| 1 | MTSS1, TP63
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| p63 controls cell migration and invasion by transcriptional regulation of MTSS1.
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| Giacobbe A, Compagnone M, Bongiorno-Borbone L, Antonov A, Markert EK, Zhou JH, Annicchiarico-Petruzzelli M, Melino G, Peschiaroli A.
|
| Oncogene 35(12):1602-8. doi: 10.1038/onc.2015.230. Epub 2015 Jun 29.
2016
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| 2 | CLCA2, MPZL2, TP53, TP63
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| CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
|
| Ramena G, Yin Y, Yu Y, Walia V, Elble RC.
|
| PLoS One 11(3):e0147489. doi: 10.1371/journal.pone.0147489. eCollection 2016.
2016
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| 3 | TP63, TRIM29
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| TRIM29 regulates the p63-mediated pathway in cervical cancer cells
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| Masuda Y, Takahashi H, Hatakeyama S.
|
| Biochim Biophys Acta. Oct;1853(10 Pt A):2296-305. doi: 10.1016/j.bbamcr.2015.05.035. Epub 2015 Jun 10. 2015
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| 4 | RBM24, TP63
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| RNA-binding protein RBM24 regulates p63 expression via mRNA stability.
|
| Xu E, Zhang J, Zhang M, Jiang Y, Cho SJ, Chen X.
|
| Mol Cancer Res 12(3):359-69. doi: 10.1158/1541-7786.MCR-13-0526. Epub 2013 Dec 27.
2014
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| 5 | TP63
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| ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.
|
| Balboni AL, Hutchinson JA, DeCastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, DiRenzo J.
|
| Cancer Res 73(2):1020-30. doi: 10.1158/0008-5472.CAN-12-2862. Epub 2012 Dec 14.
2013
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| 6 | CDKN1A, RNF144B, TP63
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| PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63.
|
| Conforti F, Yang AL, Piro MC, Mellone M, Terrinoni A, Candi E, Tucci P, Thomas GJ, Knight RA, Melino G, Sayan BS.
|
| Oncogene 32(40):4758-65. doi: 10.1038/onc.2012.497. Epub 2012 Nov 5.
2013
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| 7 | FANCD2, TP63
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| FANCD2 activates transcription of TAp63 and suppresses tumorigenesis.
|
| Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD.
|
| Mol Cell 50(6):908-18. doi: 10.1016/j.molcel.2013.05.017.
2013
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| 8 | AEC, TP63
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| p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.
|
| Ferone G, Mollo MR, Thomason HA, Antonini D, Zhou H, Ambrosio R, De Rosa L, Salvatore D, Getsios S, van Bokhoven H, Dixon J, Missero C.
|
| Hum Mol Genet 22(3):531-43. doi: 10.1093/hmg/dds464. Epub 2012 Oct 29.
2013
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| 9 | GLS2, TP63
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| p63 regulates glutaminase 2 expression.
|
| Giacobbe A, Bongiorno-Borbone L, Bernassola F, Terrinoni A, Markert EK, Levine AJ, Feng Z, Agostini M, Zolla L, Agrò AF, Notterman DA, Melino G, Peschiaroli A.
|
| Cell Cycle 12(9):1395-405. doi: 10.4161/cc.24478. Epub 2013 Apr 10.
2013
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| 10 | AEC, TP63, ZNF750
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| Genomic Profiling of a Human Organotypic Model of AEC Syndrome Reveals ZNF750 as an Essential Downstream Target of Mutant TP63.
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| Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA.
|
| Am J Hum Genet 91(3):435-43. Epub 2012 Aug 23.
2012
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| 11 | TP63
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| Insertion/deletion polymorphisms in the ΔNp63 promoter are a risk factor for bladder exstrophy epispadias complex.
|
| Wilkins S, Zhang KW, Mahfuz I, Quantin R, D'Cruz N, Hutson J, Ee M, Bagli D, Aitken K, Fong FN, Ng PK, Tsui SK, Fung WY, Banu T, Thakre A, Johar K, Jaureguizar E, Li L, Cheng W.
|
| PLoS Genet 8(12):e1003070. doi: 10.1371/journal.pgen.1003070. Epub 2012 Dec 20.
