| 1 | SALL4, SLC22A25, SPATC1L, TNFSF13
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| Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study
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| Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M
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| Mol Med Rep. Nov;16(5):5823-5832. doi: 10.3892/mmr.2017.7334. Epub 2017 Aug 23. 2017
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| 2 | TNFSF13
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| High expression of APRIL correlates with poor prognosis in clear cell renal cell carcinoma.
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| Lee C, Park JW, Suh JH, Moon KC.
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| Pathol Res Pract 211(11):824-8. doi: 10.1016/j.prp.2015.07.011. Epub 2015 Jul 20.
2015
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| 3 | TNFSF13, TNFSF13B
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| Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
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| Schuepbach-Mallepell S, Das D, Willen L, Vigolo M, Tardivel A, Lebon L, Kowalczyk-Quintas C, Nys J, Smulski C, Zheng TS, Maskos K, Lammens A, Jiang X, Hess H, Tan SL, Schneider P.
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| J Biol Chem 290(26):16330-42. doi: 10.1074/jbc.M115.661405. Epub 2015 May 7.
2015
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| 4 | TNFSF13
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| APRIL promotes breast tumor growth and metastasis and is associated with aggressive basal breast cancer.
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| García-Castro A, Zonca M, Florindo-Pinheiro D, Carvalho-Pinto CE, Cordero A, Gutiérrez del Fernando B, García-Grande A, Mañes S, Hahne M, González-Suárez E, Planelles L.
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| Carcinogenesis 36(5):574-84. doi: 10.1093/carcin/bgv020. Epub 2015 Mar 6.
2015
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| 5 | FDX1, TNFSF13
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| Genetic polymorphisms in TNFSF13 and FDX1 are associated with IgA nephropathy in the Han Chinese population.
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| Niu D, Gao Y, Xie L, Sun J, Lu W, Jin G, Hao Y, Zhang Y, Yin A, Geng Y, Zhang W, Chen C, Li S.
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| Hum Immunol 76(11):831-5. doi: 10.1016/j.humimm.2015.09.044. Epub 2015 Oct 21.
2015
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| 6 | TNF, TNFRSF17, TNFSF13
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| Expression of TNF-α, APRIL and BCMA in Behcet's disease.
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| Shaker OG, Tawfic SO, El-Tawdy AM, El-Komy MH, El Menyawi M, Heikal AA.
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| J Immunol Res 2014:380405. doi: 10.1155/2014/380405. Epub 2014 Nov 5.
2014
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| 7 | TNFSF13
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| Increased serum APRIL differentially correlates with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients.
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| Boghdadi G, Elewa EA.
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| Rheumatol Int 34(9):1217-23. doi: 10.1007/s00296-014-3020-4. Epub 2014 Apr 21.
2014
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| 8 | TNFSF13
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| Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL.
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| Osório C, Chacón PJ, White M, Kisiswa L, Wyatt S, Rodríguez-Tébar A, Davies AM.
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| Mol Cell Neurosci 59:24-36. doi: 10.1016/j.mcn.2014.01.002. Epub 2014 Jan 18.
2014
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| 9 | IRF8, TNFSF13
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| A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma.
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| Bouamar H, Abbas S, Lin AP, Wang L, Jiang D, Holder KN, Kinney MC, Hunicke-Smith S, Aguiar RC.
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| Blood 122(5):726-33. doi: 10.1182/blood-2013-04-495804. Epub 2013 Jun 17.
2013
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| 10 | TNFSF13
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| The TNF family member APRIL dampens collagen-induced arthritis.
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| Fernandez L, Salinas GF, Rocha C, Carvalho-Pinto CE, Yeremenko N, Papon L, Medema JP, Combe B, Morel J, Baeten D, Hahne M.
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| Ann Rheum Dis 72(8):1367-74. doi: 10.1136/annrheumdis-2012-202382. Epub 2012 Nov 24.
2013
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| 11 | HOXC4, NFKB1, TNFSF13
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| APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells.
