| 1 | MACC1, RELA, TNF
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| Pro-inflammatory TNF-α and IFN-γ Promote Tumor Growth and Metastasis via Induction of MACC1
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| Kobelt D, Zhang C, Clayton-Lucey IA, Glauben R, Voss C, Siegmund B, Stein U.
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| Front Immunol. May 27;11:980. doi: 10.3389/fimmu.2020.00980. 2020
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| 2 | CCL4, TNF
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| TNF-α Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-κB Signaling Pathways.
|
| Ahmad R, Kochumon S, Chandy B, Shenouda S, Koshy M, Hasan A, Arefanian H, Al-Mulla F, Sindhu S.
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| Cell Physiol Biochem 52(4):908-921. doi: 10.33594/000000063.
2019
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| 3 | CHRM3, EGFR, MAPK14, TNF
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| Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPK.
|
| Uwada J, Yazawa T, Islam MT, Khan MRI, Krug SM, Fromm M, Karaki SI, Suzuki Y, Kuwahara A, Yoshiki H, Sada K, Muramatsu I, Taniguchi T.
|
| Cell Signal 35:188-196. doi: 10.1016/j.cellsig.2017.04.007. Epub 2017 Apr 12.
2017
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| 4 | HDAC7, TNF
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| HDAC7 modulates TNF-α-mediated suppression of Leydig cell steroidogenesis.
|
| Sadasivam M, Ramatchandirin B, Balakrishnan S, Prahalathan C.
|
| Mol Cell Biochem ol Cell Biochem. 2015 Apr 28. [Epub ahead of print]
2015
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| 5 | KRT18, KRT8, TNF
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| Tumor necrosis factor-α confers cardioprotection through ectopic expression of keratins K8 and K18.
|
| Papathanasiou S, Rickelt S, Soriano ME, Schips TG, Maier HJ, Davos CH, Varela A, Kaklamanis L, Mann DL, Capetanaki Y.
|
| Nat Med 21(9):1076-84. doi: 10.1038/nm.3925. Epub 2015 Aug 17.
2015
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| 6 | MFGE8, TNF
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| Tumor necrosis factor α up-regulates endometrial milk fat globule-epidermal growth factor 8 protein production via nuclear factor κB activation, resulting in cell migration of epithelial cells.
|
| Yu L, Anderson S, Oehninger S, Bocca S.
|
| Fertil Steril 101(2):552-9. doi: 10.1016/j.fertnstert.2013.10.032. Epub 2013 Nov 18.
2014
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| 7 | TNF, TNFRSF13, TNFRSF13B, TNFRSF17
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| Expression of TNF-α, APRIL and BCMA in Behcet's disease.
|
| Shaker OG, Tawfic SO, El-Tawdy AM, El-Komy MH, El Menyawi M, Heikal AA.
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| J Immunol Res 2014:380405. doi: 10.1155/2014/380405. Epub 2014 Nov 5.
2014
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| 8 | TNF, TNFRSF17, TNFSF13
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| Expression of TNF-α, APRIL and BCMA in Behcet's disease.
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| Shaker OG, Tawfic SO, El-Tawdy AM, El-Komy MH, El Menyawi M, Heikal AA.
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| J Immunol Res 2014:380405. doi: 10.1155/2014/380405. Epub 2014 Nov 5.
2014
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| 9 | CASP8, PAWR, TNF
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| Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis.
|
| Treude F, Kappes F, Fahrenkamp D, Müller-Newen G, Dajas-Bailador F, Krämer OH, Lüscher B, Hartkamp J.
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| Oncotarget 5(10):2988-98.
2014
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| 10 | ADM, TNF
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| Serum levels of adrenomedullin and inflammatory cytokines in women with term idiopathic intrauterine growth restriction.
|
| Elfayomy AK, Habib FA, Almasry SM, Safwat MD, Eldomiaty MA.
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| J Obstet Gynaecol 33(2):135-9. doi: 10.3109/01443615.2012.721821.
