Citations for
1TNIK
Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.
Lee RS, Zhang L, Berger A, Lawrence MG, Song J, Niranjan B, Davies RG, Lister NL, Sandhu SK, Rubin MA, Risbridger GP, Taylor RA, Rickman DS, Horvath LG, Daly RJ.
Neoplasia 21(4):389-400. doi: 10.1016/j.neo.2019.02.005. Epub 2019 Mar 20. 2019
2MRT54, TNIK
A null mutation in TNIK defines a novel locus for intellectual disability.
Anazi S, Shamseldin HE, AlNaqeb D, Abouelhoda M, Monies D, Salih MA, Al-Rubeaan K, Alkuraya FS.
Hum Genet 135(7):773-8. doi: 10.1007/s00439-016-1671-9. Epub 2016 Apr 22. 2016
3TNIK
TNIK inhibition abrogates colorectal cancer stemness.
Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T.
Nat Commun 7:12586. doi: 10.1038/ncomms12586. 2016
4TNIK
TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer.
Zhang Y, Jiang H, Qin M, Su X, Cao Z, Wang J.
Tumour Biol 37(1):1035-40. doi: 10.1007/s13277-015-3881-5. Epub 2015 Aug 14. 2016
5TNIK
Organization of TNIK in dendritic spines.
Burette AC, Phend KD, Burette S, Lin Q, Liang M, Foltz G, Taylor N, Wang Q, Brandon NJ, Bates B, Ehlers MD, Weinberg RJ.
J Comp Neurol 523(13):1913-24. doi: 10.1002/cne.23770. Epub 2015 Jul 1. 2015
6TNIK
The essential role of TNIK gene amplification in gastric cancer growth.
Yu DH, Zhang X, Wang H, Zhang L, Chen H, Hu M, Dong Z, Zhu G, Qian Z, Fan J, Su X, Xu Y, Zheng L, Dong H, Yin X, Ji Q, Ji J.
Oncogenesis 2:e89. doi: 10.1038/oncsis.2014.2. 2014
7RAP2A, TNIK
Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
Park DS, Seo JH, Hong M, Choi SC.
Biochem Biophys Res Commun 436(2):338-43. doi: 10.1016/j.bbrc.2013.05.104. Epub 2013 Jun 4. 2013
8TNIK
Dynamic change of TNIK in response to tumor necrosis factor alpha in a TRAF2-dependent manner.
Gui J, Li Z, Zhou X.
Hum Cell 26(2):67-72. doi: 10.1007/s13577-012-0058-z. Epub 2013 Jan 26. 2013
9TNIK
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.
Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG.
J Neurosci 32(40):13987-99. doi: 10.1523/JNEUROSCI.2433-12.2012. 2012
10TNIK
The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.
Shkoda A, Town JA, Griese J, Romio M, Sarioglu H, Kn÷fel T, Giehler F, Kieser A.
PLoS Biol 10(8):e1001376. doi: 10.1371/journal.pbio.1001376. Epub 2012 Aug 14. 2012
11TNIK
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.
Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG.
J Neurosci 32(40):13987-99. doi: 10.1523/JNEUROSCI.2433-12.2012. 2012
12TNIK
Enormous influence of TNIK knockdown on intracellular signals and cell survival.
Gui J, Yang B, Wu J, Zhou X.
Hum Cell 24(3):121-6. doi: 10.1007/s13577-011-0023-2. Epub 2011 Jun 28. 2011
13NEDD4, RAP2A, TNIK
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.
Kawabe H, Neeb A, Dimova K, Young SM Jr, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, Rhee J, Brose N.
Neuron 65(3):358-72. doi: 10.1016/j.neuron.2010.01.007. 2010
14RAP2A, RAP2B, RAP2C, TNIK
Rap2 function requires palmitoylation and recycling endosome localization.
Uechi Y, Bayarjargal M, Umikawa M, Oshiro M, Takei K, Yamashiro Y, Asato T, Endo S, Misaki R, Taguchi T, Kariya K.
Biochem Biophys Res Commun 378(4):732-7. Epub 2008 Dec 4. 2009
15TNIK
The kinase TNIK is an essential activator of Wnt target genes.
Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H.
EMBO J 28(21):3329-40. Epub 2009 Oct 8.PMID: 19816403 2009
16MINK1, RAP2A, TANC1, TNIK
MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.
Nonaka H, Takei K, Umikawa M, Oshiro M, Kuninaka K, Bayarjargal M, Asato T, Yamashiro Y, Uechi Y, Endo S, Suzuki T, Kariya K.
Biochem Biophys Res Commun 377(2):573-8. Epub 2008 Oct 18. 2008
17TNIK
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton.
Taira K, Umikawa M, Takei K, Myagmar BE, Shinzato M, Machida N, Uezato H, Nonaka S, Kariya K.
J Biol Chem 279(47):49488-96. Epub 2004 Sep 1. 2004
18TNIK
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton.
Fu CA, Shen M, Huang BC, Lasaga J, Payan DG, Luo Y.
J Biol Chem 274(43):30729-37. 1999