| 1 | BTRC, RFWD2, SMURF1, TRIB2
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| TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells.
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| Xu S, Tong M, Huang J, Zhang Y, Qiao Y, Weng W, Liu W, Wang J, Sun F.
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| FEBS Lett 588(23):4334-41. doi: 10.1016/j.febslet.2014.09.042. Epub 2014 Oct 13.
2014
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| 2 | TRIB2
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| Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα.
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| Grandinetti KB, Stevens TA, Ha S, Salamone RJ, Walker JR, Zhang J, Agarwalla S, Tenen DG, Peters EC, Reddy VA.
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| Oncogene 30(30):3328-35. doi: 10.1038/onc.2011.57. Epub 2011 Mar 14.
2011
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| 3 | TRIB2
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| Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells.
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| Zanella F, Renner O, García B, Callejas S, Dopazo A, Peregrina S, Carnero A, Link W.
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| Oncogene 29(20):2973-82. Epub 2010 Mar 8.
2010
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| 4 | RFWD2, TRIB2
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| Transformation by Tribbles homologue 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.
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| Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS.
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| Blood lood. 2010 Aug 31. [Epub ahead of print]PMID: 20805362 2010
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| 5 | TRIB2
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| Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.
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| Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS.
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| Blood 116(23):4948-57. Epub 2010 Aug 30. 2010
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| 6 | TRIB1, TRIB2
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| Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia.
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| Gilby DC, Sung HY, Winship PR, Goodeve AC, Reilly JT, Kiss-Toth E.
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| Immunol Lett 130(1-2):115-24. doi: 10.1016/j.imlet.2009.12.007. Epub 2009 Dec 11.
2010
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| 7 | TRIB2
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| Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro.
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| Deng J, James CH, Patel L, Smith A, Burnand KG, Rahmoune H, Lamb JR, Davis B.
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| Clin Sci (Lond) 116(3):241-8. 2009
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| 8 | TRIB2
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| Tribbles-2 is a novel regulator of inflammatory activation of monocytes.
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| Eder K, Guan H, Sung HY, Ward J, Angyal A, Janas M, Sarmay G, Duda E, Turner M, Dower SK, Francis SE, Crossman DC, Kiss-Toth E.
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| Int Immunol 20(12):1543-50. Epub 2008 Oct 24.
2008
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| 9 | TRIB2
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| Tribbles: a family of kinase-like proteins with potent signalling regulatory function.
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| Hegedus Z, Czibula A, Kiss-Toth E.
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| Cell Signal 19(2):238-50. Epub 2006 Sep 11. Review.
2007
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| 10 | TRIB2
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| Identification of tribbles homolog 2 as an autoantigen in autoimmune uveitis by phage display.
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| Zhang Y, Davis JL, Li W.
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| Mol Immunol 42(11):1275-81. Epub 2005 Feb 8. 2005
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| 11 | TRIB1, TRIB2, TRIB3
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| Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
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| Kiss-Toth E, Bagstaff SM, Sung HY, Jozsa V, Dempsey C, Caunt JC, Oxley KM, Wyllie DH, Polgar T, Harte M, O'neill LA, Qwarnstrom EE, Dower SK.
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| J Biol Chem 279(41):42703-8. Epub 2004 Aug 6. 2004
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| 12 | TRIB1, TRIB2
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| Characterization of a phosphoprotein whose mRNA is regulated by the mitogenic pathways in dog thyroid cells.
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| Wilkin F, Suarez-Huerta N, Robaye B, Peetermans J, Libert F, Dumont JE,Maenhaut C.
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| Eur J Biochem 248(3):660-8. 1997
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