| 1 | CMH3, TPM1
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| The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle.
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| Rysev NA, Karpicheva OE, Redwood CS, Borovikov YS.
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| Biochim Biophys Acta 1824(2):366-73. doi: 10.1016/j.bbapap.2011.11.004. Epub 2011 Dec 3.
2012
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| 2 | TNNC1, TNNI3, TPM1
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| Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.
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| Asumda FZ, Chase PB.
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| Differentiation 83(3):106-15. doi: 10.1016/j.diff.2011.10.002.
2012
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| 3 | TPM1, TPM3
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| Functional structure of the promoter regions for the predominant low molecular weight isoforms of tropomyosin in human kidney cells.
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| Savill SA, Leitch HF, Harvey JN, Thomas TH.
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| J Cell Biochem 113(11):3576-86. doi: 10.1002/jcb.24236.
2012
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| 4 | LVNC9, TPM1
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| Identification of a novel TPM1 mutation in a family with left ventricular noncompaction and sudden death.
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| Chang B, Nishizawa T, Furutani M, Fujiki A, Tani M, Kawaguchi M, Ibuki K, Hirono K, Taneichi H, Uese K, Onuma Y, Bowles NE, Ichida F, Inoue H, Matsuoka R, Miyawaki T; Noncompaction study collaborators.
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| Mol Genet Metab 102(2):200-6. Epub 2010 Sep 29. 2011
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| 5 | CMH3, TPM1
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| Several cardiomyopathy causing mutations on tropomyosin either destabilize the active state of actomyosin or alter the binding properties of tropomyosin.
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| Mathur MC, Chase PB, Chalovich JM.
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| Biochem Biophys Res Commun 406(1):74-8. Epub 2011 Feb 3.
2011
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| 6 | CMH3, TPM1
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| Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy.
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| Caleshu C, Sakhuja R, Nussbaum RL, Schiller NB, Ursell PC, Eng C, De Marco T, McGlothlin D, Burchard EG, Rame JE.
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| Am J Med Genet A 155A(9):2229-35. doi: 10.1002/ajmg.a.34097. Epub 2011 Aug 5.
2011
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| 7 | LVNC9, TPM1
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| Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype.
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| Probst S, Oechslin E, Schuler P, Greutmann M, Boyé P, Knirsch W, Berger F, Thierfelder L, Jenni R, Klaassen S.
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| Circ Cardiovasc Genet 4(4):367-74. Epub 2011 May 6. 2011
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| 8 | CMD1Y, TPM1
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| The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle.
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| Borovikov YS, Avrova SV, Karpicheva OE, Robinson P, Redwood CS.
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| Biochem Biophys Res Commun 411(3):496-500. Epub 2011 Jun 29.
2011
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| 9 | TNNC1, TPM1
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| Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.
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| Weymouth KS, Blanton SH, Bamshad MJ, Beck AE, Alvarez C, Richards S, Gurnett CA, Dobbs MB, Barnes D, Mitchell LE, Hecht JT.
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| Am J Med Genet A 155A(9):2170-9. doi: 10.1002/ajmg.a.34167. Epub 2011 Aug 10.
2011
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| 10 | TPM1
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| Polymorphisms in the tropomyosin TPM1 short isoform promoter alter gene expression and are associated with increased risk of metabolic syndrome.
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| Savill SA, Leitch HF, Daly AK, Harvey JN, Thomas TH.
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| Am J Hypertens 23(4):399-404. Epub 2010 Jan 14.
2010
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| 11 | TPM1
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| Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform.
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| Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF.
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| Circulation 121(3):410-8. Epub 2010 Jan 11.
2010
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| 12 | CMD1Y, TPM1
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| Dilated cardiomyopathy mutations in alpha-tropomyosin inhibit its movement during the ATPase cycle.
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| Borovikov YS, Karpicheva OE, Chudakova GA, Robinson P, Redwood CS.
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| Biochem Biophys Res Commun 381(3):403-6. Epub 2009 Feb 15.
2009
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| 13 | ACTC1, CFMH4, CMH1, CMH11, MYBPC3, MYH7, MYL2, MYL3, PRKAG2, TNNI3, TNNT2, TPM1
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| Shared genetic causes of cardiac hypertrophy in children and adults.
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| Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE.
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| N Engl J Med 358(18):1899-908. Epub 2008 Apr 9. 2008
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| 14 | TPM1, TPM2, TPM3, TPM4
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| Human tropomyosin isoforms in the regulation of cytoskeleton functions.
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| Lin JJ, Eppinga RD, Warren KS, McCrae KR.
