Citations for
Structure of the TRAF4 TRAF domain with a coiled-coil domain and its implications for the TRAF4 signalling pathway.
Yoon JH, Cho YJ, Park HH.
Acta Crystallogr D Biol Crystallogr 70(Pt 1):2-10. doi: 10.1107/S139900471302333X. Epub 2013 Dec 24. 2014
TRAF4 participates in Wnt/β-catenin signaling in breast cancer by upregulating β-catenin and mediating its translocation to the nucleus.
Wang A, Wang J, Ren H, Yang F, Sun L, Diao K, Zhao Z, Song M, Cui Z, Wang E, Wei M, Mi X.
Mol Cell Biochem 395(1-2):211-9. doi: 10.1007/s11010-014-2127-y. Epub 2014 Jul 3. 2014
TRAF2 regulates the cytoplasmic/nuclear distribution of TRAF4 and its biological function in breast cancer cells.
Zhang X, Wen Z, Sun L, Wang J, Song M, Wang E, Mi X.
Biochem Biophys Res Commun 436(2):344-8. doi: 10.1016/j.bbrc.2013.05.107. Epub 2013 Jun 4. 2013
TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.
Zhang L, Zhou F, García de Vinuesa A, de Kruijf EM, Mesker WE, Hui L, Drabsch Y, Li Y, Bauer A, Rousseau A, Sheppard KA, Mickanin C, Kuppen PJ, Lu CX, Ten Dijke P.
Mol Cell 51(5):559-72. doi: 10.1016/j.molcel.2013.07.014. Epub 2013 Aug 22. 2013
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.
Rousseau A, McEwen AG, Poussin-Courmontagne P, Rognan D, Nominé Y, Rio MC, Tomasetto C, Alpy F.
PLoS Biol 11(12):e1001726. doi: 10.1371/journal.pbio.1001726. Epub 2013 Dec 3. 2013
TRAF4 is a critical molecule for Akt activation in lung cancer.
Li W, Peng C, Lee MH, Lim D, Zhu F, Fu Y, Yang G, Sheng Y, Xiao L, Dong X, Ma W, Bode AM, Cao Y, Dong Z.
Cancer Res 73(23):6938-50. doi: 10.1158/0008-5472.CAN-13-0913. Epub 2013 Oct 23. 2013
Structural biology study of human TNF receptor associated factor 4 TRAF domain.
Niu F, Ru H, Ding W, Ouyang S, Liu ZJ.
Protein Cell rotein Cell. 2013 Aug 27. [Epub ahead of print] 2013
Preliminary X-ray crystallographic studies of the TRAF domain of human TRAF4.
Yoon JH, Park HH.
Acta Crystallogr Sect F Struct Biol Cryst Commun 69(Pt 9):1026-8. doi: 10.1107/S1744309113021192. Epub 2013 Aug 21. 2013
Preliminary X-ray crystallographic studies of the short form of the human TRAF4 TRAF domain.
Yoon JH, Park HH.
Acta Crystallogr Sect F Struct Biol Cryst Commun 69(Pt 8):916-9. doi: 10.1107/S1744309113019179. Epub 2013 Jul 27. 2013
In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis.
Blaise S, Kneib M, Rousseau A, Gambino F, Chenard MP, Messadeq N, Muckenstrum M, Alpy F, Tomasetto C, Humeau Y, Rio MC.
PLoS One 7(2):e30917. doi: 10.1371/journal.pone.0030917. Epub 2012 Feb 17. 2012
IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.
Marinis JM, Hutti JE, Homer CR, Cobb BA, Cantley LC, McDonald C, Abbott DW.
Mol Cell Biol 32(13):2479-89. doi: 10.1128/MCB.00106-12. Epub 2012 Apr 30. 2012
A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.
Marinis JM, Homer CR, McDonald C, Abbott DW.