2013
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| 11 | DUSP4, TNF
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| Tumor necrosis factor-α-mediated suppression of dual-specificity phosphatase 4: crosstalk between NFκB and MAPK regulates endothelial cell survival.
|
| Kao DD, Oldebeken SR, Rai A, Lubos E, Leopold JA, Loscalzo J, Handy DE.
|
| Mol Cell Biochem 382(1-2):153-62. doi: 10.1007/s11010-013-1730-7. Epub 2013 Jun 28.
2013
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| 12 | RHBDF2, TNF
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| iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
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| McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW.
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| Science 335(6065):229-32. 2012
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| 13 | TNF
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| A molecular mechanism for TNF-α-mediated downregulation of B cell responses.
|
| Frasca D, Romero M, Diaz A, Alter-Wolf S, Ratliff M, Landin AM, Riley RL, Blomberg BB.
|
| J Immunol 188(1):279-86. Epub 2011 Nov 23.
2012
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| 14 | ICAM1, ITLN1, TNF, VCAM1
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| Omentin inhibits TNF-α-induced expression of adhesion molecules in endothelial cells via ERK/NF-κB pathway.
|
| Zhong X, Li X, Liu F, Tan H, Shang D.
|
| Biochem Biophys Res Commun 425(2):401-6. doi: 10.1016/j.bbrc.2012.07.110. Epub 2012 Jul 27.
2012
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| 15 | MMP9, MTOR, TNF
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| TNF-α promotes human retinal pigment epithelial (RPE) cell migration by inducing matrix metallopeptidase 9 (MMP-9) expression through activation of Akt/mTORC1 signaling.
|
| Wang CH, Cao GF, Jiang Q, Yao J.
|
| Biochem Biophys Res Commun 425(1):33-8. doi: 10.1016/j.bbrc.2012.07.044. Epub 2012 Jul 20.
2012
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| 16 | CLU, MMP9, TNF
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| Clusterin induces the secretion of TNF-α and the chemotactic migration of macrophages.
|
| Shim YJ, Kang BH, Choi BK, Park IS, Min BH.
|
| Biochem Biophys Res Commun 422(1):200-5. doi: 10.1016/j.bbrc.2012.04.162. Epub 2012 May 7.
2012
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| 17 | LEP, RETN, TNF
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| Serum leptin, resistin and TNF-α levels in patients with systemic sclerosis: the role of adipokines in scleroderma.
|
| Pehlivan Y, Onat AM, Ceylan N, Turkbeyler IH, Buyukhatipoglu H, Comez G, Babacan T, Tarakcioglu M.
|
| Int J Rheum Dis 15(4):374-9. doi: 10.1111/j.1756-185X.2012.01755.x. Epub 2012 Jun 29.
2012
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| 18 | NPNT, TNF
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| Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α.
|
| Tsukasaki M, Yamada A, Suzuki D, Aizawa R, Miyazono A, Miyamoto Y, Suzawa T, Takami M, Yoshimura K, Morimura N, Yamamoto M, Kamijo R.
|
| Biochem Biophys Res Commun 410(4):766-70. Epub 2011 Jun 12.
2011
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| 19 | TNF
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| Pathogenic and protective functions of TNF in neuroinflammation are defined by its expression in T lymphocytes and myeloid cells.
|
| Kruglov AA, Lampropoulou V, Fillatreau S, Nedospasov SA.
|
| J Immunol 187(11):5660-70. Epub 2011 Nov 4.
2011
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| 20 | TNF
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| Monocyte-specific accessibility of a matrix attachment region in the tumor necrosis factor locus.
|
| Biglione S, Tsytsykova AV, Goldfeld AE.
|
| J Biol Chem 286(51):44126-33. Epub 2011 Oct 25.
2011
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| 21 | TNF, UBD
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| FAT10 mediates the effect of TNF-α in inducing chromosomal instability.
|
| Ren J, Wang Y, Gao Y, Mehta SB, Lee CG.
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| J Cell Sci 124(Pt 21):3665-75. Epub 2011 Oct 24.
2011
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| 22 | TNF
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| Age-related loss of CpG methylation in the tumour necrosis factor promoter.
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| Gowers IR, Walters K, Kiss-Toth E, Read RC, Duff GW, Wilson AG.
