| 1 | HEATR3, RPL11, RPL5, TP53
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| Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
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| Hannan KM, Soo P, Wong MS, Lee JK, Hein N, Poh P, Wysoke KD, Williams TD, Montellese C, Smith LK, Al-Obaidi SJ, Núńez-Villacís L, Pavy M, He JS, Parsons KM, Loring KE, Morrison T, Diesch J, Burgio G, Ferreira R, Feng ZP, Gould CM, Madhamshettiwar PB, Flygare J, Gonda TJ, Simpson KJ, Kutay U, Pearson RB, Engel C, Watkins NJ, Hannan RD, George AJ
|
| Cell Rep. Nov 1;41(5):111571. doi: 10.1016/j.celrep.2022.111571 2022
|
| 2 | NEK10, TP53
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| On Broken Ne(c)ks and Broken DNA: The Role of Human NEKs in the DNA Damage Response
|
| Pavan ICB, Peres de Oliveira A, Dias PRF, Basei FL, Issayama LK, Ferezin CC, Silva FR, Rodrigues de Oliveira AL, Alves Dos Reis Moura L, Martins MB, Simabuco FM, Kobarg J.
|
| Cells. Feb 27;10(3):507. doi: 10.3390/cells10030507. 2021
|
| 3 | MDM4, PRPF19, TP53
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| PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA
|
| Yano K, Takahashi RU, Shiotani B, Abe J, Shidooka T, Sudo Y, Yamamoto Y, Kan S, Sakagami H, Tahara H.
|
| J Biol Chem. Jul;297(1):100882. doi: 10.1016/j.jbc.2021.100882. Epub 2021 Jun 16. 2021
|
| 4 | FOXM1, MELK, TP53
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| Mutant P53 induces MELK expression by release of wild-type P53-dependent suppression of FOXM1.
|
| Bollu LR, Shepherd J, Zhao D, Ma Y, Tahaney W, Speers C, Mazumdar A, Mills GB, Brown PH.
|
| NPJ Breast Cancer 6:2. doi: 10.1038/s41523-019-0143-5. eCollection 2020.
2020
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| 5 | TMUB1, TP53
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| HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53-dependent mitochondrial apoptosis
|
| Castelli M, Piobbico D, Chiacchiaretta M, Brunacci C, Pieroni S, Bartoli D, Gargaro M, Fallarino F, Puccetti P, Soddu S, Della-Fazia MA, Servillo G
|
| EMBO Rep. Feb 5;21(2):e48073. doi: 10.15252/embr.201948073. Epub 2019 Dec 23. 2020
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| 6 | NEK10, TP53
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| NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity
|
| Haider N, Dutt P, van de Kooij B, Ho J, Palomero L, Pujana MA, Yaffe M, Stambolic V.
|
| Oncogene. Jul;39(30):5252-5266. doi: 10.1038/s41388-020-1361-x. Epub 2020 Jun 19. 2020
|
| 7 | RBM10, TP53
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| RBM10, a New Regulator of p53
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| Jung JH, Lee H, Zeng SX, Lu H.
|
| Cells. Sep 16;9(9):2107. doi: 10.3390/cells9092107 2020
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| 8 | ATRIP, ETAA1, RAD51, RPA1, TP53
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| Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond. 2020 PMID:
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| Dueva R, Iliakis G.
|
| NAR Cancer. Sep 25;2(3):zcaa022. doi: 10.1093/narcan/zcaa022. 2020
|
| 9 | BMFS6, MDM4, TP53
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| Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance
|
| Toufektchan E, Lejour V, Durand R, Giri N, Draskovic I, Bardot B, Laplante P, Jaber S, Alter BP, Londono-Vallejo JA, Savage SA, Toledo F.
|
| Sci Adv. Apr 10;6(15):eaay3511. doi: 10.1126/sciadv.aay3511. 2020
|
| 10 | CLDN7, TP53
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| The p53-inducible CLDN7 regulates colorectal tumorigenesis and has prognostic significance
|
| Hou Y, Hou L, Liang Y, Zhang Q, Hong X, Wang Y, Huang X, Zhong T, Pang W, Xu C, Zhu L, Li L, Fang J, Meng X.
|
| Neoplasia. Nov;22(11):590-603. doi: 10.1016/j.neo.2020.09.001. Epub 2020 Sep 28. Erratum in: Neoplasia. 2020 Oct 21;22(12):661-662. 2020
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| 11 | TFAM, TIGAR, TP53
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| Down-regulation of TFAM increases the sensitivity of tumour cells to radiation via p53/TIGAR signalling pathway.
|
| Jiang X, Wang J.
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| J Cell Mol Med 23(7):4545-4558. doi: 10.1111/jcmm.14350. Epub 2019 May 6.
2019
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| 12 | HUWE1, LIMCH1, TP53
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| LIMCH1 suppress the growth of lung cancer by interacting with HUWE1 to sustain p53 stability.
|
| Zhang Y, Zhang Y, Xu H.
|
| Gene 712:143963. doi: 10.1016/j.gene.2019.143963. Epub 2019 Jul 5.
2019
|
| 13 | LDHA, TP53
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| p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild-type p53.
|
| Zhou Y, Niu W, Luo Y, Li H, Xie Y, Wang H, Liu Y, Fan S, Li Z, Xiong W, Li X, Ren C, Tan M, Li G, Zhou M.
|
| Cancer Sci 110(3):939-949. doi: 10.1111/cas.13928. Epub 2019 Jan 31.
2019
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| 14 | GLS2, SAT1, SLC7A11, TP53
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| The tumor suppressor protein p53 and the ferroptosis network. 2019
|
| Kang R, Kroemer G, Tang D.
|
| Free Radic Biol Med. 133:162-168. doi: 10.1016/j.freeradbiomed.2018.05.074. Epub 2018 May 23. 2019
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| 15 | EGLN3, TP53
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| Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner
|
| Xu Y, Gao Q, Xue Y, Li X, Xu L, Li C, Qin Y, Fang J.
|
| J Biol Chem. Jun 21;294(25):9949-9958. doi: 10.1074/jbc.RA118.007181. Epub 2019 May 15. 2019
|
| 16 | DKC8, TP53
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| De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.
|
| Toki T, Yoshida K, Wang R, Nakamura S, Maekawa T, Goi K, Katoh MC, Mizuno S, Sugiyama F, Kanezaki R, Uechi T, Nakajima Y, Sato Y, Okuno Y, Sato-Otsubo A, Shiozawa Y, Kataoka K, Shiraishi Y, Sanada M, Chiba K, Tanaka H, Terui K, Sato T, Kamio T, Sakaguchi H, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Kanno H, Miyano S, Kojima S, Ishiguro A, Sugita K, Kenmochi N, Takahashi S, Eto K, Ogawa S, Ito E.
|
| Am J Hum Genet 103(3):440-447. doi: 10.1016/j.ajhg.2018.07.020. Epub 2018 Aug 23.
2018
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| 17 | RSF1, TP53
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| Chromatin-remodeling factor, RSF1, controls p53-mediated transcription in apoptosis upon DNA strand breaks.
|
| Min S, Kim K, Kim SG, Cho H, Lee Y.
|
| Cell Death Dis 9(11):1079. doi: 10.1038/s41419-018-1128-2.
2018
|
| 18 | MDM2, TP53, TRIM65
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| Combinatory inhibition of TRIM65 and MDM2 in lung cancer cells.
|
| Chen G, Zhou T, Liu Y, Yu Z.
|
| Biochem Biophys Res Commun 506(3):698-702. doi: 10.1016/j.bbrc.2018.10.130. Epub 2018 Oct 27.
2018
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| 19 | TIGAR, TP53
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| The diverse role of TIGAR in cellular homeostasis and cancer.
|
| Geng J, Yuan X, Wei M, Wu J, Qin ZH.
|
| Free Radic Res 52(11-12):1240-1249. doi: 10.1080/10715762.2018.1489133. Epub 2018 Oct 4. Review.
2018
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| 20 | OTUD6A, TP53, USP5
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| Ubiquitin-specific peptidase 5 and ovarian tumor deubiquitinase 6A are differentially expressed in p53+/+ and p53-/- HCT116 cells
|
| Kim SY, Kwon SK, Lee SY, Baek KH.
|
| Int J Oncol. May;52(5):1705-1714. doi: 10.3892/ijo.2018.4302. Epub 2018 Mar 5. 2018
|
| 21 | EGLN3, TP53
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| PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359
|
| Rodriguez J, Herrero A, Li S, Rauch N, Quintanilla A, Wynne K, Krstic A, Acosta JC, Taylor C, Schlisio S, von Kriegsheim A.
|
| Cell Rep. Jul 31;24(5):1316-1329. doi: 10.1016/j.celrep.2018.06.108. 2018
|
| 22 | TP53, TRIM45
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| TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination.
|
| Zhang J, Zhang C, Cui J, Ou J, Han J, Qin Y, Zhi F, Wang RF.
|
| Cell Death Dis 8(5):e2831. doi: 10.1038/cddis.2017.149.
2017
|
| 23 | DPP4, TP53
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| The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.
|
| Xie Y, Zhu S, Song X, Sun X, Fan Y, Liu J, Zhong M, Yuan H, Zhang L, Billiar TR, Lotze MT, Zeh HJ 3rd, Kang R, Kroemer G, Tang D.
|
| Cell Rep 20(7):1692-1704. doi: 10.1016/j.celrep.2017.07.055.
2017
|
| 24 | TP53, TRIM71
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| The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation.
|
| Nguyen DTT, Richter D, Michel G, Mitschka S, Kolanus W, Cuevas E, Wulczyn FG.
|
| Cell Death Differ 24(6):1063-1078. doi: 10.1038/cdd.2017.54. Epub 2017 Apr 21.
2017
|
| 25 | FDXR, TP53
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| Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.
|
| Zhang Y, Qian Y, Zhang J, Yan W, Jung YS, Chen M, Huang E, Lloyd K, Duan Y, Wang J, Liu G, Chen X.
|
| Genes Dev enes Dev. 2017 Jul 26. doi: 10.1101/gad.299388.117. [Epub ahead of print]
2017
|
| 26 | RAD21, TP53
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| Mutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells.
|
| Ahn JH, Kim TJ, Lee JH, Choi JH.
|
| Sci Rep 7(1):9076. doi: 10.1038/s41598-017-08880-4.
2017
|
| 27 | CACUL1, TP53
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| CACUL1/CAC1 attenuates p53 activity through PML post-translational modification.
|
| Fukuda T, Kigoshi-Tansho Y, Naganuma T, Kazaana A, Okajima T, Tsuruta F, Chiba T.
|
| Biochem Biophys Res Commun 482(4):863-869. doi: 10.1016/j.bbrc.2016.11.125. Epub 2016 Nov 23.
2017
|
| 28 | DDX3X, TP53
|
| DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression.
|
| Chen WJ, Wang WT, Tsai TY, Li HK, Lee YW.
|
| Sci Rep 7(1):9411. doi: 10.1038/s41598-017-09779-w.
2017
|
| 29 | TP53, VCX
|
| Whole genome sequencing of matched tumor, adjacent non-tumor tissues and corresponding normal blood samples of hepatocellular carcinoma patients revealed dynamic changes of the mutations profiles during hepatocarcinogenesis.
|
| Mao R, Liu J, Liu G, Jin S, Xue Q, Ma L, Fu Y, Zhao N, Xing J, Li L, Qiu Y, Lin B.
|
| Oncotarget Apr 18;8(16):26185-26199. doi: 10.18632/oncotarget.15428 2017
|
| 30 | KDM4B, TP53
|
| KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.
|
| Castellini L, Moon EJ, Razorenova OV, Krieg AJ, von Eyben R, Giaccia AJ.
|
| Nucleic Acids Res. Apr 20;45(7):3674-3692. doi: 10.1093/nar/gkw1281 2017
|
| 31 | SIVA1, STMN1, TP53
|
| Overexpression and Characterization of The C-Terminal Domain of Human Siva1, A Proapoptotic Factor and Cytoskeleton Binding Protein.
|
| Dantas LE, Saad ST, Ramos CH, Bénichou S.
|
| Protein Pept Lett 23(1):43-50.
2016
|
| 32 | BTG2, TP53
|
| Shifting p53-induced senescence to cell death by TIS21(/BTG2/Pc3) gene through posttranslational modification of p53 protein.
|
| Choi OR, Ryu MS, Lim IK.
|
| Cell Signal 28(9):1172-85. doi: 10.1016/j.cellsig.2016.05.014.
2016
|
| 33 | CREBBP, EP300, TP53
|
| Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
|
| Krois AS, Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.
|
| Proc Natl Acad Sci U S A 113(13):E1853-62. doi: 10.1073/pnas.1602487113.
2016
|
| 34 | PPID, TP53
|
| Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells.
|
| Kim SY, Jeong HC, Hong SK, Lee MO, Cho SJ, Cha HJ.
|
| Oncotarget 8(39):64964-64973. doi: 10.18632/oncotarget.11070. eCollection 2017 Sep 12.
2016
|
| 35 | CDKN1A, TGM2, TP53
|
| Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation.
|
| Yeo SY, Itahana Y, Guo AK, Han R, Iwamoto K, Nguyen HT, Bao Y, Kleiber K, Wu YJ, Bay BH, Voorhoeve M, Itahana K.
|
| Elife 5:e07101. doi: 10.7554/eLife.07101.
2016
|
| 36 | BBC3, MYSM1, TP53
|
| Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.
|
| Belle JI, Petrov JC, Langlais D, Robert F, Cencic R, Shen S, Pelletier J, Gros P, Nijnik A.
|
| Cell Death Differ 23(5):759-75. doi: 10.1038/cdd.2015.140. Epub 2016 Jan 15.
2016
|
| 37 | RBPJ, TP53
|
| Negative control of CSL gene transcription by stress/DNA damage response and p53.
|
| Menietti E, Xu X, Ostano P, Joseph JM, Lefort K, Dotto GP.
|
| Cell Cycle 15(13):1767-78. doi: 10.1080/15384101.2016.1186317. Epub 2016 May 10.
2016
|
| 38 | ATRX, MED12, TP53
|
| Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
|
| Mäkinen N, Aavikko M, Heikkinen T, Taipale M, Taipale J, Koivisto-Korander R, Bützow R, Vahteristo P.
|
| PLoS Genet 12(2):e1005850. doi: 10.1371/journal.pgen.1005850. eCollection 2016 Feb.
2016
|
| 39 | CLCA2, MPZL2, TP53, TP63
|
| CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
|
| Ramena G, Yin Y, Yu Y, Walia V, Elble RC.
|
| PLoS One 11(3):e0147489. doi: 10.1371/journal.pone.0147489. eCollection 2016.
