1 | ERN1, PARP16, RNF13, TMBIM6
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| IRE1α Signaling Pathways Involved in Mammalian Cell Fate Determination.
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| Wu J, He GT, Zhang WJ, Xu J, Huang QB.
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| Cell Physiol Biochem 38(3):847-58. doi: 10.1159/000443039. Epub 2016 Feb 25. Review.
2016
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2 | FAIM2, GHITM, GRINA, TMBIM1, TMBIM4, TMBIM6
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| The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
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| Lisak DA, Schacht T, Enders V, Habicht J, Kiviluoto S, Schneider J, Henke N, Bultynck G, Methner A.
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| Biochim Biophys Acta 1853(9):2104-14. doi: 10.1016/j.bbamcr.2015.03.002. Epub 2015 Mar 9.
2015
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3 | TMBIM6
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| The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
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| Lisak DA, Schacht T, Enders V, Habicht J, Kiviluoto S, Schneider J, Henke N, Bultynck G, Methner A.
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| Biochim Biophys Acta 1853(9):2104-14. doi: 10.1016/j.bbamcr.2015.03.002. Epub 2015 Mar 9.
2015
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4 | TMBIM6
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| Bax inhibitor-1 is likely a pH-sensitive calcium leak channel, not a H+/Ca2+ exchanger.
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| Bultynck G, Kiviluoto S, Methner A.
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| Sci Signal 7(343):pe22. doi: 10.1126/scisignal.2005764.
2014
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5 | TMBIM6
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| Bax inhibitor-1-mediated inhibition of mitochondrial Ca2+ intake regulates mitochondrial permeability transition pore opening and cell death.
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| Lee GH, Lee HY, Li B, Kim HR, Chae HJ.
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| Sci Rep 4:5194. doi: 10.1038/srep05194.
2014
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6 | TMBIM6
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| The characteristics of Bax inhibitor-1 and its related diseases.
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| Li B, Yadav RK, Jeong GS, Kim HR, Chae HJ.
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| Curr Mol Med 14(5):603-15. Review.
2014
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7 | TMBIM6
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| Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
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| Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G.
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| Cell Calcium 54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16.
2013
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8 | TMBIM6
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| The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
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| Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A.
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| J Biol Chem 287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28.
2012
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9 | TMBIM4, TMBIM6
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| Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family.
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| Carrara G, Saraiva N, Gubser C, Johnson BF, Smith GL.
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| J Biol Chem 287(19):15896-905. doi: 10.1074/jbc.M111.336149. Epub 2012 Mar 14.
2012
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10 | TMBIM6
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| Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy.
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| Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC.
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| Genes Dev 26(10):1041-54. doi: 10.1101/gad.184325.111.
2012
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11 | GRINA, TMBIM6
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| The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
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| Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A.
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| J Biol Chem 287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28.
2012
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12 | BFAR, TMBIM6
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| Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress.
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| Rong J, Chen L, Toth JI, Tcherpakov M, Petroski MD, Reed JC.
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| J Biol Chem 286(2):1453-63. Epub 2010 Nov 10.
2011
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13 | TMBIM6
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| Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor.
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| Ishikawa T, Watanabe N, Nagano M, Kawai-Yamada M, Lam E.
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| Cell Death Differ 18(8):1271-8. doi: 10.1038/cdd.2011.59. Epub 2011 May 20. Review.
2011
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14 | TMBIM6
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| Bax inhibitor-1 down-regulation in the progression of chronic liver diseases.
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| Kotsafti A, Farinati F, Cardin R, Burra P, Bortolami M.
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| BMC Gastroenterol 10:35.
2010
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15 | TMBIM6
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| Bax inhibitor 1 increases cell adhesion through actin polymerization: involvement of calcium and actin binding.
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| Lee GH, Ahn T, Kim DS, Park SJ, Lee YC, Yoo WH, Jung SJ, Yang JS, Kim S, Muhlrad A, Seo YR, Chae SW, Kim HR, Chae HJ.
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| Mol Cell Biol 30(7):1800-13. Epub 2010 Feb 1.
2010
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16 | FAIM2, GHITM, GRINA, TMBIM1, TMBIM4, TMBIM6
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| LFG: a candidate apoptosis regulatory gene family.
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| Hu L, Smith TF, Goldberger G.
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| Apoptosis 14(11):1255-65.PMID: 19784873 2009
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17 | TMBIM6
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| Bax inhibitor-1 overexpression reduces the suppressive effect of calcium mobilizing agent on adipogenesis.
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| Yu J, Kwon KB, Park JW, Chae HJ, Park BH.
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| Int J Biochem Cell Biol 41(8-9):1739-45. Epub 2009 Mar 28.
2009
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18 | GHITM, GRINA, TMBIM1, TMBIM4, TMBIM6
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| Comparative genomics and function analysis on BI1 family.
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| Zhou J, Zhu T, Hu C, Li H, Chen G, Xu G, Wang S, Zhou J, Ma D.
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| Comput Biol Chem 32(3):159-62. Epub 2008 Feb 8. 2008
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19 | TMBIM6
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| Bax Inhibitor-1 Is a pH-dependent regulator of Ca2+ channel activity in the endoplasmic reticulum.
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| Kim HR, Lee GH, Ha KC, Ahn T, Moon JY, Lee BJ, Cho SG, Kim S, Seo YR, Shin YJ, Chae SW, Reed JC, Chae HJ.
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| J Biol Chem 283(23):15946-55. Epub 2008 Mar 31.
2008
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20 | TMBIM6
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| Bax inhibitor-1 protects neurons from oxygen-glucose deprivation.
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| Dohm CP, Siedenberg S, Liman J, Esposito A, Wouters FS, Reed JC, Bähr M, Kermer P.
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| J Mol Neurosci 29(1):1-8.
2006
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21 | TMBIM6
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| The Bax inhibitor-1 gene is differentially regulated in adult testis and developing lung by two alternative TATA-less promoters.
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| Jean JC, et al.
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| Genomics 57(2):201-8. 1999
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22 | TMBIM6
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| Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast.
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| Xu Q, et al.
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| Mol Cell 1(3):337-46. 1998
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23 | TMBIM6
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| Identification of a novel conserved human gene, TEGT.
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| Walter L, et al.
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| Genomics 28 : 301-304. 1995
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