2012
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| 12 | ADULT, TP63
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| ADULT syndrome due to an R243W mutation in TP63.
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| Berk DR, Armstrong NL, Shinawi M, Whelan AJ.
|
| Int J Dermatol 51(6):693-6. doi: 10.1111/j.1365-4632.2011.05375.x.
2012
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| 13 | TBL1XR1, TP63
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| TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma.
|
| Scott DW, Mungall KL, Ben-Neriah S, Rogic S, Morin RD, Slack GW, Tan KL, Chan FC, Lim RS, Connors JM, Marra MA, Mungall AJ, Steidl C, Gascoyne RD.
|
| Blood 119(21):4949-52. doi: 10.1182/blood-2012-02-414441. Epub 2012 Apr 11.
2012
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| 14 | BBC3, PMAIP1, TP53, TP63
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| DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa.
|
| Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, Strasser A.
|
| Mol Cell 48(3):343-52. doi: 10.1016/j.molcel.2012.08.017. Epub 2012 Sep 20.
2012
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| 15 | ID2, TP63
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| Large scale RNAi screen reveals that the inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation.
|
| Wu N, Castel D, Debily MA, Vigano MA, Alibert O, Mantovani R, Iljin K, Romeo PH, Gidrol X.
|
| J Biol Chem 286(23):20870-9. Epub 2011 Apr 10.
2011
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| 16 | TP63
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| Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements.
|
| Chen C, Gorlatova N, Kelman Z, Herzberg O.
|
| Proc Natl Acad Sci U S A 108(16):6456-61. Epub 2011 Apr 4.
2011
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| 17 | TP63
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| Mutation in SAM domain of TP63 is associated with nonsyndromic cleft lip and palate and cleft palate.
|
| Kantaputra PN, Malaivijitnond S, Vieira AR, Heering J, Dötsch V, Khankasikum T, Sripathomsawat W.
|
| Am J Med Genet A 155A(6):1432-6. doi: 10.1002/ajmg.a.34011. Epub 2011 May 12.
2011
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| 18 | SFN, TP63
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| 14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
|
| Li Q, Sambandam SA, Lu HJ, Thomson A, Kim SH, Lu H, Xin Y, Lu Q.
|
| Carcinogenesis 32(12):1782-8. Epub 2011 Sep 16.
2011
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| 19 | SATB1, TP63
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| p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis.
|
| Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA.
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| J Cell Biol 194(6):825-39.
2011
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| 20 | SATB2, TP63
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| Special AT-rich binding protein-2 (SATB2) differentially affects disease-causing p63 mutant proteins.
|
| Chung J, Grant RI, Kaplan DR, Irwin MS.
|
| J Biol Chem 286(47):40671-80. doi: 10.1074/jbc.M111.271189. Epub 2011 Sep 29.
2011
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| 21 | TP63
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| TP63 P2 promoter functional analysis identifies β-catenin as a key regulator of ΔNp63 expression.
|
| Ruptier C, De Gaspéris A, Ansieau S, Granjon A, Tanière P, Lafosse I, Shi H, Petitjean A, Taranchon-Clermont E, Tribollet V, Voeltzel T, Scoazec JY, Maguer-Satta V, Puisieux A, Hainaut P, Cavard C, Caron de Fromentel C.
|
| Oncogene 30(46):4656-65. doi: 10.1038/onc.2011.171. Epub 2011 Jun 6.
2011
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| 22 | ADULT, TP63
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| Cleft palate and ADULT phenotype in a patient with a novel TP63 mutation suggests lumping of EEC/LM/ADULT syndromes into a unique entity: ELA syndrome.
|
| Prontera P, Garelli E, Isidori I, Mencarelli A, Carando A, Silengo MC, Donti E.
|
| Am J Med Genet A 155A(11):2746-9. doi: 10.1002/ajmg.a.34270. Epub 2011 Oct 11.
2011
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| 23 | RBM38, TP63
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| RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability.
|
| Zhang J, Jun Cho S, Chen X.
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| Proc Natl Acad Sci U S A 107(21):9614-9. Epub 2010 May 10. 2010
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| 24 | DICER1, TP63
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| TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
|
| Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER.
|
| Nature 467(7318):986-90.