2016
|
| 40 | TP53, TRIM65
|
| TRIM65 negatively regulates p53 through ubiquitination.
|
| Li Y, Ma C, Zhou T, Liu Y, Sun L, Yu Z.
|
| Biochem Biophys Res Commun 473(1):278-282. doi: 10.1016/j.bbrc.2016.03.093. Epub 2016 Mar 21.
2016
|
| 41 | PDCD5, TP53
|
| PDCD5 functions as a regulator of p53 dynamics in the DNA damage response.
|
| Zhuge C, Sun X, Chen Y, Lei J.
|
| J Theor Biol 388:1-10. doi: 10.1016/j.jtbi.2015.09.025. Epub 2015 Oct 9. Erratum in: J Theor Biol. 2016 May 7;396:210.
2016
|
| 42 | CDK1, PLK1, TP53
|
| Polo-like kinase 1 inhibits DNA damage response during mitosis.
|
| Benada J, Burdová K, Lidak T, von Morgen P, Macurek L.
|
| Cell Cycle 14(2):219-31. doi: 10.4161/15384101.2014.977067.
2015
|
| 43 | HSP90B1, MDM2, TP53
|
| Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer.
|
| Wu B, Chu X, Feng C, Hou J, Fan H, Liu N, Li C, Kong X, Ye X, Meng S.
|
| Cancer Lett 359(2):325-34. doi: 10.1016/j.canlet.2015.01.034. Epub 2015 Jan 28.
2015
|
| 44 | PATZ1, TP53
|
| PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.
|
| Keskin N, Deniz E, Eryilmaz J, Un M, Batur T, Ersahin T, Cetin Atalay R, Sakaguchi S, Ellmeier W, Erman B.
|
| Mol Cell Biol 35(10):1741-53. doi: 10.1128/MCB.01475-14. Epub 2015 Mar 9.
2015
|
| 45 | PATZ1, TP53
|
| PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration.
|
| Chiappetta G, Valentino T, Vitiello M, Pasquinelli R, Monaco M, Palma G, Sepe R, Luciano A, Pallante P, Palmieri D, Aiello C, Rea D, Losito SN, Arra C, Fusco A, Fedele M.
|
| Oncotarget 6(7):5310-23.
2015
|
| 46 | TP53, YWHAG
|
| p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation.
|
| Chen DY, Dai DF, Hua Y, Qi WQ.
|
| Int J Oncol 46(2):818-24. doi: 10.3892/ijo.2014.2740. Epub 2014 Nov 7.
2015
|
| 47 | SIN3B, TP53
|
| Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes.
|
| Kadamb R, Mittal S, Bansal N, Saluja D.
|
| Biosci Rep 35(4). pii: e00234. doi: 10.1042/BSR20150122.
2015
|
| 48 | KDM8, TP53
|
| JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation.
|
| Huang X, Zhang S, Qi H, Wang Z, Chen HW, Shao J, Shen J.
|
| Biochim Biophys Acta 1853(10 Pt A):2286-95. doi: 10.1016/j.bbamcr.2015.05.026. Epub 2015 May 27.
2015
|
| 49 | PCDH10, TP53
|
| PCDH10, a novel p53 transcriptional target in regulating cell migration.
|
| Shi D, Murty VV, Gu W.
|
| Cell Cycle 14(6):857-66. doi: 10.1080/15384101.2015.1004935.
2015
|
| 50 | SLC2A9, TP53
|
| The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense.
|
| Itahana Y, Han R, Barbier S, Lei Z, Rozen S, Itahana K.
|
| Oncogene 34(14):1799-810. doi: 10.1038/onc.2014.119. Epub 2014 May 26.
2015
|
| 51 | GLI1, GLI2, TAF9, TP53
|
| p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.
|
| Yoon JW, Lamm M, Iannaccone S, Higashiyama N, Leong KF, Iannaccone P, Walterhouse D.
|
| DNA Repair (Amst). Oct;34:9-17. doi: 10.1016/j.dnarep.2015.06.006. Epub 2015 Aug 1 2015
|
| 52 | DDB1, TP53
|
| The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis.
|
| Gao J, Buckley SM, Cimmino L, Guillamot M, Strikoudis A, Cang Y, Goff SP, Aifantis I.
|
| Elife. Nov 27;4:e07539. doi: 10.7554/eLife.07539. 2015
|
| 53 | HINFP, TP53
|
| p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.
|
| Ghule PN, Xie RL, Colby JL, Jones SN, Lian JB, Wijnen AJ, Stein JL, Stein GS.
|
| Cell Cycle. Aug 3;14(15):2501-8. doi: 10.1080/15384101.2015.1049783. Epub 2015 Jun 1. 2015
|
| 54 | MDM2, RBBP6, TP53
|
| The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning
|
| Hull R, Oosthuysen B, Cajee UF, Mokgohloa L, Nweke E, Antunes RJ, Coetzer TH, Ntwasa M.
|
| Int J Mol Sci. May 6;16(5):10242-66. doi: 10.3390/ijms160510242. 2015
|
| 55 | MDM2, NEDD8, TP53, UBE2M
|
| Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase.
|
| Batuello CN, Hauck PM, Gendron JM, Lehman JA, Mayo LD.
|
| Proc Natl Acad Sci U S A. Feb 10;112(6):1749-54. doi: 10.1073/pnas.1416656112. Epub 2015 Jan 26 2015
|
| 56 | MDM2, MDM4, TP53
|
| The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury
|
| Joshi Y, Sória MG, Quadrato G, Inak G, Zhou L, Hervera A, Rathore KI, Elnaggar M, Cucchiarini M, Marine JC, Puttagunta R, Di Giovanni S.
|
| Brain Jul;138(Pt 7):1843-62. doi: 10.1093/brain/awv125. Epub 2015 May 16. Erratum in: Brain. 2016 Jan;139(Pt 1):e7. Magali, Cucchiari 2015
|
| 57 | CDKN1A, RBM24, TP53
|
| Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability.
|
| Jiang Y, Zhang M, Qian Y, Xu E, Zhang J, Chen X.
|
| J Biol Chem 289(6):3164-75. doi: 10.1074/jbc.M113.524413. Epub 2013 Dec 19.
2014
|
| 58 | TP53, TP73
|
| AMPK couples p73 with p53 in cell fate decision.
|
| Adamovich Y, Adler J, Meltser V, Reuven N, Shaul Y.
|
| Cell Death Differ 21(9):1451-9. doi: 10.1038/cdd.2014.60. Epub 2014 May 30.
2014
|
| 59 | TP53, TP73
|
| How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.
|
| Candi E, Agostini M, Melino G, Bernassola F.
|
| Hum Mutat 35(6):702-14. doi: 10.1002/humu.22523. Epub 2014 Mar 7. Review.
2014
|
| 60 | CDKN1A, TOP3A, TP53
|
| DNA topoisomerase III alpha regulates p53-mediated tumor suppression.
|
| Hsieh MY, Fan JR, Chang HW, Chen HC, Shen TL, Teng SC, Yeh YH, Li TK.
|
| Clin Cancer Res 20(6):1489-501. doi: 10.1158/1078-0432.CCR-13-1997. Epub 2014 Feb 13.
2014
|
| 61 | CCNG1, MDM2, NOTCH3, TP53
|
| Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma.
|
| Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, Cescon M, Chieco P, Bolondi L, Gramantieri L.
|
| Oncotarget 5(21):10607-20.
2014
|
| 62 | ISG15, TP53
|
| Isg15 controls p53 stability and functions.
|
| Huang YF, Wee S, Gunaratne J, Lane DP, Bulavin DV.
|
| Cell Cycle 13(14):2200-10. doi: 10.4161/cc.29209. Epub 2014 May 20.
2014
|
| 63 | BCL2L1, TP53
|
| The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
|
| Follis AV, Llambi F, Ou L, Baran K, Green DR, Kriwacki RW.
|
| Nat Struct Mol Biol 21(6):535-43. doi: 10.1038/nsmb.2829. Epub 2014 May 11.
2014
|
| 64 | MDM2, PIAS3, TP53
|
| p53 N‑terminal binding and stabilisation by PIAS3 inhibits MDM2‑induced p53 ubiquitination and regulates cell growth.
|
| Zhao Z, Wu L, Shi H, Wu C.
|
| Mol Med Rep 9(5):1903-8. doi: 10.3892/mmr.2014.1993. Epub 2014 Feb 27.
2014
|
| 65 | PELP1, TP53
|
| Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage response.
|
| Nair BC, Krishnan SR, Sareddy GR, Mann M, Xu B, Natarajan M, Hasty P, Brann D, Tekmal RR, Vadlamudi RK.
|
| Cell Death Differ 21(9):1409-18. doi: 10.1038/cdd.2014.55. Epub 2014 May 2.
2014
|
| 66 | PACS2, SIRT1, TP53
|
| The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.
|
| Atkins KM, Thomas LL, Barroso-González J, Thomas L, Auclair S, Yin J, Kang H, Chung JH, Dikeakos JD, Thomas G.
|
| Cell Rep 8(5):1545-57. doi: 10.1016/j.celrep.2014.07.049. Epub 2014 Aug 21.
2014
|
| 67 | JMJD6, MDM4, TP53
|
| JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
|
| Wang F, He L, Huangyang P, Liang J, Si W, Yan R, Han X, Liu S, Gui B, Li W, Miao D, Jing C, Liu Z, Pei F, Sun L, Shang Y.
|
| PLoS Biol 12(3):e1001819. doi: 10.1371/journal.pbio.1001819. eCollection 2014 Mar.
2014
|
| 68 | TP53, TRIM32
|
| E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.
|
| Liu J, Zhang C, Wang XL, Ly P, Belyi V, Xu-Monette ZY, Young KH, Hu W, Feng Z.
|
| Cell Death Differ 21(11):1792-804. doi: 10.1038/cdd.2014.121. Epub 2014 Aug 22.
2014
|
| 69 | EIF4G2, TP53
|
| The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA.
|
| Weingarten-Gabbay S, Khan D, Liberman N, Yoffe Y, Bialik S, Das S, Oren M, Kimchi A.
|
| Oncogene 33(5):611-8. doi: 10.1038/onc.2012.626. Epub 2013 Jan 14.
2014
|
| 70 | MDM2, TP53, XAF1
|
| XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313.
|
| Lee MG, Han J, Jeong SI, Her NG, Lee JH, Ha TK, Kang MJ, Ryu BK, Chi SG.
|
| Proc Natl Acad Sci U S A 111(43):15532-7. doi: 10.1073/pnas.1411746111. Epub 2014 Oct 13.
2014
|
| 71 | TP53, UNC5D
|
| Unc5D regulates p53-dependent apoptosis in neuroblastoma cells
|
| Wang H, Wu Q, Li S, Zhang B, Chi Z, Hao L.
|
| Mol Med Rep. Jun;9(6):2411-6. doi: 10.3892/mmr.2014.2100. Epub 2014 Apr 1. 2014
|
| 72 | ECD, TP53, TXNIP
|
| TXNIP interacts with hEcd to increase p53 stability and activity.
|
| Suh HW, Yun S, Song H, Jung H, Park YJ, Kim TD, Yoon SR, Choi I.
|
| Biochem Biophys Res Commun 438(2):264-9. doi: 10.1016/j.bbrc.2013.07.036. Epub 2013 Jul 21. 2013
|
| 73 | TP53
|
| The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo.
|
| Hamard PJ, Barthelery N, Hogstad B, Mungamuri SK, Tonnessen CA, Carvajal LA, Senturk E, Gillespie V, Aaronson SA, Merad M, Manfredi JJ.
|
| Genes Dev 27(17):1868-85. doi: 10.1101/gad.224386.113.
2013
|
| 74 | TP53
|
| Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells.
|
| Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, Minamino T, Hirose K, Nakajima H.
|
| J Immunol 191(7):3614-23. doi: 10.4049/jimmunol.1300509. Epub 2013 Sep 4.
2013
|
| 75 | TP53
|
| Activation and control of p53 tetramerization in individual living cells.
|
| Gaglia G, Guan Y, Shah JV, Lahav G.
|
| Proc Natl Acad Sci U S A 110(38):15497-501. doi: 10.1073/pnas.1311126110. Epub 2013 Sep 4.
2013
|
| 76 | RNF38, TP53
|
| RNF38 encodes a nuclear ubiquitin protein ligase that modifies p53.
|
| Sheren JE, Kassenbrock CK.
|
| Biochem Biophys Res Commun 440(4):473-8. doi: 10.1016/j.bbrc.2013.08.031. Epub 2013 Aug 22.
2013
|
| 77 | LGMN, TP53
|
| Transcriptional regulation of the legumain gene by p53 in HCT116 cells.
|
| Yamane T, Murao S, Kato-Ose I, Kashima L, Yuguchi M, Kozuka M, Takeuchi K, Ogita H, Ohkubo I, Ariga H.
|
| Biochem Biophys Res Commun 438(4):613-8. doi: 10.1016/j.bbrc.2013.08.007. Epub 2013 Aug 11.
2013
|
| 78 | EP300, SETD1A, SETD1B, TP53
|
| SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.
|
| Tang Z, Chen WY, Shimada M, Nguyen UT, Kim J, Sun XJ, Sengoku T, McGinty RK, Fernandez JP, Muir TW, Roeder RG.
|
| Cell 154(2):297-310. doi: 10.1016/j.cell.2013.06.027.
2013
|
| 79 | TP53
|
| Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity.
|
| Trinidad AG, Muller PA, Cuellar J, Klejnot M, Nobis M, Valpuesta JM, Vousden KH.
|
| Mol Cell 50(6):805-17. doi: 10.1016/j.molcel.2013.05.002. Epub 2013 Jun 6.
2013
|
| 80 | TGFB1, TP53
|
| Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response.
|
| López-Díaz FJ, Gascard P, Balakrishnan SK, Zhao J, Del Rincon SV, Spruck C, Tlsty TD, Emerson BM.
|
| Mol Cell 50(4):552-64. doi: 10.1016/j.molcel.2013.04.029.
2013
|
| 81 | MIRLET7A1, TP53
|
| Tumor suppressor p53 plays a key role in induction of both tristetraprolin and let-7 in human cancer cells.
|
| Lee JY, Kim HJ, Yoon NA, Lee WH, Min YJ, Ko BK, Lee BJ, Lee A, Cha HJ, Cho WJ, Park JW.
|
| Nucleic Acids Res 41(11):5614-25. doi: 10.1093/nar/gkt222. Epub 2013 Apr 16.
2013
|
| 82 | TP53, VEGFA
|
| p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway.
|
| Farhang Ghahremani M, Goossens S, Nittner D, Bisteau X, Bartunkova S, Zwolinska A, Hulpiau P, Haigh K, Haenebalcke L, Drogat B, Jochemsen A, Roger PP, Marine JC, Haigh JJ.
|
| Cell Death Differ 20(7):888-97. doi: 10.1038/cdd.2013.12. Epub 2013 Mar 1.
