| 1 | TNFRSF10A, TNFRSF10B
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| Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation.
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| Micheau O.
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| Int J Mol Sci. Mar 2;19(3):715. doi: 10.3390/ijms19030715. 2018
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| 2 | DDIT3, KAT2A, TNFRSF10A, TNFRSF10B
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| DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells.
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| Li T, Su L, Lei Y, Liu X, Zhang Y, Liu X.
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| J Biol Chem. Apr 24;290(17):11108-18. doi: 10.1074/jbc.M115.645333. Epub 2015 Mar 13. 2015
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| 3 | TNFRSF10A, TNFRSF10B, TNFSF10, TNK2
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| Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death.
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| Linderoth E, Pilia G, Mahajan NP, Ferby I.
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| J Biol Chem 288(46):32922-31. doi: 10.1074/jbc.M113.481507. Epub 2013 Oct 1.
2013
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| 4 | MARCHF1, MARCHF8, TNFRSF10A
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| Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1
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| van de Kooij B, Verbrugge I, de Vries E, Gijsen M, Montserrat V, Maas C, Neefjes J, Borst J.
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| J Biol Chem. Mar 1;288(9):6617-28. doi: 10.1074/jbc.M112.448209. Epub 2013 Jan 8. 2013
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| 5 | GLI3, TNFRSF10A, TNFSF10
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| GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.
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| Kurita S, Mott JL, Almada LL, Bronk SF, Werneburg NW, Sun SY, Roberts LR, Fernandez-Zapico ME, Gores GJ.
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| Oncogene 29(34):4848-58. Epub 2010 Jun 21. 2010
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| 6 | TNFRSF10A, TNFRSF10B, TNFSF10
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| Post-translational modification of TRAIL receptor type 1 on various tumor cells and the susceptibility of tumors to TRAIL-induced apoptosis.
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| Lin Z, Jin A, Ozawa T, Tajiri K, Obata T, Ishida I, Jin F, Kishi H, Muraguchi A.
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| Biochem Biophys Res Commun 395(2):251-7. Epub 2010 Apr 2.PMID: 20363213 2010
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| 7 | TNFRSF10A, TNFRSF10B, TNFSF10
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| TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5.
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| Lemke J, Noack A, Adam D, Tchikov V, Bertsch U, Röder C, Schütze S, Wajant H, Kalthoff H, Trauzold A.
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| J Mol Med 88(7):729-40. Epub 2010 Mar 31.PMID: 20354842 2010
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| 8 | TNFRSF10A, TNFRSF10B
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| TRAIL-induced apoptosis and expression of death receptor TRAIL-R1 and TRAIL-R2 in bladder cancer cells.
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| Szliszka E, Mazur B, Zydowicz G, Czuba ZP, Król W.
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| Folia Histochem Cytobiol 47(4):579-85.PMID: 20430723 2009
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| 9 | TNFRSF10A
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| TRAIL-R1 polymorphisms and cancer susceptibility: an evidence-based meta-analysis.
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| Chen B, Liu S, Wang XL, Xu W, Li Y, Zhao WH, Wu JQ.
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| Eur J Cancer 45(14):2598-605. Epub 2009 Jul 28. Review.PMID: 19643596 2009
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| 10 | TNFRSF10A, TNFRSF10B, TNFSF10
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| TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
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| Oikonomou E, Kosmidou V, Katseli A, Kothonidis K, Mourtzoukou D, Kontogeorgos G, Andera L, Zografos G, Pintzas A.
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| Int J Cancer 125(9):2127-35.PMID: 19637313 2009
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| 11 | TNFRSF10A, TNFRSF10B, TNFSF10
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| TRAIL receptor mediates inflammatory cytokine release in an NF-kappaB-dependent manner.
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| Tang W, Wang W, Zhang Y, Liu S, Liu Y, Zheng D.
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| Cell Res 19(6):758-67.PMID: 19434100 2009
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| 12 | ARAP1, TNFRSF10A
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| Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.
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| Símová S, Klíma M, Cermak L, Sourková V, Andera L.
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| Apoptosis 13(3):423-36.
2008
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| 13 | TNFRSF10A
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| Alpha-tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: implication for sensitisation of resistant cancer cells to TRAIL apoptosis.
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| Tomasetti M, Andera L, Alleva R, Borghi B, Neuzil J, Procopio A.
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| FEBS Lett 580(8):1925-31. Epub 2006 Feb 28. 2006
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| 14 | TNFRSF10A
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| Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer.
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| Wolf S, Mertens D, Pscherer A, Schroeter P, Winkler D, Grone HJ, Hofele C, Hemminki K, Kumar R, Steineck G, Dohner H, Stilgenbauer S, Lichter P.
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| Int J Cancer 118(7):1831-5. 2006
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| 15 | TNFRSF10A
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| Evidence that the human death receptor 4 is regulated by activator protein 1.
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| Guan B, Yue P, Lotan R, Sun SY.
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| Oncogene 21(20):3121-9. 2002
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| 16 | TNFRSF10A, TNFRSF10B, TNFRSF10C, TNFRSF10D
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| Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance.
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| Ozoren N, Fisher MJ, Kim K, Liu CX, Genin A, Shifman Y, Dicker DT, Spinner NB, Lisitsyn NA, El-Deiry WS.
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| Int J Oncol 16(5):917-25. 2000
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| 17 | TNFRSF10A
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| The receptor for the cytotoxic ligand TRAIL.
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| Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM.
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| Science 276(5309):111-3. 1997
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| 18 | TNFRSF10A, TNFRSF10B, TNFRSF10C
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| Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL.
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| MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES.
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| J Biol Chem 272(41):25417-20. 1997
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| 19 | TNFRSF10A, TNFRSF10B
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| TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
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| Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T, Holler N, Tschopp J.
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| Immunity 7(6):831-6. 1997
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