| 1 | TNPO1, TNPO3
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| Nonclassical nuclear localization signals mediate nuclear import of CIRBP.
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| Bourgeois B, Hutten S, Gottschalk B, Hofweber M, Richter G, Sternat J, Abou-Ajram C, Göbl C, Leitinger G, Graier WF, Dormann D, Madl T.
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| Proc Natl Acad Sci U S A. Apr 14;117(15):8503-8514. doi: 10.1073/pnas.1918944117. Epub 2020 Mar 31. 2020
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| 2 | LGMD1F, TNPO3
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| Novel mutation in TNPO3 causes congenital limb-girdle myopathy with slow progression.
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| Vihola A, Palmio J, Danielsson O, Penttilä S, Louiselle D, Pittman S, Weihl C, Udd B.
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| Neurol Genet 5(3):e337. doi: 10.1212/NXG.0000000000000337. eCollection 2019 Jun.
2019
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| 3 | LGMD1F, TNPO3
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| The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection.
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| Rodríguez-Mora S, De Wit F, García-Perez J, Bermejo M, López-Huertas MR, Mateos E, Martí P, Rocha S, Vigón L, Christ F, Debyser Z, Vílchez JJ, Coiras M, Alcamí J.
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| PLoS Pathog 15(8):e1007958. doi: 10.1371/journal.ppat.1007958. eCollection 2019 Aug.
2019
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| 4 | LGMD1F, TNPO3
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| A novel pathogenic variant in TNPO3 in a Hungarian family with limb-girdle muscular dystrophy 1F.
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| Pál E, Zima J, Hadzsiev K, Ito YA, Hartley T; Care4Rare Canada Consortium, Boycott KM, Melegh B.
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| Eur J Med Genet 62(7):103662. doi: 10.1016/j.ejmg.2019.05.001. Epub 2019 May 6.
2019
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| 5 | CPSF6, TNPO3
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| Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.
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| Jang S, Cook NJ, Pye VE, Bedwell GJ, Dudek AM, Singh PK, Cherepanov P, Engelman AN.
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| Nucleic Acids Res 47(9):4663-4683. doi: 10.1093/nar/gkz206. 2019
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| 6 | IRF5, TNPO3
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| The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
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| Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S; UK Primary Sjögren's Syndrome Registry, Rischmueller M, Lester S, Brun JG, Gřransson LG, Harboe E, Omdal R, Cunninghame-Graham DS, Vyse T, Miceli-Richard C, Brennan MT, Lessard JA, Wahren-Herlenius M, Kvarnström M, Illei GG, Witte T, Jonsson R, Eriksson P, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Anaya JM, Rhodus NL, Segal BM, Merrill JT, James JA, Guthridge JM, Scofield RH, Alarcon-Riquelme M, Bae SC, Boackle SA, Criswell LA, Gilkeson G, Kamen DL, Jacob CO, Kimberly R, Brown E, Edberg J, Alarcón GS, Reveille JD, Vilá LM, Petri M, Ramsey-Goldman R, Freedman BI, Niewold T, Stevens AM, Tsao BP, Ying J, Mayes MD, Gorlova OY, Wakeland W, Radstake T, Martin E, Martin J, Siminovitch K, Moser Sivils KL, Gaffney PM, Langefeld CD, Harley JB, Kaufman KM.
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| Hum Mol Genet 24(2):582-96. doi: 10.1093/hmg/ddu455. Epub 2014 Sep 8.
2015
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| 7 | TNPO3
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| Structural basis for nuclear import of splicing factors by human Transportin 3.
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| Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Öztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, KewalRamani VN, Fassati A, Engelman A, Cherepanov P.
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| Proc Natl Acad Sci U S A 111(7):2728-33. doi: 10.1073/pnas.1320755111. Epub 2014 Jan 21.
2014
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| 8 | TNPO3
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| Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase.
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| Taltynov O, Demeulemeester J, Christ F, De Houwer S, Tsirkone VG, Gerard M, Weeks SD, Strelkov SV, Debyser Z.
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| J Biol Chem 288(35):25603-13. doi: 10.1074/jbc.M113.484345. Epub 2013 Jul 22.