2010
|
| 25 | POU2F3, TP63
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| Skn-1a/Oct-11 and delta Np63alpha exert antagonizing effects on human keratin expression.
|
| Lena AM, Cipollone R, Amelio I, Catani MV, Ramadan S, Browne G, Melino G, Candi E.
|
| Biochem Biophys Res Commun 401(4):568-73. Epub 2010 Oct 1. 2010
|
| 26 | TP53, TP63
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| TAp63 plays compensatory roles in p53-deficient cancer cells under genotoxic stress.
|
| Yao JY, Chen JK.
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| Biochem Biophys Res Commun 403(3-4):310-5. Epub 2010 Nov 12.
2010
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| 27 | ADRM1, NOS2, TP63
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| Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation.
|
| Huang Y, Ratovitski EA.
|
| J Biol Chem 285(53):41422-31. doi: 10.1074/jbc.M110.158642. Epub 2010 Oct 19.
2010
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| 28 | AIRE, TP63
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| Wild-type AIRE cooperates with p63 in HLA class II expression of medullary thymic stromal cells.
|
| Tonooka A, Kubo T, Ichimiya S, Tamura Y, Ilmarinen T, Ulmanen I, Kimura S, Yokoyama S, Takano Y, Kikuchi T, Sato N.
|
| Biochem Biophys Res Commun 379(3):765-70. Epub 2009 Jan 3.
2009
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| 29 | FAS, TP53, TP63, TP73
|
| Active transcription of the human FAS/CD95/TNFRSF6 gene involves the p53 family.
|
| Schilling T, Schleithoff ES, Kairat A, Melino G, Stremmel W, Oren M, Krammer PH, Müller M.
|
| Biochem Biophys Res Commun 387(2):399-404. Epub 2009 Jul 16.
2009
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| 30 | ADULT, TP63
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| A novel TP63 mutation in family with ADULT syndrome presenting with eczema and hypothelia.
|
| van Zelst-Stams WA, van Steensel MA.
|
| Am J Med Genet A 149A(7):1558-60. No abstract available. PMID: 19530185 2009
|
| 31 | PLK1, TP63
|
| Plk1 regulates liver tumor cell death by phosphorylation of TAp63.
|
| Komatsu S, Takenobu H, Ozaki T, Ando K, Koida N, Suenaga Y, Ichikawa T, Hishiki T, Chiba T, Iwama A, Yoshida H, Ohnuma N, Nakagawara A, Kamijo T.
|
| Oncogene 28(41):3631-41. Epub 2009 Aug 10.
2009
|
| 32 | AEC, TP63
|
| Dermatologic findings of ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome.
|
| Julapalli MR, Scher RK, Sybert VP, Siegfried EC, Bree AF.
|
| Am J Med Genet A 149A(9):1900-6.PMID: 19681128 2009
|
| 33 | AEC, TP63
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| Oral findings in ankyloblepharon-ectodermal dysplasia-cleft lip/palate (AEC) syndrome.
|
| Farrington F, Lausten L.
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| Am J Med Genet A 149A(9):1907-9.PMID: 19681142 2009
|
| 34 | AEC, TP63
|
| Facial clefting and oroauditory pathway manifestations in ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome.
|
| Cole P, Hatef DA, Kaufman Y, Magruder A, Bree A, Friedman E, Sindwani R, Hollier LH Jr.
|
| Am J Med Genet A 149A(9):1910-5.PMID: 19697430 2009
|
| 35 | AEC, TP63
|
| Spectrum of p63 mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC).
|
| Rinne T, Bolat E, Meijer R, Scheffer H, van Bokhoven H.
|
| Am J Med Genet A 149A(9):1948-51.PMID: 19676060 2009
|
| 36 | TP63
|
| TAp63 induces senescence and suppresses tumorigenesis in vivo.
|
| Guo X, Keyes WM, Papazoglu C, Zuber J, Li W, Lowe SW, Vogel H, Mills AA.
|
| Nat Cell Biol 11(12):1451-7. Epub 2009 Nov 8.PMID: 19898465 2009
|
| 37 | TP63
|
| Identification and functional characterization of two new transcriptional variants of the human p63 gene.
|
| Mangiulli M, Valletti A, Caratozzolo MF, Tullo A, Sbisà E, Pesole G, D'Erchia AM.
|
| Nucleic Acids Res 37(18):6092-104. Epub 2009 Aug 21.PMID: 19700772 2009
|
| 38 | DLX3, TP63
|
| Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation.
|
| Di Costanzo A, Festa L, Duverger O, Vivo M, Guerrini L, La Mantia G, Morasso MI, Calabrò V.
|
| Cell Cycle 8(8):1185-95. Epub 2009 Apr 16.
