Citations for
1PHF6, TLX1, TLX3
PHF6 mutations in T-cell acute lymphoblastic leukemia.
Van Vlierberghe P, Palomero T, Khiabanian H, Van der Meulen J, Castillo M, Van Roy N, De Moerloose B, Philippé J, González-García S, Toribio ML, Taghon T, Zuurbier L, Cauwelier B, Harrison CJ, Schwab C, Pisecker M, Strehl S, Langerak AW, Gecz J, Sonneveld E, Pieters R, Paietta E, Rowe JM, Wiernik PH, Benoit Y, Soulier J, Poppe B, Yao X, Cordon-Cardo C, Meijerink J, Rabadan R, Speleman F, Ferrando A.
Nat Genet 42(4):338-42. Epub 2010 Mar 14. 2010
2TLX1
The TLX1 oncogene drives aneuploidy in T cell transformation.
De Keersmaecker K, Real PJ, Gatta GD, Palomero T, Sulis ML, Tosello V, Van Vlierberghe P, Barnes K, Castillo M, Sole X, Hadler M, Lenz J, Aplan PD, Kelliher M, Kee BL, Pandolfi PP, Kappes D, Gounari F, Petrie H, Van der Meulen J, Speleman F, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Soulier J, Avran D, Cavé H, Dastugue N, Raimondi S, Meijerink JP, Cordon-Cardo C, Califano A, Ferrando AA.
Nat Med 16(11):1321-7. Epub 2010 Oct 24.PMID: 20972433 2010
3NOTCH1, TLX1
TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells.
Riz I, Hawley TS, Luu TV, Lee NH, Hawley RG.
Mol Cancer 9:181.PMID: 20618946 2010
4MEIS1, MEIS2, TLX1
MEIS proteins as partners of the TLX1/HOX11 oncoprotein.
Milech N, Gottardo NG, Ford J, D'Souza D, Greene WK, Kees UR, Watt PM.
Leuk Res 34(3):358-63. Epub 2009 Jun 25.PMID: 19559479 2010
5TLE1, TLX1
Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors.
Riz I, Lee HJ, Baxter KK, Behnam R, Hawley TS, Hawley RG.
Biochem Biophys Res Commun 380(2):361-5. Epub 2009 Jan 23. 2009
6FHL1, TLX1
Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent.
Rice KL, Kees UR, Greene WK.
Biochem Biophys Res Commun 367(3):707-13. Epub 2007 Dec 10. 2008
7TLX1
Fetal Hox11 expression patterns predict defective target organs: a novel link between developmental biology and autoimmunity.
Lonyai A, Kodama S, Burger D, Faustman DL.
Immunol Cell Biol 86(4):301-9. Epub 2008 Feb 26.PMID: 18301381 2008
8TCL3, TD1, TLX1
A promoter with bidirectional activity is located between TLX1/HOX11 and a divergently transcribed novel human gene.
Greene WK, Sontani Y, Sharp MA, Dunn DS, Kees UR, Bellgard MI.
Gene 391(1-2):223-32. Epub 2007 Jan 20. 2007
9TLX1
Limb-girdle muscular dystrophy in the Netherlands: gene defect identified in half the families.
van der Kooi AJ, Frankhuizen WS, Barth PG, Howeler CJ, Padberg GW, Spaans F, Wintzen AR, Wokke JH, van Ommen GJ, de Visser M, Bakker E, Ginjaar HB.
Neurology 68(24):2125-8. 2007
10TLX1
TLX1/HOX11-induced hematopoietic differentiation blockade.
Riz I, Akimov SS, Eaker SS, Baxter KK, Lee HJ, Mariño-Ramírez L, Landsman D, Hawley TS, Hawley RG.
Oncogene 26(28):4115-23. Epub 2007 Jan 8.PMID: 17213805 2007
11TLX1
Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice.
Chen E, Lim MS, Rosic-Kablar S, Liu J, Jolicoeur P, Dubé ID, Hough MR.
