Citations for
1CMH7, TNNI3
Hypertrophic Cardiomyopathy Accompanied by Spinocerebellar Atrophy With a Novel Mutation in Troponin I Gene.
Kawai H, Morimoto S, Takakuwa Y, Ueda A, Inada K, Sarai M, Arimura T, Mutoh T, Kimura A, Ozaki Y.
Int Heart J 57(4):507-10. doi: 10.1536/ihj.15-444. 2016
2TNNI1, TNNI2, TNNI3
TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.
Sheng JJ, Jin JP.
Gene 576(1 Pt 3):385-94. doi: 10.1016/j.gene.2015.10.052. Review. 2016
3CAMK2A, TNNI3
CaMKII-dependent myofilament Ca2+ desensitization contributes to the frequency-dependent acceleration of relaxation.
Guilbert A, Lim HJ, Cheng J, Wang Y.
Cell Calcium 58(5):489-99. doi: 10.1016/j.ceca.2015.08.001. 2015
4TNNC1, TNNI3
The cardiac-specific N-terminal region of troponin I positions the regulatory domain of troponin C.
Hwang PM, Cai F, Pineda-Sanabria SE, Corson DC, Sykes BD.
Proc Natl Acad Sci U S A 111(40):14412-7. doi: 10.1073/pnas.1410775111. 2014
5TNNC1, TNNI3
Regulatory domain of troponin moves dynamically during activation of cardiac muscle.
Sevrieva I, Knowles AC, Kampourakis T, Sun YB.
J Mol Cell Cardiol 75:181-7. doi: 10.1016/j.yjmcc.2014.07.015. 2014
6CMH7, TNNI3
Pediatric restrictive cardiomyopathy due to a heterozygous mutation of the TNNI3 gene.
Chen Y, Yang S, Li J, Wang G, Qin Y, Wang D, Cao K.
J Biomed Res 28(1):59-63. doi: 10.7555/JBR.28.20120105. 2014
7TNNI3
Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.
Zhou W, Suntharalingam K, Brand NJ, Barton PJ, Vilar R, Ying L.
PLoS One 8(1):e53137. doi: 10.1371/journal.pone.0053137. 2013
8CMH7, TNNI3
Homozygous mutation in the cardiac troponin I gene: clinical heterogeneity in hypertrophic cardiomyopathy.
Gray B, Yeates L, Medi C, Ingles J, Semsarian C.
Int J Cardiol 168(2):1530-1. doi: 10.1016/j.ijcard.2012.12.008. No abstract available. 2013
9TNNI3
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Wijnker PJ, Foster DB, Tsao AL, Frazier AH, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J.
Am J Physiol Heart Circ Physiol 304(2):H260-8. doi: 10.1152/ajpheart.00498.2012. 2013
10TNNC1, TNNI3
Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation.
Wang D, Robertson IM, Li MX, McCully ME, Crane ML, Luo Z, Tu AY, Daggett V, Sykes BD, Regnier M.
Biochemistry 51(22):4473-87. 2012
11TNNI3
AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.
Oliveira SM, Zhang YH, Solis RS, Isackson H, Bellahcene M, Yavari A, Pinter K, Davies JK, Ge Y, Ashrafian H, Walker JW, Carling D, Watkins H, Casadei B, Redwood C.
Circ Res 110(9):1192-201. doi: 10.1161/CIRCRESAHA.111.259952. 2012
12TNNC1, TNNI3, TPM1
Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.
Asumda FZ, Chase PB.
Differentiation 83(3):106-15. doi: 10.1016/j.diff.2011.10.002. 2012
13TNNI3
Calcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosin.
Zhang Z, Akhter S, Mottl S, Jin JP.
FEBS J 278(18):3348-59. doi: 10.1111/j.1742-4658.2011.08250.x. 2011
14NPPB, TNNI3
Combined measurements of cardiac troponin I and brain natriuretic peptide are useful for predicting adverse outcomes in hypertrophic cardiomyopathy.
Kubo T, Kitaoka H, Okawa M, Yamanaka S, Hirota T, Baba Y, Hayato K, Yamasaki N, Matsumura Y, Yasuda N, Sugiura T, Doi YL.
Circ J 75(4):919-26. 2011
15TNNC1, TNNI3
The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments.
Galińska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB.
Circ Res 106(4):705-11. Epub 2009 Dec 24. 2010
16TNNI3
[Mutations in sarcomeric genes MYH7, MYBPC3, TNNT2, TNNI3, and TPM1 in patients with hypertrophic cardiomyopathy]
García-Castro M, Coto E, Reguero JR, Berrazueta JR, Alvarez V, Alonso B, Sainz R, Martín M, Morís C.