2013
|
| 83 | S100A4, TP53
|
| Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts.
|
| Tamaki Y, Iwanaga Y, Niizuma S, Kawashima T, Kato T, Inuzuka Y, Horie T, Morooka H, Takase T, Akahashi Y, Kobuke K, Ono K, Shioi T, Sheikh SP, Ambartsumian N, Lukanidin E, Koshimizu TA, Miyazaki S, Kimura T.
|
| J Mol Cell Cardiol 57:72-81. doi: 10.1016/j.yjmcc.2013.01.007. Epub 2013 Jan 23.
2013
|
| 84 | TP53
|
| A new role of p53 in regulating lipid metabolism.
|
| Wang X, Zhao X, Gao X, Mei Y, Wu M.
|
| J Mol Cell Biol 5(2):147-50. doi: 10.1093/jmcb/mjs064. Epub 2012 Dec 19. No abstract available.
2013
|
| 85 | DNAJC7, MDM2, NR1I3, TP53
|
| Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.
|
| Kubo N, Wu D, Yoshihara Y, Sang M, Nakagawara A, Ozaki T.
|
| Biochem Biophys Res Commun 430(3):1034-9. doi: 10.1016/j.bbrc.2012.11.121. Epub 2012 Dec 21.
2013
|
| 86 | RUNX1, RUNX3, TP53
|
| Runt-related transcription factor 1 (RUNX1) stimulates tumor suppressor p53 protein in response to DNA damage through complex formation and acetylation.
|
| Wu D, Ozaki T, Yoshihara Y, Kubo N, Nakagawara A.
|
| J Biol Chem 288(2):1353-64. doi: 10.1074/jbc.M112.402594. Epub 2012 Nov 12.
2013
|
| 87 | FBL, TP53
|
| p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.
|
| Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzŕlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ.
|
| Cancer Cell 24(3):318-30. doi: 10.1016/j.ccr.2013.08.013.
2013
|
| 88 | BRCA1, CTSL, TP53
|
| BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells.
|
| Grotsky DA, Gonzalez-Suarez I, Novell A, Neumann MA, Yaddanapudi SC, Croke M, Martinez-Alonso M, Redwood AB, Ortega-Martinez S, Feng Z, Lerma E, Ramon y Cajal T, Zhang J, Matias-Guiu X, Dusso A, Gonzalo S.
|
| J Cell Biol 200(2):187-202. doi: 10.1083/jcb.201204053. 2013
|
| 89 | MYBBP1A, TP53
|
| Nucleolar protein, Myb-binding protein 1A, specifically binds to nonacetylated p53 and efficiently promotes transcriptional activation.
|
| Ono W, Akaogi K, Waku T, Kuroda T, Yokoyama W, Hayashi Y, Kimura K, Kishimoto H, Yanagisawa J.
|
| Biochem Biophys Res Commun 434(3):659-63. doi: 10.1016/j.bbrc.2013.04.006. Epub 2013 Apr 11.
2013
|
| 90 | HIST3H3, TAF3, TBP, TP53
|
| H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation.
|
| Lauberth SM, Nakayama T, Wu X, Ferris AL, Tang Z, Hughes SH, Roeder RG.
|
| Cell 152(5):1021-36. doi: 10.1016/j.cell.2013.01.052.
2013
|
| 91 | KAT6A, PML, TP53
|
| MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
|
| Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C.
|
| Proc Natl Acad Sci U S A 110(10):3895-900. doi: 10.1073/pnas.1300490110. Epub 2013 Feb 19.
2013
|
| 92 | RPA1, TP53
|
| A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A.
|
| Glanzer JG, Carnes KA, Soto P, Liu S, Parkhurst LJ, Oakley GG.
|
| Nucleic Acids Res 41(3):2047-59. doi: 10.1093/nar/gks1291. Epub 2012 Dec 24.
2013
|
| 93 | TP53, ZNF365
|
| ZNF365 promotes stability of fragile sites and telomeres.
|
| Zhang Y, Shin SJ, Liu D, Ivanova E, Foerster F, Ying H, Zheng H, Xiao Y, Chen Z, Protopopov A, Depinho RA, Paik JH.
|
| Cancer Discov 3(7):798-811. doi: 10.1158/2159-8290.CD-12-0536. Epub 2013 Jun 17.
2013
|
| 94 | TP53
|
| Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.
|
| Wang X, Zha M, Zhao X, Jiang P, Du W, Tam AY, Mei Y, Wu M.
|
| Nat Commun 4:1551. doi: 10.1038/ncomms2533.
2013
|
| 95 | SIVA1, TP53
|
| Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.
|
| Wang X, Zha M, Zhao X, Jiang P, Du W, Tam AY, Mei Y, Wu M.
|
| Nat Commun 4:1551. doi: 10.1038/ncomms2533.
2013
|
| 96 | BRCA2, TP53
|
| p53 suppresses BRCA2-stimulated ATPase and strand exchange functions of human RAD51.
|
| Verma S, Rao BJ.
|
| J Biochem 154(3):237-48. doi: 10.1093/jb/mvt040.
2013
|
| 97 | KIF23, TP53
|
| p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.
|
| Fischer M, Grundke I, Sohr S, Quaas M, Hoffmann S, Knörck A, Gumhold C, Rother K.
|
| PLoS One 8(5):e63187. doi: 10.1371/journal.pone.0063187.
2013
|
| 98 | CHCHD4, TP53
|
| Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity.
|
| Zhuang J, Wang PY, Huang X, Chen X, Kang JG, Hwang PM.
|
| Proc Natl Acad Sci U S A 110(43):17356-61. doi: 10.1073/pnas.1310908110. Epub 2013 Oct 7.
2013
|
| 99 | OTUD5, TP53
|
| OTUD5 regulates p53 stability by deubiquitinating p53
|
| Luo J, Lu Z, Lu X, Chen L, Cao J, Zhang S, Ling Y, Zhou X.
|
| PLoS One. Oct 15;8(10):e77682. doi: 10.1371/journal.pone.0077682. 2013
|
| 100 | MDM2, RPL11, TP53
|
| Physical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF.
|
| Dai MS, Challagundla KB, Sun XX, Palam LR, Zeng SX, Wek RC, Lu H.
|
| J Biol Chem 287(21):17120-9. Epub 2012 Mar 30.
2012
|
| 101 | NCL, RPL26, TP53
|
| Interactions of nucleolin and ribosomal protein L26 (RPL26) in translational control of human p53 mRNA.
|
| Chen J, Guo K, Kastan MB.
|
| J Biol Chem 287(20):16467-76. doi: 10.1074/jbc.M112.349274. Epub 2012 Mar 20.
2012
|
| 102 | SP1, TP53
|
| Transcription factors TP53 and SP1 and the osteogenic differentiation of dental stem cells.
|
| Felthaus O, Viale-Bouroncle S, Driemel O, Reichert TE, Schmalz G, Morsczeck C.
|
| Differentiation 83(1):10-6. doi: 10.1016/j.diff.2011.08.008. Epub 2011 Oct 4. Erratum in: Differentiation. 2012 Apr;83(4):231. Oliver, Felthaus 2012
|
| 103 | ARID3A, CDKN1A, TP53
|
| Cooperation between ARID3A and p53 in the transcriptional activation of p21WAF1 in response to DNA damage.
|
| Lestari W, Ichwan SJ, Otsu M, Yamada S, Iseki S, Shimizu S, Ikeda MA.
|
| Biochem Biophys Res Commun 417(2):710-6. doi: 10.1016/j.bbrc.2011.12.003. Epub 2011 Dec 8.
2012
|
| 104 | RECQL4, TP53
|
| RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress.
|
| De S, Kumari J, Mudgal R, Modi P, Gupta S, Futami K, Goto H, Lindor NM, Furuichi Y, Mohanty D, Sengupta S.
|
| J Cell Sci 125(Pt 10):2509-22. doi: 10.1242/jcs.101501. Epub 2012 Feb 22.
2012
|
| 105 | PRAP1, TP53
|
| PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage.
|
| Huang BH, Zhuo JL, Leung CH, Lu GD, Liu JJ, Yap CT, Hooi SC.
|
| Cell Death Dis 3:e442. doi: 10.1038/cddis.2012.180.
2012
|
| 106 | CREBZF, TP53
|
| The transcription factor CREBZF is a novel positive regulator of p53.
|
| López-Mateo I, Villaronga MÁ, Llanos S, Belandia B.
|
| Cell Cycle 11(20):3887-95. doi: 10.4161/cc.22133. Epub 2012 Sep 14.
2012
|
| 107 | HEXIM1, TP53
|
| Identification of HEXIM1 as a positive regulator of p53.
|
| Lew QJ, Chia YL, Chu KL, Lam YT, Gurumurthy M, Xu S, Lam KP, Cheong N, Chao SH.
|
| J Biol Chem 287(43):36443-54. doi: 10.1074/jbc.M112.374157. Epub 2012 Sep 4.
2012
|
| 108 | PHF20, TP53
|
| PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
|
| Cui G, Park S, Badeaux AI, Kim D, Lee J, Thompson JR, Yan F, Kaneko S, Yuan Z, Botuyan MV, Bedford MT, Cheng JQ, Mer G.
|
| Nat Struct Mol Biol 19(9):916-24. doi: 10.1038/nsmb.2353. Epub 2012 Aug 5.
2012
|
| 109 | CCL2, TP53
|
| p53 is an important regulator of CCL2 gene expression.
|
| Tang X, Asano M, O'Reilly A, Farquhar A, Yang Y, Amar S.
|
| Curr Mol Med 12(8):929-43.
2012
|
| 110 | E2F7, TP53
|
| E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression.
|
| Carvajal LA, Hamard PJ, Tonnessen C, Manfredi JJ.
|
| Genes Dev 26(14):1533-45. doi: 10.1101/gad.184911.111.
2012
|
| 111 | MDM2, TP53
|
| Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stability.
|
| Dolezelova P, Cetkovska K, Vousden KH, Uldrijan S.
|
| FEBS Lett 586(16):2225-31. doi: 10.1016/j.febslet.2012.05.034. Epub 2012 May 31.
2012
|
| 112 | AURKB, TP53
|
| Aurora B kinase phosphorylates and instigates degradation of p53.
|
| Gully CP, Velazquez-Torres G, Shin JH, Fuentes-Mattei E, Wang E, Carlock C, Chen J, Rothenberg D, Adams HP, Choi HH, Guma S, Phan L, Chou PC, Su CH, Zhang F, Chen JS, Yang TY, Yeung SC, Lee MH.
|
| Proc Natl Acad Sci U S A 109(24):E1513-22. doi: 10.1073/pnas.1110287109. Epub 2012 May 18.
2012
|
| 113 | ESR1, TP53
|
| p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.
|
| Berger CE, Qian Y, Liu G, Chen H, Chen X.
|
| J Biol Chem 287(36):30117-27. doi: 10.1074/jbc.M112.367326. Epub 2012 Jul 11.
2012
|
| 114 | ATG7, CDKN1A, TP53
|
| Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.
|
| Lee IH, Kawai Y, Fergusson MM, Rovira II, Bishop AJ, Motoyama N, Cao L, Finkel T.
|
| Science 336(6078):225-8. doi: 10.1126/science.1218395. Erratum in: Science. 2013 Aug 2;341(6145):457. Science. 2012 Aug 24;337(6097):911 2012
|
| 115 | E2F1, TP53
|
| Inhibitory role of E2F-1 in the regulation of tumor suppressor p53 during DNA damage response.
|
| Yoshihara Y, Wu D, Kubo N, Sang M, Nakagawara A, Ozaki T.
|
| Biochem Biophys Res Commun 421(1):57-63. doi: 10.1016/j.bbrc.2012.03.108. Epub 2012 Mar 29.
2012
|
| 116 | NLRP10, TP53
|
| Functional characterization of the p53 binding site in the human PYNOD promoter.
|
| Zeng Q, Lu D, Tang Q, Tian L, Wang H, Tang S, Hu C.
|
| Hum Immunol 73(4):355-63. doi: 10.1016/j.humimm.2012.01.010. Epub 2012 Feb 10.
2012
|
| 117 | ATF3, TP53
|
| Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.
|
| Taketani K, Kawauchi J, Tanaka-Okamoto M, Ishizaki H, Tanaka Y, Sakai T, Miyoshi J, Maehara Y, Kitajima S.
|
| Oncogene 31(17):2210-21. doi: 10.1038/onc.2011.397. Epub 2011 Sep 19.
2012
|
| 118 | TP53, UBR5
|
| EDD induces cell cycle arrest by increasing p53 levels.
|
| Smits VA.
|
| Cell Cycle 11(4):715-20. doi: 10.4161/cc.11.4.19154.
2012
|
| 119 | MAF, PROX1, TP53
|
| The tumor suppressor p53 regulates c-Maf and Prox-1 to control lens differentiation.
|
| Liu FY, Tang XC, Deng M, Chen P, Ji W, Zhang X, Gong L, Woodward Z, Liu J, Zhang L, Sun S, Liu JP, Wu K, Wu MX, Liu XL, Yu MB, Liu Y, Li DW.
|
| Curr Mol Med 12(8):917-28.
2012
|
| 120 | SH2D1A, TP53
|
| p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP.
|
| Madapura HS, Salamon D, Wiman KG, Lain S, Klein G, Klein E, Nagy N.
|
| Cell Cycle 11(24):4563-9. doi: 10.4161/cc.22810. Epub 2012 Nov 19.
2012
|
| 121 | PDK2, TP53
|
| p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2.
|
| Contractor T, Harris CR.
|
| Cancer Res 72(2):560-7. doi: 10.1158/0008-5472.CAN-11-1215. Epub 2011 Nov 28.
2012
|
| 122 | FOXO1, NDN, SIRT1, TP53
|
| Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.
|
| Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K.
|
| J Neurosci 32(16):5562-72. doi: 10.1523/JNEUROSCI.0142-12.2012.
2012
|
| 123 | BBC3, PMAIP1, TP53, TP63
|
| DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa.
|
| Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, Strasser A.
|
| Mol Cell 48(3):343-52. doi: 10.1016/j.molcel.2012.08.017. Epub 2012 Sep 20.
2012
|
| 124 | MTA1, TP53
|
| Poly(ADP-ribosyl)ation of p53 induces gene-specific transcriptional repression of MTA1.
|
| Lee MH, Na H, Kim EJ, Lee HW, Lee MO.
|
| Oncogene 31(49):5099-107. doi: 10.1038/onc.2012.2. Epub 2012 Jan 30.
