| 1 | TNKS, TNKS2, USP25
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| USP25 regulates Wnt signaling by controlling the stability of tankyrases.
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| Xu D, Liu J, Fu T, Shan B, Qian L, Pan L, Yuan J.
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| Genes Dev 31(10):1024-1035. doi: 10.1101/gad.300889.117. Epub 2017 Jun 15.
2017
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| 2 | AXIN1, KIF3A, SLC2A4, TNKS2
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| The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation.
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| Guo HL, Zhang C, Liu Q, Li Q, Lian G, Wu D, Li X, Zhang W, Shen Y, Ye Z, Lin SY, Lin SC.
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| Cell Res 22(8):1246-57. doi: 10.1038/cr.2012.52. Epub 2012 Apr 3.
2012
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| 3 | TNKS, TNKS2
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| Structural basis of selective inhibition of human tankyrases.
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| Narwal M, Venkannagari H, Lehtiö L.
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| J Med Chem 55(3):1360-7. doi: 10.1021/jm201510p. Epub 2012 Jan 25.
2012
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| 4 | RNF146, TNKS, TNKS2
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| Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.
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| Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, Liu PS, Bheddah S, Tao J, Lill JR, Hongo JA, Davis D, Kirkpatrick DS, Polakis P, Costa M.
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| PLoS One 6(7):e22595. Epub 2011 Jul 25.
2011
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| 5 | CRBM, RNF146, SH3BP2, TNKS, TNKS2
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| Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.
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| Levaot N, Voytyuk O, Dimitriou I, Sircoulomb F, Chandrakumar A, Deckert M, Krzyzanowski PM, Scotter A, Gu S, Janmohamed S, Cong F, Simoncic PD, Ueki Y, La Rose J, Rottapel R.
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| Cell 147(6):1324-39. doi: 10.1016/j.cell.2011.10.045.
2011
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| 6 | CRBM, TNKS, TNKS2
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| Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.
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| Guettler S, LaRose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F.
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| Cell 147(6):1340-54. doi: 10.1016/j.cell.2011.10.046. Erratum in: Cell. 2012 Jan 20;148(1-2):376.
2011
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| 7 | TNKS, TNKS2
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| Tankyrase is necessary for canonical Wnt signaling during kidney development.
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| Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, Chen C, Lum L, Carroll TJ.
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| Dev Dyn 239(7):2014-23. doi: 10.1002/dvdy.22340.
2010
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| 8 | TNKS, TNKS2
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| Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.
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| Karlberg T, Markova N, Johansson I, Hammarström M, Schütz P, Weigelt J, Schüler H.
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| J Med Chem 53(14):5352-5. doi: 10.1021/jm100249w. 2010
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| 9 | AXIN1, TNKS, TNKS2
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| Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
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| Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
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| Nature 461(7264):614-20. Epub 2009 Sep 16.
2009
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| 10 | TNKS, TNKS2
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| Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.
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| Shebzukhov YV, Lavrik IN, Karbach J, Khlgatian SV, Koroleva EP, Belousov PV, Kashkin KN, Knuth A, Jager E, Chi NW, Kuprash DV, Nedospasov SA.
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| Cancer Immunol Immunother 57(6):871-81. Epub 2007 Nov 20. 2008
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| 11 | TNKS2
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| Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue.
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| Sidorova N, Zavalishina L, Kurchashova S, Korsakova N, Nazhimov V, Frank G, Kuimov A.
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| Cell Tissue Res 323(1):137-45. Epub 2005 Sep 3.
2006
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| 12 | TERF1, TINF2, PINX1, TNKS, TNKS2
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| Targeted deletion reveals an essential function for the telomere length regulator Trf1.
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| Karlseder J, Kachatrian L, Takai H, Mercer K, Hingorani S, Jacks T, de Lange T.
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| Mol Cell Biol 23(18):6533-41. 2003
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| 13 | TNKS2
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| Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14.
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| Lyons RJ, Deane R, Lynch DK, Ye ZS, Sanderson GM, Eyre HJ, Sutherland GR, Daly RJ.
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| J Biol Chem 276(20):17172-80. 2001
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| 14 | TNKS2
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| Novel tankyrase-related gene detected with meningioma-specific sera.
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| Monz D, Munnia A, Comtesse N, Fischer U, Steudel WI, Feiden W, Glass B, Meese EU.
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| Clin Cancer Res 7(1):113-9. 2001
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| 15 | TNKS2
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| TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.
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| Kaminker PG, Kim SH, Taylor RD, Zebarjadian Y, Funk WD, Morin GB, Yaswen P, Campisi J.
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| J Biol Chem 276(38):35891-9. 2001
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