2009
|
| 39 | PPP1R13B, TP53, TP53BP2, TP63, TP73
|
| Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.
|
| Patel S, George R, Autore F, Fraternali F, Ladbury JE, Nikolova PV.
|
| Nucleic Acids Res 36(16):5139-51. Epub 2008 Aug 2.
2008
|
| 40 | S100A2, TP63
|
| Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.
|
| Kirschner RD, Sänger K, Müller GA, Engeland K.
|
| Nucleic Acids Res 36(9):2969-80. Epub 2008 Apr 3.
2008
|
| 41 | AEC, RHS, TP63
|
| A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes.
|
| Rinne T, Clements SE, Lamme E, Duijf PH, Bolat E, Meijer R, Scheffer H, Rosser E, Tan TY, McGrath JA, Schalkwijk J, Brunner HG, Zhou H, van Bokhoven H.
|
| Hum Mol Genet 17(13):1968-77. Epub 2008 Mar 25.
2008
|
| 42 | MYC, TP63, UBCSL
|
| Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
|
| Kiemeney LA, Thorlacius S, Sulem P, Geller F, Aben KK, Stacey SN, Gudmundsson J, Jakobsdottir M, Bergthorsson JT, Sigurdsson A, Blondal T, Witjes JA, Vermeulen SH, Hulsbergen-van de Kaa CA, Swinkels DW, Ploeg M, Cornel EB, Vergunst H, Thorgeirsson TE, Gudbjartsson D, Gudjonsson SA, Thorleifsson G, Kristinsson KT, Mouy M, Snorradottir S, Placidi D, Campagna M, Arici C, Koppova K, Gurzau E, Rudnai P, Kellen E, Polidoro S, Guarrera S, Sacerdote C, Sanchez M, Saez B, Valdivia G, Ryk C, de Verdier P, Lindblom A, Golka K, Bishop DT, Knowles MA, Nikulasson S, Petursdottir V, Jonsson E, Geirsson G, Kristjansson B, Mayordomo JI, Steineck G, Porru S, Buntinx F, Zeegers MP, Fletcher T, Kumar R, Matullo G, Vineis P, Kiltie AE, Gulcher JR, Thorsteinsdottir U, Kong A, Rafnar T, Stefansson K.
|
| Nat Genet 40(11):1307-12. Epub 2008 Sep 14. 2008
|
| 43 | SHISA5, TP63
|
| Scotin: A new p63 target gene expressed during epidermal differentiation.
|
| Zocchi L, Bourdon JC, Codispoti A, Knight R, Lane DP, Melino G, Terrinoni A.
|
| Biochem Biophys Res Commun 367(2):271-6. Epub 2007 Dec 28.
2008
|
| 44 | CCL17, TP63
|
| p63 induces CD4+ T-cell chemoattractant TARC/CCL17 in human epithelial cells.
|
| Kubo T, Ichimiya S, Tonooka A, Nagashima T, Kikuchi T, Sato N.
|
| J Interferon Cytokine Res 28(12):725-32.PMID: 18937546 2008
|
| 45 | GDF15, TP63
|
| TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation.
|
| Ichikawa T, Suenaga Y, Koda T, Ozaki T, Nakagawara A.
|
| Oncogene 27(4):409-20. Epub 2007 Jul 16.PMID: 17637746 2008
|
| 46 | CDH3, TP63
|
| P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle.
|
| Shimomura Y, Wajid M, Shapiro L, Christiano AM.
|
| Development 135(4):743-53. Epub 2008 Jan 16.PMID: 18199584 2008
|
| 47 | TP63, TPRG1
|
| Tprg, a gene predominantly expressed in skin, is a direct target of the transcription factor p63.
|
| Antonini D, Dentice M, Mahtani P, De Rosa L, Della Gatta G, Mandinova A, Salvatore D, Stupka E, Missero C.
|
| J Invest Dermatol 128(7):1676-85. Epub 2008 Feb 7.PMID: 18256694 2008
|
| 48 | GLI2, TP53, TP63, TP73
|
| Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53.
|
| Katoh Y, Katoh M.
|
| Int J Oncol 33(4):881-6.
