Citations for
1TRPC3
Pharmacological evidence for a role of the transient receptor potential canonical 3 (TRPC3) channel in endoplasmic reticulum stress-induced apoptosis of human coronary artery endothelial cells.
Ampem PT, Smedlund K, Vazquez G.
Vascul Pharmacol ascul Pharmacol. 2015 Jul 26. pii: S1537-1891(15)00170-6. doi: 10.1016/j.vph.2015.07.011. [Epub ahead of print] 2015
2SYPL2, TRPC3, TRPC4
Interaction between mitsugumin 29 and TRPC3 participates in regulating Ca(2+) transients in skeletal muscle.
Woo JS, Hwang JH, Huang M, Ahn MK, Cho CH, Ma J, Lee EH.
Biochem Biophys Res Commun 464(1):133-9. doi: 10.1016/j.bbrc.2015.06.096. Epub 2015 Jun 30. 2015
3TRPC3
Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse.
Hanson SM, Sansom MS, Becker EB.
Biochemistry 54(26):4033-41. doi: 10.1021/acs.biochem.5b00235. Epub 2015 Jun 26. 2015
4TRPC3
Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation.
Ishise H, Larson B, Hirata Y, Fujiwara T, Nishimoto S, Kubo T, Matsuda K, Kanazawa S, Sotsuka Y, Fujita K, Kakibuchi M, Kawai K.
Sci Rep 5:11620. doi: 10.1038/srep11620. 2015
5TRPC3
TRPC3-dependent synaptic transmission in central mammalian neurons.
Hartmann J, Konnerth A.
J Mol Med (Berl) Mol Med (Berl). 2015 Jun 5. [Epub ahead of print] 2015
6TRPC3
The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum.
Dulneva A, Lee S, Oliver PL, Di Gleria K, Kessler BM, Davies KE, Becker EB.
Hum Mol Genet 24(14):4114-25. doi: 10.1093/hmg/ddv150. Epub 2015 Apr 23. 2015
7TRPC3
Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages.
Solanki S, Dube PR, Tano JY, Birnbaumer L, Vazquez G.
Am J Physiol Cell Physiol 307(6):C521-31. doi: 10.1152/ajpcell.00369.2013. Epub 2014 Jul 16. 2014
8TRPC1, TRPC3
Heteromeric TRPC3 with TRPC1 formed via its ankyrin repeats regulates the resting cytosolic Ca2+ levels in skeletal muscle.
Woo JS, Lee KJ, Huang M, Cho CH, Lee EH.
Biochem Biophys Res Commun 446(2):454-9. doi: 10.1016/j.bbrc.2014.02.127. Epub 2014 Mar 5. 2014
9TRPC3, TRPM2
Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder.
Roedding AS, Tong SY, Au-Yeung W, Li PP, Warsh JJ.
Brain Res 1517:16-27. doi: 10.1016/j.brainres.2013.04.025. Epub 2013 Apr 18. 2013
10TRPC3
TRPC3 regulates release of brain-derived neurotrophic factor from human airway smooth muscle.
Vohra PK, Thompson MA, Sathish V, Kiel A, Jerde C, Pabelick CM, Singh BB, Prakash YS.
Biochim Biophys Acta 1833(12):2953-60. doi: 10.1016/j.bbamcr.2013.07.019. Epub 2013 Jul 27. 2013
11TRPC3
Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake.
Feng S, Li H, Tai Y, Huang J, Su Y, Abramowitz J, Zhu MX, Birnbaumer L, Wang Y.
Proc Natl Acad Sci U S A 110(27):11011-6. doi: 10.1073/pnas.1309531110. Epub 2013 Jun 17. 2013
12ADORA1, TRPC3
Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction.
Sabourin J, Antigny F, Robin E, Frieden M, Raddatz E.
J Biol Chem 287(32):26688-701. doi: 10.1074/jbc.M112.378588. Epub 2012 Jun 12. 2012
13TRPC3
Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation.
Harada M, Luo X, Qi XY, Tadevosyan A, Maguy A, Ordog B, Ledoux J, Kato T, Naud P, Voigt N, Shi Y, Kamiya K, Murohara T, Kodama I, Tardif JC, Schotten U, Van Wagoner DR, Dobrev D, Nattel S.
Circulation 126(17):2051-64. doi: 10.1161/CIRCULATIONAHA.112.121830. Epub 2012 Sep 19. 2012
14TRPC3, TRPC6
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.
Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, Richardson GP, Freichel M, Flockerzi V, Birnbaumer L, Wood JN.
Open Biol 2(5):120068. doi: 10.1098/rsob.120068. 2012
15TRPC3
Williams-Beuren syndrome hypercalcemia: is TRPC3 a novel mediator in calcium homeostasis?
Letavernier E, Rodenas A, Guerrot D, Haymann JP.
Pediatrics 129(6):e1626-30. doi: 10.1542/peds.2011-2507. Epub 2012 May 7. 2012
16TRPC3
Candidate screening of the TRPC3 gene in cerebellar ataxia.
Becker EB, Fogel BL, Rajakulendran S, Dulneva A, Hanna MG, Perlman SL, Geschwind DH, Davies KE.
Cerebellum 10(2):296-9. doi: 10.1007/s12311-011-0253-6. 2011
17TRPC3
The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin.
Hirschler-Laszkiewicz I, Tong Q, Waybill K, Conrad K, Keefer K, Zhang W, Chen SJ, Cheung JY, Miller BA.
J Biol Chem 286(35):30636-46. doi: 10.1074/jbc.M111.238360. Epub 2011 Jul 14. 2011
18ORAI1, RACK1, TRPC3
TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1.
Woodard GE, López JJ, Jardín I, Salido GM, Rosado JA.
