Citations for
1TMOD1, TMOD2, TMOD3
Tropomyosin-binding properties modulate competition between tropomodulin isoforms.
Colpan M, Moroz NA, Gray KT, Cooper DA, Diaz CA, Kostyukova AS.
Arch Biochem Biophys 600:23-32. doi: 10.1016/j.abb.2016.04.006. Epub 2016 Apr 26. 2016
2LMOD2, LMOD3, TMOD1, TMOD4
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.
Gokhin DS, Ochala J, Domenighetti AA, Fowler VM.
Development 142(24):4351-62. doi: 10.1242/dev.129171. Epub 2015 Nov 19. 2015
3TMOD1, TMOD3
Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3.
Lewis RA, Yamashiro S, Gokhin DS, Fowler VM.
Cytoskeleton (Hoboken) 71(7):395-411. doi: 10.1002/cm.21179. Epub 2014 Jul 2. 2014
4TMOD1, TMOD2, TMOD3
Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes.
Guillaud L, Gray KT, Moroz N, Pantazis C, Pate E, Kostyukova AS.
Biochemistry 53(16):2689-700. doi: 10.1021/bi401431k. Epub 2014 Apr 18. 2014
5TMOD1, TMOD3
Differential actin-regulatory activities of Tropomodulin1 and Tropomodulin3 with diverse tropomyosin and actin isoforms.
Yamashiro S, Gokhin DS, Sui Z, Bergeron SE, Rubenstein PA, Fowler VM.
J Biol Chem 289(17):11616-29. doi: 10.1074/jbc.M114.555128. Epub 2014 Mar 18. 2014
6TMOD1, TMOD2, TMOD3
Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver.
Sui Z, Nowak RB, Bacconi A, Kim NE, Liu H, Li J, Wickrema A, An XL, Fowler VM.
Blood 123(5):758-67. doi: 10.1182/blood-2013-03-492710. Epub 2013 Oct 24. 2014
7TMOD1, TMOD3, TMOD4
Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers.
Ochala J, Gokhin DS, Iwamoto H, Fowler VM.
FASEB J 28(1):408-15. doi: 10.1096/fj.13-239640. Epub 2013 Sep 26. 2014
8TMOD1, TMOD2, TMOD3
Alteration of tropomyosin-binding properties of tropomodulin-1 affects its capping ability and localization in skeletal myocytes.
Moroz NA, Novak SM, Azevedo R, Colpan M, Uversky VN, Gregorio CC, Kostyukova AS.
J Biol Chem 288(7):4899-907. doi: 10.1074/jbc.M112.434522. Epub 2012 Dec 27. 2013
9TMOD1, TMOD2
Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension.
Moroz N, Guillaud L, Desai B, Kostyukova AS.
PeerJ 1:e7. doi: 10.7717/peerj.7. Print 2013. 2013
10TMOD1
Identification of residues within tropomodulin-1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes.
Tsukada T, Kotlyanskaya L, Huynh R, Desai B, Novak SM, Kajava AV, Gregorio CC, Kostyukova AS.
J Biol Chem 286(3):2194-204. Epub 2010 Nov 15. 2011
11TMOD1, TMOD2
Tropomodulins are negative regulators of neurite outgrowth.
Fath T, Fischer RS, Dehmelt L, Halpain S, Fowler VM.
Eur J Cell Biol 90(4):291-300. doi: 10.1016/j.ejcb.2010.10.014. Epub 2010 Dec 10. 2011
12TMOD1
Erythrocyte tropomodulin isoforms with and without the N-terminal actin-binding domain.
Yao W, Sung LA.
J Biol Chem 285(41):31408-17. Epub 2010 Jul 30. 2010
13LMOD2, TMOD1
Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle.
Tsukada T, Pappas CT, Moroz N, Antin PB, Kostyukova AS, Gregorio CC.
J Cell Sci 123(Pt 18):3136-45. Epub 2010 Aug 24. 2010
14LMOD2, TMOD1
Different localizations and cellular behaviors of leiomodin and tropomodulin in mature cardiomyocyte sarcomeres.
Skwarek-Maruszewska A, Boczkowska M, Zajac AL, Kremneva E, Svitkina T, Dominguez R, Lappalainen P.
Mol Biol Cell 21(19):3352-61. Epub 2010 Aug 4. 2010
15TMOD1, TMOD2, TMOD3, TMOD4
Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.
Gokhin DS, Lewis RA, McKeown CR, Nowak RB, Kim NE, Littlefield RS, Lieber RL, Fowler VM.
J Cell Biol 189(1):95-109. 2010
16TMOD1, TMOD3
Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton.
Moyer JD, Nowak RB, Kim NE, Larkin SK, Peters LL, Hartwig J, Kuypers FA, Fowler VM.
Blood 116(14):2590-9. doi: 10.1182/blood-2010-02-268458. Epub 2010 Jun 28. 2010
17TMOD1, TMOD3, TMOD4
Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities.
Yamashiro S, Speicher KD, Speicher DW, Fowler VM.
J Biol Chem 285(43):33265-80. doi: 10.1074/jbc.M110.144873. Epub 2010 Jul 21. 2010
18TMOD1
Specific expression of E-Tmod (Tmod1) in horizontal cells: implications in neuronal cell mechanics and glaucomatous retina.
Yao W, Sung LA.
Mol Cell Biomech 6(1):71-82. 2009
19TMOD1
Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development.
McKeown CR, Nowak RB, Moyer J, Sussman MA, Fowler VM.
Circ Res 103(11):1241-8. Epub 2008 Oct 16. 2008
20TMOD1, WNT5A
Induced expression of the transcription of tropomodulin 1 by Wnt5a and characterization of the tropomodulin 1 promoter.
Yun S, Rim Y, Jho EH.
Biochem Biophys Res Commun 363(3):727-32. Epub 2007 Sep 20. 2007
21TMOD1
Leucine 135 of tropomodulin-1 regulates its association with tropomyosin, its cellular localization, and the integrity of sarcomeres.
Kong KY, Kedes L.
J Biol Chem 281(14):9589-99. Epub 2006 Jan 23. 2006
22TMOD1
Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1.
Greenfield NJ, Kostyukova AS, Hitchcock-DeGregori SE.
Biophys J 88(1):372-83. Epub 2004 Oct 8. 2005
23TMOD1
Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction.
Vera C, Lao J, Hamelberg D, Sung LA.
Arch Biochem Biophys 444(2):130-8. Epub 2005 Oct 27. 2005
24TMOD1
Cytoplasmic nuclear transfer of the actin-capping protein tropomodulin.
Kong KY, Kedes L.
J Biol Chem 279(29):30856-64. Epub 2004 Apr 29. 2004
25TMOD1
Effect of the structure of the N terminus of tropomyosin on tropomodulin function.
Kostyukova AS, Hitchcock-DeGregori SE.
J Biol Chem 279(7):5066-71. Epub 2003 Dec 2. 2004
26LMOD1, LMOD2, TMOD1, TMOD2, TMOD3
Leiomodins: larger members of the tropomodulin (Tmod) gene family.
Conley CA, Fritz-Six KL, Almenar-Queralt A, Fowler VM.
Genomics 73(2):127-39. 2001
27TMOD1
Genomic organization of mouse and human erythrocyte tropomodulin genes encoding the pointed end capping protein for the actin filaments.
Chu X, Thompson D, Yee LJ, Sung LA.
Gene 256(1-2):271-81. 2000
28TMOD1
Gene assignment, expression, and homology of human tropomodulin.
Sung LA, et al.
Genomics 34 : 92-96. 1996