| 1 | GMDS, TNKS
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| Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase.
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| Eisemann T, Langelier MF, Pascal JM.
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| J Biol Chem. Oct 4;294(40):14574-14590. doi: 10.1074/jbc.RA119.009200. Epub 2019 Aug 2 2019
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| 2 | TNKS, TNKS2, USP25
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| USP25 regulates Wnt signaling by controlling the stability of tankyrases.
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| Xu D, Liu J, Fu T, Shan B, Qian L, Pan L, Yuan J.
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| Genes Dev 31(10):1024-1035. doi: 10.1101/gad.300889.117. Epub 2017 Jun 15.
2017
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| 3 | AMOT, RNF146, TNKS, YAP1
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| Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins.
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| Wang W, Li N, Li X, Tran MK, Han X, Chen J.
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| Cell Rep 13(3):524-32. doi: 10.1016/j.celrep.2015.09.014. Epub 2015 Oct 8.
2015
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| 4 | HEPACAM2, TNKS
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| Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation.
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| Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, Yasunaga S, Takihara Y, Yamamoto T, Izumi S, Ohsugi M, Inaba T.
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| Mol Cell 47(5):694-706. doi: 10.1016/j.molcel.2012.06.033. Epub 2012 Aug 2.
2012
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| 5 | TNKS
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| Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.
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| Casás-Selves M, Kim J, Zhang Z, Helfrich BA, Gao D, Porter CC, Scarborough HA, Bunn PA Jr, Chan DC, Tan AC, DeGregori J.
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| Cancer Res 72(16):4154-64. doi: 10.1158/0008-5472.CAN-11-2848. Epub 2012 Jun 27.
2012
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| 6 | CENPJ, TNKS
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| Tankyrase 1 regulates centrosome function by controlling CPAP stability.
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| Kim MK, Dudognon C, Smith S.
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| EMBO Rep 13(8):724-32. doi: 10.1038/embor.2012.86. Epub 2012 Jun 15.
2012
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| 7 | TNKS, TNKS2
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| Structural basis of selective inhibition of human tankyrases.
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| Narwal M, Venkannagari H, Lehtiö L.
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| J Med Chem 55(3):1360-7. doi: 10.1021/jm201510p. Epub 2012 Jan 25.
2012
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| 8 | AXIN1, TNKS
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| Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment.
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| Morrone S, Cheng Z, Moon RT, Cong F, Xu W.
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| Proc Natl Acad Sci U S A 109(5):1500-5. doi: 10.1073/pnas.1116618109. Epub 2012 Jan 17.
2012
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| 9 | DEL8P23, TNKS
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| Genotype-phenotype correlations in a new case of 8p23.1 deletion and review of the literature.
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| Ballarati L, Cereda A, Caselli R, Selicorni A, Recalcati MP, Maitz S, Finelli P, Larizza L, Giardino D.
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| Eur J Med Genet 54(1):55-9. Epub 2010 Oct 20.
2011
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| 10 | RNF146, TNKS, TNKS2
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| Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.
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| Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, Liu PS, Bheddah S, Tao J, Lill JR, Hongo JA, Davis D, Kirkpatrick DS, Polakis P, Costa M.
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| PLoS One 6(7):e22595. Epub 2011 Jul 25.
2011
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| 11 | CRBM, RNF146, SH3BP2, TNKS, TNKS2
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| Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.
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| Levaot N, Voytyuk O, Dimitriou I, Sircoulomb F, Chandrakumar A, Deckert M, Krzyzanowski PM, Scotter A, Gu S, Janmohamed S, Cong F, Simoncic PD, Ueki Y, La Rose J, Rottapel R.
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| Cell 147(6):1324-39. doi: 10.1016/j.cell.2011.10.045.
2011
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| 12 | CRBM, TNKS, TNKS2
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| Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.
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| Guettler S, LaRose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F.
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| Cell 147(6):1340-54. doi: 10.1016/j.cell.2011.10.046. Erratum in: Cell. 2012 Jan 20;148(1-2):376.
2011
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| 13 | TNKS
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| Tankyrase-1 assembly to large protein complexes blocks its telomeric function.
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| Hatsugai K, Ohishi T, Sugimoto Y, Seimiya H.
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| FEBS Lett 584(18):3885-90. Epub 2010 Aug 7.
2010
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| 14 | TNKS, TNKS2
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| Tankyrase is necessary for canonical Wnt signaling during kidney development.
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| Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, Chen C, Lum L, Carroll TJ.
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| Dev Dyn 239(7):2014-23. doi: 10.1002/dvdy.22340.
2010
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| 15 | TNKS, TNKS2
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| Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.