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| Park SR, Kim PH, Lee KS, Lee SH, Seo GY, Yoo YC, Lee J, Casali P.
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| Cytokine 61(2):608-13. doi: 10.1016/j.cyto.2012.10.018. Epub 2012 Nov 21.
2013
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| 12 | TNFRSF17, TNFSF13
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| B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies.
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| Alexaki VI, Pelekanou V, Notas G, Venihaki M, Kampa M, Dessirier V, Sabour-Alaoui S, Stathopoulos EN, Tsapis A, Castanas E.
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| Endocrinology 153(2):739-49. doi: 10.1210/en.2011-1504. Epub 2011 Dec 13.
2012
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| 13 | TNFRSF17, TNFSF13
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| APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells.
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| Notas G, Alexaki VI, Kampa M, Pelekanou V, Charalampopoulos I, Sabour-Alaoui S, Pediaditakis I, Dessirier V, Gravanis A, Stathopoulos EN, Tsapis A, Castanas E.
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| J Immunol 189(10):4748-58. doi: 10.4049/jimmunol.1102891. Epub 2012 Oct 15.
2012
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| 14 | TNFSF13, TNFSF13B
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| Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance.
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| Kiyama K, Kawabata D, Hosono Y, Kitagori K, Yukawa N, Yoshifuji H, Omura K, Fujii T, Mimori T.
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| Arthritis Res Ther 14(2):R86. doi: 10.1186/ar3810.
2012
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| 15 | TNFSF13, TNFSF13B
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| APRIL and BAFF proteins increase proliferation of human adipose-derived stem cells through activation of Erk1/2 MAP kinase.
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| Zonca M, Mancheño-Corvo P, DelaRosa O, Mañes S, Büscher D, Lombardo E, Planelles L.
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| Tissue Eng Part A 18(7-8):852-9. doi: 10.1089/ten.TEA.2011.0316. Epub 2011 Dec 22.
2012
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| 16 | TNFRSF17, TNFSF13, TNFSF13B
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| Increased BCMA expression in lupus marks activated B cells, and BCMA receptor engagement enhances the response to TLR9 stimulation.
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| Kim J, Gross JA, Dillon SR, Min JK, Elkon KB.
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| Autoimmunity 44(2):69-81. doi: 10.3109/08916934.2010.509122. Epub 2011 Jan 20.
2011
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| 17 | TNFSF13, TNFSF13B
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| BAFF and APRIL induce inflammatory activation of THP-1 cells through interaction with their conventional receptors and activation of MAPK and NF-κB.
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| Lee SM, Kim EJ, Suk K, Lee WH.
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| Inflamm Res 60(9):807-15. doi: 10.1007/s00011-011-0336-3. Epub 2011 Apr 20.
2011
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| 18 | TNFSF13
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| Macrophages express membrane bound form of APRIL that can generate immunomodulatory signals.
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| Lee SM, Jeon ST, Suk K, Lee WH.
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| Immunology 131(3):350-6. doi: 10.1111/j.1365-2567.2010.03306.x.
2010
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| 19 | TNFSF13, TNFSF13B
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| Serum BAFF and APRIL levels in patients with PBC.
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| Migita K, Ilyassova B, Kovzel EF, Nersesov A, Abiru S, Maeda Y, Komori A, Ito M, Yano K, Yatsuhashi H, Shimoda S, Ishibashi H, Nakamura M.
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| Clin Immunol 134(2):217-25. doi: 10.1016/j.clim.2009.09.007. Epub 2009 Oct 17.
2010
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| 20 | TNFSF13
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| Synovial tissues concentrate secreted APRIL.
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| Gabay C, Krenn V, Bosshard C, Seemayer CA, Chizzolini C, Huard B.
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| Arthritis Res Ther 11(5):R144. doi: 10.1186/ar2817. Epub 2009 Sep 29.
2009
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| 21 | TNFSF13
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| Reduced APRIL expression induces cellular senescence via a HSPG-dependent pathway.
