| 1 | TMEM106B
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| A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.
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| Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS.
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| Am J Hum Genet 101(5):643-663. doi: 10.1016/j.ajhg.2017.09.004. Epub 2017 Oct 19.
2017
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| 2 | SLC18A2, TMEM106B
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| Association analysis of polymorphisms in VMAT2 and TMEM106B genes for Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy.
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| Hu T, Chen Y, Ou R, Wei Q, Cao B, Zhao B, Wu Y, Song W, Chen X, Shang HF.
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| J Neurol Sci 377:65-71. doi: 10.1016/j.jns.2017.03.028. Epub 2017 Mar 21.
2017
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| 3 | HLD16, TMEM106B
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| A recurrent de novo mutation in TMEM106B causes hypomyelinating leukodystrophy.
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| Simons C, Dyment D, Bent SJ, Crawford J, D'Hooghe M, Kohlschütter A, Venkateswaran S, Helman G, Poll-The BT, Makowski CC, Ito Y, Kernohan K, Hartley T, Waisfisz Q, Taft RJ; Care4Rare Consortium, van der Knaap MS, Wolf NI.
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| Brain. Dec 1;140(12):3105-3111. doi: 10.1093/brain/awx314. 2017
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| 4 | TMEM106B
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| Transmembrane Protein 106B Gene (TMEM106B) Variability and Influence on Progranulin Plasma Levels in Patients with Alzheimer's Disease.
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| Serpente M, Fenoglio C, Clerici F, Bonsi R, Arosio B, Cioffi SM, Rotondo E, Franceschi M, Martinelli Boneschi F, Mari D, Mariani C, Scarpini E, Galimberti D.
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| J Alzheimers Dis 43(3):757-61. doi: 10.3233/JAD-141167.
2015
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| 5 | CHMP2B, TMEM106B
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| TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.
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| Jun MH, Han JH, Lee YK, Jang DJ, Kaang BK, Lee JA.
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| Mol Brain 8:85. doi: 10.1186/s13041-015-0177-z.
2015
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| 6 | TMEM106B
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| Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B.
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| Stagi M, Klein ZA, Gould TJ, Bewersdorf J, Strittmatter SM.
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| Mol Cell Neurosci 61:226-40. doi: 10.1016/j.mcn.2014.07.006. Epub 2014 Jul 24.
2014
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| 7 | SPPL2A, TMEM106B
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| Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
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| Brady OA, Zhou X, Hu F.
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| J Biol Chem 289(28):19670-80. doi: 10.1074/jbc.M113.515700. Epub 2014 May 28.
2014
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| 8 | TMEM106B
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| TMEM106B expression is reduced in Alzheimer's disease brains.
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| Satoh J, Kino Y, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K.
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| Alzheimers Res Ther 6(2):17. doi: 10.1186/alzrt247. eCollection 2014.
2014
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| 9 | TMEM106B
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| TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.
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| Nicholson AM, Finch NA, Wojtas A, Baker MC, Perkerson RB 3rd, Castanedes-Casey M, Rousseau L, Benussi L, Binetti G, Ghidoni R, Hsiung GY, Mackenzie IR, Finger E, Boeve BF, Ertekin-Taner N, Graff-Radford NR, Dickson DW, Rademakers R.
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| J Neurochem 126(6):781-91. doi: 10.1111/jnc.12329. Epub 2013 Jul 1.
2013
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| 10 | GRN, TMEM106B
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| The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.
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| Brady OA, Zheng Y, Murphy K, Huang M, Hu F.
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| Hum Mol Genet 22(4):685-95. doi: 10.1093/hmg/dds475. Epub 2012 Nov 6.
2013
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| 11 | TMEM106B
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| Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.
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| Lang CM, Fellerer K, Schwenk BM, Kuhn PH, Kremmer E, Edbauer D, Capell A, Haass C.
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| J Biol Chem 287(23):19355-65. doi: 10.1074/jbc.M112.365098. Epub 2012 Apr 17.
2012
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| 12 | TMEM106B
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| TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.
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| Finch N, Carrasquillo MM, Baker M, Rutherford NJ, Coppola G, Dejesus-Hernandez M, Crook R, Hunter T, Ghidoni R, Benussi L, Crook J, Finger E, Hantanpaa KJ, Karydas AM, Sengdy P, Gonzalez J, Seeley WW, Johnson N, Beach TG, Mesulam M, Forloni G, Kertesz A, Knopman DS, Uitti R, White CL 3rd, Caselli R, Lippa C, Bigio EH, Wszolek ZK, Binetti G, Mackenzie IR, Miller BL, Boeve BF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Geschwind DH, Rademakers R.
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| Neurology 76(5):467-74. Epub 2010 Dec 22.
2011
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| 13 | TMEM106B
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| Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis.
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| Vass R, Ashbridge E, Geser F, Hu WT, Grossman M, Clay-Falcone D, Elman L, McCluskey L, Lee VM, Van Deerlin VM, Trojanowski JQ, Chen-Plotkin AS.
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| Acta Neuropathol 121(3):373-80. doi: 10.1007/s00401-010-0782-y. Epub 2010 Nov 23.
2011
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| 14 | TMEM106B
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| Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
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| Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL 3rd, Ferrer I, Lladó A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, de Munain AL, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, DeCarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tuñón MT, Martínez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM.
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| Nat Genet 42(3):234-9. Epub 2010 Feb 14. 2010
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| 15 | ABL2, AKAP8, ANKRD13D, AP3D1, ARFGAP3, ARMCX6, ASUN, BAT2L, BCl2L13, BNIP3L, BPTF, BRD7, BZW1, BZW2, C12orf43, C19orf26, C1orf105, C2orf49, C6orf81, CA10, CAD, CARHSP1, CBX4, CCDC55, CCDC61, CCNK, CDC42BPB, CDC42EP3, CDC42EP4, CDS2, CENPN, CLK1, COPA, CSDA, CTPS2, DBN1, DCP1A, DECR2, DPF2, DPM1, EIF2AK1, EPB41L4A, EPN1, FAM91A1, FOSL2, FOXK1, GDF5OS, GFOD2, GIGYF2, GPATCH8, GTPBP1, HES7, HNRNPUL1, KIF1C, LPIN2, LRCH4, MAN2C1, MAST1, MED13, MED24, MED26, MINK1, MISP, MYO10, NKTR, OSBP, PAM, PCDH7, PEX14, PHF16, PHRF1, PLCB4, PLXNC1, POM121, POM121L2, PPHLN1, PRICKLE3, PRX, PUM2, RABGGTB, RBEL1, RIMS1, RIMS2, RPL14, RRP1B, RRP8, SAFB, SCAMP3, SCMH1, SCYL1, SENP6, SERBP1, SFRS13A, SFRS17A, SIPA1L1, SLC26A6, SLIRP, SLMAP, SNTA1, SORBS3, SPICE1, SSFA2, STAM, SUB1, TFIP11, TLN2, TMC6, TMEM104, TMEM106B, TMEM22, TOM1, UHRF1, UTP14A, WDR43, ZNF324, ZNF648
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| Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
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| Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.
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| Cell. 127(3):635-48. 2006
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