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| Karlberg T, Markova N, Johansson I, Hammarström M, Schütz P, Weigelt J, Schüler H.
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| J Med Chem 53(14):5352-5. doi: 10.1021/jm100249w. 2010
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| 16 | AXIN1, TNKS, TNKS2
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| Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
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| Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
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| Nature 461(7264):614-20. Epub 2009 Sep 16.
2009
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| 17 | TNKS
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| Polymorphisms in telomere maintenance genes and risk of lung cancer.
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| Choi JE, Kang HG, Jang JS, Choi YY, Kim MJ, Kim JS, Jeon HS, Lee WK, Cha SI, Kim CH, Kam S, Jung TH, Park JY.
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| Cancer Epidemiol Biomarkers Prev 18(10):2773-81. Epub 2009 Sep 22.
2009
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| 18 | NUMA1, TNKS
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| Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly.
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| Chang P, Coughlin M, Mitchison TJ.
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| Mol Biol Cell 20(21):4575-85. Epub 2009 Sep 16.
2009
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| 19 | TNKS
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| Deletion of 8p23.1 with features of Cornelia de Lange syndrome and congenital diaphragmatic hernia and a review of deletions of 8p23.1 to 8pter? A further locus for Cornelia de Lange syndrome.
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| Baynam G, Goldblatt J, Walpole I.
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| Am J Med Genet A 146A(12):1565-70. Review.
2008
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| 20 | TNKS, TNKS2
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| Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.
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| Shebzukhov YV, Lavrik IN, Karbach J, Khlgatian SV, Koroleva EP, Belousov PV, Kashkin KN, Knuth A, Jager E, Chi NW, Kuprash DV, Nedospasov SA.
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| Cancer Immunol Immunother 57(6):871-81. Epub 2007 Nov 20. 2008
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| 21 | TNKS
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| Zinc binding catalytic domain of human tankyrase 1.
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| Lehtiö L, Collins R, van den Berg S, Johansson A, Dahlgren LG, Hammarström M, Helleday T, Holmberg-Schiavone L, Karlberg T, Weigelt J.
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| J Mol Biol 379(1):136-45. Epub 2008 Apr 3.
2008
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| 22 | TNKS
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| Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
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| Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H.
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| Exp Cell Res 314(5):1115-24. Epub 2007 Dec 14.
2008
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| 23 | TNKS
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| The role of the poly(ADP-ribose) polymerase tankyrase1 in telomere length control by the TRF1 component of the shelterin complex.
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| Donigian JR, de Lange T.
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| J Biol Chem 282(31):22662-7. Epub 2007 Jun 8. 2007
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| 24 | PARP1, TNKS
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| Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1.
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| Yeh TY, Sbodio JI, Nguyen MT, Meyer TN, Lee RM, Chi NW.
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| Mol Cell Biochem 276(1-2):183-92. 2005
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| 25 | NUMA1, TNKS
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| NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.
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| Chang W, Dynek JN, Smith S.
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| Biochem J 391(Pt 2):177-84. 2005
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| 26 | TNKS, TERF2, TINF2, PARP1
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| TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex.
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| Ye JZ, de Lange T.
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| Nat Genet 36(6):618-23. Epub 2004 May 09. 2004
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| 27 | TNKS
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| Tankyrase, a positive regulator of telomere elongation, is over expressed in human breast cancer.
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| Gelmini S, Poggesi M, Distante V, Bianchi S, Simi L, Luconi M, Raggi CC, Cataliotti L, Pazzagli M, Orlando C.
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| Cancer Lett 216(1):81-7. 2004
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| 28 | TERF1, TINF2, PINX1, TNKS, TNKS2
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| Targeted deletion reveals an essential function for the telomere length regulator Trf1.
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| Karlseder J, Kachatrian L, Takai H, Mercer K, Hingorani S, Jacks T, de Lange T.
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| Mol Cell Biol 23(18):6533-41. 2003
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| 29 | FNBP1, TNKS
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| The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance.
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| Fuchs U, Rehkamp GF, Slany R, Follo M, Borkhardt A.
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| FEBS Lett 554(1-2):10-6. 2003
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| 30 | MCL1, TNKS
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| Tankyrase 1 interacts with Mcl-1 proteins and inhibits their regulation of apoptosis.
|
| Bae J, Donigian JR, Hsueh AJ.
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| J Biol Chem 278(7):5195-204. Epub 2002 Dec 9. 2003
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| 31 | TNKS
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| Chromosomal mapping of the tankyrase gene in human and mouse.
|
| Zhu L, et al.
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| Genomics 57(2):320-1. No abstract available 1999
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| 32 | TNKS
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| Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.
|
| Smith S, et al.
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| Science 282(5393):1484-7. 1998
|