| 1 | TMUB1, TRAF6
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| HOPS/Tmub1 involvement in the NF-kB-mediated inflammatory response through the modulation of TRAF6
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| Bellet MM, Pieroni S, Castelli M, Piobbico D, Fallarino F, Romani L, Della-Fazia MA, Servillo G.
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| Cell Death Dis. Oct 15;11(10):865. doi: 10.1038/s41419-020-03086-5 2020
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| 2 | METTL3, TRAF6
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| Mettl3 Deficiency Sustains Long-Chain Fatty Acid Absorption through Suppressing Traf6-Dependent Inflammation Response.
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| Zong X, Zhao J, Wang H, Lu Z, Wang F, Du H, Wang Y.
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| J Immunol 202(2):567-578. doi: 10.4049/jimmunol.1801151. Epub 2018 Dec 19.
2019
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| 3 | TNFSF13B, TRAF1, TRAF2, TRAF3, TRAF6, TRAF7
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| Roles of TRAFs in NF-κB signaling pathways mediated by BAFF.
|
| Tang X, Zhang L, Wei W.
|
| Immunol Lett 196:113-118. doi: 10.1016/j.imlet.2018.01.010. Epub 2018 Feb 20. Review.
2018
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| 4 | BCL3, TNFSF11, TRAF6
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| BCL3 regulates RANKL-induced osteoclastogenesis by interacting with TRAF6 in bone marrow-derived macrophages.
|
| Wang K, Li S, Gao Y, Feng X, Liu W, Luo R, Song Y, Ji Tu, Liu Y, Yang C
|
| Bone. Sep;114:257-267. doi: 10.1016/j.bone.2018.06.015. Epub 2018 Jun 19. 2018
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| 5 | TRAF6, YOD1
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| YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB.
|
| Schimmack G, Schorpp K, Kutzner K, Gehring T, Brenke JK, Hadian K, Krappmann D.
|
| Elife 6. pii: e22416. doi: 10.7554/eLife.22416.
2017
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| 6 | TNFRSF11A, TRAF6, VAV3
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| Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.
|
| Yu J, Yun H, Shin B, Kim Y, Park ES, Choi S, Yu J, Amarasekara DS, Kim S, Inoue J, Walsh MC, Choi Y, Takami M, Rho J.
|
| J Biol Chem 291(39):20643-60. doi: 10.1074/jbc.M116.728303. Epub 2016 Aug 9.
2016
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| 7 | BSG, TRAF6
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| TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin.
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| Luo Z, Zhang X, Zeng W, Su J, Yang K, Lu L, Lim CB, Tang W, Wu L, Zhao S, Jia X, Peng C, Chen X.
|
| Oncotarget 7(6):7179-92. doi: 10.18632/oncotarget.6886.
2016
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| 8 | TANK, USP10, ZC3H12A, tRAF6
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| TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
|
| Wang W, Huang X, Xin HB, Fu M, Xue A, Wu ZH.
|
| J Biol Chem 290(21):13372-85. doi: 10.1074/jbc.M115.643767. Epub 2015 Apr 10.
2015
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| 9 | CD40, SQSTM1, TRAF6
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| p62 regulates CD40-mediated NFκB activation in macrophages through interaction with TRAF6.
|
| Seibold K, Ehrenschwender M.
|
| Biochem Biophys Res Commun 464(1):330-5. doi: 10.1016/j.bbrc.2015.06.153. Epub 2015 Jun 29.
2015
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| 10 | DOK3, TLR9, TRAF6
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| TRAF6-mediated degradation of DOK3 is required for production of IL-6 and TNFα in TLR9 signaling.
|
| Liu N, Tang B, Wei P, Sun W, Wang S, Peng Q.
|
| Mol Immunol 68(2 Pt C):699-705. doi: 10.1016/j.molimm.2015.10.021. Epub 2015 Nov 6.
2015
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| 11 | CSF2, TRAF6
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| TRAF6 is required for the GM-CSF-induced JNK, p38 and Akt activation.
|
| Wang Y, Zhou C, Huo J, Ni Y, Zhang P, Lu C, Jing B, Xiao F, Chen W, Li W, Zhang P, Zhang L.
|
| Mol Immunol 65(2):224-9. doi: 10.1016/j.molimm.2015.01.012. Epub 2015 Feb 17.
2015
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| 12 | MYD88, PPP1CC, TRAF6
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| Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.
|
| Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK.
|
| PLoS One 9(2):e89284. doi: 10.1371/journal.pone.0089284. eCollection 2014.