J Biol Chem 286(3):1938-50. Epub 2010 Nov 19. 2011
Role for Traf4 in polarizing adherens junctions as a prerequisite for efficient cell shape changes.
Mathew SJ, Rembold M, Leptin M.
Mol Cell Biol 31(24):4978-93. doi: 10.1128/MCB.05542-11. Epub 2011 Oct 10. 2011
TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets.
Arthur JF, Shen Y, Gardiner EE, Coleman L, Murphy D, Kenny D, Andrews RK, Berndt MC.
J Thromb Haemost 9(1):163-72. doi: 10.1111/j.1538-7836.2010.04091.x. Erratum in: J Thromb Haemost. 2011 Dec;9(12):2523. Murphy, D [added]. 2011
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.
Li S, Lu K, Wang J, An L, Yang G, Chen H, Cui Y, Yin X, Xie P, Xing G, He F, Zhang L.
Mol Cell Biochem 338(1-2):11-7. doi: 10.1007/s11010-009-0315-y. Epub 2009 Nov 24. 2010
Tumor necrosis factor-receptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation.
Kalkan T, Iwasaki Y, Park CY, Thomsen GH.
Mol Biol Cell 20(14):3436-50. doi: 10.1091/mbc.E08-03-0325. Epub 2009 May 20. 2009
Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis.
Kédinger V, Alpy F, Baguet A, Polette M, Stoll I, Chenard MP, Tomasetto C, Rio MC.
PLoS One 3(10):e3518. Epub 2008 Oct 27. Erratum in: PLoS ONE. 2008;3(11). doi: 10.1371/annotation/2019a487-1af6-4f4e-882a-16398799e882. P 2008
TRAF4 is potently induced by TAp63 isoforms and localised according to differentiation in SCCHN.
Gu X, Coates PJ, MacCallum SF, Boldrup L, Sjöström B, Nylander K.
Cancer Biol Ther 6(12):1986-90. Epub 2007 Sep 8.PMID: 18087216 2007
TRAF4 overexpression is a common characteristic of human carcinomas.
Camilleri-Broët S, Cremer I, Marmey B, Comperat E, Viguié F, Audouin J, Rio MC, Fridman WH, Sautčs-Fridman C, Régnier CH.
Oncogene 26(1):142-7. Epub 2006 Jun 26.PMID: 16799635 2007
TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.
Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S, Suzuki K.
Eur J Immunol 35(8):2477-85. 2005
MEKK4 is an effector of the embryonic TRAF4 for JNK activation.
Abell AN, Johnson GL.
J Biol Chem 280(43):35793-6. Epub 2005 Sep 12.PMID: 16157600 2005
Identification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic gene.
Sax JK, El-Deiry WS.
J Biol Chem 278(38):36435-44. Epub 2003 Jun 4. 2003
Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.
Regnier CH, Masson R, Kedinger V, Textoris J, Stoll I, Chenard MP, Dierich A, Tomasetto C, Rio MC.
Proc Natl Acad Sci U S A 99(8):5585-90. 2002
Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4).
Glauner H, Siegmund D, Motejadded H, Scheurich P, Henkler F, Janssen O, Wajant H.
Eur J Biochem 269(19):4819-29. 2002
Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development.
Masson R, Regnier CH, Chenard MP, Wendling C, Mattei MG, Tomasetto C, Rio MC.
Mech Dev 71(1-2):187-91 1998
Human TNF receptor-associated factor 5 (TRAF5) : cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Nakano H, Shindo M, Yamada K, Yoshida MC, Santee SM, Ware CF, Jenkins NA, Gilbert DJ, Yagita H, Copeland NC, Okumura K.
Genomics 42(1):26-32. 1997
Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer.
Biche I, et al.
Cancer Res 56 : 3886-3890. 1996
Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.
Tomasetto C, et al.
Genomics 28 : 367-376. 1995
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma.
RŽgnier CH, et al.
J Biol Chem 270 : 25715-25721. 1995