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| Cytokine 56(3):792-7. Epub 2011 Oct 17.
2011
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| 23 | CSP8, TNF
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| Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.
|
| Günther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, Waldner MJ, Hedrick SM, Tenzer S, Neurath MF, Becker C.
|
| Nature 477(7364):335-9. doi: 10.1038/nature10400.
2011
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| 24 | FANCD2, TNF
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| Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.
|
| Matsushita N, Endo Y, Sato K, Kurumizaka H, Yamashita T, Takata M, Yanagi S.
|
| PLoS One 6(8):e23324. Epub 2011 Aug 31.
2011
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| 25 | TNF
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| The role of Tumor Necrosis Factor-alpha (TNF-α) in the pathogenesis of systemic lupus erythematosus.
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| Postal M, Appenzeller S.
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| Cytokine 56(3):537-43. Epub 2011 Sep 9. Review.
2011
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| 26 | CSF2, TNF
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| GM-CSF and TNFα modulate protein expression of human neutrophils visualized by fluorescence two-dimensional difference gel electrophoresis.
|
| Langereis JD, Franciosi L, Ulfman LH, Koenderman L.
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| Cytokine 56(2):422-9. Epub 2011 Aug 27.
2011
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| 27 | TNF, TNFSF12
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| The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB.
|
| Moreno JA, Izquierdo MC, Sanchez-Niño MD, Suárez-Alvarez B, Lopez-Larrea C, Jakubowski A, Blanco J, Ramirez R, Selgas R, Ruiz-Ortega M, Egido J, Ortiz A, Sanz AB.
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| J Am Soc Nephrol 22(7):1315-25. Epub 2011 Jun 30.
2011
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| 28 | TNF
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| TNF mediates the sustained activation of Nrf2 in human monocytes.
|
| Rushworth SA, Shah S, MacEwan DJ.
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| J Immunol 187(2):702-7. Epub 2011 Jun 13. Erratum in: J Immunol. 2011 Dec 1;187(11):6160.
2011
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| 29 | MSX2, TNF
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| Msx2 is required for TNF-α-induced canonical Wnt signaling in 3T3-L1 preadipocytes.
|
| Qadir AS, Lee HL, Baek KH, Park HJ, Woo KM, Ryoo HM, Baek JH.
|
| Biochem Biophys Res Commun 408(3):399-404. doi: 10.1016/j.bbrc.2011.04.029. Epub 2011 Apr 13.
2011
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| 30 | TNF
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| Tumor necrosis factor-α signaling maintains the ability of cortical synapses to express synaptic scaling.
|
| Steinmetz CC, Turrigiano GG.
|
| J Neurosci 30(44):14685-90.
2010
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| 31 | TNF
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| Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells.
|
| Bhatnagar S, Panguluri SK, Gupta SK, Dahiya S, Lundy RF, Kumar A.
|
| PLoS One 5(10):e13262.
2010
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| 32 | IL10, TNF
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| IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.
|
| Smallie T, Ricchetti G, Horwood NJ, Feldmann M, Clark AR, Williams LM.
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| J Exp Med 207(10):2081-8. Epub 2010 Aug 30.
2010
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| 33 | IL10, TNF
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| IL-10 and TNF-alpha promoter polymorphisms in susceptibility to systemic lupus erythematosus in Taiwan.
|
| Lin YJ, Wan L, Huang CM, Sheu JJ, Chen SY, Lin TH, Chen DY, Hsueh KC, Lai CC, Tsai FJ.
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| Clin Exp Rheumatol 28(3):318-24. Epub 2010 Jun 23.
2010
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| 34 | TNF
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| Tumor necrosis factor alpha induces LIF expression through ERK1/2 activation in mammary epithelial cells.
|
| Levy CS, Slomiansky V, Gattelli A, Nahmod K, Pelisch F, Blaustein M, Srebrow A, Coso OA, Kordon EC.
|
| J Cell Biochem 110(4):857-65.
2010
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| 35 | IL6, LEP, STEAP4, TNF
|
| STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.
|
| Chen X, Zhu C, Ji C, Zhao Y, Zhang C, Chen F, Gao C, Zhu J, Qian L, Guo X.
|
| Int J Mol Med 25(3):361-7.
