Citations for
1TNFRSF11A, TNFRSF11B, TNFSF11
Expression of osteoprotegerin, RNAK and RANKL genes in femoral head avascular necrosis and related signaling pathway.
Miao Q, Hao S, Li H, Sun F, Wang X.
Int J Clin Exp Pathol 8(9):10460-7. eCollection 2015. 2015
2TNFRSF11A, TNFRSF11B, TNFSF11
Regulation of Osteoblast Migration Involving Receptor Activator of Nuclear Factor-kappa B (RANK) Signaling.
Golden D, Saria EA, Hansen MF.
J Cell Physiol 230(12):2951-60. doi: 10.1002/jcp.25024. 2015
3CTGF, TNFRSF11A, TNFRSF11B, TNFSF11
CCN2 enhances RANKL-induced osteoclast differentiation via direct binding to RANK and OPG.
Aoyama E, Kubota S, Khattab HM, Nishida T, Takigawa M.
Bone 73:242-8. doi: 10.1016/j.bone.2014.12.058. Epub 2014 Dec 30. 2015
4TNFRSF11A, TNFRSF11B, TNFSF11
Potential role of the OPG/RANK/RANKL axis in prostate cancer invasion and bone metastasis.
Li X, Liu Y, Wu B, Dong Z, Wang Y, Lu J, Shi P, Bai W, Wang Z.
Oncol Rep 32(6):2605-11. doi: 10.3892/or.2014.3511. Epub 2014 Sep 23. 2014
5TNFRSF11A, TNFRSF11B, TNFSF11
Expression profile of osteoprotegerin, RANK and RANKL genes in the femoral head of patients with avascular necrosis.
Samara S, Dailiana Z, Chassanidis C, Koromila T, Papatheodorou L, Malizos KN, Kollia P.
Exp Mol Pathol 96(1):9-14. doi: 10.1016/j.yexmp.2013.10.014. Epub 2013 Nov 5. 2014
6TNFRSF11B, TNFSF11
Expression of RANKL/OPG during bone remodeling in vivo.
Tanaka H, Mine T, Ogasa H, Taguchi T, Liang CT.
Biochem Biophys Res Commun. 411(4):690-4. 2011
7ESR1, ESR2, LRP4, LRP5, SOST, TNFRSF11A, TNFRSF11B, TNFSF11, VDR, WLS
Genetics of osteoporosis: accelerating pace in gene identification and validation.
Li WF, Hou SX, Yu B, Li MM, Férec C, Chen JM.
Hum Genet 127(3):249-85. Epub 2009 Dec 12. Review.PMID: 20101412 2010
8TNFRSF11B
Mesenchymal stem cells-derived vascular smooth muscle cells release abundant levels of osteoprotegerin.
Corallini F, Gonelli A, D'Aurizio F, di Iasio MG, Vaccarezza M.
Eur J Histochem 53(1):19-24. 2009
9TNFRSF11B
Osteoprotegerin Lys3Asn polymorphism and the risk of fracture in older women.
Moffett SP, Oakley JI, Cauley JA, Lui LY, Ensrud KE, Taylor BC, Hillier TA, Hochberg MC, Li J, Cayabyab S, Lee JM, Peltz G, Cummings SR, Zmuda JM; Study of Osteoporotic Fractures Research Group.
J Clin Endocrinol Metab 93(5):2002-8. Epub 2008 Mar 4. 2008
10TNFRSF11B
The association of osteoprotegerin gene polymorphisms with periodontitis.
Park OJ, Shin SY, Choi Y, Kim MH, Chung CP, Ku Y, Kim KK.
Oral Dis 14(5):440-4. 2008
11TNFRSF11B, ANKH
Osteoprotegerin plasma levels are strongly associated with polymorphisms in human homologue of the mouse progressive ankylosis (ANKH) gene.
Vistoropsky Y, Malkin I, Kobyliansky E, Livshits G.
Ann Hum Genet 71(Pt 3):302-7. Epub 2006 Nov 28. 2007
12TNFRSF11B
Osteoprotegerin expression in dendritic cells increases with maturation and is NF-kappaB-dependent.
Schoppet M, Henser S, Ruppert V, Stübig T, Al-Fakhri N, Maisch B, Hofbauer LC.
J Cell Biochem 100(6):1430-9. 2007
13TNFRSF11A, TNFRSF11B, TNFSF11
Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modulates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells.
Mori K, Berreur M, Blanchard F, Chevalier C, Guisle-Marsollier I, Masson M, Rédini F, Heymann D.
Oncol Rep 18(6):1365-71. 2007
14TNFRSF11B, TNFSF11, TNFRSF11A
Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men.
Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X.
Hum Genet 118(5):568-77. Epub 2005 Oct 26. 2006
15PDB5, TNFRSF11B
Deletion of aspartate 182 in OPG causes juvenile Paget's disease by impairing both protein secretion and binding to RANKL.
Middleton-Hardie C, Zhu Q, Cundy H, Lin JM, Callon K, Tong PC, Xu J, Grey A, Cornish J, Naot D.
J Bone Miner Res 21(3):438-45. Epub 2005 Nov 14. 2006
16TNFSF11, TNFRSF11B
The RANKL/OPG system and bone mineral density in patients with chronic liver disease.
Moschen AR, Kaser A, Stadlmann S, Millonig G, Kaser S, Muhllechner P, Habior A, Graziadei I, Vogel W, Tilg H.
J Hepatol 43(6):973-83. Epub 2005 Jul 5. 2005
17TNFRSF11B
Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor.