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| Adv Exp Med Biol 644:201-22. Review.
2008
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| 15 | TPM1, TPM2, TPM3, TPM4
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| Tropomyosins in skeletal muscle diseases.
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| Kee AJ, Hardeman EC.
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| Adv Exp Med Biol 644:143-57. Review.
2008
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| 16 | NEBL, TPM1
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| The nebulette repeat domain is necessary for proper maintenance of tropomyosin with the cardiac sarcomere.
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| Bonzo JR, Norris AA, Esham M, Moncman CL.
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| Exp Cell Res 314(19):3519-30. doi: 10.1016/j.yexcr.2008.09.001. Epub 2008 Sep 16.
2008
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| 17 | CMH3, TPM1
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| Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
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| Robinson P, Griffiths PJ, Watkins H, Redwood CS.
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| Circ Res 101(12):1266-73. Epub 2007 Oct 11.
2007
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| 18 | CMD1Y, TPM1
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| The effect of mutations in alpha-tropomyosin (E40K and E54K) that cause familial dilated cardiomyopathy on the regulatory mechanism of cardiac muscle thin filaments.
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| Mirza M, Robinson P, Kremneva E, Copeland O, Nikolaeva O, Watkins H, Levitsky D, Redwood C, El-Mezgueldi M, Marston S.
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| J Biol Chem 282(18):13487-97. Epub 2007 Mar 13.
2007
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| 19 | TPM1
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| Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB.
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| Lin JC, Tarn WY.
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| Mol Cell Biol 25(22):10111-21. 2005
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| 20 | TPM1
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| Expression of a novel cardiac-specific tropomyosin isoform in humans.
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| Denz CR, Narshi A, Zajdel RW, Dube DK.
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| Biochem Biophys Res Commun 320(4):1291-7. 2004
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| 21 | TPM1
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| Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells.
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| Bharadwaj S, Prasad GL.
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| Cancer Lett 183(2):205-13. 2002
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| 22 | TPM1, TNNT2, MYBPC3, MYH7
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| Novel mutations in sarcomeric protein genes in dilated cardiomyopathy.
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| Daehmlow S, Erdmann J, Knueppel T, Gille C, Froemmel C, Hummel M, Hetzer R, Regitz-Zagrosek V.
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| Biochem Biophys Res Commun 298(1):116-20. 2002
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| 23 | TPM1, CMH3
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| A novel TPM1 mutation in a family with hypertrophic cardiomyopathy and sudden cardiac death in childhood.
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| Van Driest SL, Will ML, Atkins DL, Ackerman MJ.
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| Am J Cardiol 90(10):1123-7. 2002
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| 24 | TPM1
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| Refined localization of the human alpha-tropomyosin gene (TPM1) by genetic mapping.
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| Mogensen J, et al.
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| Cytogenet Cell Genet 84(1-2):35-6. No abstract available 1999
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| 25 | TNNC2, TNNI1, TNNI2, TPM1, TPM2
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| Fine mapping of five human skeletal muscle genes : alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast.
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| Tiso N, et al.
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| Biochem Biophys Res Commun 230 : 347-350. 1997
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| 26 | CMH3, TPM1
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| Clinical features of hypertrophic cardiomyopathy caused by mutation of a hot spot in the alpha-tropomyosin gene.
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| Coviello DA, et al.
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| J Am Coll Cardiol 29 : 635-640. 1997
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| 27 | CMH3, TPM1
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| Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.
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| Golitsina N, et al.
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| Biochemistry 36 : 4637-4642. 1997
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| 28 | CMH3, TPM1
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| Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility.
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| Bing W, Redwood CS, Purcell IF, Esposito G, Watkins H, Marston SB.
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| Biochem Biophys Res Commun 236(3):760-4. 1997
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| 29 | CMH3, TPM1
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| A De novo mutation in alpha-tropomyosin that causes hypertrophic cardiomyopathy.
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| Watkins H, et al.
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| Circulation 91 : 2302-2305. 1995
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| 30 | TPM1
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| Assignment of the human skeletal muscle alpha-tropomyosin gene (TPM1) to band 15q22 by fluorescence in situ hybridization.
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| Eyre H, et al.
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| Cytogenet Cell Genet 69 : 15-17. 1995
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| 31 | TPM1, TNNI1, CMH3, CMH2
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| Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy : a disease of the sarcomere.
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| Thierfelder L, et al.
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| Cell 77 : 701-712. 1994
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| 32 | JUN, TPM1
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| Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.
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| Chevray PM, Nathans D.
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| Proc Natl Acad Sci U S A 89(13):5789-93. 1992
|