2014
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| 13 | PLEKHO1, TRAF6
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| CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation.
|
| Zhang L, Wang Y, Xiao F, Wang S, Xing G, Li Y, Yin X, Lu K, Wei R, Fan J, Chen Y, Li T, Xie P, Yuan L, Song L, Ma L, Ding L, He F, Zhang L.
|
| Cell Res 24(6):742-61. doi: 10.1038/cr.2014.53. Epub 2014 Apr 29.
2014
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| 14 | TAB2, TAF5, TRAF6
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| TRAF5 negatively regulates TLR signaling in B lymphocytes.
|
| Buchta CM, Bishop GA.
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| J Immunol 192(1):145-50. doi: 10.4049/jimmunol.1301901. Epub 2013 Nov 20.
2014
|
| 15 | TICAM2, TRAF6
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| The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
|
| Verstak B, Stack J, Ve T, Mangan M, Hjerrild K, Jeon J, Stahl R, Latz E, Gay N, Kobe B, Bowie AG, Mansell A.
|
| J Leukoc Biol 96(3):427-36. doi: 10.1189/jlb.2A0913-487R. Epub 2014 May 8.
2014
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| 16 | TRAF6
|
| Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.
|
| Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, Wu GD, Choi Y.
|
| Immunity 38(6):1211-22. doi: 10.1016/j.immuni.2013.05.012. Epub 2013 Jun 20.
2013
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| 17 | TRAF6, WWP1
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| WW domain containing E3 ubiquitin protein ligase 1 (WWP1) negatively regulates TLR4-mediated TNF-α and IL-6 production by proteasomal degradation of TNF receptor associated factor 6 (TRAF6).
|
| Lin XW, Xu WC, Luo JG, Guo XJ, Sun T, Zhao XL, Fu ZJ.
|
| PLoS One 8(6):e67633. doi: 10.1371/journal.pone.0067633. Print 2013.
2013
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| 18 | APPL1, TRAF6
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| TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt.
|
| Cheng KK, Lam KS, Wang Y, Wu D, Zhang M, Wang B, Li X, Hoo RL, Huang Z, Sweeney G, Xu A.
|
| Biochem J 455(2):207-16. doi: 10.1042/BJ20130760.
2013
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| 19 | PINK1, SARM1, TRAF6
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| SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria.
|
| Murata H, Sakaguchi M, Kataoka K, Huh NH.
|
| Mol Biol Cell 24(18):2772-84. doi: 10.1091/mbc.E13-01-0016. Epub 2013 Jul 24.
2013
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| 20 | ITCH, TRAF6
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| Ubiquitin E3 ligase Itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.
|
| Zhang H, Wu C, Matesic LE, Li X, Wang Z, Boyce BF, Xing L.
|
| J Biol Chem 288(31):22359-68. doi: 10.1074/jbc.M112.442459. Epub 2013 Jun 19.
2013
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| 21 | TRAF6
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| TRAF6 upregulates expression of HIF-1α and promotes tumor angiogenesis.
|
| Sun H, Li XB, Meng Y, Fan L, Li M, Fang J.
|
| Cancer Res 73(15):4950-9. doi: 10.1158/0008-5472.CAN-13-0370. Epub 2013 May 30.
2013
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| 22 | TRAF6, UBE2O
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| UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.
|
| Zhang X, Zhang J, Zhang L, van Dam H, ten Dijke P.
|
| Cell Res 23(3):366-77. doi: 10.1038/cr.2013.21. Epub 2013 Feb 5.
2013
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| 23 | TICAM1, TLR9, TRAF6
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| High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.
|
| Volpi C, Fallarino F, Pallotta MT, Bianchi R, Vacca C, Belladonna ML, Orabona C, De Luca A, Boon L, Romani L, Grohmann U, Puccetti P.
|
| Nat Commun 4:1852. doi: 10.1038/ncomms2874.
2013
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| 24 | SMAD6, TNFAIP3, TRAF6
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| Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.
|
| Jung SM, Lee JH, Park J, Oh YS, Lee SK, Park JS, Lee YS, Kim JH, Lee JY, Bae YS, Koo SH, Kim SJ, Park SH.
|
| Nat Commun 4:2562. doi: 10.1038/ncomms3562.
2013
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| 25 | OTUD7B, TRAF6
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| Cezanne paints inflammation by regulating ubiquitination.
|
| Abe J, Berk BC.
|
| Circ Res 112(12):1526-8. doi: 10.1161/CIRCRESAHA.113.301518. No abstract available.