2010
|
| 36 | IGFBP3, RXRA, TNF
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| IGFBP-3, hypoxia and TNF-alpha inhibit adiponectin transcription.
|
| Zappalà G, Rechler MM.
|
| Biochem Biophys Res Commun 382(4):785-9. Epub 2009 Mar 24.
2009
|
| 37 | MAP3K7, TNF
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| TAK1 activation for cytokine synthesis and proliferation of endometriotic cells.
|
| Taniguchi F, Harada T, Miyakoda H, Iwabe T, Deura I, Tagashira Y, Miyamoto A, Watanabe A, Suou K, Uegaki T, Terakawa N.
|
| Mol Cell Endocrinol 307(1-2):196-204. Epub 2009 May 3.
2009
|
| 38 | RFK, TNF
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| Riboflavin kinase couples TNF receptor 1 to NADPH oxidase.
|
| Yazdanpanah B, Wiegmann K, Tchikov V, Krut O, Pongratz C, Schramm M, Kleinridders A, Wunderlich T, Kashkar H, Utermöhlen O, Brüning JC, Schütze S, Krönke M.
|
| Nature 460(7259):1159-63. Epub 2009 Jul 29. 2009
|
| 39 | RIPK1, TNF, TRADD, TRAF2
|
| Up-regulated renal expression of TNF-alpha signalling adapter proteins in lupus glomerulonephritis.
|
| Zhu L, Yang X, Ji Y, Chen W, Guan W, Zhou SF, Yu X.
|
| Lupus 18(2):116-27.
2009
|
| 40 | IL15, TNF
|
| Tumor necrosis factor-alpha enhances IL-15-induced natural killer cell differentiation.
|
| Lee J, Lee SH, Shin N, Jeong M, Kim MS, Kim MJ, Yoon SR, Chung JW, Kim TD, Choi I.
|
| Biochem Biophys Res Commun 386(4):718-23. doi: 10.1016/j.bbrc.2009.06.120. Epub 2009 Jun 25.
2009
|
| 41 | IL1A, IL1B, IL6, TNF
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| Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts.
|
| Turner NA, Das A, Warburton P, O'Regan DJ, Ball SG, Porter KE.
|
| Am J Physiol Heart Circ Physiol 297(3):H1117-27. doi: 10.1152/ajpheart.00372.2009. Epub 2009 Jul 31.
2009
|
| 42 | CELF1, DMPK, TNF
|
| The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy.
|
| Zhang L, Lee JE, Wilusz J, Wilusz CJ.
|
| J Biol Chem 283(33):22457-63. Epub 2008 Jun 16. 2008
|
| 43 | LOX, TNF
|
| Lysyl oxidase (LOX) down-regulation by TNFalpha: a new mechanism underlying TNFalpha-induced endothelial dysfunction.
|
| Rodríguez C, Alcudia JF, Martínez-González J, Raposo B, Navarro MA, Badimon L.
|
| Atherosclerosis 196(2):558-64. Epub 2007 Aug 1.
2008
|
| 44 | IL10, TNF
|
| IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro.
|
| Müller RD, John T, Kohl B, Oberholzer A, Gust T, Hostmann A, Hellmuth M, Laface D, Hutchins B, Laube G, Veh RW, Tschoeke SK, Ertel W, Schulze-Tanzil G.
|
| Cytokine 44(3):377-85. Epub 2008 Nov 20.
