| 1 | TOP1
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| Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter.
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| Cho JE, Kim N, Jinks-Robertson S.
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| Nucleic Acids Res 43(19):9306-13. doi: 10.1093/nar/gkv824. Epub 2015 Aug 13.
2015
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| 2 | TOP1
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| DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.
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| Wright CM, van der Merwe M, DeBrot AH, Bjornsti MA.
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| J Biol Chem 290(19):12068-78. doi: 10.1074/jbc.M114.635078. Epub 2015 Mar 20.
2015
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| 3 | PIAS1, RECQL5, SRSF1, TOP1
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| RECQ5-dependent SUMOylation of DNA topoisomerase I prevents transcription-associated genome instability.
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| Li M, Pokharel S, Wang JT, Xu X, Liu Y.
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| Nat Commun 6:6720. doi: 10.1038/ncomms7720.
2015
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| 4 | TOP1
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| Topoisomerase 1 inhibition reversibly impairs synaptic function.
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| Mabb AM, Kullmann PH, Twomey MA, Miriyala J, Philpot BD, Zylka MJ.
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| Proc Natl Acad Sci U S A 111(48):17290-5. doi: 10.1073/pnas.1413204111. Epub 2014 Nov 17.
2014
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| 5 | TDP1, TDP2, TOP1, TOP1MT
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| Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).
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| Pommier Y, Huang SY, Gao R, Das BB, Murai J, Marchand C.
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| DNA Repair (Amst) 19:114-29. doi: 10.1016/j.dnarep.2014.03.020. Epub 2014 May 22. Review.
2014
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| 6 | RET, TOP1, TOP2A
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| DNA topoisomerases participate in fragility of the oncogene RET.
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| Dillon LW, Pierce LC, Lehman CE, Nikiforov YE, Wang YH.
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| PLoS One 8(9):e75741. doi: 10.1371/journal.pone.0075741. eCollection 2013.
2013
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| 7 | TOP1
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| Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA.
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| Williams JS, Smith DJ, Marjavaara L, Lujan SA, Chabes A, Kunkel TA.
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| Mol Cell 49(5):1010-5. doi: 10.1016/j.molcel.2012.12.021. Epub 2013 Jan 31.
2013
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| 8 | CCR7, TOP1
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| The autoantigen DNA topoisomerase I interacts with chemokine receptor 7 and exerts cytokine-like effects on dermal fibroblasts.
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| Arcand J, Robitaille G, Koenig M, Senécal JL, Raymond Y.
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| Arthritis Rheum 64(3):826-34. doi: 10.1002/art.33377.
2012
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| 9 | TDP1, TOP1
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| Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells.
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| Hubert L Jr, Lin Y, Dion V, Wilson JH.
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| Mol Cell Biol 31(15):3105-12. doi: 10.1128/MCB.05158-11. Epub 2011 May 31.
2011
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| 10 | TOP1
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| Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.
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| Kobayashi M, Sabouri Z, Sabouri S, Kitawaki Y, Pommier Y, Abe T, Kiyonari H, Honjo T.
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| Proc Natl Acad Sci U S A 108(48):19305-10. doi: 10.1073/pnas.1114522108. Epub 2011 Nov 11.
2011
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| 11 | TOP1
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| Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
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| Ryan D, Rafferty M, Hegarty S, O'Leary P, Faller W, Gremel G, Bergqvist M, Agnarsdottir M, Strömberg S, Kampf C, Pontén F, Millikan RC, Dervan PA, Gallagher WM.
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| Pigment Cell Melanoma Res 23(4):542-53. doi: 10.1111/j.1755-148X.2010.00720.x. Epub 2010 Apr 30.
2010
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| 12 | TOP1
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| A genetic screen identifies topoisomerase 1 as a regulator of senescence.
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| Humbert N, Martien S, Augert A, Da Costa M, Mauen S, Abbadie C, de Launoit Y, Gil J, Bernard D.
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| Cancer Res 69(10):4101-6. doi: 10.1158/0008-5472.CAN-08-2864. Epub 2009 May 12.
2009
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| 13 | TOP1
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| Fragment responsible for translocation in the N-terminal domain of human topoisomerase I.