2008
|
| 49 | OGG1,TP63
|
| TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines.
|
| Upadhyay S, Chatterjee A, Trink B, Sommer M, Ratovitski E, Sidransky D.
|
| Biochem Biophys Res Commun 356(4):823-8. Epub 2007 Feb 7. 2007
|
| 50 | TP63
|
| Novel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach.
|
| Birkaya B, Ortt K, Sinha S.
|
| BMC Mol Biol 8:43. 2007
|
| 51 | TP63, RHS
|
| A new mutation in TP63 is associated with age-related pathology.
|
| Holder-Espinasse M, Martin-Coignard D, Escande F, Manouvrier-Hanu S.
|
| Eur J Hum Genet 15(11):1115-20. Epub 2007 Jul 4. 2007
|
| 52 | TP63, AEC, LMS, SHFM4, ADULT, RHS, EEC3
|
| p63-associated disorders.
|
| Rinne T, Brunner HG, van Bokhoven H.
|
| Cell Cycle 6(3):262-8. Epub 2007 Feb 3. Review. 2007
|
| 53 | TP63, EEC3
|
| EEC syndrome, Arg227Gln TP63 mutation and micturition difficulties: Is there a genotype-phenotype correlation?
|
| Maclean K, Holme SA, Gilmour E, Taylor M, Scheffer H, Graf N, Smith GH, Onikul E, van Bokhoven H, Moss C, Ads LC.
|
| Am J Med Genet A 143(10):1114-9. 2007
|
| 54 | RHS,TP63
|
| Rapp-Hodgkin ectodermal dysplasia syndrome: the clinical and molecular overlap with Hay-Wells syndrome.
|
| Kannu P, Savarirayan R, Ozoemena L, White SM, McGrath JA.
|
| Am J Med Genet A 140(8):887-91. 2006
|
| 55 | TP63
|
| Delineation of the ADULT syndrome phenotype due to arginine 298 mutations of the p63 gene.
|
| Rinne T, Spadoni E, Kjaer KW, Danesino C, Larizza D, Kock M, Huoponen K, Savontaus ML, Aaltonen M, Duijf P, Brunner HG, Penttinen M, van Bokhoven H.
|
| Eur J Hum Genet 14(8):904-10. Epub 2006 May 17. 2006
|
| 56 | ADULT,TP63
|
| Further phenotypic and genetic variation in ADULT syndrome.
|
| Reisler TT, Patton MA, Meagher PP.
|
| Am J Med Genet A 140(22):2495-500. 2006
|
| 57 | TP63
|
| p63 protects the female germ line during meiotic arrest.
|
| Suh EK, Yang A, Kettenbach A, Bamberger C, Michaelis AH, Zhu Z, Elvin JA, Bronson RT, Crum CP, McKeon F.
|
| Nature 444(7119):624-8. Epub 2006 Nov 22. 2006
|
| 58 | TP63
|
| Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells.
|
| Yang A, Zhu Z, Kapranov P, McKeon F, Church GM, Gingeras TR, Struhl K.
|
| Mol Cell 24(4):593-602. 2006
|
| 59 | TP63
|
| p63 overexpression induces the expression of Sonic Hedgehog.
|
| Caserta TM, Kommagani R, Yuan Z, Robbins DJ, Mercer CA, Kadakia MP.
|
| Mol Cancer Res 4(10):759-68. 2006
|
| 60 | GPX2, TP63
|
| GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner.
|
| Yan W, Chen X.
|
| J Biol Chem 281(12):7856-62. Epub 2006 Jan 30. 2006
|
| 61 | TP63
|
| Dysregulation of TAp63 mRNA and protein levels in psoriasis.
|
| Gu X, Lundqvist EN, Coates PJ, Thurfjell N, Wettersand E, Nylander K.
