| 1 | TPM2
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| Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer.
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| Zhang J, Zhang J, Xu S, Zhang X, Wang P, Wu H, Xia B, Zhang G, Lei B, Wan L, Zhang D, Pang D.
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| Cell Physiol Biochem 45(2):692-705. doi: 10.1159/000487162. Epub 2018 Jan 31.
2018
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| 2 | AMCD2B, MYH3, SHHS, SHHS2, TNNI2, TNNT3, TPM2
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| A MYH3 mutation identified for the first time in a Chinese family with Sheldon-Hall syndrome (DA2B).
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| Xu Y, Kang QL, Zhang ZL.
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| Neuromuscul Disord 28(5):456-462. doi: 10.1016/j.nmd.2018.03.002. Epub 2018 Mar 8. 2018
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| 3 | NEM4, TPM2
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| Molecular mechanisms of dysfunction of muscle fibres associated with Glu139 deletion in TPM2 gene.
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| Borovikov YS, Rysev NA, Karpicheva OE, Sirenko VV, Avrova SV, Piers A, Redwood CS.
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| Sci Rep 7(1):16797. doi: 10.1038/s41598-017-17076-9.
2017
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| 4 | SMAD4, TPM2
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| Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2.
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| Hsu WL, Ma YL, Liu YC, Lee EHY.
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| BMC Biol 15(1):112. doi: 10.1186/s12915-017-0452-9.
2017
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| 5 | TPM2
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| Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices.
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| Wolfenson H, Meacci G, Liu S, Stachowiak MR, Iskratsch T, Ghassemi S, Roca-Cusachs P, O'Shaughnessy B, Hone J, Sheetz MP.
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| Nat Cell Biol 18(1):33-42. doi: 10.1038/ncb3277. Epub 2015 Nov 30.
2016
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| 6 | NEM1, NEM4, TPM2, TPM3
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| Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies.
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| Marttila M, Lehtokari VL, Marston S, Nyman TA, Barnerias C, Beggs AH, Bertini E, Ceyhan-Birsoy O, Cintas P, Gerard M, Gilbert-Dussardier B, Hogue JS, Longman C, Eymard B, Frydman M, Kang PB, Klinge L, Kolski H, Lochmüller H, Magy L, Manel V, Mayer M, Mercuri E, North KN, Peudenier-Robert S, Pihko H, Probst FJ, Reisin R, Stewart W, Taratuto AL, de Visser M, Wilichowski E, Winer J, Nowak K, Laing NG, Winder TL, Monnier N, Clarke NF, Pelin K, Grönholm M, Wallgren-Pettersson C.
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| Hum Mutat 35(7):779-90. doi: 10.1002/humu.22554. Epub 2014 May 1.
2014
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| 7 | TPM2
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| Trop2 regulates the proliferation and differentiation of murine compact-bone derived MSCs.
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| Yang J, Zhu Z, Wang H, Li F, Du X, Ma RZ.
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| Int J Oncol 43(3):859-67. doi: 10.3892/ijo.2013.1987. Epub 2013 Jun 19.
2013
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| 8 | AMCD1, SHHS2, TPM2
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| Novel deletion of lysine 7 expands the clinical, histopathological and genetic spectrum of TPM2-related myopathies.
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| Davidson AE, Siddiqui FM, Lopez MA, Lunt P, Carlson HA, Moore BE, Love S, Born DE, Roper H, Majumdar A, Jayadev S, Underhill HR, Smith CO, von der Hagen M, Hubner A, Jardine P, Merrison A, Curtis E, Cullup T, Jungbluth H, Cox MO, Winder TL, Abdel Salam H, Li JZ, Moore SA, Dowling JJ.
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| Brain 136(Pt 2):508-21. doi: 10.1093/brain/aws344.
2013
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| 9 | NEM1, NEM4, TPM2, TPM3
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| Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms.
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| Ochala J, Gokhin DS, Pénisson-Besnier I, Quijano-Roy S, Monnier N, Lunardi J, Romero NB, Fowler VM.
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| Hum Mol Genet 21(20):4473-85. Epub 2012 Jul 13.
2012
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| 10 | NEM4, TPM2
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| Whole-Body muscle MRI in a series of patients with congenital myopathy related to TPM2 gene mutations.
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| Jarraya M, Quijano-Roy S, Monnier N, Béhin A, Avila-Smirnov D, Romero NB, Allamand V, Richard P, Barois A, May A, Estournet B, Mercuri E, Carlier PG, Carlier RY.
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| Neuromuscul Disord 22 Suppl 2:S137-47. doi: 10.1016/j.nmd.2012.06.347.
2012
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| 11 | NEM4, TPM2
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| Abnormal actin binding of aberrant β-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap myopathy.