Zannettino AC, Holding CA, Diamond P, Atkins GJ, Kostakis P, Farrugia A, Gamble J, To LB, Findlay DM, Haynes DR.
J Cell Physiol. 204(2):714-23. 2005
18TNFRSF11B
Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease.
Kiechl S, Schett G, Wenning G, Redlich K, Oberhollenzer M, Mayr A, Santer P, Smolen J, Poewe W, Willeit J.
Circulation 109(18):2175-80. Epub 2004 Apr 26. 2004
19TNFRSF11B
Osteoprotegerin gene polymorphisms in men with coronary artery disease.
Soufi M, Schoppet M, Sattler AM, Herzum M, Maisch B, Hofbauer LC, Schaefer JR.
J Clin Endocrinol Metab 89(8):3764-8. 2004
20TNFRSF11B
Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin.
Daroszewska A, Hocking LJ, McGuigan FE, Langdahl B, Stone MD, Cundy T, Nicholson GC, Fraser WD, Ralston SH.
J Bone Miner Res 19(9):1506-11. Epub 2004 Jun 14. 2004
21SQSTM1, TNFRSF11A, TNFRSF11B
Genetic regulation of osteoclast development and function.
Teitelbaum SL, Ross FP.
Nat Rev Genet 4(8):638-49. Review. 2003
22PDB5, TNFRSF11B
Idiopathic hyperphosphatasia and TNFRSF11B mutations: relationships between phenotype and genotype.
Chong B, Hegde M, Fawkner M, Simonet S, Cassinelli H, Coker M, Kanis J, Seidel J, Tau C, Tuysuz B, Yuksel B, Love D; International Hyperphosphatasia Collaborative Group.
J Bone Miner Res 18(12):2095-104. 2003
23PDB5, TNFRSF11B
Genetic control of bone remodeling--insights from a rare disease.
Krane SM.
N Engl J Med 347(3):210-2. No abstract available. 2002
24PDB5, TNFRSF11B
A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype.
Cundy T, Hegde M, Naot D, Chong B, King A, Wallace R, Mulley J, Love DR, Seidel J, Fawkner M, Banovic T, Callon KE, Grey AB, Reid IR, Middleton-Hardie CA, Cornish J.
Hum Mol Genet 11(18):2119-27. 2002
25TNFRSF11B
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells.
Holen I, Croucher PI, Hamdy FC, Eaton CL.
Cancer Res 62(6):1619-23. 2002
26TNFRSF11B
A single nucleotide polymorphism in the promoter region of the human gene for osteoprotegerin is related to vascular morphology and function.
Brandstrom H, Stiger F, Lind L, Kahan T, Melhus H, Kindmark A.
Biochem Biophys Res Commun 293(1):13-7. 2002
27TNFRSF11B
Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures.
Langdahl BL, Carstens M, Stenkjaer L, Eriksen EF.
J Bone Miner Res 17(7):1245-55. 2002
28TNFSF11, CALCA, TNFRSF11B
Isolation of human osteoclasts formed in vitro: hormonal effects on the bone-resorbing activity of human osteoclasts.
Kudo O, Sabokbar A, Pocock A, Itonaga I, Athanasou NA.
Calcif Tissue Int 71(6):539-46. Epub 2002 Sep 18. 2002
29TNFRSF11B
Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression.
Wan M, Shi X, Feng X, Cao X.
J Biol Chem 276(13):10119-25. 2001
30RUNX2, TGFB1, TNFRSF11B
Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects.
Thirunavukkarasu K, Miles RR, Halladay DL, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.
J Biol Chem 276(39):36241-50. 2001
31IFNG, TNFRSF11A, TNFRSF11B, TRAF6
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.
Takayanagi H, Ogasawara K, Hida S, Chiba T, Murata S, Sato K, Takaoka A, Yokochi T, Oda H, Tanaka K, Nakamura K, Taniguchi T.
Nature 408(6812):600-5. 2000
32IL1B, TNFRSF11B, TNFSF11
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells.
Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S.
Bone 25(3):255-9 1999
33TNFRSF11B
Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis-inhibitory factor.
Morinaga T, et al.
Eur J Biochem 254 : 685-691. 1998
34TNFRSF11B
OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40.
Yun TJ, et al.
J Immunol 161 : 6113-6121. 1998
35TNFRSF11B
Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG) : a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro.
Yasuda H, et al.
Endocrinology 139 : 1329-1337. 1998
36TNFRSF11B, TNFSF11
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL.
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T.
Proc Natl Acad Sci U S A. 95(7):3597-602. 1998
37TNFRSF11B
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
Bucay N, Sarosi I, Dunstan CR, Morony S, Tarpley J, Capparelli C, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, Simonet WS.
Genes Dev. 12(9):1260-8. 1998
38TNFRSF11B
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin.
Mizuno A, Amizuka N, Irie K, Murakami A, Fujise N, Kanno T, Sato Y, Nakagawa N, Yasuda H, Mochizuki S, Gomibuchi T, Yano K, Shima N, Washida N, Tsuda E, Morinaga T, Higashio K, Ozawa H.
Biochem Biophys Res Commun. 247(3):610-5. 1998
39TNFRSF11B
Osteoprotegerin : a novel secreted protein involved in the regulation of bone density.
Simonet WS, et al.
Cell 89 : 309-319. 1997
40TNFRSF11B
Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis.
Tsuda E, Goto M, Mochizuki S, Yano K, Kobayashi F, Morinaga T, Higashio K.
Biochem Biophys Res Commun. 234(1):137-42. 1997