1 | BTG1, BTG2, BTG3, BTG4, CNOT7, CNOT8, TOB1, TOB2
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| The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.
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| Doidge R, Mittal S, Aslam A, Winkler GS.
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| PLoS One. ;7(12):e51331. doi: 10.1371/journal.pone.0051331. Epub 2012 Dec 7 2012
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2 | CNOT8, CPEB3, TOB1
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| Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.
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| Hosoda N, Funakoshi Y, Hirasawa M, Yamagishi R, Asano Y, Miyagawa R, Ogami K, Tsujimoto M, Hoshino S.
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| EMBO J 30(7):1311-23. Epub 2011 Feb 18.
2011
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3 | CORO7, TOB1
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| Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.
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| Watanabe M, Suzuki T, Kim M, Abe Y, Yoshida Y, Sugano S, Yamamoto T.
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| FEBS Lett 585(1):65-70. Epub 2010 Dec 3.
2011
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4 | BTG1, BTG2, BTG3, BTG4, CNOT7, CNOT8, TOB1, TOB2
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| The mammalian anti-proliferative BTG/Tob protein family.
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| Winkler GS.
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| J Cell Physiol 222(1):66-72. Review.PMID: 19746446 2010
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5 | IFRD1,TOB1
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| Regulation and localization of TOB and IFR1 in differentiating red cells.
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| Steiner SK, Baumann R, Dragon S.
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| Biochem Biophys Res Commun 359(4):1010-6. Epub 2007 Jun 11. 2007
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6 | PABPC1, TOB1
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| Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.
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| Ezzeddine N, Chang TC, Zhu W, Yamashita A, Chen CY, Zhong Z, Yamashita Y, Zheng D, Shyu AB.
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| Mol Cell Biol 27(22):7791-801. Epub 2007 Sep 4. 2007
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7 | TOB1, TOB2
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| Tob genes in development and homeostasis.
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| Jia S, Meng A.
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| Dev Dyn 236(4):913-21. Review.PMID: 17304515 2007
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8 | TOB1, TOB2
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| Tob proteins suppress steroid hormone receptor-mediated transcriptional activation.
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| Kawate H, Wu Y, Ohnaka K, Nawata H, Takayanagi R.
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| Mol Cell Endocrinol 230(1-2):77-86.PMID: 15664454 2005
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9 | TOB1, TOB2
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| Nuclear localization of Tob is important for regulation of its antiproliferative activity.
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| Kawamura-Tsuzuku J, Suzuki T, Yoshida Y, Yamamoto T.
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| Oncogene 23(39):6630-8.PMID: 15235587 2004
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10 | TOB1
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| Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system.
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| Sasajima H, Nakagawa K, Yokosawa H.
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| Eur J Biochem 269(14):3596-604. 2002
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11 | BTG1, BTG2, BTG3, BTG4, TOB1, TOB2
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| Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system.
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| Sasajima H, Nakagawa K, Yokosawa H.
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| Eur J Biochem 269(14):3596-604.PMID: 12135500 2002
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12 | BTG4, CNOT7, BTG3, TOB1, TOB2
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| Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex.
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| Yoshida Y, Hosoda E, Nakamura T, Yamamoto T.
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| Jpn J Cancer Res 92(6):592-6. 2001
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13 | TOB1
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| Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.
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| Matsuda S, Kawamura-Tsuzuku J, Ohsugi M, Yoshida M, Emi M, Nakamura Y, Onda M, Yoshida Y, Nishiyama A, Yamamoto T.
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| Oncogene 12(4):705-13. 1996
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