|
| J Invest Dermatol 126(1):137-41. 2006
|
| 62 | TP63, AEC
|
| Two novel TP63 mutations associated with the ankyloblepharon, ectodermal defects, and cleft lip and palate syndrome: a skin fragility phenotype.
|
| Payne AS, Yan AC, Ilyas E, Li W, Seykora JT, Young TL, Pawel BR, Honig PJ, Camacho J, Imaizumi S, Heymann WR, Schnur RE.
|
| Arch Dermatol 141(12):1567-73. 2005
|
| 63 | TP63, AEC
|
| De novo missense mutation, S541Y, in the p63 gene underlying Rapp-Hodgkin ectodermal dysplasia syndrome.
|
| Shotelersuk V, Janklat S, Siriwan P, Tongkobpetch S.
|
| Clin Exp Dermatol 30(3):282-5. 2005
|
| 64 | SSR3, TP63
|
| Copy number changes of target genes in chromosome 3q25.3-qter of esophageal squamous cell carcinoma: TP63 is amplified in early carcinogenesis but down-regulated as disease progressed.
|
| Yen CC, Chen YJ, Pan CC, Lu KH, Chen PC, Hsia JY, Chen JT, Wu YC, Hsu WH, Wang LS, Huang MH, Huang BS, Hu CP, Chen PM, Lin CH.
|
| World J Gastroenterol 11(9):1267-72.
2005
|
| 65 | FOXE1, HTAT, IRF6, MSX1, NECTIN1, OFC2, OFC5, OFC6, OFC6, SATB2, SCD5, TP63
|
| Genetics of cleft lip and palate: syndromic genes contribute to the incidence of non-syndromic clefts.
|
| Stanier P, Moore GE.
|
| Hum Mol Genet 13 Spec No 1:R73-81. Epub 2004 Jan 13. 2004
|
| 66 | ADULT,AEC,RHS,TP63
|
| Molecular evidence that AEC syndrome and Rapp-Hodgkin syndrome are variable expression of a single genetic disorder.
|
| Bertola DR, Kim CA, Albano LM, Scheffer H, Meijer R, van Bokhoven H.
|
| Clin Genet 66(1):79-80. No abstract available. 2004
|
| 67 | TP63, EEC3
|
| TP63 mutation and clefting modifier genes in an EEC syndrome family.
|
| Ray AK, Marazita ML, Pathak R, Beever CL, Cooper ME, Goldstein T, Shaw DF, Field LL.
|
| Clin Genet 66(3):217-22. Erratum in: Clin Genet. 2004 Oct;66(4):373. 2004
|
| 68 | TP63
|
| 63 mutations are not a major cause of non-syndromic split hand/foot malformation.
|
| de Mollerat XJ, Everman DB, Morgan CT, Clarkson KB, Rogers RC, Colby RS, Aylsworth AS, Graham JM Jr, Stevenson RE, Schwartz CE.
|
| J Med Genet 40(1):55-61. No abstract available. 2003
|
| 69 | TP63
|
| Pathogenesis of split-hand/split-foot malformation.
|
| Duijf PH, Van Bokhoven H, Brunner HG.
|
| Hum Mol Genet 12(Suppl 1):R51-60. 2003
|
| 70 | EEC3,TP63
|
| EEC syndrome type 3 with a heterozygous germline mutation in the P63 gene and B cell lymphoma.
|
| Akahoshi K, Sakazume S, Kosaki K, Ohashi H, Fukushima Y.
|
| Am J Med Genet 120A(3):370-3. 2003
|
| 71 | RHS,TP63
|
| The Rapp-Hodgkin syndrome results from mutations of the TP63 gene.
|
| Bougeard G, Hadj-Rabia S, Faivre L, Sarafan-Vasseur N, Frebourg T.
|
| Eur J Hum Genet 11(9):700-4. 2003
|
| 72 | AEC,TP63
|
| A novel p63 sterile alpha motif (SAM) domain mutation in a Japanese patient with ankyloblepharon, ectodermal defects and cleft lip and palate (AEC) syndrome without ankyloblepharon.
|
| Tsutsui K, Asai Y, Fujimoto A, Yamamoto M, Kubo M, Hatta N.
|
| Br J Dermatol 149(2):395-9. 2003
|
| 73 | ADULT,TP63
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| Gain-of-function mutation in ADULT syndrome reveals the presence of a second transactivation domain in p63.