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| Marttila M, Lemola E, Wallefeld W, Memo M, Donner K, Laing NG, Marston S, Grönholm M, Wallgren-Pettersson C.
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| Biochem J 442(1):231-9. doi: 10.1042/BJ20111030.
2012
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| 12 | CELF1, PTBP1, PTBP2, TPM2
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| CELF and PTB proteins modulate the inclusion of the β-tropomyosin exon 6B during myogenic differentiation.
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| Sureau A, Saulière J, Expert-Bezançon A, Marie J.
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| Exp Cell Res 317(1):94-106. Epub 2010 Sep 25.
2011
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| 13 | NEM4, TPM2
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| A myopathy-linked tropomyosin mutation severely alters thin filament conformational changes during activation.
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| Ochala J, Iwamoto H, Larsson L, Yagi N.
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| Proc Natl Acad Sci U S A 107(21):9807-12. Epub 2010 May 10.PMID: 20457903 2010
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| 14 | TPM2
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| Cap disease due to mutation of the beta-tropomyosin gene (TPM2).
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| Clarke NF, Domazetovska A, Waddell L, Kornberg A, McLean C, North KN.
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| Neuromuscul Disord 19(5):348-51. Epub 2009 Apr 3.
2009
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| 15 | TPM1, TPM2, TPM3, TPM4
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| Human tropomyosin isoforms in the regulation of cytoskeleton functions.
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| Lin JJ, Eppinga RD, Warren KS, McCrae KR.
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| Adv Exp Med Biol 644:201-22. Review.
2008
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| 16 | TPM1, TPM2, TPM3, TPM4
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| Tropomyosins in skeletal muscle diseases.
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| Kee AJ, Hardeman EC.
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| Adv Exp Med Biol 644:143-57. Review.
2008
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| 17 | NEM4, TPM2
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| New morphologic and genetic findings in cap disease associated with beta-tropomyosin (TPM2) mutations.
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| Ohlsson M, Quijano-Roy S, Darin N, Brochier G, Lacène E, Avila-Smirnow D, Fardeau M, Oldfors A, Tajsharghi H.
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| Neurology 71(23):1896-901.
2008
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| 18 | NEM4, TPM2
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| Beta-tropomyosin mutations alter tropomyosin isoform composition.
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| Nilsson J, Tajsharghi H.
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| Eur J Neurol 15(6):573-8. Epub 2008 Apr 14.
2008
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| 19 | TPM2, AMCD1
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| Distal arthrogryposis and muscle weakness associated with a beta-tropomyosin mutation.
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| Tajsharghi H, Kimber E, Holmgren D, Tulinius M, Oldfors A.
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| Neurology 68(10):772-5. 2007
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| 20 | AMCD1, AMCD2B, TNNI2, TNNT3, TPM2
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| Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function.
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| Robinson P, Lipscomb S, Preston LC, Altin E, Watkins H, Ashley CC, Redwood CS.
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| FASEB J 21(3):896-905. Epub 2006 Dec 27.
2007
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| 21 | NEM4, TPM2
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| Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2).
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| Tajsharghi H, Ohlsson M, Lindberg C, Oldfors A.
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| Arch Neurol 64(9):1334-8.
2007
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| 22 | SHHS2, TPM2
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| Distal arthrogryposis and muscle weakness associated with a beta-tropomyosin mutation.
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| Tajsharghi H, Kimber E, Holmgren D, Tulinius M, Oldfors A.
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| Neurology 68(10):772-5. 2007
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| 23 | AMCD1, AMCD2B, TNNI2, TPM2
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| Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes
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| Sung SS, Brassington AM, Grannatt K, Rutherford A, Whitby FG, Krakowiak PA, Jorde LB, Carey JC, Bamshad M.
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| Am J Hum Genet 72(3):681-90. 2003
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| 24 | TPM2, NEM4
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| Mutations in the beta-tropomyosin (TPM2) gene--a rare cause of nemaline myopathy.
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| Donner K, Ollikainen M, Ridanpaa M, Christen HJ, Goebel HH, de Visser M, Pelin K, Wallgren-Pettersson C.
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| Neuromuscul Disord 12(2):151-8. 2002
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| 25 | TNNC2, TNNI1, TNNI2, TPM1, TPM2
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| Fine mapping of five human skeletal muscle genes : alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast.
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| Tiso N, et al.
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| Biochem Biophys Res Commun 230 : 347-350. 1997
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| 26 | TPM2
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| Assignment of the human beta tropomyosin gene (TPM2) to band 9p13 by fluorescence in situ hybridisation.
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| Hunt CCJ, et al.
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| Cytogenet Cell Genet 71 : 94-95. 1995
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