2008
|
| 45 | CASP3, GLRX, TNF
|
| Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-alpha-induced cell death.
|
| Sykes MC, Mowbray AL, Jo H.
|
| Circ Res 100(2):152-4. 2007
|
| 46 | IKBKB, MTOR, TNF, TSC1
|
| IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.
|
| Lee DF, Kuo HP, Chen CT, Hsu JM, Chou CK, Wei Y, Sun HL, Li LY, Ping B, Huang WC, He X, Hung JY, Lai CC, Ding Q, Su JL, Yang JY, Sahin AA, Hortobagyi GN, Tsai FJ, Tsai CH, Hung MC.
|
| Cell 130(3):440-55. 2007
|
| 47 | TNF
|
| Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis.
|
| Medica I, Kastrin A, Maver A, Peterlin B.
|
| J Hum Genet 52(10):836-47. Epub 2007 Sep 4. 2007
|
| 48 | ACE, APOE, CHRNB2, CST3, ESR1, GAPDHS, IDE, MTHFR, NCSTN, PRNP, PSEN1, TF, TFAM, TNF
|
| Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
|
| Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE.
|
| Nat Genet 39(1):17-23. 2007
|
| 49 | TNF
|
| TNFalpha mediates the skeletal effects of thyroid-stimulating hormone.
|
| Hase H, Ando T, Eldeiry L, Brebene A, Peng Y, Liu L, Amano H, Davies TF, Sun L, Zaidi M, Abe E.
|
| Proc Natl Acad Sci U S A 103(34):12849-54. Epub 2006 Aug 14. 2006
|
| 50 | IL1B, TCIM, TNF
|
| TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells.
|
| Kim Y, Kim J, Park J, Bang S, Jung Y, Choe J, Song K, Lee I.
|
| FEBS Lett 580(14):3519-24. Epub 2006 May 22. 2006
|
| 51 | TNF
|
| Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases.
|
| Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M.
|
| Cell 120(5):649-61. 2005
|
| 52 | TNF
|
| A role for tumour necrosis factor alpha in human small bowel iron transport.
|
| Sharma N, Laftah AH, Brookes MJ, Cooper B, Iqbal T, Tselepis C.
|
| Biochem J 390(Pt 2):437-46. 2005
|
| 53 | LRRFIP1,TNF
|
| GCF2/LRRFIP1 represses tumor necrosis factor alpha expression.
|
| Suriano AR, Sanford AN, Kim N, Oh M, Kennedy S, Henderson MJ, Dietzmann K, Sullivan KE.
|
| Mol Cell Biol 25(20):9073-81. 2005
|
| 54 | MAP3K7, MAP3K3, RIPK1, TNF
|
| TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation.
|
| Blonska M, Shambharkar PB, Kobayashi M, Zhang D, Sakurai H, Su B, Lin X.
|
| J Biol Chem 280(52):43056-63. Epub 2005 Oct 31. 2005
|
| 55 | TNF
|
| Association of tumor necrosis factor polymorphisms with asthma and serum total IgE.
|
| Shin HD, Park BL, Kim LH, Jung JH, Wang HJ, Kim YJ, Park HS, Hong SJ, Choi BW, Kim DJ, Park CS.
|
| Hum Mol Genet 13(4):397-403. Epub 2003 Dec 17. 2004
|
| 56 | TNF, TLR4
|
| TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury.
|
| Barber RC, Aragaki CC, Rivera-Chavez FA, Purdue GF, Hunt JL, Horton JW.
|
| J Med Genet 41(11):808-13. 2004
|
| 57 | LITAF, TNF
|
| Identification and functional characterization of a novel binding site on TNF-alpha promoter.
|
| Tang X, Fenton MJ, Amar S.
|
| Proc Natl Acad Sci U S A 100(7):4096-101. Epub 2003 Mar 24. 2003
|
| 58 | BID, CASP8, DIABLO, MAPK8, TNF
|
| A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
|
| Deng Y, Ren X, Yang L, Lin Y, Wu X.
|
| Cell 115(1):61-70. 2003
|
| 59 | TNF, TRPC1
|
| Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells.
|
| Paria BC, Malik AB, Kwiatek AM, Rahman A, May MJ, Ghosh S, Tiruppathi C.
|
| J Biol Chem 278(39):37195-203. Epub 2003 Jul 10. 2003
|
| 60 | TNF
|
| Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-kappaB transcription factors.
|
| Van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D.
|
| Hum Mol Genet 11(11):1281-9. 2002
|
| 61 | EIF2AK2 , TNF
|
| Protein kinase R regulates double-stranded RNA induction of TNF-alpha but not IL-1 beta mRNA in human epithelial cells.