Rev Esp Cardiol 62(1):48-56. Spanish. 2009
17STK4, TNNI3
Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1.
You B, Yan G, Zhang Z, Yan L, Li J, Ge Q, Jin JP, Sun J.
Biochem J 418(1):93-101.PMID: 18986304 2009
18CMH13, TNNC1, TNNI3
Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy.
Carballo S, Robinson P, Otway R, Fatkin D, Jongbloed JD, de Jonge N, Blair E, van Tintelen JP, Redwood C, Watkins H.
Circ Res 105(4):375-82. Epub 2009 Jul 9. 2009
19TNNI3
Combination of C-reactive protein and cardiac troponin I for predicting adverse cardiac events after sirolimus-eluting stent implantation.
Huang W, Lei H, Liu Q, Ma KH, Qin S, Chang J, Jia FP, He Q, Zuo Z.
Coron Artery Dis 20(3):245-50. 2009
20TNNI3
Prognostic value of elevated cardiac troponin I in ESRD patients with sepsis.
Kang EW, Na HJ, Hong SM, Shin SK, Kang SW, Choi KH, Lee HY, Han DS, Han SH.
Nephrol Dial Transplant 24(5):1568-73. Epub 2009 Jan 14. 2009
21CMD1FF, TNNI3
Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy.
Carballo S, Robinson P, Otway R, Fatkin D, Jongbloed JD, de Jonge N, Blair E, van Tintelen JP, Redwood C, Watkins H.
Circ Res 105(4):375-82. doi: 10.1161/CIRCRESAHA.109.196055. Epub 2009 Jul 9. 2009
22ACTC1, CFMH4, CMH1, CMH11, MYBPC3, MYH7, MYL2, MYL3, PRKAG2, TNNI3, TNNT2, TPM1
Shared genetic causes of cardiac hypertrophy in children and adults.
Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE.
N Engl J Med 358(18):1899-908. Epub 2008 Apr 9. 2008
23RCAN3, TNNI3
Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3).
Canaider S, Facchin F, Griffoni C, Casadei R, Vitale L, Lenzi L, Frabetti F, D'Addabbo P, Carinci P, Zannotti M, Strippoli P.
Gene 372:128-36. Epub 2006 Mar 3. 2006
24TNNI3
Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development.
Gomes AV, Liang J, Potter JD.
J Biol Chem 280(35):30909-15. Epub 2005 Jun 15. 2005
25TNNI3, CMH7
Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy.
Murphy RT, Mogensen J, Shaw A, Kubo T, Hughes S, McKenna WJ.
Lancet 363(9406):371-2. 2004
26TNNI3
Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction, and increased mortality rates in advanced heart failure.
Horwich TB, Patel J, MacLellan WR, Fonarow GC.
Circulation 108(7):833-8. Epub 2003 Aug 11. 2003
27TNNI3
Identification of novel, cardiac-restricted transcription factors binding to a CACC-box within the human cardiac troponin I promoter.
Dellow KA, Bhavsar PK, Brand NJ, Barton PJ.
Cardiovasc Res 50(1):24-33. 2001
28TNNI1, TNNI3, TNNT1, TNNT2
Close physical linkage of human troponin genes: organization, sequence, and expression of the locus encoding cardiac troponin I and slow skeletal troponin T.
Barton PJ, et al.
Genomics 57(1):102-9 1999
29CMH7, TNNI3
Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.
Kimura A, Harada H, Park JE, Nishi H, Satoh M, Takahashi M, Hiroi S, Sasaoka T, Ohbuchi N, Nakamura T, Koyanagi T, Hwang TH, Choo JA, Chung KS, Hasegawa A, Nagai R, Okazaki O, Nakamura H, Matsuzaki M, Sakamoto T, Toshima H, Koga Y, Imaizumi T, Sasazuki T.
Nat Genet 16(4):379-82. 1997
30TNNI3
Assignment of the human cardiac troponin I gene (TNNI3) to chromosome 19q13.4 by radiation hybrid mapping.
Mogensen J, et al.
Cytogenet Cell Genet 79 : 272-273. 1997
31TNNI3
Isolation and characterization of the human cardiac troponin I gene (TNNI3).
Bhavsar PK, et al.
Genomics 35 : 11-23 1996
32TNNI3
Mapping TNNC1, the gene that encodes cardiac troponin I in the human and the mouse.
Bermingham N, et al.
Genomics 30 : 620-622. 1995
33TNNI3
The human cardiac troponin I locus : assignment to chromosome 19p13.2-19q13.2.
MacGeoch C, et al.
Hum Genet 88 : 101-104. 1991
34TNNI3
Molecular cloning of human cardiac troponin I using polymerase chain reaction.
Vallins WJ, et al.
FEBS Lett 270 : 57-61. 1990