Oncogene 25(18):2575-87.PMID: 16407851 2006
12TLX1
G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia.
Riz I, Hawley RG.
Oncogene 24(36):5561-75. 2005
13TLX1
Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia.
Ferrando AA, Neuberg DS, Dodge RK, Paietta E, Larson RA, Wiernik PH, Rowe JM, Caligiuri MA, Bloomfield CD, Look AT.
Lancet 363(9408):535-6. 2004
14TLX1, NR4A3
A microarray model system identifies potential new target genes of the proto-oncogene HOX11.
Hoffmann K, Dixon DN, Greene WK, Ford J, Taplin R, Kees UR.
Genes Chromosomes Cancer 41(4):309-20. 2004
15TLX1, TRD@
Molecular characterization of a complex chromosomal translocation breakpoint t(10;14) including the HOX11 oncogene locus.
Salvati PD, et al.
Leukemia 13(6):975-9. 1999
16TLX1, C10orf1
Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line.
Watt PM, Ranford PR, Kees UR.
Gene 234(1):169-76. 1999
17TLX1
Hox11 controls the genesis of the spleen.
Roberts CWM, et al.
Nature 368 : 747-749. 1994
18TLX1
The HOX-11 (TCL-3) homeobox proto-oncogene encodes a nuclear protein that undergoes cell cycle-dependent regulation.
Zhang N, et al.
Oncogene 8 : 3265-3270. 1993
19TLX1
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.
Dear TN, et al.
Proc Natl Acad Sci U S A 90 : 4431-4435. 1993
20TLX1
Genomic organization of the putative human homeobox proto-oncogene HOX-11 (TCL-3) and its endogenous expression in T cells.
Lu M, et al.
Oncogene 7 : 1325-1330. 1992
21TLX1, TRD@
S1 nuclease hypersensitive sites in an oligopurine/oligopyrimidine DNA from the t(10;14) breakpoint cluster region.
Lu M, et al.
Nucleic Acids Res 20 : 263-266. 1992
22TLX1
The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein.
Lu M, et al.
EMBO J 10 : 2905-2910. 1991
23TLX1
HOX-11, the first homeobox T cell oncogene is at the t(10;14) & t(7;10) junction.
Rabbitts TH, et al.
(HGM11) Cytogenet Cell Genet 58 : 1952. 1991
24TLX1
HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.
Kennedy MA, et al.
Proc Natl Acad Sci U S A 88 : 8900-8904. 1991
25TLX1
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia.
Hatano M, et al.
Science 253 : 79-82. 1991
26TCL3, TLX1
A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14).
Dube ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J, et al.
Blood 78(11):2996-3003. 1991
27TLX1
The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.
Zutter M, et al.
Proc Natl Acad Sci U S A 87 : 3161-3165. 1990
28TLX1
Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation.
Kagan J, et al.
Cancer Res 50 : 5240-5244. 1990
29TLX1
Cloning of the TCL3 oncogene.
DubŽ ID, et al.
(HGM10) Cytogenet Cell Genet 51 : 993. 1989
30TLX1
Sequencing of the breakpoint in the t(10;14) of T-cell neoplasia and identification of the putative TCL3 oncogene mRNA.
Lu M, et al.
Am J Hum Genet 45 : A27. 1989
31TLX1, TRD@
Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation.
Kagan J, et al.
Proc Natl Acad Sci U S A 86 : 4161-4165. 1989
32TLX1
Rearrangements of chromosome 10 in cutaneous T-cell lymphoma.
Warburton D, et al.
(HGM9) Cytogenet Cell Genet 46 : 711. 1987
33TLX1, TRA@
Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.
Kagan J, et al.
Proc Natl Acad Sci U S A 84 : 4543-4546. 1987
34TLX1
A new translocation, t(10;14)(q24;q11), in T cell neoplasia.
DubŽ ID, et al.
Blood 67 : 1181-1184. 1986