|
| Meusel TR, Kehoe KE, Imani F.
|
| J Immunol 168(12):6429-35. 2002
|
| 62 | ADIPOQ, TNF
|
| Identification of regulatory elements in the human adipose most abundant gene transcript-1 ( apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways.
|
| Barth N, Langmann T, Scholmerich J, Schmitz G, Schaffler A.
|
| Diabetologia 45(10):1425-33. Epub 2002 Jul 04. Erratum in: Diabetologia. 2004 Jan;47(1):153. 2002
|
| 63 | TNFSF13B , TNF
|
| An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.
|
| Schiemann B, Gommerman JL, Vora K, Cachero TG, Shulga-Morskaya S, Dobles M, Frew E, Scott ML.
|
| Science 293(5537):2111-4. 2001
|
| 64 | TNF
|
| Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study.
|
| McCusker SM, Curran MD, Dynan KB, McCullagh CD, Urquhart DD, Middleton D, Patterson CC, McIlroy SP, Passmore AP.
|
| Lancet 357(9254):436-9. 2001
|
| 65 | CREBBP, TNF
|
| A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
|
| Falvo JV, Brinkman BM, Tsytsykova AV, Tsai EY, Yao TP, Kung AL, Goldfeld AE.
|
| Proc Natl Acad Sci U S A 97(8):3925-9. 2000
|
| 66 | TIA1, TNF
|
| TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha.
|
| Piecyk M, Wax S, Beck AR, Kedersha N, Gupta M, Maritim B, Chen S, Gueydan C, Kruys V, Streuli M, Anderson P.
|
| EMBO J 19(15):4154-4163. 2000
|
| 67 | TNF
|
| Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma.
|
| Winchester EC, Millwood IY, Rand L, Penny MA, Kessling AM.
|
| Hum Genet 107(6):591-6. 2000
|
| 68 | TNF
|
| Genetic analysis of the 3' untranslated region of the tumour necrosis factor shows a highly conserved region in rheumatoid arthritis affected and unaffected subjects.
|
| Waldron-Lynch F, et al.
|
| J Med Genet 36 : 214-216. 1999
|
| 69 | MALA1, TNF
|
| A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria.
|
| Knight JC, et al.
|
| Nat Genet 22(2):145-50. 1999
|
| 70 | TNF
|
| A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha.
|
| Skoog T, et al.
|
| Hum Mol Genet 8(8):1443-9. 1999
|
| 71 | TNF
|
| TNFA and TNFB polymorphisms in myasthenia gravis.
|
| Skeie GO, et al.
|
| Arch Neurol 56(4):457-61. 1999
|
| 72 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
|
| Sequence diversity in 36 candidate genes for cardiovascular disorders.
|
| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
|
| Am J Hum Genet 65(1):183-91. 1999
|
| 73 | TNF, IGF1
|
| A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide.
|
| Venters HD, et al.
|
| Proc Natl Acad Sci U S A 96(17):9879-84 1999
|
| 74 | TNF, IGF1
|
| Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor-1.
|
| Loddick SA, et al.
|
| Proc Natl Acad Sci U S A 96(17):9449-51. Review. No abstract available 1999
|
| 75 | TNF
|
| Genetic polymorphisms at the tumour necrosis factor loci (TNFA and TNFB) in cardiac sarcoidosis.
|
| Takashige N, Naruse TK, Matsumori A, Hara M, Nagai S, Morimoto S, Hiramitsu S, Sasayama S, Inoko H.
|
| Tissue Antigens 54(2):191-3 1999
|
| 76 | TNF
|
| Significant association of a single nucleotide polymorphism in the tumor necrosis factor-alpha (TNF-alpha) gene promoter with human narcolepsy.
|
| Hohjoh H, Nakayama T, Ohashi J, Miyagawa T, Tanaka H, Akaza T, Honda Y, Juji T, Tokunaga K.
|
| Tissue Antigens 54(2):138-45 1999
|
| 77 | TNF
|
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| 78 | TNF
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| Polymorphism within the tumor necrosis factor alpha (TNF) promoter region in patients with ankylosing spondylitis.