2012
|
| 125 | TP53, XAF1
|
| XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification.
|
| Zou B, Chim CS, Pang R, Zeng H, Dai Y, Zhang R, Lam CS, Tan VP, Hung IF, Lan HY, Wong BC.
|
| Mol Carcinog 51(5):422-32. doi: 10.1002/mc.20807. Epub 2011 Jun 15.
2012
|
| 126 | MDM2, SENP3, TP53
|
| The nucleolar SUMO-specific protease SMT3IP1/SENP3 attenuates Mdm2-mediated p53 ubiquitination and degradation.
|
| Nishida T, Yamada Y.
|
| Biochem Biophys Res Commun 406(2):285-91. Epub 2011 Feb 18.
2011
|
| 127 | KIT, MKI67, TP53
|
| CD117, Ki-67, and p53 predict survival in neuroendocrine carcinomas, but not within the subgroup of small cell lung carcinoma.
|
| Erler BS, Presby MM, Finch M, Hodges A, Horowitz K, Topilow AA, Matulewicz T.
|
| Tumour Biol 32(1):107-11. Epub 2010 Nov 8.
2011
|
| 128 | AXIN1, PML, TP53
|
| AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation.
|
| Li Q, He Y, Wei L, Wu X, Wu D, Lin S, Wang Z, Ye Z, Lin SC.
|
| Oncogene 30(10):1194-204. Epub 2010 Nov 8.
2011
|
| 129 | NOTCH4, TP53
|
| Trp53 regulates Notch 4 signaling through Mdm2.
|
| Sun Y, Klauzinska M, Lake RJ, Lee JM, Santopietro S, Raafat A, Salomon D, Callahan R, Artavanis-Tsakonas S.
|
| J Cell Sci 124(Pt 7):1067-76.
2011
|
| 130 | PRKN, TIGAR, TP53
|
| Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect.
|
| Zhang C, Lin M, Wu R, Wang X, Yang B, Levine AJ, Hu W, Feng Z.
|
| Proc Natl Acad Sci U S A 108(39):16259-64. Epub 2011 Sep 19. 2011
|
| 131 | TP53
|
| A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
|
| Stacey SN, Sulem P, Jonasdottir A, Masson G, Gudmundsson J, Gudbjartsson DF, Magnusson OT, Gudjonsson SA, Sigurgeirsson B, Thorisdottir K, Ragnarsson R, Benediktsdottir KR, Nexř BA, Tjřnneland A, Overvad K, Rudnai P, Gurzau E, Koppova K, Hemminki K, Corredera C, Fuentelsaz V, Grasa P, Navarrete S, Fuertes F, García-Prats MD, Sanambrosio E, Panadero A, De Juan A, Garcia A, Rivera F, Planelles D, Soriano V, Requena C, Aben KK, van Rossum MM, Cremers RG, van Oort IM, van Spronsen DJ, Schalken JA, Peters WH, Helfand BT, Donovan JL, Hamdy FC, Badescu D, Codreanu O, Jinga M, Csiki IE, Constantinescu V, Badea P, Mates IN, Dinu DE, Constantin A, Mates D, Kristjansdottir S, Agnarsson BA, Jonsson E, Barkardottir RB, Einarsson GV, Sigurdsson F, Moller PH, Stefansson T, Valdimarsson T, Johannsson OT, Sigurdsson H, Jonsson T, Jonasson JG, Tryggvadottir L, Rice T, Hansen HM, Xiao Y, Lachance DH, O Neill BP, Kosel ML, Decker PA, Thorleifsson G, Johannsdottir H, Helgadottir HT, Sigurdsson A, Steinthorsdottir V, Lindblom A; Swedish Low-risk Colorectal Cancer Study Group, Sandler RS, Keku TO, Banasik K, Jřrgensen T, Witte DR, Hansen T, Pedersen O, Jinga V, Neal DE, Catalona WJ, Wrensch M, Wiencke J, Jenkins RB, Nagore E, Vogel U, Kiemeney LA, Kumar R, Mayordomo JI, Olafsson JH, Kong A, Thorsteinsdottir U, Rafnar T, Stefansson K.
|
| Nat Genet 43(11):1098-103. doi: 10.1038/ng.926.
2011
|
| 132 | BARD1, BRCA1, BRCA2, BRIP1, CHEK2, MRE11A, MSH6, NBN, PALB2, RAD50, RAD51c, TP53
|
| Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
|
| Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM, Roeb W, Agnew KJ, Stray SM, Wickramanayake A, Norquist B, Pennington KP, Garcia RL, King MC, Swisher EM.
|
| Proc Natl Acad Sci U S A 108(44):18032-7. doi: 10.1073/pnas.1115052108. Epub 2011 Oct 17.
2011
|
| 133 | TP53
|
| Acquisition of p53 mutations in response to the non-genotoxic p53 activator Nutlin-3.
|
| Aziz MH, Shen H, Maki CG.
|
| Oncogene 30(46):4678-86. doi: 10.1038/onc.2011.185. Epub 2011 Jun 6.
2011
|
| 134 | BAIAP2L1, MDM2, TP53
|
| Insulin receptor tyrosine kinase substrate enhances low levels of MDM2-mediated p53 ubiquitination.
|
| Wang KS, Chen G, Shen HL, Li TT, Chen F, Wang QW, Wang ZQ, Han ZG, Zhang X.
|
| PLoS One 6(8):e23571. doi: 10.1371/journal.pone.0023571. Epub 2011 Aug 24.
2011
|
| 135 | RBCC1, TP53
|
| p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.
|
| Morselli E, Shen S, Ruckenstuhl C, Bauer MA, Marińo G, Galluzzi L, Criollo A, Michaud M, Maiuri MC, Chano T, Madeo F, Kroemer G.
|
| Cell Cycle 10(16):2763-9. Epub 2011 Aug 15.
2011
|
| 136 | TP53, UBR5
|
| EDD inhibits ATM-mediated phosphorylation of p53.
|
| Ling S, Lin WC.
|
| J Biol Chem 286(17):14972-82. doi: 10.1074/jbc.M110.182527. Epub 2011 Mar 7.
2011
|
| 137 | TP53, WDR74
|
| Wdr74 is required for blastocyst formation in the mouse.
|
| Maserati M, Walentuk M, Dai X, Holston O, Adams D, Mager J.
|
| PLoS One. 6(7):e22516. doi: 10.1371/journal.pone.0022516. Epub 2011 Jul 25. 2011
|
| 138 | TP53, USP10
|
| USP10 regulates p53 localization and stability by deubiquitinating p53.
|
| Yuan J, Luo K, Zhang L, Cheville JC, Lou Z.
|
| Cell 140(3):384-96. Epub 2010 Jan 21.
2010
|
| 139 | LMO3, TP53
|
| LMO3 interacts with p53 and inhibits its transcriptional activity.
|
| Larsen S, Yokochi T, Isogai E, Nakamura Y, Ozaki T, Nakagawara A.
|
| Biochem Biophys Res Commun 392(3):252-7. Epub 2009 Dec 6.
2010
|
| 140 | PHB, SKP2, TP53
|
| Skp2B attenuates p53 function by inhibiting prohibitin.
|
| Chander H, Halpern M, Resnick-Silverman L, Manfredi JJ, Germain D.
|
| EMBO Rep 11(3):220-5. Epub 2010 Feb 5.
2010
|
| 141 | DNAJA3, TP53
|
| Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer.
|
| Ahn BY, Trinh DL, Zajchowski LD, Lee B, Elwi AN, Kim SW.
|
| Oncogene 29(8):1155-66. Epub 2009 Nov 23.
2010
|
| 142 | CCDC106, TP53
|
| Identification and characterization of the novel protein CCDC106 that interacts with p53 and promotes its degradation.
|
| Zhou J, Qiao X, Xiao L, Sun W, Wang L, Li H, Wu Y, Ding X, Hu X, Zhou C, Zhang J.
|
| FEBS Lett 584(6):1085-90. Epub 2010 Feb 14.PMID: 20159018 2010
|
| 143 | DEL17P131, TP53
|
| 17p13.1 microdeletion involving the TP53 gene in a boy presenting with mental retardation but no tumor.
|
| Schluth-Bolard C, Sanlaville D, Labalme A, Till M, Morin I, Touraine R, Edery P.
|
| Am J Med Genet A 152A(5):1278-82.PMID: 20425836 2010
|
| 144 | NEDD8, NUB1, TP53
|
| NUB1 promotes cytoplasmic localization of p53 through cooperation of the NEDD8 and ubiquitin pathways.
|
| Liu G, Xirodimas DP.
|
| Oncogene 29(15):2252-61. Epub 2010 Jan 25.PMID: 20101219 2010
|
| 145 | MYCN, TP53
|
| p53 is a direct transcriptional target of MYCN in neuroblastoma.
|
| Chen L, Iraci N, Gherardi S, Gamble LD, Wood KM, Perini G, Lunec J, Tweddle DA.
|
| Cancer Res 70(4):1377-88. Epub 2010 Feb 9.
2010
|
| 146 | RUNX3, TP53
|
| RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.
|
| Yamada C, Ozaki T, Ando K, Suenaga Y, Inoue K, Ito Y, Okoshi R, Kageyama H, Kimura H, Miyazaki M, Nakagawara A.
|
| J Biol Chem 285(22):16693-703. Epub 2010 Mar 30.
2010
|
| 147 | BRCA2, TP53
|
| Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2.
|
| Rajagopalan S, Andreeva A, Rutherford TJ, Fersht AR.
|
| Proc Natl Acad Sci U S A 107(19):8587-92. Epub 2010 Apr 26.PMID: 20421506 2010
|
| 148 | DHRS2, MDM2, MYB, TP53
|
| Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
|
| Deisenroth C, Thorner AR, Enomoto T, Perou CM, Zhang Y.
|
| Mol Cell Biol 30(16):3981-93. Epub 2010 Jun 14.PMID: 20547751 2010
|
| 149 | DEL17P131, TP53
|
| A common molecular mechanism underlies two phenotypically distinct 17p13.1 microdeletion syndromes.
|
| Shlien A, Baskin B, Achatz MI, Stavropoulos DJ, Nichols KE, Hudgins L, Morel CF, Adam MP, Zhukova N, Rotin L, Novokmet A, Druker H, Shago M, Ray PN, Hainaut P, Malkin D.
|
| Am J Hum Genet 87(5):631-42.PMID: 21056402 2010
|
| 150 | TP53
|
| Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations.
|
| Barekati Z, Radpour R, Kohler C, Zhang B, Toniolo P, Lenner P, Lv Q, Zheng H, Zhong XY.
|
| Hum Mol Genet 19(15):2936-46. Epub 2010 May 12.PMID: 20466735 2010
|
| 151 | MDM2, TP53
|
| The C terminus of p53 binds the N-terminal domain of MDM2.
|
| Poyurovsky MV, Katz C, Laptenko O, Beckerman R, Lokshin M, Ahn J, Byeon IJ, Gabizon R, Mattia M, Zupnick A, Brown LM, Friedler A, Prives C.
|
| Nat Struct Mol Biol 17(8):982-9. Epub 2010 Jul 18.
2010
|
| 152 | BBC3, TP53
|
| Puma is required for p53-induced depletion of adult stem cells.
|
| Liu D, Ou L, Clemenson GD Jr, Chao C, Lutske ME, Zambetti GP, Gage FH, Xu Y.
|
| Nat Cell Biol 12(10):993-8. Epub 2010 Sep 5.
2010
|
| 153 | TP53
|
| PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells.
|
| Russo D, Ottaggio L, Penna I, Foggetti G, Fronza G, Inga A, Menichini P.
|
| Biochem Biophys Res Commun 402(2):345-50. Epub 2010 Oct 12.
2010
|
| 154 | TP53, TP63
|
| TAp63 plays compensatory roles in p53-deficient cancer cells under genotoxic stress.
|
| Yao JY, Chen JK.
|
| Biochem Biophys Res Commun 403(3-4):310-5. Epub 2010 Nov 12.
2010
|
| 155 | MKI67, TP53
|
| Immunohistochemical study of p53 and Ki67 in a group of patients with mammary carcinoma.
|
| Pleşan DM, Georgescu CV, Pătrană N, Pleşan C, Stoica D.
|
| Rom J Morphol Embryol 51(3):459-65.
2010
|
| 156 | CERS5, HMGB1, TCF3, TP53, TRIM28, ZNF346
|
| Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer.
|
| Kijanka G, Hector S, Kay EW, Murray F, Cummins R, Murphy D, MacCraith BD, Prehn JH, Kenny D.
|
| Gut 59(1):69-78. Epub . 2010
|
| 157 | TP53, UNC5A
|
| Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis
|
| Miyamoto Y, Futamura M, Kitamura N, Nakamura Y, Baba H, Arakawa H.
|
| Int J Oncol. May;36(5):1253-60. doi: 10.3892/ijo_00000609 2010
|
| 158 | TP53, WRAP53
|
| Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage.
|
| Mahmoudi S, Henriksson S, Corcoran M, Méndez-Vidal C, Wiman KG, Farnebo M.
|
| Mol Cell 33(4):462-71.
2009
|
| 159 | TP53, WRAP53
|
| A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.
|
| Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE.
|
| Science 323(5914):644-8. 2009
|
| 160 | PHLDA3, TP53
|
| PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.
|
| Kawase T, Ohki R, Shibata T, Tsutsumi S, Kamimura N, Inazawa J, Ohta T, Ichikawa H, Aburatani H, Tashiro F, Taya Y.
|
| Cell 136(3):535-50.
2009
|
| 161 | CDKN1A, SP1, TP53, ZBTB2
|
| ZBTB2, a Novel Master Regulator of the p53 Pathway.
|
| Jeon BN, Choi WI, Yu MY, Yoon AR, Kim MH, Yun CO, Hur MW.
|
| J Biol Chem 284(27):17935-46. Epub 2009 Apr 20.
2009
|
| 162 | SMARCA4, TP53
|
| The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.
|
| Naidu SR, Love IM, Imbalzano AN, Grossman SR, Androphy EJ.
|
| Oncogene 28(27):2492-501. Epub 2009 May 18.
2009
|
| 163 | TOE1, TP53
|
| TOE1 interacts with p53 to modulate its transactivation potential.
|
| Sperandio S, Tardito S, Surzycki A, Latterich M, de Belle I.
|
| FEBS Lett 583(13):2165-70. Epub 2009 Jun 7. 2009
|
| 164 | BCL2, MDM4, TP53
|
| MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway.
|
| Mancini F, Di Conza G, Pellegrino M, Rinaldo C, Prodosmo A, Giglio S, D'Agnano I, Florenzano F, Felicioni L, Buttitta F, Marchetti A, Sacchi A, Pontecorvi A, Soddu S, Moretti F.
|
| EMBO J 28(13):1926-39. Epub 2009 Jun 11.