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| Girstun A, Kowalska-Loth B, Czubaty A, Klocek M, Staroñ K.
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| Biochem Biophys Res Commun 366(1):250-7. Epub 2007 Dec 3.
2008
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| 14 | TOP1
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| Topoisomerase I requirement for death receptor-induced apoptotic nuclear fission.
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| Sordet O, Goldman A, Redon C, Solier S, Rao VA, Pommier Y.
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| J Biol Chem 283(34):23200-8. Epub 2008 Jun 13.
2008
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| 15 | TOP1
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| Poly(ADP-ribose) binds to the splicing factor ASF/SF2 and regulates its phosphorylation by DNA topoisomerase I.
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| Malanga M, Czubaty A, Girstun A, Staron K, Althaus FR.
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| J Biol Chem 283(29):19991-8. Epub 2008 May 21.
2008
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| 16 | TOP1
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| Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition.
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| Laco GS, Pommier Y.
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| Biochem J 411(3):523-30.
2008
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| 17 | TOP1
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| Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I.
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| Hackbarth JS, Galvez-Peralta M, Dai NT, Loegering DA, Peterson KL, Meng XW, Karnitz LM, Kaufmann SH.
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| J Biol Chem 283(24):16711-22. Epub 2008 Apr 11.
2008
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| 18 | LMNB2, TOP1, TOP2A
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| Functional interactions of DNA topoisomerases with a human replication origin.
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| Abdurashidova G, Radulescu S, Sandoval O, Zahariev S, Danailov MB, Demidovich A, Santamaria L, Biamonti G, Riva S, Falaschi A.
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| EMBO J 26(4):998-1009. Epub 2007 Feb 8. 2007
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| 19 | ATM, TOP1
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| ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain.
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| Gorodetsky E, Calkins S, Ahn J, Brooks PJ.
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| DNA Repair (Amst) 6(11):1698-707. Epub 2007 Aug 13.PMID: 17706468 2007
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| 20 | TOP1
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| Human topoisomerase I forms double cleavage complexes on natural DNA.
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| Søe K, Hartung S, Grosse F.
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| Biochem Biophys Res Commun 349(1):178-85. Epub 2006 Aug 14.
2006
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| 21 | TOP1
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| Assembly of a polymeric chain of SUMO1 on human topoisomerase I in vitro.
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| Yang M, Hsu CT, Ting CY, Liu LF, Hwang J.
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| J Biol Chem 281(12):8264-74. Epub 2006 Jan 20.
2006
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| 22 | TOP1
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| The N-terminal domain anchors human topoisomerase I at fibrillar centers of nucleoli and nucleolar organizer regions of mitotic chromosomes.
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| Christensen MO, Barthelmes HU, Boege F, Mielke C.
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| J Biol Chem 277(39):35932-8. Epub 2002 Jul 15. 2002
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| 23 | NUP98, TOP1
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| The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion.
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| Ahuja HG, Felix CA, Aplan PD.
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| Blood 94(9):3258-61 1999
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| 24 | TOP1
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| Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin.
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| Desai SD, Liu LF, Vazquez-Abad D, D'Arpa P.
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| J Biol Chem 272(39):24159-64. 1997
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| 25 | TOP1
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| Localization of the type I DNA topoisomerase gene in man and mouse.
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| Rettenberger G, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2032. 1991
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| 26 | TOP1
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| A three allele TaqI polymorphism at TOP1 gene.
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| Sunde L, et al.
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| Nucleic Acids Res 18 : 5919. 1990
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| 27 | TOP1, TOP1P1, TOP1P2
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| Localization of the active type I DNA topoisomerase gene on human chromosome 20q11.2-13.1, and two pseudogenes on chromosomes 1q23-24 and 22q11.2-13.1.
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| Kunze N, et al.
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| Hum Genet 84 : 6-10. 1989
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| 28 | TOP1
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| Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2.
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| Juan CC, Hwang JL, Liu AA, Whang-Peng J, Knutsen T, Huebner K, Croce CM, Zhang H, Wang JC, Liu LF.
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| Proc Natl Acad Sci U S A 85 : 8910-8913. 1988
|