2013
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| 26 | OTUD7B, TRAF6
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| Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination.
|
| Luong le A, Fragiadaki M, Smith J, Boyle J, Lutz J, Dean JL, Harten S, Ashcroft M, Walmsley SR, Haskard DO, Maxwell PH, Walczak H, Pusey C, Evans PC.
|
| Circ Res 112(12):1583-91. doi: 10.1161/CIRCRESAHA.111.300119. Epub 2013 Apr 5.
2013
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| 27 | SIK1, SIK3, TAB2, TLR4, TRAF6
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| Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal.
|
| Yong Kim S, Jeong S, Chah KH, Jung E, Baek KH, Kim ST, Shim JH, Chun E, Lee KY.
|
| Mol Endocrinol 27(11):1958-68. doi: 10.1210/me.2013-1240. Epub 2013 Sep 23. 2013
|
| 28 | KIF23, TRAF6
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| TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy.
|
| Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A.
|
| Autophagy 9(12):1955-64.
2013
|
| 29 | LAT, TRAF6
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| TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapter.
|
| Xie JJ, Liang JQ, Diao LH, Altman A, Li Y.
|
| J Immunol 190(8):4027-36. doi: 10.4049/jimmunol.1202742. Epub 2013 Mar 20.
2013
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| 30 | CASP3, CCND1, MMP9, NUMBL, TRAF6
|
| Numblike regulates proliferation, apoptosis, and invasion of lung cancer cell.
|
| Yingjie L, Jian T, Changhai Y, Jingbo L.
|
| Tumour Biol 34(5):2773-80. doi: 10.1007/s13277-013-0835-7. Epub 2013 May 17.
2013
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| 31 | FHL2, TRAF6
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| LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis
|
| Dahan J, Nouët Y, Jouvion G, Levillayer F, Adib-Conquy M, Cassard-Doulcier AM, Tebbi A, Blanc F, Remy L, Chen J, Cairo S, Werts C, Si-Tahar M, Tordjmann T, Buendia MA, Wei Y.
|
| Mol Cell Biol. Aug;33(16):3299-308. doi: 10.1128/MCB.00105-13. Epub 2013 Jun 17. 2013
|
| 32 | TRAF6, TRIM38
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| E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages.
|
| Zhao W, Wang L, Zhang M, Yuan C, Gao C.
|
| J Immunol 188(6):2567-74. doi: 10.4049/jimmunol.1103255. Epub 2012 Feb 8.
2012
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| 33 | TRAF6
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| TRAF6 inhibits proangiogenic signals in endothelial cells and regulates the expression of vascular endothelial growth factor.
|
| Bruneau S, Datta D, Flaxenburg JA, Pal S, Briscoe DM.
|
| Biochem Biophys Res Commun 419(1):66-71. doi: 10.1016/j.bbrc.2012.01.128. Epub 2012 Feb 2.
2012
|
| 34 | STAT3, TRAF6
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| The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination.
|
| Wei J, Yuan Y, Jin C, Chen H, Leng L, He F, Wang J.
|
| PLoS One 7(11):e49567. doi: 10.1371/journal.pone.0049567. Epub 2012 Nov 19.
2012
|
| 35 | TRAF6
|
| Reciprocal interaction between TRAF6 and notch signaling regulates adult myofiber regeneration upon injury.
|
| Hindi SM, Paul PK, Dahiya S, Mishra V, Bhatnagar S, Kuang S, Choi Y, Kumar A.
|
| Mol Cell Biol 32(23):4833-45. doi: 10.1128/MCB.00717-12. Epub 2012 Oct 1.
2012
|
| 36 | TRAF6
|
| TRAF6 regulates proliferation, apoptosis, and invasion of osteosarcoma cell.
|
| Meng Q, Zheng M, Liu H, Song C, Zhang W, Yan J, Qin L, Liu X.
|
| Mol Cell Biochem 371(1-2):177-86. doi: 10.1007/s11010-012-1434-4. Epub 2012 Aug 12.
2012
|
| 37 | TRAF6
|
| TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation.
|
| Yen ML, Hsu PN, Liao HJ, Lee BH, Tsai HF.
|
| PLoS One 7(6):e38048. doi: 10.1371/journal.pone.0038048. Epub 2012 Jun 14.
2012
|
| 38 | RANBP9, TRAF6
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| The Ran-binding protein RanBPM can depress the NF-κB pathway by interacting with TRAF6.
|
| Wang L, Fu C, Cui Y, Xie Y, Yuan Y, Wang X, Chen H, Huang BR.
|
| Mol Cell Biochem 359(1-2):83-94. doi: 10.1007/s11010-011-1002-3. Epub 2011 Jul 30.