2009
|
| 165 | PKLR, TP53
|
| PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53.
|
| Yoon CH, Lee ES, Lim DS, Bae YS.
|
| Proc Natl Acad Sci U S A 106(19):7852-7. Epub 2009 Apr 24.
2009
|
| 166 | S100A9, TP53
|
| A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway.
|
| Li C, Chen H, Ding F, Zhang Y, Luo A, Wang M, Liu Z.
|
| Biochem J 422(2):363-72. 2009
|
| 167 | FAS, TP53, TP63, TP73
|
| Active transcription of the human FAS/CD95/TNFRSF6 gene involves the p53 family.
|
| Schilling T, Schleithoff ES, Kairat A, Melino G, Stremmel W, Oren M, Krammer PH, Müller M.
|
| Biochem Biophys Res Commun 387(2):399-404. Epub 2009 Jul 16.
2009
|
| 168 | EIF4E, PRMT5, TP53
|
| PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.
|
| Scoumanne A, Zhang J, Chen X.
|
| Nucleic Acids Res 37(15):4965-76. Epub 2009 Jun 15.
2009
|
| 169 | TP53, TRIM24
|
| Trim24 targets endogenous p53 for degradation.
|
| Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton MC.
|
| Proc Natl Acad Sci U S A 106(28):11612-6. Epub 2009 Jun 25.
2009
|
| 170 | CABIN1, TP53
|
| Cabin1 restrains p53 activity on chromatin.
|
| Jang H, Choi SY, Cho EJ, Youn HD.
|
| Nat Struct Mol Biol 16(9):910-5. Epub 2009 Aug 9.PMID: 19668210 2009
|
| 171 | RREB1, TP53
|
| DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter.
|
| Liu H, Hew HC, Lu ZG, Yamaguchi T, Miki Y, Yoshida K.
|
| Biochem J 422(3):543-51. 2009
|
| 172 | MDM2, SIVA1, TP53
|
| Suppression of p53 activity by Siva1.
|
| Du W, Jiang P, Li N, Mei Y, Wang X, Wen L, Yang X, Wu M.
|
| Cell Death Differ 16(11):1493-504. Epub 2009 Jul 10.PMID: 19590512 2009
|
| 173 | PECAM1, TP53
|
| Significance of p53 and CD31 in astrogliomas.
|
| Khattab AZ, Ahmed MI, Fouad MA, Essa WA.
|
| Med Oncol 26(1):86-92. Epub 2008 Sep 20.PMID: 18821037 2009
|
| 174 | FOXM1, TP53
|
| Pro-proliferative FoxM1 is a target of p53-mediated repression.
|
| Barsotti AM, Prives C.
|
| Oncogene 28(48):4295-305. Epub 2009 Sep 14.PMID: 19749794 2009
|
| 175 | TFAM, TP53
|
| Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.
|
| Wong TS, Rajagopalan S, Freund SM, Rutherford TJ, Andreeva A, Townsley FM, Petrovich M, Fersht AR.
|
| Nucleic Acids Res 37(20):6765-83. Epub 2009 Sep 15.PMID: 19755502 2009
|
| 176 | DEL17P131, DLG4, GABARAP, GPS2, KCTD11, TP53
|
| Constitutional haploinsufficiency of tumor suppressor genes in mentally retarded patients with microdeletions in 17p13.1.
|
| Krepischi-Santos AC, Rajan D, Temple IK, Shrubb V, Crolla JA, Huang S, Beal S, Otto PA, Carter NP, Vianna-Morgante AM, Rosenberg C.
|
| Cytogenet Genome Res 125(1):1-7. Epub 2009 Jul 14. 2009
|
| 177 | TOPBP1, TP53
|
| Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer.
|
| Liu K, Bellam N, Lin HY, Wang B, Stockard CR, Grizzle WE, Lin WC.
|
| Mol Cell Biol 29(10):2673-93. Epub 2009 Mar 16.PMID: 19289498 2009
|
| 178 | DEL17P131, TP53
|
| Clinical utility of array comparative genomic hybridization: uncovering tumor susceptibility in individuals with developmental delay.
|
| Adam MP, Justice AN, Schelley S, Kwan A, Hudgins L, Martin CL.
|
| J Pediatr 154(1):143-6.PMID: 19187739 2009
|
| 179 | ATP5A1, TP53
|
| The putative tumour modifier gene ATP5A1 is not mutated in human colorectal cancer cell lines but expression levels correlate with TP53 mutations and chromosomal instability.
|
| Seth R, Keeley J, Abu-Ali G, Crook S, Jackson D, Ilyas M.
|
| J Clin Pathol 62(7):598-603. Epub 2009 Mar 3.
2009
|
| 180 | MKI67, TP53
|
| Expression of P27, Ki67 and P53 in squamous cell carcinoma, actinic keratosis and Bowen disease.
|
| Talghini S, Halimi M, Baybordi H.
|
| Pak J Biol Sci 12(12):929-33.
2009
|
| 181 | TP53, WRAP53
|
| Wrap53, a novel regulator of p53.
|
| Farnebo M.
|
| Cell Cycle 8(15):2343-6. Epub 2009 Aug 8.
2009
|
| 182 | GZMK, TP53
|
| Ignition of p53 bomb sensitizes tumor cells to granzyme K-mediated cytolysis.
|
| Hua G, Wang S, Zhong C, Xue P, Fan Z.
|
| J Immunol 182(4):2152-9.
2009
|
| 183 | BCAS2, TP53
|
| Breast cancer amplified sequence 2, a novel negative regulator of the p53 tumor suppressor.
|
| Kuo PC, Tsao YP, Chang HW, Chen PH, Huang CW, Lin ST, Weng YT, Tsai TC, Shieh SY, Chen SL.
|
| Cancer Res 69(23):8877-85. doi: 10.1158/0008-5472.CAN-09-2023. Epub 2009 Nov 10.
2009
|
| 184 | PPP1R13B, TP53, TP53BP2, TP63, TP73
|
| Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.
|
| Patel S, George R, Autore F, Fraternali F, Ladbury JE, Nikolova PV.
|
| Nucleic Acids Res 36(16):5139-51. Epub 2008 Aug 2.
2008
|
| 185 | STX6, TP53
|
| Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival.
|
| Zhang Y, Shu L, Chen X.
|
| J Biol Chem 283(45):30689-98. Epub 2008 Sep 8.
2008
|
| 186 | PSRC1, TP53
|
| Human DDA3 is an oncoprotein down-regulated by p53 and DNA damage.
|
| Hsieh WJ, Hsieh SC, Chen CC, Wang FF.
|
| Biochem Biophys Res Commun 369(2):567-72. Epub 2008 Feb 20. 2008
|
| 187 | SMARCD1, TP53
|
| BAF60a interacts with p53 to recruit the SWI/SNF complex.
|
| Oh J, Sohn DH, Ko M, Chung H, Jeon SH, Seong RH.
|
| J Biol Chem 283(18):11924-34. Epub 2008 Feb 26. 2008
|
| 188 | APOE, COMT, DAO, DRD1, DRD2, DRD4, DTNBP1, GABRB2, GRIN2B, HP, IL1B, MTHFR, PLXNA2, SCZD23, SLC6A4, TP53, TPH1
|
| Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.
|
| Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L.
|
| Nat Genet 40(7):827-34. 2008
|
| 189 | APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
|
| Inherited susceptibility to common cancers.
|
| Foulkes WD.
|
| N Engl J Med 359(20):2143-53. No abstract available.
2008
|
| 190 | CD44, TP53
|
| Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression.
|
| Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA.
|
| Cell 134(1):62-73.
2008
|
| 191 | LFS1, TP53
|
| Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families.
|
| Bougeard G, Sesboüé R, Baert-Desurmont S, Vasseur S, Martin C, Tinat J, Brugičres L, Chompret A, de Paillerets BB, Stoppa-Lyonnet D, Bonaďti-Pellié C, Frébourg T; French LFS working group.
|
| J Med Genet 45(8):535-8. Epub 2008 May 29.
2008
|
| 192 | BACH1, TP53
|
| Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.
|
| Dohi Y, Ikura T, Hoshikawa Y, Katoh Y, Ota K, Nakanome A, Muto A, Omura S, Ohta T, Ito A, Yoshida M, Noda T, Igarashi K.
|
| Nat Struct Mol Biol 15(12):1246-54. Epub 2008 Nov 16.
2008
|
| 193 | RCHY1, TP53, UBE2D2
|
| Molecular basis of Pirh2-mediated p53 ubiquitylation.
|
| Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH.
|
| Nat Struct Mol Biol 15(12):1334-42. Epub 2008 Nov 30.
2008
|
| 194 | TP53
|
| Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia.
|
| Fabris S, Mosca L, Todoerti K, Cutrona G, Lionetti M, Intini D, Matis S, Colombo M, Agnelli L, Gentile M, Spriano M, Callea V, Festini G, Molica S, Lambertenghi Deliliers G, Morabito F, Ferrarini M, Neri A.
|
| Genes Chromosomes Cancer 47(9):781-93.
2008
|
| 195 | TLR3, TP53
|
| p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines.
|
| Taura M, Eguma A, Suico MA, Shuto T, Koga T, Komatsu K, Komune T, Sato T, Saya H, Li JD, Kai H.
|
| Mol Cell Biol 28(21):6557-67. Epub 2008 Sep 8.PMID: 18779317 2008
|
| 196 | GLI2, TP53, TP63, TP73
|
| Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53.
|
| Katoh Y, Katoh M.
|
| Int J Oncol 33(4):881-6.
2008
|
| 197 | PTBP2, TP53
|
| Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms.
|
| Grover R, Ray PS, Das S.
|
| Cell Cycle 7(14):2189-98. Epub 2008 May 11.
2008
|
| 198 | BCL2, MKI67, TP53
|
| Expression of p53, bcl-2 and Ki-67 in cervical intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
|
| Looi ML, Dali AZ, Ali SA, Ngah WZ, Yusof YA.
|
| Anal Quant Cytol Histol 30(2):63-70.
2008
|
| 199 | CLTC, TP53
|
| Regulation of clathrin-mediated endocytosis by p53.
|
| Endo Y, Sugiyama A, Li SA, Ohmori K, Ohata H, Yoshida Y, Shibuya M, Takei K, Enari M, Taya Y.
|
| Genes Cells 13(4):375-86. doi: 10.1111/j.1365-2443.2008.01172.x.
2008
|
| 200 | YY1, PHB, E2F1, TP53, CASP7
|
| Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.
|
| Joshi B, Rastogi S, Morris M, Carastro LM, DeCook C, Seto E, Chellappan SP.
|
| Biochem J 401(1):155-66. 2007
|
| 201 | RAD23B,TP53
|
| hHR23B is required for genotoxic-specific activation of p53 and apoptosis.
|
| Kaur M, Pop M, Shi D, Brignone C, Grossman SR.
|
| Oncogene 26(8):1231-7. Epub 2006 Aug 21. 2007
|
| 202 | NOTCH1,TP53
|
| Regulation of Notch1 gene expression by p53 in epithelial cells.
|
| Yugawa T, Handa K, Narisawa-Saito M, Ohno S, Fujita M, Kiyono T.
|
| Mol Cell Biol 27(10):3732-42. Epub 2007 Mar 12. 2007
|
| 203 | TP53,ZMIZ1
|
| The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor.
|
| Lee J, Beliakoff J, Sun Z.
|
| Nucleic Acids Res 35(13):4523-34. Epub 2007 Jun 21. 2007
|
| 204 | DVL1L1, TP53
|
| Activation of p53 by Dishevelled independent of Wnt or planar polarity pathways.
|
| Ding VW, Lin LP, Chiang AL, McCormick F.
|
| J Mol Med [Epub ahead of print] 2007
|
| 205 | MAML1, TP53
|
| The notch regulator MAML1 interacts with p53 and functions as a coactivator.
|
| Zhao Y, Katzman RB, Delmolino LM, Bhat I, Zhang Y, Gurumurthy CB, Germaniuk-Kurowska A, Reddi HV, Solomon A, Zeng MS, Kung A, Ma H, Gao Q, Dimri G, Stanculescu A, Miele L, Wu L, Griffin JD, Wazer DE, Band H, Band V.
|
| J Biol Chem 282(16):11969-81. Epub 2007 Feb 22. 2007
|
| 206 | TP53
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| p53 regulates maternal reproduction through LIF.
|
| Hu W, Feng Z, Teresky AK, Levine AJ.
|
| Nature 450(7170):721-4. 2007
|
| 207 | SEMA3F, TP53
|
| Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression.
|
| Futamura M, Kamino H, Miyamoto Y, Kitamura N, Nakamura Y, Ohnishi S, Masuda Y, Arakawa H.
|
| Cancer Res 67(4):1451-60.
2007
|
| 208 | TP53, WDR53
|
| Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer.
|
| Garcia-Closas M, Kristensen V, Langerřd A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Břrresen-Dale AL, Chanock S.
|
| Int J Cancer 121(11):2532-8.
2007
|
| 209 | SIVA1, TP53
|
| Siva is an apoptosis-selective p53 target gene important for neuronal cell death.
|
| Jacobs SB, Basak S, Murray JI, Pathak N, Attardi LD.
|
| Cell Death Differ 14(7):1374-85. Epub 2007 Apr 20.
2007
|
| 210 | STK11, TP53, TUSC3
|
| Deletions of N33, STK11 and TP53 are involved in the development of lymph node metastasis in larynx and pharynx carcinomas.
|
| Guervós MA, Marcos CA, Hermsen M, Nuńo AS, Suárez C, Llorente JL.
|
| Cell Oncol 29(4):327-34.
2007
|
| 211 | TP53, ZNF415
|
| A novel human gene ZNF415 with five isoforms inhibits AP-1- and p53-mediated transcriptional activity.
|
| Cheng Y, Wang Y, Li Y, Deng Y, Hu J, Mo X, Li N, Li Y, Luo N, Yuan W, Xiao J, Zhu C, Wu X, Liu M.
|
| Biochem Biophys Res Commun 351(1):33-9. Epub 2006 Oct 9.