|
| Duijf PH, Vanmolkot KR, Propping P, Friedl W, Krieger E, McKeon F, Dotsch V, Brunner HG, van Bokhoven H.
|
| Hum Mol Genet 11(7):799-804. 2002
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| 74 | TP63
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| The p63 gene in EEC and other syndromes.
|
| Brunner HG, Hamel BC, Van Bokhoven H.
|
| J Med Genet 39(6):377-81. Review. 2002
|
| 75 | AEC,TP63
|
| Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63.
|
| McGrath JA, Duijf PH, Doetsch V, Irvine AD, de Waal R, Vanmolkot KR, Wessagowit V, Kelly A, Atherton DJ, Griffiths WA, Orlow SJ, van Haeringen A, Ausems MG, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BC, van Bokhoven H.
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| Hum Mol Genet 10(3):221-9. 2001
|
| 76 | ADULT,TP63
|
| TP63 gene mutation in ADULT syndrome.
|
| Amiel J, Bougeard G, Francannet C, Raclin V, Munnich A, Lyonnet S, Frebourg T.
|
| Eur J Hum Genet 9(8):642-5. 2001
|
| 77 | TP63
|
| p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.
|
| van Bokhoven H, Hamel BC, Bamshad M, Sangiorgi E, Gurrieri F, Duijf PH, Vanmolkot KR, van Beusekom E, van Beersum SE, Celli J, Merkx GF, Tenconi R, Fryns JP, Verloes A, Newbury-Ecob RA, Raas-Rotschild A, Majewski F, Beemer FA, Janecke A, Chitayat D, Crisponi G, Kayserili H, Yates JR, Neri G, Brunner HG.
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| Am J Hum Genet 69(3):481-92. 2001
|
| 78 | AREL1, CSNK1G2, FMR1, SORBS2, TP63, TUT4
|
| RNA targets of the fragile X protein.
|
| Kaytor MD, Orr HT.
|
| Cell 107(5):555-7. Review. 2001
|
| 79 | TP63
|
| Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51.
|
| Senoo M, Tsuchiya I, Matsumura Y, Mori T, Saito Y, Kato H, Okamoto T, Habu S.
|
| Br J Cancer 84(9):1235-41. 2001
|
| 80 | SHFM4,TP63
|
| Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27.
|
| Ianakiev P, Kilpatrick MW, Toudjarska I, Basel D, Beighton P, Tsipouras P.
|
| Am J Hum Genet 67(1):59-66. 2000
|
| 81 | FGF8,TP63
|
| p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
|
| Yang A, et al.
|
| Nature 398(6729):714-8 1999
|
| 82 | EEC3,TP63
|
| Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome.
|
| Celli J, et al.
|
| Cell 99(2):143-53 1999
|
| 83 | SHFM4,TP63
|
| Mutation and transcription analyses of the p63 gene in cervical carcinoma.
|
| Nishi H, Isaka K, Sagawa Y, Usuda S, Fujito A, Ito H, Senoo M, Kato H, Takayama M.
|
| Int J Oncol 15(6):1149-53. 1999
|
| 84 | TP63
|
| p63 is a p53 homologue required for limb and epidermal morphogenesis.
|
| Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A.
|
| Nature 398(6729):708-13. 1999
|
| 85 | TP63
|
| Cloning and chromosomal mapping of the human p53-related KET gene to chromosome 3q27 and its murine homolog Ket to mouse chromosome 16.
|
| Augustin M, et al.
|
| Mamm Genome 9 : 899-902. 1998
|
| 86 | LMS,TP63
|
| p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
|
| Yang A, et al.
|
| Mol Cell 2(3):305-16 1998
|
| 87 | TP63
|
| A new human p53 homologue.
|
| Trink B, et al.
|
| Nat Med 4(7):747-8. No abstract available 1998
|
| 88 | TP63
|
| Cloning and functional analysis of human p51, which structurally and functionally resembles p53.
|
| Osada M, et al.
|
| Nat Med 4(7):839-43 1998
|
| 89 | TP63
|
| A second p53-related protein, p73L, with high homology to p73.
|
| Senoo M, et al.
|
| Biochem Biophys Res Commun 248(3):603-7 1998
|