2012
|
| 39 | RNF168, RNF8, STUB1, TRAF6, UBE2N
|
| Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
|
| Campbell SJ, Edwards RA, Leung CC, Neculai D, Hodge CD, Dhe-Paganon S, Glover JN.
|
| J Biol Chem 287(28):23900-10. doi: 10.1074/jbc.M112.359653. Epub 2012 May 15.
2012
|
| 40 | TRAF6
|
| TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.
|
| Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE.
|
| J Biol Chem 287(20):16132-45. doi: 10.1074/jbc.M111.310102. Epub 2012 Mar 23.
2012
|
| 41 | IL17A, TBK1, TRAF3IP2, TRAF6
|
| TRAF6-dependent Act1 phosphorylation by the IκB kinase-related kinases suppresses interleukin-17-induced NF-κB activation.
|
| Qu F, Gao H, Zhu S, Shi P, Zhang Y, Liu Y, Jallal B, Yao Y, Shi Y, Qian Y.
|
| Mol Cell Biol 32(19):3925-37. doi: 10.1128/MCB.00268-12. Epub 2012 Jul 30.
2012
|
| 42 | IL17A, TRAF3IP2, TRAF6
|
| IL-17-induced NF-kappaB activation via CIKS/Act1: physiologic significance and signaling mechanisms.
|
| Sønder SU, Saret S, Tang W, Sturdevant DE, Porcella SF, Siebenlist U.
|
| J Biol Chem 286(15):12881-90. Epub 2011 Feb 18.
2011
|
| 43 | HTT, TRAF6
|
| Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.
|
| Zucchelli S, Marcuzzi F, Codrich M, Agostoni E, Vilotti S, Biagioli M, Pinto M, Carnemolla A, Santoro C, Gustincich S, Persichetti F.
|
| J Biol Chem 286(28):25108-17. Epub 2011 Mar 25.
2011
|
| 44 | RIPK2, TRAF6
|
| TRAF6 regulates proliferation and differentiation of skeletal myoblasts.
|
| Mueck T, Berger F, Buechsler I, Valchanova RS, Landuzzi L, Lollini PL, Klingel K, Munz B.
|
| Differentiation 81(2):99-106. doi: 10.1016/j.diff.2010.11.002. Epub 2010 Dec 4.
2011
|
| 45 | DEL5QMD, TIRAP, TRAF6
|
| Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
|
| Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, Hirst M, Hogge D, Marra M, Wells RA, Buckstein R, Lam W, Humphries RK, Karsan A.
|
| Nat Med 16(1):49-58. Epub 2009 Nov 8.
2010
|
| 46 | NUMBL, TRAF6
|
| NUMBL interacts with TRAF6 and promotes the degradation of TRAF6.
|
| Zhou L, Ma Q, Shi H, Huo K.
|
| Biochem Biophys Res Commun 392(3):409-14. Epub 2010 Jan 15.
2010
|
| 47 | OTUB1, OTUB2, TRAF3, TRAF6
|
| Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
|
| Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB.
|
| J Biol Chem 285(7):4291-7. Epub 2009 Dec 7.
2010
|
| 48 | IKBKG, IP2, TRAF6
|
| Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.
|
| Gautheron J, Pescatore A, Fusco F, Esposito E, Yamaoka S, Agou F, Ursini MV, Courtois G.
|
| Hum Mol Genet 19(16):3138-49. Epub 2010 Jun 7.PMID: 20529958 2010
|
| 49 | SNCA, TRAF6
|
| TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.
|
| Zucchelli S, Codrich M, Marcuzzi F, Pinto M, Vilotti S, Biagioli M, Ferrer I, Gustincich S.
|
| Hum Mol Genet 19(19):3759-70. Epub 2010 Jul 14.
2010
|
| 50 | GLRX, TRAF6
|
| Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling.
|
| Chantzoura E, Prinarakis E, Panagopoulos D, Mosialos G, Spyrou G.
|
| Biochem Biophys Res Commun 403(3-4):335-9. Epub 2010 Nov 13.
2010
|
| 51 | CSF2RB, NFKB1, TRAF6
|
| A novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit.
|
| Meads MB, Li ZW, Dalton WS.
|
| J Immunol 185(3):1606-15. doi: 10.4049/jimmunol.0902026. Epub 2010 Jul 9.
2010
|
| 52 | AKT1, TRAF6
|
| The E3 ligase TRAF6 regulates Akt ubiquitination and activation.
|
| Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK.
|
| Science 325(5944):1134-8.
2009
|
| 53 | TRAF3IP2, TRAF6
|
| Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
|
| Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X.
|
| Sci Signal 2(92):ra63. Erratum in: Sci Signal. 2010;3(121):er3.