2006
|
| 212 | MDM2, TP53
|
| The central region of HDM2 provides a second binding site for p53.
|
| Yu GW, Rudiger S, Veprintsev D, Freund S, Fernandez-Fernandez MR, Fersht AR.
|
| Proc Natl Acad Sci U S A 103(5):1227-32. Epub 2006 Jan 23. 2006
|
| 213 | ATM, TP53, MYC
|
| ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
|
| Pusapati RV, Rounbehler RJ, Hong S, Powers JT, Yan M, Kiguchi K, McArthur MJ, Wong PK, Johnson DG.
|
| Proc Natl Acad Sci U S A 103(5):1446-51. Epub 2006 Jan 23. 2006
|
| 214 | TP53, MDM2
|
| Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy.
|
| Tovar C, Rosinski J, Filipovic Z, Higgins B, Kolinsky K, Hilton H, Zhao X, Vu BT, Qing W, Packman K, Myklebost O, Heimbrook DC, Vassilev LT.
|
| Proc Natl Acad Sci U S A 103(6):1888-93. Epub 2006 Jan 27. 2006
|
| 215 | ATM, TP53, MTCL
|
| Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma.
|
| Greiner TC, Dasgupta C, Ho VV, Weisenburger DD, Smith LM, Lynch JC, Vose JM, Fu K, Armitage JO, Braziel RM, Campo E, Delabie J, Gascoyne RD, Jaffe ES, Muller-Hermelink HK, Ott G, Rosenwald A, Staudt LM, Im MY, Karaman MW, Pike BL, Chan WC, Hacia JG.
|
| Proc Natl Acad Sci U S A 103(7):2352-7. Epub 2006 Feb 3. 2006
|
| 216 | MDM2, TP53
|
| Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome.
|
| Bougeard G, Baert-Desurmont S, Tournier I, Vasseur S, Martin C, Brugieres L, Chompret A, Bressac-de Paillerets B, Stoppa-Lyonnet D, Bonaiti-Pellie C, Frebourg T.
|
| J Med Genet 43(6):531-3. Epub 2005 Oct 28. 2006
|
| 217 | MDM4, RB1, TP53
|
| Inactivation of the p53 pathway in retinoblastoma.
|
| Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA.
|
| Nature 444(7115):61-6. 2006
|
| 218 | TFAP2A, TFAP2C, TP53
|
| AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells.
|
| Li H, Watts GS, Oshiro MM, Futscher BW, Domann FE.
|
| Oncogene 25(39):5405-15. Epub 2006 Apr 24. 2006
|
| 219 | TP53, SMYD2
|
| Repression of p53 activity by Smyd2-mediated methylation.
|
| Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL.
|
| Nature 444(7119):629-32. Epub 2006 Nov 15. 2006
|
| 220 | PLK1, TP53
|
| Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation.
|
| Chen J, Dai G, Wang YQ, Wang S, Pan FY, Xue B, Zhao DH, Li CJ.
|
| FEBS Lett 580(15):3624-30. Epub 2006 May 30. 2006
|
| 221 | KAT5, TP53
|
| Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis.
|
| Tang Y, Luo J, Zhang W, Gu W.
|
| Mol Cell 24(6):827-39. 2006
|
| 222 | TP53, S100A2
|
| S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.
|
| Lapi E, Iovino A, Fontemaggi G, Soliera AR, Iacovelli S, Sacchi A, Rechavi G, Givol D, Blandino G, Strano S.
|
| Oncogene 25(26):3628-37. Epub 2006 Jan 30. 2006
|
| 223 | FXR2, TP53
|
| Cloning and characterization of the novel chimeric gene p53/FXR2 in the acute megakaryoblastic leukemia cell line CMK11-5.
|
| Kanezaki R, Toki T, Xu G, Narayanan R, Ito E.
|
| Tohoku J Exp Med 209(3):169-80.PMID: 16778363 2006
|
| 224 | PTCH1, SMO, SUFU, TP53
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| Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
|
| Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
|
| Br J Dermatol 152(1):43-51. 2005
|
| 225 | TP53
|
| A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint.
|
| Rohaly G, Chemnitz J, Dehde S, Nunez AM, Heukeshoven J, Deppert W, Dornreiter I.
|
| Cell 122(1):21-32. 2005
|
| 226 | TP53
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| The antioxidant function of the p53 tumor suppressor.
|
| Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM.
|
| Nat Med 11(12):1306-1313. Epub 2005 Nov 13. 2005
|
| 227 | ATF3, TP53
|
| Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination.
|
| Yan C, Lu D, Hai T, Boyd DD.
|
| EMBO J 24(13):2425-35. Epub 2005 Jun 2. 2005
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| 228 | TP53
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| Deletion mapping of chromosome 17 in benign and malignant adrenocortical tumors associated with the Arg337His mutation of the p53 tumor suppressor protein.
|
| Pinto EM, Billerbeck AE, Fragoso MC, Mendonca BB, Latronico AC.
|
| J Clin Endocrinol Metab 90(5):2976-81. Epub 2005 Mar 1. 2005
|
| 229 | TP53, MDM2, MTBP
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| Regulation of p53 and MDM2 activity by MTBP.
|
| Brady M, Vlatkovic N, Boyd MT.
|
| Mol Cell Biol 25(2):545-53. 2005
|
| 230 | CDKN1A, MRPL41, TP53
|
| Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.
|
| Yoo YA, Kim MJ, Park JK, Chung YM, Lee JH, Chi SG, Kim JS, Yoo YD.
|
| Mol Cell Biol 25(15):6603-16. 2005
|
| 231 | TP73, TP53, TERT
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| C-terminal p73 isoforms repress transcriptional activity of the human telomerase reverse transcriptase (hTERT) promoter.
|
| Racek T, Mise N, Li Z, Stoll A, Putzer BM.
|
| J Biol Chem 280(49):40402-5. Epub 2005 Oct 17. 2005
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| 232 | TP53, TP73, TP53INP1
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| TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity.
|
| Tomasini R, Seux M, Nowak J, Bontemps C, Carrier A, Dagorn JC, Pebusque MJ, Iovanna JL, Dusetti NJ.
|
| Oncogene 24(55):8093-104. 2005
|
| 233 | NCL, RPL26, TP53
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| Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin.
|
| Takagi M, Absalon MJ, McLure KG, Kastan MB.
|
| Cell 123(1):49-63. Erratum in: Cell. 2005 Nov 4;123(3):536-7.
2005
|
| 234 | TP53, INHA
|
| Inhibin alpha-subunit (INHA) gene and locus changes in paediatric adrenocortical tumours from TP53 R337H mutation heterozygote carriers.
|
| Longui CA, Lemos-Marini SH, Figueiredo B, Mendonca BB, Castro M, Liberatore R Jr, Watanabe C, Lancellotti CL, Rocha MN, Melo MB, Monte O, Calliari LE, Guerra-Junior G, Baptista MT, Sbragia-Neto L, Latronico AC, Moreira A, Tardelli AM, Nigri A, Taymans SE, Stratakis CA.
|
| J Med Genet 41(5):354-9. 2004
|
| 235 | RFWD2, MDM2, TP53, RCHY1
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| The ubiquitin ligase COP1 is a critical negative regulator of p53.
|
| Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, O'Rourke K, Koeppen H, Dixit VM.
|
| Nature 429(6987):86-92. Epub 2004 Apr 21. 2004
|
| 236 | APTX, XRCC1, TP53, PARP1
|
| Aprataxin, a novel protein that protects against genotoxic stress.
|
| Gueven N, Becherel OJ, Kijas AW, Chen P, Howe O, Rudolph JH, Gatti R, Date H, Onodera O, Taucher-Scholz G, Lavin MF.
|
| Hum Mol Genet 13(10):1081-93. Epub 2004 Mar 25. 2004
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| 237 | MDM2, TP53, NEDD8
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| Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity.
|
| Xirodimas DP, Saville MK, Bourdon JC, Hay RT, Lane DP.
|
| Cell 118(1):83-97. 2004
|
| 238 | ZNF331, MDM2, TP53
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| Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.
|
| Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M, Pramanik A, Selivanova G.
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| Nat Med 10(12):1321-8. Epub 2004 Dec. 2004
|
| 239 | CREBBP, NCOA1, ETS2, TP53, IRF3, EP300
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| A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.
|
| Matsuda S, Harries JC, Viskaduraki M, Troke PJ, Kindle KB, Ryan C, Heery DM.
|
| J Biol Chem 279(14):14055-64. Epub 2004 Jan 13. 2004
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| 240 | ING2, TP53, ING1, SAP30
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| Loss of heterozygosity on chromosome 4q32-35 in sporadic basal cell carcinomas: evidence for the involvement of p33ING2/ING1L and SAP30 genes.
|
| Sironi E, Cerri A, Tomasini D, Sirchia SM, Porta G, Rossella F, Grati FR, Simoni G.
|
| J Cutan Pathol 31(4):318-22. 2004
|
| 241 | CHUK, TP53, ETS1
|
| Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively.
|
| Gu L, Zhu N, Findley HW, Woods WG, Zhou M.
|
| J Biol Chem 279(50):52141-9. Epub 2004 Oct 5. 2004
|
| 242 | STAG1, TP53
|
| Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
|
| Anazawa Y, Arakawa H, Nakagawa H, Nakamura Y.
|
| Oncogene 23(46):7621-7. 2004
|
| 243 | NDRG1, TP53
|
| NDRG1 is necessary for p53-dependent apoptosis.
|
| Stein S, Thomas EK, Herzog B, Westfall MD, Rocheleau JV, Jackson RS 2nd, Wang M, Liang P.
|
| J Biol Chem 279(47):48930-40. Epub 2004 Sep 17. 2004
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| 244 | TP53, TSG3B
|
| Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer.
|
| Marsit CJ, Hasegawa M, Hirao T, Kim DH, Aldape K, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT.
|
| Cancer Res 64(23):8702-7. 2004
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| 245 | PAXIP1, TP53, ATM
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| Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation.
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| Jowsey PA, Doherty AJ, Rouse J.
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| J Biol Chem 279(53):55562-9. Epub 2004 Sep 27. 2004
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| 246 | APC, GBM, HIF1A, PI3K, RB, TP53
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| Cancer genes and the pathways they control.
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| Vogelstein B, Kinzler KW.
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| Nat Med 10(8):789-99. Review. 2004
|
| 247 | TP53, RCHY1
|
| Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.
|
| Duan W, Gao L, Druhan LJ, Zhu WG, Morrison C, Otterson GA, Villalona-Calero MA.
|
| J Natl Cancer Inst 96(22):1718-21. 2004
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| 248 | BRCA1, TP53
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| BRCA1: a scaffold for p53 response?
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| Hohenstein P, Giles RH.
|
| Trends Genet 19(9):489-94. No abstract available. 2003
|
| 249 | ATM, CHEK2, TP53
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| Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.
|
| Keramaris E, Hirao A, Slack RS, Mak TW, Park DS.
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| J Biol Chem 278(39):37782-9. Epub 2003 Jul 11. 2003
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| 250 | USP7, EBNA1BP2 , TP53
|
| Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP.
|
| Holowaty MN, Sheng Y, Nguyen T, Arrowsmith C, Frappier L.
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| J Biol Chem 278(48):47753-61. Epub 2003 Sep 23. 2003
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| 251 | TP53, RRM1, RRM2, RRM2B
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| Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.
|
| Xue L, Zhou B, Liu X, Qiu W, Jin Z, Yen Y.
|
| Cancer Res 63(5):980-6. 2003
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| 252 | DUSP5, TP53
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| Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
|
| Ueda K, Arakawa H, Nakamura Y.
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| Oncogene 22(36):5586-91.
2003
|
| 253 | TP53
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| C-terminus of p53 is required for G(2) arrest.
|
| Nakamura S, Gomyo Y, Roth JA, Mukhopadhyay T.
|
| Oncogene 21(13):2102-7. 2002
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| 254 | DDB2, TP53
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| p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.
|
| Tan T, Chu G.
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| Mol Cell Biol 22(10):3247-54. 2002
|
| 255 | APC, KRAS, TP53, FAP
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| Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.
|
| Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J, Garner RC, Steele RJ, Wolf CR.
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| Proc Natl Acad Sci U S A 99(14):9433-8. 2002
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| 256 | CDKN2A, DLC1, EXT1, MLH1, PTEN, RB1, TP53, TP73
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| Molecular pathogenesis of human hepatocellular carcinoma.
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| Thorgeirsson SS, Grisham JW.
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| Nat Genet 31(4):339-46. 2002
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| 257 | PIN1, TP53
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| The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.
|
| Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wulf G, Gu L, Tang X, Lu KP, Xiao ZX.
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| Nature 419(6909):849-53. 2002
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| 258 | PIN1, TP53
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| The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults.
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| Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G.
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| Nature 419(6909):853-7. 2002
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| 259 | CHEK2, PLK3, TP53
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| Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.
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| Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ.
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| Oncogene 21(43):6633-40. 2002
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| 260 | TP53, TP53BPL2
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| Topors, a p53 and topoisomerase I binding protein, interacts with the adeno-associated virus (AAV-2) Rep78/68 proteins and enhances AAV-2 gene expression.
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| Weger S, Hammer E, Heilbronn R.
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| J Gen Virol 83(Pt 3):511-6. 2002
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| 261 | TP53, TYR
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| Tyrosinase gene expression is regulated by p53.
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| Khlgatian MK, Hadshiew IM, Asawanonda P, Yaar M, Eller MS, Fujita M, Norris DA, Gilchrest BA.
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| J Invest Dermatol 118(1):126-32. 2002
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| 262 | HIPK2, TP53, TP73
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| Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.
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| Kim EJ, Park JS, Um SJ.
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| J Biol Chem 277(35):32020-8. Epub 2002 Mar 29. 2002
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| 263 | TP53
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| A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
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| Zhang Y, Xiong Y.
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| Science 292(5523):1910-5. 2001
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| 264 | TP53, CHEK2, LFS1, LFS2
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| p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition.
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| Vahteristo P, Tamminen A, Karvinen P, Eerola H, Eklund C, Aaltonen LA, Blomqvist C, Aittomaki K, Nevanlinna H.
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| Cancer Res 61(15):5718-22. 2001
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| 265 | ALOX12, ATP1B2, CD68, CHD3, CHRNB1, EIF4A1, FGF11, FXR2, GUCY2D, KDM6B, NEUROD2, SHBG, TNFSF12, TNFSF13, TP53
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| Physical Map of 17p13 and the Genes Adjacent to p53.
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| Cousin P, Billotte J, Chaubert P, Shaw P.
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| Genomics 63(1):60-68. 2000
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| 266 | TP53
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| Mutation analysis of P73 and TP53 in Merkel cell carcinoma.
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| Van Gele M, Kaghad M, Leonard JH, Van Roy N, Naeyaert JM, Geerts ML, Van Belle S, Cocquyt V, Bridge J, Sciot R, De Wolf-Peeters C, De Paepe A, Caput D, Speleman F.
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| Br J Cancer 82(4):823-6. 2000
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| 267 | CREBBP, HD, HTT, TP53
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| The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
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| Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM.
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| Proc Natl Acad Sci U S A 97(12):6763-8. 2000
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| 268 | EP300, MDM2, TP53
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| MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins.
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| Kobet E, Zeng X, Zhu Y, Keller D, Lu H.