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| Kaijzel EL, Brinkman BM, van Krugten MV, Smith L, Huizinga TW, Verjans GM, Breedveld FC, Verweij CL.
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| Hum Immunol 60(2):140-4. 1999
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| 79 | SLC2A4, TNF
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| Insulin resistance in cancer patients is associated with enhanced tumor necrosis factor-alpha expression in skeletal muscle.
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| Biochem Biophys Res Commun 253(3):887-92. 1998
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| 80 | MAPK8, MAP2K6, TNF
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| Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha.
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| J Biol Chem 273(17):10232-9. 1998
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| 81 | TNF
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| Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter.
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| Tissue Antigens 52(4):359-67. 1998
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| 82 | LTB, TNF
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| Tumour necrosis factor haplotypes and asthma.
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| Hum Mol Genet 6 : 551-554. 1997
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| 83 | ADAM17, TNF
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| A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
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| Nature 385 : 729-733. 1997
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| 84 | TNF, ADAM17
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| Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.
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| Nature 385(6618):733-6. 1997
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| 85 | LST1, TNF, NCR3
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| Complex expression pattern of the TNF region gene LST1 through differential regulation, initiation, and alternative splicing.
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| de Baey A, Fellerhoff B, Maier S, Martinozzi S, Weidle U, Weiss EH.
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| Genomics 45(3):591-600. 1997
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| 86 | TNF
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| An intragenic polymorphism in the human tumor necrosis factor alpha (TNFA) chain-encoding gene.
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| Immunogenetics 44 : 321-322. 1996
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| 87 | DDX39B, FKBP1P1, KRT18P1, LST1, LTA, LTB, MICA, MICB, NCR3, NFKBIL1, PPIAP9, TNF
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| Genes in a 220-kb region spanning the TNF cluster in human MHC.
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| Genomics 31(2):215-22. 1996
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| 88 | TNF
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| Detection of a C-insertion polymorphism within the human tumor necrosis factor alpha (TNFA) gene.
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| Hum Genet 96 : 493. 1995
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| 89 | LTB, LTA, TNF
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| Highly informative typing of the human TNF locus using six adjacent polymorphic markers.
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| Udalova IA, et al.
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| Genomics 16 : 180-186. 1993
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| 90 | TNF
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| Single base polymorphism in the human tumour necrosis factor alpha (TNFalpha) gene detectable by NcoI restriction of PCR product.
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| Hum Mol Genet 1 : 353. 1992
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| 91 | IL6, IL1B, TNF
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| Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease.
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| Dig Dis Sci 37(6):818-26. 1992
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| 92 | TNF
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| An STS in the human TNF locus located at 6p21.3.
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| Nucleic Acids Res 19 : 4784. 1991
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| 93 | ABHD16A, BAG6, BAT2, BAT4, BAT@, D6S51, D6S52, D6S53, D6S81E, DDX39B, LTA, LTB, TNF
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| A new cluster of genes within the human major histocompatibility complex.
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| Spies T, Blanck G, Bresnahan M, Sands J, Strominger JL.
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| Science 243(4888):214-7. 1989
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| 94 | LTB, LTA, TNF
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| Tumor necrosis factor-alpha gene maps between the HLA class III and class I regions as determined by large DNA gel electrophoresis.
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| 95 | LTB, TNF
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| Linkage of TNF genes to the HLA-B locus.
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| Inoko H, et al.
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| Nucleic Acids Res 15 : 8957-8962. 1987
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| 96 | MHC1, MHC2, TNF, LTA
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| Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.
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| Carroll MC, et al.
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| Proc Natl Acad Sci U S A 84 : 8535-8539. 1987
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| 97 | LTA, TNF
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| Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex.
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| Spies T, et al.
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| Proc Natl Acad Sci U S A 83 : 8699-8702. 1986
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| 98 | LTB, LTA, TNF
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| The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 in the mouse.
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| Nedospasov SA, et al.
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| Nucleic Acids Res 14 : 7713-7725. 1986
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| 99 | LTA, LTB, TNF
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| Human lymphotoxin and tumor necrosis factor genes : structure, homology and chromosomal localization.
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