2013
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| 9 | CPSF6, TNPO3
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| The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6.
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| Fricke T, Valle-Casuso JC, White TE, Brandariz-Nuńez A, Bosche WJ, Reszka N, Gorelick R, Diaz-Griffero F.
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| Retrovirology 10:46. doi: 10.1186/1742-4690-10-46.
2013
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| 10 | TNPO3
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| Identification of residues in the C-terminal domain of HIV-1 integrase that mediate binding to the transportin-SR2 protein.
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| De Houwer S, Demeulemeester J, Thys W, Taltynov O, Zmajkovicova K, Christ F, Debyser Z.
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| J Biol Chem 287(41):34059-68. doi: 10.1074/jbc.M112.387944. Epub 2012 Aug 7.
2012
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| 11 | TNPO3
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| The cargo-binding domain of transportin 3 is required for lentivirus nuclear import.
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| Logue EC, Taylor KT, Goff PH, Landau NR.
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| J Virol 85(24):12950-61. doi: 10.1128/JVI.05384-11. Epub 2011 Oct 5.
2011
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| 12 | IL12A, IRF5, SPIB, TNPO3
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| Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.
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| Liu X, Invernizzi P, Lu Y, Kosoy R, Lu Y, Bianchi I, Podda M, Xu C, Xie G, Macciardi F, Selmi C, Lupoli S, Shigeta R, Ransom M, Lleo A, Lee AT, Mason AL, Myers RP, Peltekian KM, Ghent CN, Bernuzzi F, Zuin M, Rosina F, Borghesio E, Floreani A, Lazzari R, Niro G, Andriulli A, Muratori L, Muratori P, Almasio PL, Andreone P, Margotti M, Brunetto M, Coco B, Alvaro D, Bragazzi MC, Marra F, Pisano A, Rigamonti C, Colombo M, Marzioni M, Benedetti A, Fabris L, Strazzabosco M, Portincasa P, Palmieri VO, Tiribelli C, Croce L, Bruno S, Rossi S, Vinci M, Prisco C, Mattalia A, Toniutto P, Picciotto A, Galli A, Ferrari C, Colombo S, Casella G, Morini L, Caporaso N, Colli A, Spinzi G, Montanari R, Gregersen PK, Heathcote EJ, Hirschfield GM, Siminovitch KA, Amos CI, Gershwin ME, Seldin MF.
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| Nat Genet 42(8):658-60. Epub 2010 Jul 18.PMID: 20639880 2010
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| 13 | TNPO3
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| The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase.
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| Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A.
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| J Virol 84(1):397-406. Epub 2009 Oct 21.PMID: 19846519 2010
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| 14 | IRF5, MMEL1, TNPO3
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| Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis.
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| Hirschfield GM, Liu X, Han Y, Gorlov IP, Lu Y, Xu C, Lu Y, Chen W, Juran BD, Coltescu C, Mason AL, Milkiewicz P, Myers RP, Odin JA, Luketic VA, Speiciene D, Vincent C, Levy C, Gregersen PK, Zhang J, Heathcote EJ, Lazaridis KN, Amos CI, Siminovitch KA.
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| Nat Genet 42(8):655-7. Epub 2010 Jul 18.PMID: 20639879 2010
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| 15 | TNPO3
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| HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase.
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| Luban J.
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| Curr Biol 18(16):R710-3.PMID: 1872790 2008
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| 16 | TNPO3
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| A conserved Drosophila transportin-serine/arginine-rich (SR) protein permits nuclear import of Drosophila SR protein splicing factors and their antagonist repressor splicing factor 1.
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| Allemand E, Dokudovskaya S, Bordonne R, Tazi J.
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| Mol Biol Cell 13(7):2436-47. 2002
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| 17 | TNPO3
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| A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins.
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| Lai MC, Lin RI, Huang SY, Tsai CW, Tarn WY.
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| J Biol Chem 275(11):7950-7. 2000
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| 18 | TNPO3
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| Transportin-SR, a nuclear import receptor for SR proteins.
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| Kataoka N, Bachorik JL, Dreyfuss G.
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| J Cell Biol 145(6):1145-52. 1999
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