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| Proc Natl Acad Sci U S A 97(23):12547-52. 2000
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| 269 | TP53
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| Structural alteration of p53 protein correlated to survival in patients with pancreatic adenocarcinoma.
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| Li Y, et al.
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| Pancreas 18(1):104-10. 1999
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| 270 | ALB, CAD, CCNA2, CDC25A, CDK1, CEBPA, COL1A1, COL1A2, COL3A1, COL6A3, DHFR, DMTF1, GADD45A, JUN, LDHA, MXI1, MYC, ODC1, RCC1, SERPINE1, TERT, TK1, TK2, TP53
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| c-Myc target genes involved in cell growth, apoptosis, and metabolism.
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| Dang CV.
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| Mol Cell Biol 19(1):1-11. Review. No abstract available 1999
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| 271 | MDM2, TP53
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| Functions of the MDM2 oncoprotein.
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| Freedman DA, et al.
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| Cell Mol Life Sci 55(1):96-107. 1999
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| 272 | KRAS, TP53
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| Differences in patterns of TP53 and KRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability.
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| Swisher EM, et al.
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| Cancer 85(1):119-26. 1999
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| 273 | TP53, TSG3B, TSG9A
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| p53 mutation and allelic loss of chromosome 3p, 9p of preneoplastic lesions in patients with nonsmall cell lung carcinoma.
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| Kohno H, et al.
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| Cancer 85(2):341-7. 1999
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| 274 | TP53
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| Mutually compensatory mutations during evolution of the tetramerization domain of tumor suppressor p53 lead to impaired hetero-oligomerization.
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| Mateu MG, et al.
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| Proc Natl Acad Sci U S A 96(7):3595-9. 1999
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| 275 | TP53
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| Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oesophageal cancer.
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| Dunn J, et al.
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| Oncogene 18(4):987-93. 1999
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| 276 | TP53, TSG2B, DLEC1
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| Detection of loss of heterozygosityat microsatellite loci in esophageal squamous-cell carcinoma.
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| Ikeguchi M, et al.
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| Oncology 56(2):164-8. 1999
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| 277 | MSH2, TP53
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| Close correlation between a p53 or hMSH2 gene mutation in the tumor and survival of hepatocellular carcinoma patients.
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| Yano M, et al.
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| Int J Oncol 14(3):447-51. 1999
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| 278 | TSG5A, TSG13A, LOH18CR1, TP53
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| Evolution of neoplastic cell lineages in Barrett oesophagus.
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| Barrett MT, et al.
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| Nat Genet 22(1):106-9. 1999
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| 279 | TP53
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| p53 regulates a G2 checkpoint through cyclin B1.
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| Innocente SA, et al.
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| Proc Natl Acad Sci U S A 96(5):2147-52. 1999
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| 280 | E2F1, NDN, TP53
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| Physical and functional interactions of neuronal growth suppressor necdin with p53.
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| Taniura H, Matsumoto K, Yoshikawa K.
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| J Biol Chem 274(23):16242-8 1999
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| 281 | TP53, WRN
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| Physical and functional interaction between p53 and the Werner's syndrome protein.
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| Blander G, Kipnis J, Leal JF, Yu CE, Schellenberg GD, Oren M.
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| J Biol Chem 274(41):29463-9. 1999
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| 282 | TP53
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| Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer.
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| Storey A, et al.
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| Nature 393 : 229-234. 1998
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| 283 | TP53
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| Pooled analysis of p53 mutations in hematological malignancies.
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| Prokocimer M, et al.
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| Hum Mutat 12 : 4-18. 1998
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| 284 | ATM, TP53
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| ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins.
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| Waterman MJF, et al.
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| Nat Genet 19 : 175-178. 1998
|
| 285 | CD82, TP53
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| The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53.
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| Mashimo T, et al.
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| Proc Natl Acad Sci U S A 95 : 11307-11311. 1998
|
| 286 | APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
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| Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
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| Hooper ML.
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| EMBO J 17(23):6783-9. 1998
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| 287 | BRCA2, RAD51, TP53
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| The BRCA2 gene product functionally interacts with p53 and RAD51.
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| Marmorstein LY, et al.
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| Proc Natl Acad Sci U S A 95 : 13869-13874. 1998
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| 288 | TP53, TSG17A
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| Loss of heterozygosity and microsatellite instability in de novo versus ex-adenoma carcinomas of the colorectum.
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| Mueller JD, et al.
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| Am J Pathol 153 : 1977-1984. 1998
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| 289 | TP53, TSG17A
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| New splicing mutation in exon 5-6 of the p53-tumor suppressor gene in a malignant schwannoma.
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| Schneider-Stock R, et al.
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| Hum Mutat 9 : 91-94. 1997
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| 290 | TP53, TSG17A
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| A detailed study of loss of heterozygosity on chromosome 17 in tumours from Li-Fraumeni patients carrying a mutation to the TP53 gene.
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| Varley JM, et al.
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| Oncogene 14 : 865-871. 1997
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| 291 | TP53
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| Cell cycle arrest defect in Li-Fraumeni syndrome : a mechanism of cancer predisposition ?
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| Williams KJ, et al.
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| Oncogene 14 : 277-282. 1997
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| 292 | APC, TP53, FAP
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| Database of mutations in the p53 and APC tumor suppressor genes designedto facilitate molecular epidemiological analyses.
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| de Vries EMG, et al.
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| Hum Mutat 7 : 202-213. 1996
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| 293 | TP53, TSG17A
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| A novel deletion within exon 6 of TP53 in a family with Li-Fraumeni-like syndrome, and LOH in a benign lesion from a mutation carrier.
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| Varley JM, et al.
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| Cancer Genet Cytogenet 90 : 14-16. 1996
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| 294 | TP53, TSG17A
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| A nonsense mutation (Arg-196-Term) in exon 6 of the human TP53 gene identified in small cell lung carcinoma.
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| Hayes VM, et al.
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| Mol Cell Probes 10 : 393-395. 1996
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| 295 | TP53
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| Short report on DNA marker at candidate locus. A polymorphism in intron 2 of the TP53 gene.
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| DiCioccio RA, et al.
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| Clin Genet 50 : 108-109. 1996
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| 296 | TP53, TSG17A
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| Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ.
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| Munn KE, et al.
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| Br J Cancer 74 : 1578-1585. 1996
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| 297 | LFS1, TP53, TSG17A
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| An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53.
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| Varley JM, et al.
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| J Med Genet 32 : 942-945. 1995
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| 298 | TP53
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| Polymorphism of the pentanucleotide repeat dX(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1).
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| Hahn M, et al.
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| Hum Genet 95 : 471-472. 1995
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| 299 | XPD, TP53, XPB
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| p53 modulation of TFIIH-associated nucleotide excision repair activity.
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| Wang XW, et al.
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| Nat Genet 10 : 188-195. 1995
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| 300 | TP53
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| A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.
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| Nicol CJ, et al.
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| Nat Genet 10 : 181-187. 1995
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| 301 | TP53
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| A subset of p53-deficient embryos exhibit exencephaly.
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| Sah VP, et al.
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| Nat Genet 10 : 175-180. 1995
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| 302 | TP53
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| Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.
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| Jeffrey PD, et al.
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| Science 267(5203):1498-502. 1995
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| 303 | TP53
|
| HaeIII polymorphism in intron 1 of the human p53 gene.
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| Ito T, et al.
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| Hum Genet 93 : 222. 1994
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| 304 | LFS1, TP53
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| Splice-site mutation of the p53 gene in a family with hereditary breast-ovarian cancer.
|
| Jolly KW, et al.
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| Oncogene 9 : 97-102. 1994
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| 305 | TP53
|
| Polymorphism at codon 36 of the p53 gene.
|
| Felix CA, et al.
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| Oncogene 9 : 327-328. 1994
|
| 306 | TSG17A, TP53
|
| Detailed analysis of loss of heterozygosity on chromosome band 17p13 in breast carcinoma on the basis of a high-resolution physical map with 29 markers.
|
| Isomura M, et al.
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| Genes Chromosomes Cancer 9 : 173-179. 1994
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| 307 | TP53
|
| Identification of a polymorphism in intron 2 of the p53 gene.
|
| Pleasants LM, et al.
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| Hum Genet 93 : 607-608. 1994
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| 308 | TP53, TSG17A
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| Anaplastic Wilms'tumour, a subtype displaying poor prognosis, harbours p53 gene mutations.
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| Bardeesy N, et al.
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| Nat Genet 7 : 91-97. 1994
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| 309 | LFS1, TP53
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| Single base pair germ-line deletion in the p53 gene in a cancer predisposed family.
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| Hamelin R, et al.
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| Hum Genet 94 : 88-90. 1994
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| 310 | TP53
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| X-rays strike p53 again.
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| Vogelstein B, et al.
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| Nature 370 : 174-175. 1994
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| 311 | TP53, LFS1
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| A germline 2.35 kb deletion of p53 genomic DNA creating a specific loss of the oligomerization domain inherited in a Li-Fraumeni syndrome family.
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| Plummer SJ, et al.
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| Oncogene 9 : 3273-3280. 1994
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| 312 | TP53
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| A De novo p53 germline mutation affecting codon 151 in a six year old child with multiple tumors.
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| Gutirrez MI, et al.
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| Hum Mol Genet 3 : 2247-2248. 1994
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| 313 | TP53
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| Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
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| Cho Y, et al.
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| Science 265(5170):346-55. 1994
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| 314 | TP53, TSG17A
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| Constitutional mutation in exon 8 of the p53 gene in a patient with multiple tumours : molecular and immunohistochemical findings.
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| Eeles RA, et al.
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| Oncogene 8 : 1269-1276. 1993
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| 315 | TSG17A, TP53
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| A new mutation of exon 5 of the P53 gene in breast cancer.
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| Carrere N, et al.
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| Hum Mol Genet 2 : 1075. 1993
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| 316 | TP53, LFS1
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| A functionally inactive p53 Li-Fraumeni syndrome mutant.
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| Hao M, et al.
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| Oncogene 8 : 299-306. 1993
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| 317 | TP53
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| PCR detection of a neutral CGA/CGG dimorphism in exon 6 of the human p53 gene.
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| Bhatia K, et al.
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| Nucleic Acids Res 20 : 928. 1992
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| 318 | TP53
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| A new TaqI polymorphism in the p53 gene.
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| Serra A, et al.
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| Nucleic Acids Res 20 : 928. 1992
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| 319 | TP53
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| TP53 tumor suppressor gene : a model for investigating human mutagenesis.
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| Caron de Fromentel C, et al.
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| Genes Chromosomes Cancer 4 : 1-15. 1992
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| 320 | TP53
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| Prevalence and spectrum of germiline mutations of the p53 gene among patients with sarcoma.
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| Toguchida J, et al.
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| N Engl J Med 326 : 1301-1308. 1992
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| 321 | TP53
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| Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms.
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| Malkin D, et al.
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| N Engl J Med 326 : 1309-1315. 1992
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| 322 | TP53
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| Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism.
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| Jones MH, et al.
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| Genes Chromosomes Cancer 5 : 89-90. 1992
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| 323 | TP53
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| Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas.
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| Buetow KH, et al.
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| Proc Natl Acad Sci U S A 89 : 9622-9626. 1992
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| 324 | TP53
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| Analysis of the p53 tumor-suppressor gene in hepatocellular carcinomas from Britain.
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| Challen C, et al.
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| Hepatology 16 : 1362-1366. 1992
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| 325 | TP53
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| Expression of p53 and 17p allelic loss in colorectal carcinoma.
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| Cunningham J, et al.
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| Cancer Res 52 : 1974-1980. 1992
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| 326 | TP53
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| Mutations of the p53 gene in B-cell lymphoblastic acute leukemia : a report on 60 cases.
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| Fenaux P, et al.
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| Blood 6 : 42-46. 1992
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| 327 | TP53
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| Mutations of the p53 gene in B-cell chronic lymphocytic leukemia : a report on 39 cases with cytogenetic analysis.
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| Fenaux P, et al.
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| Leukemia 6 : 246-250. 1992
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| 328 | TP53
|
| Mutations of the P53 gene in acute myeloid leukaemia.
|
| Fenaux P, et al.
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| Br J Haematol 80 : 178-183. 1992
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| 329 | TP53
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| Frequent association of p53 gene mutation in invasive bladder cancer.
|
| Fujimoto K, et al.
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| Cancer Res 52 : 1393-1398. 1992
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| 330 | TP53, TSG17A
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| p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression.
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| Fults D, et al.
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| Cancer Res 52 : 674-679. 1992
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| 331 | RB1, TP53, MCC, APC, TSG5A, TSG13A, TSG17A
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| Loss of heterozygosity affecting the p53, Rb, and mcc/apc tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis.
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| Greenwald BD, et al.
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| Cancer Res 52 : 741-745. 1992
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| 332 | TP53
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| P53 gene mutations in acute myelogenous leukaemia.
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| Hu G, et al.
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| Br J Haematol 81 : 489-494. 1992
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| 333 | TP53
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| Mutations of p53 gene and their relation to disease progression in B-cell lymphoma.
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| Ichikawa A, et al.
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| Blood 79 : 2701-2707. 1992
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| 334 | MYC, FOS, TP53
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| Co-ordinate expression of c-fos, p53 and cytokeratin genes during the alteration of growth of human hepatoma cells; mRNA levels measured by reverse transcription and polymerase chain reaction.
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| Kaneko Y, et al.
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| Cancer Lett 66 : 155-164. 1992
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| 335 | TP53
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| P53 mutations in myelodysplastic syndromes.
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| Ludwig L, et al.
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| Leukemia 6 : 1302-1304. 1992
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| 336 | TP53, TSG17A
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| High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx.
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| Maestro R, et al.
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| Oncogene 7 : 1159-1166. 1992
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| 337 | TP53, TSG17A
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| p53 gene mutations in human gastric cancer : wild-type p53 but not mutant p53 suppresses growth of human gastric cancer cells.
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| Matozaki T, et al.
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| Cancer Res 52 : 4335-4341. 1992
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| 338 | TP53, TSG17A
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| p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.
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| Mitsudomi T, et al.
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| Oncogene 7 : 171-180. 1992
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| 339 | TP53
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| Structural alterations of the p53 gene in human leukemias.
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| Miwa H, et al.
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| Leuk Res 6 : 1105-1112. 1992
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| 340 | TP53
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| Two distinct mechanisms alter p53 in breast cancer : mutation and nuclear exclusion.
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| Moll UM, et al.
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| Proc Natl Acad Sci U S A 89 : 7262-7266. 1992
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| 341 | TP53
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| Detection of p53 gene mutations in human ovarian and endometrial cancers by polymerase chain reaction-single strand conformation polymorphism analysis.
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| Naito M, et al.
