC Comparative Sequencing Program, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y.
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| Nat Genet 43(5):442-6. Epub 2011 Apr 15.
2011
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| 11 | MYC, RPL11, TRRAP
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| Ribosomal protein L11 associates with c-Myc at 5 S rRNA and tRNA genes and regulates their expression.
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| Dai MS, Sun XX, Lu H.
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| J Biol Chem 285(17):12587-94. Epub 2010 Mar 1.
2010
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| 12 | TRRAP
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| An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
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| Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, Miraglia LJ, Rines DR, Skirboll SL, Schultz PG.
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| Cell Stem Cell 6(1):37-47.
2010
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| 13 | TRRAP
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| Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool.
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| Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, Trumpp A, Herceg Z.
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| J Immunol 183(10):6422-31. Epub 2009 Oct 30.
2009
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| 14 | INTS1, MTREX, TRRAP
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| Ethylnitrosourea-induced thymus-defective mutants identify roles of KIAA1440, TRRAP, and SKIV2L2 in teleost organ development.
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| Iwanami N, Okada M, Hoa VQ, Seo Y, Mitani H, Sasaki T, Shimizu N, Kondoh H, Furutani-Seiki M, Takahama Y.
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| Eur J Immunol 39(9):2606-16. doi: 10.1002/eji.200939362. 2009
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| 15 | KAT5, NPAT, TRRAP
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| Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.
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| DeRan M, Pulvino M, Greene E, Su C, Zhao J.
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| Mol Cell Biol 28(1):435-47. Epub 2007 Oct 29.
2008
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| 16 | TRRAP
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| HAT cofactor TRRAP mediates beta-catenin ubiquitination on the chromatin and the regulation of the canonical Wnt pathway.
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| Finkbeiner MG, Sawan C, Ouzounova M, Murr R, Herceg Z.
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| Cell Cycle 7(24):3908-14. Epub 2008 Dec 6.
2008
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| 17 | KAT2A, TRRAP
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| TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription.
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| Kenneth NS, Ramsbottom BA, Gomez-Roman N, Marshall L, Cole PA, White RJ.
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| Proc Natl Acad Sci U S A 104(38):14917-22. Epub 2007 Sep 11. 2007
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| 18 | TRRAP
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| Orchestration of chromatin-based processes: mind the TRRAP.
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| Murr R, Vaissière T, Sawan C, Shukla V, Herceg Z.
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| Oncogene 26(37):5358-72. Review.
2007
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| 19 | KAT5, MRGBP, SRCAP, TRRAP, VPS72
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| The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.
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| Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW.
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| J Biol Chem 280(14):13665-70. Epub 2005 Jan 11. 2005
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| 20 | E2F1, TRRAP
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| The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins.
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| McMahon SB, Van Buskirk HA, Dugan KA, Copeland TD, Cole MD.
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| Cell. 94(3):363-74. 1998
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| 21 | PPP1R7, TRRAP, SETMAR
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| Gene-based sequence-tagged-sites (STSs) as the basis for a human gene map.
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| Berry R, Stevens TJ, Walter NA, Wilcox AS, Rubano T, Hopkins JA, Weber J,Goold R, Soares MB, Sikela JM.
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| Nat Genet 10(4):415-23. 1995
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