J Biol Chem 285(11):8045-53. Epub 2009 Dec 18.PMID: 20022948 2010
19TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, TRPC7
TRPC channels are necessary mediators of pathologic cardiac hypertrophy.
Wu X, Eder P, Chang B, Molkentin JD.
Proc Natl Acad Sci U S A. 107(15):7000-5. 2010
20TRPC3, TRPC6
TRPC3 activation by erythropoietin is modulated by TRPC6.
Hirschler-Laszkiewicz I, Tong Q, Conrad K, Zhang W, Flint WW, Barber AJ, Barber DL, Cheung JY, Miller BA.
J Biol Chem 284(7):4567-81. Epub 2008 Dec 13. 2009
21PKD2, TRPC3, TRPC7
A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.
Miyagi K, Kiyonaka S, Yamada K, Miki T, Mori E, Kato K, Numata T, Sawaguchi Y, Numaga T, Kimura T, Kanai Y, Kawano M, Wakamori M, Nomura H, Koni I, Yamagishi M, Mori Y.
J Biol Chem 284(49):34400-12. Epub 2009 Oct 7.PMID: 19812035 2009
22TRPC3
Regulation of cardiac hypertrophy by the formation of G protein-coupled receptor--TRPC channel protein complex.
Nishida M, Sato Y, Nakaya M, Kurose H.
Nippon Yakurigaku Zasshi 134(3):131-6. Review. No abstract available. 2009
23TRPC3
Enhanced expression of STIM1/Orai1 and TRPC3 in platelets from patients with type 2 diabetes mellitus.
Zbidi H, López JJ, Amor NB, Bartegi A, Salido GM, Rosado JA.
Blood Cells Mol Dis 43(2):211-3. Epub 2009 May 17. 2009
24SCA41, TRPC3
A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice.
Becker EB, Oliver PL, Glitsch MD, Banks GT, Achilli F, Hardy A, Nolan PM, Fisher EM, Davies KE.
Proc Natl Acad Sci U S A 106(16):6706-11. doi: 10.1073/pnas.0810599106. Epub 2009 Apr 7. 2009
25TRPM4, TRPC3
TRPM4b channel suppresses store-operated Ca2+ entry by a novel protein-protein interaction with the TRPC3 channel.
Park JY, Hwang EM, Yarishkin O, Seo JH, Kim E, Yoo J, Yi GS, Kim DG, Park N, Ha CM, La JH, Kang D, Han J, Oh U, Hong SG.
Biochem Biophys Res Commun 368(3):677-83. Epub 2008 Feb 8. 2008
26EPO, TRPC3
TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells.
Tong Q, Hirschler-Laszkiewicz I, Zhang W, Conrad K, Neagley DW, Barber DL, Cheung JY, Miller BA.
J Biol Chem 283(16):10385-95. Epub 2008 Feb 14. 2008
27RYR1, TRPC3
TRPC3-interacting triadic proteins in skeletal muscle.
Woo JS, Kim do H, Allen PD, Lee EH.
Biochem J 411(2):399-405.PMID: 18215135 2008
28TRPC3, TRPC7
Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion.
Lavender V, Chong S, Ralphs K, Wolstenholme AJ, Reaves BJ.
Biochem J 413(3):437-46. 2008
29TRPC3,TRPC6
TRPC channels promote cerebellar granule neuron survival.
Jia Y, Zhou J, Tai Y, Wang Y.
Nat Neurosci 10(5):559-67. Epub 2007 Apr 1. 2007
30TRPC3
Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel.
Yildirim E, Kawasaki BT, Birnbaumer L.
Proc Natl Acad Sci U S A 102(9):3307-11. Epub 2005 Feb 22. 2005
31TRPC1, TRPC2, TRPC3, TRPC4, TRPC6, TRPC7
Transient receptor potential (TRPC) channels in human sperm: expression, cellular localization and involvement in the regulation of flagellar motility.
Castellano LE, Trevino CL, Rodriguez D, Serrano CJ, Pacheco J, Tsutsumi V, Felix R, Darszon A.
FEBS Lett 541(1-3):69-74. 2003
32TRPC3, TRPC6
TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes.
Philipp S, Strauss B, Hirnet D, Wissenbach U, Mery L, Flockerzi V, Hoth M.
J Biol Chem 278(29):26629-38. Epub 2003 May 6. 2003
33TRPC3, TRPC6
N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.
Dietrich A, Mederos y Schnitzler M, Emmel J, Kalwa H, Hofmann T, Gudermann T.
J Biol Chem 278(48):47842-52. Epub 2003 Sep 11. 2003
34TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, TRPM2
From worm to man: three subfamilies of TRP channels.
Harteneck C, Plant TD, Schultz G.
Trends Neurosci 23(4):159-66. Review. 2000
35TRPC3, TRPC4
Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3.
McKay RR, Szymeczek-Seay CL, Lievremont JP, Bird GS, Zitt C, Jungling E, Luckhoff A, Putney JW Jr.
Biochem J 351 Pt 3:735-46. 2000
36TRPC3, TRPC6
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.
Hofmann T, Obukhov AG, Schaefer M, Harteneck C, Gudermann T, Schultz G.
Nature 397(6716):259-63. 1999
37TRPC3
Expression of human TRPC genes in the megakaryocytic cell lines MEG01, DAMI and HEL.
Berg LP, Shamsher MK, El-Daher SS, Kakkar VV, Authi KS.
FEBS Lett 403(1):83-6. 1997
38TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, TRPM2
trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.
Zhu X, Jiang M, Peyton M, Boulay G, Hurst R, Stefani E, Birnbaumer L.
Cell 85(5):661-71. 1996