1 | CORO1C, PLS3, SMA, TMOD3
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| The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype.
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| Hosseinibarkooie S, Peters M, Torres-Benito L, Rastetter RH, Hupperich K, Hoffmann A, Mendoza-Ferreira N, Kaczmarek A, Janzen E, Milbradt J, Lamkemeyer T, Rigo F, Bennett CF, Guschlbauer C, Büschges A, Hammerschmidt M, Riessland M, Kye MJ, Clemen CS, Wirth B.
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| Am J Hum Genet 99(3):647-65. doi: 10.1016/j.ajhg.2016.07.014. Epub 2016 Aug 4.
2016
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2 | TMOD1, TMOD2, TMOD3
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| Tropomyosin-binding properties modulate competition between tropomodulin isoforms.
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| Colpan M, Moroz NA, Gray KT, Cooper DA, Diaz CA, Kostyukova AS.
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| Arch Biochem Biophys 600:23-32. doi: 10.1016/j.abb.2016.04.006. Epub 2016 Apr 26.
2016
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3 | TMOD3
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| Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis.
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| Sui Z, Nowak RB, Sanada C, Halene S, Krause DS, Fowler VM.
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| Blood 126(4):520-30. doi: 10.1182/blood-2014-09-601484. Epub 2015 May 11.
2015
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4 | AKT2, SLC2A4, TMOD3
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| Tropomodulin3 as the link between insulin-activated AKT2 and cortical actin remodeling in preparation of GLUT4 exocytosis.
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| Lim CY, Han W.
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| Bioarchitecture 4(6):210-4. doi: 10.1080/19490992.2015.1031949. Epub 2015 Aug 17.
2014
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5 | TMOD1, TMOD3
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| Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3.
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| Lewis RA, Yamashiro S, Gokhin DS, Fowler VM.
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| Cytoskeleton (Hoboken) 71(7):395-411. doi: 10.1002/cm.21179. Epub 2014 Jul 2.
2014
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6 | TMOD1, TMOD2, TMOD3
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| Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes.
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| Guillaud L, Gray KT, Moroz N, Pantazis C, Pate E, Kostyukova AS.
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| Biochemistry 53(16):2689-700. doi: 10.1021/bi401431k. Epub 2014 Apr 18.
2014
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7 | TMOD1, TMOD3
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| Differential actin-regulatory activities of Tropomodulin1 and Tropomodulin3 with diverse tropomyosin and actin isoforms.
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| Yamashiro S, Gokhin DS, Sui Z, Bergeron SE, Rubenstein PA, Fowler VM.
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| J Biol Chem 289(17):11616-29. doi: 10.1074/jbc.M114.555128. Epub 2014 Mar 18.
2014
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8 | TMOD1, TMOD2, TMOD3
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| Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver.
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| Sui Z, Nowak RB, Bacconi A, Kim NE, Liu H, Li J, Wickrema A, An XL, Fowler VM.
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| Blood 123(5):758-67. doi: 10.1182/blood-2013-03-492710. Epub 2013 Oct 24.
2014
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9 | TMOD1, TMOD3, TMOD4
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| Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers.
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| Ochala J, Gokhin DS, Iwamoto H, Fowler VM.
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| FASEB J 28(1):408-15. doi: 10.1096/fj.13-239640. Epub 2013 Sep 26.
2014
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10 | TMOD1, TMOD2, TMOD3
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| Alteration of tropomyosin-binding properties of tropomodulin-1 affects its capping ability and localization in skeletal myocytes.
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| Moroz NA, Novak SM, Azevedo R, Colpan M, Uversky VN, Gregorio CC, Kostyukova AS.
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| J Biol Chem 288(7):4899-907. doi: 10.1074/jbc.M112.434522. Epub 2012 Dec 27.
2013
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11 | STOML2, TMOD3, TPM3
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| Identification and validation of novel serum markers for early diagnosis of endometriosis.
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| Gajbhiye R, Sonawani A, Khan S, Suryawanshi A, Kadam S, Warty N, Raut V, Khole V.
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| Hum Reprod 27(2):408-17. doi: 10.1093/humrep/der410. Epub 2011 Dec 8.
2012
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12 | TMOD3
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| The sarcoplasmic reticulum: Actin and tropomodulin hit the links.
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| Gokhin DS, Fowler VM.
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| Bioarchitecture 1(4):175-179. Epub 2011 Jul 1.
2011
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13 | TMOD1, TMOD2, TMOD3, TMOD4
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| Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.
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| Gokhin DS, Lewis RA, McKeown CR, Nowak RB, Kim NE, Littlefield RS, Lieber RL, Fowler VM.
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| J Cell Biol 189(1):95-109. 2010
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14 | TMOD1, TMOD3
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| Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton.
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| Moyer JD, Nowak RB, Kim NE, Larkin SK, Peters LL, Hartwig J, Kuypers FA, Fowler VM.
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| Blood 116(14):2590-9. doi: 10.1182/blood-2010-02-268458. Epub 2010 Jun 28.
2010
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15 | TMOD1, TMOD3, TMOD4
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| Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities.
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| Yamashiro S, Speicher KD, Speicher DW, Fowler VM.
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| J Biol Chem 285(43):33265-80. doi: 10.1074/jbc.M110.144873. Epub 2010 Jul 21.
2010
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16 | TMOD3
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| Tmod3 regulates polarized epithelial cell morphology.
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| Weber KL, Fischer RS, Fowler VM.
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| J Cell Sci 120(Pt 20):3625-32.
2007
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17 | TMOD3
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| Tropomodulin 3 binds to actin monomers.
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| Fischer RS, Yarmola EG, Weber KL, Speicher KD, Speicher DW, Bubb MR, Fowler VM.
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| J Biol Chem 281(47):36454-65. Epub 2006 Oct 1.
2006
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18 | TMOD3
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| Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility.
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| Fischer RS, Fritz-Six KL, Fowler VM.
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| J Cell Biol 161(2):371-80. Epub 2003 Apr 21.
2003
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19 | LMOD1, LMOD2, TMOD1, TMOD2, TMOD3
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| Leiomodins: larger members of the tropomodulin (Tmod) gene family.
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| Conley CA, Fritz-Six KL, Almenar-Queralt A, Fowler VM.
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| Genomics 73(2):127-39. 2001
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20 | TMOD2, TMOD3, TMOD4
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| Sequencing, Expression Analysis, and Mapping of Three Unique Human Tropomodulin Genes and Their Mouse Orthologs.
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| Cox PR, Zoghbi HY.
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| Genomics 63(1):97-107. 2000
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