2009
|
| 54 | MAP3K7, TRAF6, UBE2N, UBE2V1
|
| Direct activation of protein kinases by unanchored polyubiquitin chains.
|
| Xia ZP, Sun L, Chen X, Pineda G, Jiang X, Adhikari A, Zeng W, Chen ZJ.
|
| Nature 461(7260):114-9. doi: 10.1038/nature08247. Epub 2009 Aug 12.
2009
|
| 55 | MAPKBP1, NR2C2, TRAF2, TRAF6
|
| JNK-binding protein 1 regulates NF-kappaB activation through TRAF2 and TAK1.
|
| Yamaguchi T, Miyashita C, Koyano S, Kanda H, Yoshioka K, Shiba T, Takamatsu N, Ito M.
|
| Cell Biol Int 33(3):364-8.
2009
|
| 56 | TRAF6, UBE2N
|
| The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL.
|
| Lamothe B, Campos AD, Webster WK, Gopinathan A, Hur L, Darnay BG.
|
| J Biol Chem 283(36):24871-80. Epub 2008 Jul 10.
2008
|
| 57 | TRAF6, GSK3B
|
| TRAF6-mediated regulation of the PI3 kinase (PI3K)-Akt-GSK3beta cascade is required for TNF-induced cell survival.
|
| Yoon K, Jung EJ, Lee SY.
|
| Biochem Biophys Res Commun 371(1):118-21. Epub 2008 Apr 11. 2008
|
| 58 | TRAF6
|
| Identification of a consensus site for TRAF6/p62 polyubiquitination.
|
| Jadhav T, Geetha T, Jiang J, Wooten MW.
|
| Biochem Biophys Res Commun 371(3):521-4. Epub 2008 May 5. 2008
|
| 59 | HSPPD2A, MAP3K1, TRAF6
|
| TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway.
|
| Yoshida R, Takaesu G, Yoshida H, Okamoto F, Yoshioka T, Choi Y, Akira S, Kawai T, Yoshimura A, Kobayashi T.
|
| J Biol Chem 283(52):36211-20. Epub 2008 Nov 4.
2008
|
| 60 | TNFSF11,TRAF6
|
| TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation.
|
| Lamothe B, Webster WK, Gopinathan A, Besse A, Campos AD, Darnay BG.
|
| Biochem Biophys Res Commun 359(4):1044-9. Epub 2007 Jun 11. 2007
|
| 61 | TRAF6
|
| Linkage to chromosome 11p12 in two Maltese families with a highly penetrant form of osteoporosis.
|
| Vidal C, Galea R, Brincat M, Anastasi AX.
|
| Eur J Hum Genet 15(7):800-9. Epub 2007 Mar 21. 2007
|
| 62 | TNFAIP3, TAX1BP1, TRAF6, IRAK1
|
| Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling.
|
| Shembade N, Harhaj NS, Liebl DJ, Harhaj EW.
|
| EMBO J 26(17):3910-22. Epub 2007 Aug 16. 2007
|
| 63 | TRAF6, IKBKG
|
| Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.
|
| Sebban-Benin H, Pescatore A, Fusco F, Pascuale V, Gautheron J, Yamaoka S, Moncla A, Ursini MV, Courtois G.
|
| Hum Mol Genet 16(23):2805-15. Epub 2007 Aug 29. 2007
|
| 64 | IL17F, TRAF6, IL17RA
|
| Interleukin-17F signaling requires ubiquitination of interleukin-17 receptor via TRAF6.
|
| Rong Z, Cheng L, Ren Y, Li Z, Li Y, Li X, Li H, Fu XY, Chang Z.
|
| Cell Signal 19(7):1514-20. Epub 2007 Feb 6. 2007
|
| 65 | TRAF6
|
| TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis.
|
| King CG, Kobayashi T, Cejas PJ, Kim T, Yoon K, Kim GK, Chiffoleau E, Hickman SP, Walsh PT, Turka LA, Choi Y.
|
| Nat Med 12(9):1088-92. Epub 2006 Jul 20. 2006
|
| 66 | EDAR, EDARADD, MAP3K7, TAB2, TRAF6
|
| TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.
|
| Morlon A, Munnich A, Smahi A.
|
| Hum Mol Genet 14(23):3751-7. Epub 2005 Oct 26. 2005
|
| 67 | TICAM1, TRAF4, TRAF6
|
| TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.
|
| Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S, Suzuki K.
|
| Eur J Immunol 35(8):2477-85. 2005
|
| 68 | FHL2,TNFRSF11A,TRAF6
|
| FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner.
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