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| Ding W, Ju S, Jiang S, Zhu L, Wang Y, Wang H.
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| Pathol Oncol Res 15(4):693-701. doi: 10.1007/s12253-009-9172-y. Epub 2009 May 26.
2009
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| 22 | TNFRSF13B, TNFRSF17, TNFSF13, TNFSF13B
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| Identification of new splice variants of the genes BAFF and BCMA.
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| Smirnova AS, Andrade-Oliveira V, Gerbase-DeLima M.
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| Mol Immunol 45(4):1179-83. Epub 2007 Sep 6.
2008
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| 23 | TNFSF13
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| TACI regulates IgA production by APRIL in collaboration with HSPG.
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| Sakurai D, Hase H, Kanno Y, Kojima H, Okumura K, Kobata T.
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| Blood 109(7):2961-7. 2007
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| 24 | TNFSF13, TNFSF13B
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| The role of the BAFF/APRIL system on T cell function.
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| Mackay F, Leung H.
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| Semin Immunol 18(5):284-9. Epub 2006 Aug 22. Review.
2006
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| 25 | CVID2, TNFSF13, TNFSF13B, TNFRSF13B
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| Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.
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| Salzer U, Chapel HM, Webster AD, Pan-Hammarstrom Q, Schmitt-Graeff A, Schlesier M, Peter HH, Rockstroh JK, Schneider P, Schaffer AA, Hammarstrom L, Grimbacher B.
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| Nat Genet 37(8):820-8. Epub 2005 Jul 10. 2005
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| 26 | CVID2, TNFSF13, TNFSF13B, TNFRSF13B
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| TACI is mutant in common variable immunodeficiency and IgA deficiency.
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| Castigli E, Wilson SA, Garibyan L, Rachid R, Bonilla F, Schneider L, Geha RS.
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| Nat Genet 37(8):829-34. Epub 2005 Jul 10. 2005
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| 27 | TNFSF13
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| Increased levels of APRIL (a proliferation-inducing ligand) mRNA in multiple sclerosis.
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| Thangarajh M, Masterman T, Rot U, Duvefelt K, Brynedal B, Karrenbauer VD, Hillert J.
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| J Neuroimmunol 167(1-2):210-4. 2005
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| 28 | TNFRSF13B, TNFSF13, TNFSF13B
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| TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS.
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| Gross JA, Dillon SR, Mudri S, Johnston J, Littau A, Roque R, Rixon M, Schou O, Foley KP, Haugen H, McMillen S, Waggie K, Schreckhise RW, Shoemaker K, Vu T, Moore M, Grossman A, Clegg CH.
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| Immunity 15(2):289-302. 2001
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| 29 | TNFSF13
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| APRIL, a new member of the tumor necrosis factor family, modulates death ligand-induced apoptosis.
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| Roth W, Wagenknecht B, Klumpp A, Naumann U, Hahne M, Tschopp J, Weller M.
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| Cell Death Differ 8(4):403-10. 2001
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| 30 | ALOX12, ATP1B2, CD68, CHD3, CHRNB1, EIF4A1, FGF11, FXR2, GUCY2D, KDM6B, NEUROD2, SHBG, TNFSF12, TNFSF13, TP53
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| Physical Map of 17p13 and the Genes Adjacent to p53.
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| Cousin P, Billotte J, Chaubert P, Shaw P.
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| Genomics 63(1):60-68. 2000
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| 31 | TNFRSF13B, TNFSF13, TNFSF13B
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| TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation.
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| Xia XZ, Treanor J, Senaldi G, Khare SD, Boone T, Kelley M, Theill LE, Colombero A, Solovyev I, Lee F, McCabe S, Elliott R, Miner K, Hawkins N, Guo J, Stolina M, Yu G, Wang J, Delaney J, Meng SY, Boyle WJ, Hsu H.
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| J Exp Med 192(1):137-43. 2000
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| 32 | TNFSF13
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| APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.
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| Hahne M, et al.
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| J Exp Med 188(6):1185-90 1998
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