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| Jpn J Cancer Res 83 : 1030-1036. 1992
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| 342 | TP53, TSG17A
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| p53 mutations in human hepatocellular carcinomas from Germany.
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| Kress S, et al.
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| Cancer Res 52 : 3220-3323. 1992
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| 343 | TP53
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| Mutations of the p53 tumour suppressor gene in haematologic neoplasms.
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| Mori N, et al.
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| Br J Haematol 81 : 235-240. 1992
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| 344 | TP53
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| Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma.
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| Oda T, et al.
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| Cancer Res 52 : 3674-3678. 1992
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| 345 | TP53
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| Rare occurence of P53 gene mutations in multiple myeloma.
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| Preudhomme C, et al.
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| Br J Haematol 81 : 440-443. 1992
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| 346 | TP53, RB1
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| Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes.
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| Ruggeri B, et al.
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| Oncogene 7 : 1503-1511. 1992
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| 347 | TP53, TSG17A
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| Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
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| Sakai E, et al.
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| Oncogene 7 : 927-933. 1992
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| 348 | TP53
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| Detection of novel germ-line p53 mutations in diverse-cancer-prone families identified by selecting patients with childhood adrenocortical carcinoma.
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| Sameshima Y, et al.
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| J Natl Cancer Inst 84 : 703-707. 1992
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| 349 | TSG17A, TP53
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| p53 gene mutations in primary lung tumors are conserved in brain metastases.
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| Schlegel U, et al.
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| J Neurooncol 14 : 93-100. 1992
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| 350 | TP53
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| Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.
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| Shaw P, et al.
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| Proc Natl Acad Sci U S A 89 : 4495-4499. 1992
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| 351 | TSG17A, TP53, LFS1
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| Detection of both mutant and wild-type p53 protein in normal skin fibroblasts and demonstration of a shared second hit on p53 in diverse tumors from a cancer-prone family with Li-Fraumeni syndrome.
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| Srivastava S, et al.
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| Oncogene 7 : 987-991. 1992
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| 352 | TP53, TSG17A
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| An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.
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| Sun Y, et al.
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| Proc Natl Acad Sci U S A 89 : 6516-6520. 1992
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| 353 | TP53
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| p53 mutations in non-small cell lung cancer in Japan : association between mutations and smoking.
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| Suzuki H, et al.
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| Cancer Res 52 : 734-736. 1992
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| 354 | TP53, TSG17A
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| p53 gene mutation in esophageal cancer detected by polymerase chain reaction single-strand conformation polymorphism analysis.
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| Tamura G, et al.
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| Jpn J Cancer Res 83 : 559-562. 1992
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| 355 | TP53
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| p53 mutations occur in aggressive breast cancer.
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| Mazars R, et al.
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| Cancer Res 52 : 3918-3923. 1992
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| 356 | TP53
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| Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung.
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| Kishimoto Y, et al.
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| Cancer Res 52 : 4799-4804. 1992
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| 357 | TP53
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| Frequent p53 mutations in head and neck cancer.
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| Somers KD, et al.
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| Cancer Res 52 : 5997-6000. 1992
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| 358 | TP53
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| Absence of p53 gene mutations in primary Nasopharyngeal carcinomas.
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| Spruck CH, et al.
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| Cancer Res 52 : 4787-4790. 1992
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| 359 | TP53
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| Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines.
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| Yaginuma Y, et al.
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| Cancer Res 52 : 4196-4199. 1992
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| 360 | TP53
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| Role of p53 mutations in endocrine tumorigenesis : mutation detection by polymerase chain reaction-single strand conformation polymorphism.
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| Yoshimoto K, et al.
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| Cancer Res 52 : 5061-5064. 1992
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| 361 | TP53
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| PCR detection of a BgIII polymorphism in intron I of the human p53 gene (TP53).
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| Willems PM, et al.
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| Nucleic Acids Res 20 : 1172. 1992
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| 362 | LFS1, TP53
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| Abnormal expression of wild type p53 protein in normal cells of a cancer family patient.
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| Barnes DM, et al.
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| Lancet 340 : 259-263. 1992
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| 363 | TP53
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| Identification of p53 gene mutations in bladder cancers and urine samples.
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| Science 252 : 706-709. 1991
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| 364 | TP53
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| The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
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| Scheffner M, et al.
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| Proc Natl Acad Sci U S A 88 : 5523-5527. 1991
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| 365 | TP53
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| Identification of p53 as a sequence-specific DNA binding protein.
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| Kern SE, et al.
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| Science 252 : 1708-1710. 1991
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| 366 | TP53
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| Biallelic ApaI polymorphism of the human p53 gene (TP53).
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| Prosser J, et al.
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| Nucleic Acids Res 19 : 4799. 1991
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| 367 | TP53
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| The MspI polymorphism in intron 6 of p53 (TP53) detected by digestion of PCR products.
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| McDaniel T, et al.
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| Nucleic Acids Res 19 : 4796. 1991
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| 368 | TP53
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| Monosomy 17p and hemizygosity of the P53 locus in acute lymphoblastic leukemia.
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| Hawkins JM, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2005. 1991
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| 369 | TP53
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| Overexpression of P53 protein and correlation with DNA mutations in melanoma, nasopharyngeal and liver carcinomas.
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| Kennedy S, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2006. 1991
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| 370 | TP53
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| BstNI/NciI polymorphism of the human p53 gene (TP53).
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| Chumakov PM, et al.
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| Nucleic Acids Res 19 : 6969. 1991
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| 371 | TP53
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| An Alu polymorphism intragenic to the TP53 gene.
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| Futreal PA, et al.
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| Nucleic Acids Res 19 : 6977. 1991
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| 372 | TP53
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| Polymorphism at codon 213 within p53 gene.
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| Carbone D, et al.
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| Oncogene 6 : 1691-1692. 1991
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| 373 | TP53
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| A role for sunlight in skin cancer : UV-induced p53 mutations in squamous cell carcinoma.
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| Brash DE, et al.
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| Proc Natl Acad Sci U S A 88 : 10124-10128. 1991
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| 374 | TP53
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| Frequent loss of a p53 allele in carcinomas and their prcursors in ulcerative colitis.
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| Burmer GC, et al.
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| Cancer Commun 23 : 167-172. 1991
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| 375 | TP53
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| p53 is frequently mutated in Burkitt's lymphoma cell lines.
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| Farrell PJ, et al.
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| EMBO J 10 : 2879-2887. 1991
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| 376 | TP53
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| P53 gene mutations in acute myeloid leukemia with 17p monosomy.
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| Fenaux P, et al.
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| Blood 78 : 1652-1657. 1991
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| 377 | TP53
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| p53 mutations in human lymphoid malignancies : association with Burkitt lymphoma and chronic lymphocytic leukemia.
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| Gaidano G, et al.
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| Proc Natl Acad Sci U S A 88 : 5413-5417. 1991
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| 378 | TP53
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| Timing and role of p53 gene mutation in the recurrence of glioma.
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| Hayashi Y, et al.
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| Biochem Biophys Res Commun 180 : 1145-1150. 1991
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| 379 | TP53
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| Mutations in the p53 gene in myelodysplastic syndromes.
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| Jonveaux P, et al.
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| Oncogene 6 : 2243-2247. 1991
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| 380 | TP53
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| Infrequent mutations in the P53 gene in primary human T-cell acute lymphoblastic leukemia.
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| Jonveaux P, et al.
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| Leukemia 5 : 839-840. 1991
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| 381 | TP53, LFS1
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| A germ line mutation in exon 5 of the p53 gene in an extended cancer family.
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| Law JC, et al.
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| Cancer Res 51 : 6385-6387. 1991
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| 382 | TP53, TSG17A
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| Detection of p53 gene mutations in human brain tumors by single-strand conformation polymorphism analysis of polymerase chain reaction products.
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| Mashiyama S, et al.
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| Oncogene 6 : 1313-1318. 1991
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| 383 | TP53, TSG17A
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| p53 mutations in ovarian cancer : a late event?
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| Mazars R, et al.
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| Oncogene 6 : 1685-1690. 1991
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| 384 | TP53, TSG17A
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| Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction.
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| Meltzer SJ, et al.
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| Proc Natl Acad Sci U S A 88 : 4976-4980. 1991
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| 385 | TP53, TSG17A
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| Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma.
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| Metzger AK, et al.
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| Proc Natl Acad Sci U S A 88 : 7825-7829. 1991
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| 386 | TP53
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| Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by single-strand conformation polymorphism analysis.
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| Murakami Y, et al.
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| Cancer Res 51 : 3356-3361. 1991
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| 387 | TP53, TSG17A
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| Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.
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| Cancer Res 51 : 5171-5176. 1991
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| 388 | TP53
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| Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population.
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| Olschwang S, et al.
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| Hum Genet 86 : 369-370. 1991
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| 389 | TP53, TSG17A
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| Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas.
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| Pierceall WE, et al.
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| Mol Carcinog 4 : 445-449. 1991
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| 390 | TP53, TSG17A
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| Mutations in p53 as potential molecular markers for human breast cancer.
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| Runnebaum IB, et al.
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| Proc Natl Acad Sci U S A 88 : 10657-10661. 1991
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| 391 | TP53
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| Mutation of the p53 gene in human acute myelogenous leukemia.
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| Slingerland JM, et al.
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| Blood 77 : 1500-1507. 1991
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| 392 | TP53
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| Adult T-cell leukemia : structures and expression of the p53 gene.
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| Sugito S, et al.
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| Int J Cancer 49 : 880-885. 1991
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| 393 | TP53
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| Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction single-strand conformation polymorphism analysis.
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| Tamura G, et al.
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| Cancer Res 51 : 3056-3058. 1991
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| 394 | TP53
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| Mutation of the p53 gene in a differentiated human thyroid carcinoma cell line, but not in primary thyroid tumours.
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| Wright PA, et al.
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| Oncogene 6 : 1693-1697. 1991
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| 395 | TP53
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| Analysis of the p53 gene in human uterine carcinoma cell lines.
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| Yaginuma Y, et al.
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| Cancer Res 51 : 6506-6509. 1991
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| 396 | TP53
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| p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.
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| Yamada Y, et al.
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| Cancer Res 51 : 5800-5805. 1991
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| 397 | LFS1, TP53
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| p53 germline mutations in Li-Fraumeni syndrome.
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| Santibanez-Koref MF, et al.
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| Lancet 338 : 1490-1491. 1991
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| 398 | TSG17A, TP53
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| Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa.
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| Bressac B, et al.
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| Nature 350 : 429-431. 1991
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| 399 | LFS1, TP53, TSG17A
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| Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
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| Malkin D, et al.
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| Science 250 : 1233-1238. 1990
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| 400 | TP53
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| Increased expression of mutant forms of p53 oncogene in primary lung cancer.
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| Iggo R, et al.
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| Lancet 335 : 675-679. 1990
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| 401 | TP53
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| Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer.
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| Takahashi T, et al.
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| J Clin Invest 86 : 363-369. 1990
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| 402 | NF1, TP53
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| Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.
|
| Menon AG, et al.
|
| Proc Natl Acad Sci U S A 87 : 5435-5439. 1990
|
| 403 | TP53
|
| AccII polymorphism of the p53 gene.
|
| La Calle-Martin O de, et al.
|
| Nucleic Acids Res 18 : 4963. 1990
|
| 404 | TP53
|
| Codon 72 polymorphism of the TP53 gene.
|
| Ara S, et al.
|
| Nucleic Acids Res 18 : 4961. 1990
|
| 405 | TP53
|
| MspI polymorphism of the human p53 gene.
|
| La Calle-Martin O de, et al.
|
| Nucleic Acids Res 18 : 4963. 1990
|
| 406 | LFS1, TP53, TSG17A
|
| Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome.
|
| Srivastava S, et al.
|
| Nature 348 : 747-749. 1990
|
| 407 | tp53
|
| Point mutation of the p53 gene resulting in splicing inhibition in small cell lung carcinoma.
|
| Sameshima Y, et al.
|
| Biochem Biophys Res Commun 173 : 697-703. 1990
|
| 408 | TP53
|
| Biallelic Bgl II DNA polymorphism of the human p53 oncogene.
|
| La Calle O de, et al.
|
| Nucleic Acids Res 18 : 206. 1990
|
| 409 | TP53, TSG17A
|
| Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas.
|
| El-Azouzi M, et al.
|
| Proc Natl Acad Sci U S A 86 : 7186-7190. 1989
|
| 410 | TP53
|
| p53 : a frequent target for genetic abnormalities in lung cancer.
|
| Takahashi T, et al.
|
| Science 246 : 491-494. 1989
|
| 411 | TP53
|
| Mutations in the p53 gene occur in diverse human tumour types.
|
| Nigro JM, et al.
|
| Nature 342 : 705-708. 1989
|
| 412 | TP53
|
| A BamHI-polymorphism is detected by a genomic p53-clone (pBHP53).
|
| Hyheim B, et al.
|
| Nucleic Acids Res 17 : 8898. 1989
|
| 413 | HNPCC3, TP53, TSG17A, TP53, D17S65, D17S66, D17S68, D17S70, D17S126, D17S127
|
| Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas.
|
| Baker SJ, et al.
|
| Science 244 : 217-221. 1989
|
| 414 | TP53
|
| BanII and ScaI RFLPs at the human p53 gene locus.
|
| Masharani U, et al.
|
| Nucleic Acids Res 16 : 7757. 1988
|
| 415 | TP53
|
| Rearrangement of the p53 gene in human osteogenic sarcomas.
|
| Masuda H, et al.
|
| Proc Natl Acad Sci U S A 84 : 7716-7719. 1987
|
| 416 | TP53
|
| Localization of gene for human p53 tumour antigen to band 17p13.
|
| Isobe M, et al.
|
| Nature 320 : 84-85. 1986
|
| 417 | TP53
|
| Characterization of the human p53 gene.
|
| Lamb P, et al.
|
| Mol Cell Biol 6 : 1379-1385. 1986
|
| 418 | TP53
|
| The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13).
|
| McBride OW, et al.
|
| Proc Natl Acad Sci U S A 83 : 130-134. 1986
|
| 419 | TP53
|
| Human p53 gene localized to short arm of chromosome 17.
|
| Miller C, et al.
|
| Nature 319 : 783-784. 1986
|
| 420 | TP53
|
| Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia.
|
| Le Beau MM, et al.
|
| Nature 316 : 826-828. 1985
|
| 421 | TP53
|
| Human p53 cellular tumor antigen is on chromosome 17p13.
|
| McBride OW, et al.
|
| (HGM8) Cytogenet Cell Genet 40 : 694-695. 1985
|
| 422 | TP53
|
| Human p53 is on the short arm of chromosome 17.
|
| Benchimol S, et al.
|
| (HGM8) Cytogenet Cell Genet 40 : 580-581. 1985
|