| 1 | ITGA2B, TLN1, WDR1
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| Wdr1-Dependent Actin Reorganization in Platelet Activation.
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| Dasgupta SK, Le A, Da Q, Cruz M, Rumbaut RE, Thiagarajan P.
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| PLoS One 11(9):e0162897. doi: 10.1371/journal.pone.0162897. eCollection 2016.
2016
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| 2 | TLN1, VCL
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| Vinculin controls talin engagement with the actomyosin machinery.
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| Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C.
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| Nat Commun 6:10038. doi: 10.1038/ncomms10038.
2015
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| 3 | RAP1A, TLN1
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| Talin1 and Rap1 are critical for osteoclast function.
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| Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley SJ, Critchley DR, Petrich BG, Morozov A, Ginsberg MH, Teitelbaum SL.
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| Mol Cell Biol 33(4):830-44. doi: 10.1128/MCB.00790-12. Epub 2012 Dec 10. 2013
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| 4 | CTSH, TLN1
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| Cathepsin H mediates the processing of talin and regulates migration of prostate cancer cells.
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| Jevnikar Z, Rojnik M, Jamnik P, Doljak B, Fonovic UP, Kos J.
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| J Biol Chem 288(4):2201-9. doi: 10.1074/jbc.M112.436394. Epub 2012 Nov 30.
2013
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| 5 | TLN1, TLN2
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| Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.
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| Manso AM, Li R, Monkley SJ, Cruz NM, Ong S, Lao DH, Koshman YE, Gu Y, Peterson KL, Chen J, Abel ED, Samarel AM, Critchley DR, Ross RS.
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| J Biol Chem 288(6):4252-64. doi: 10.1074/jbc.M112.427484. Epub 2012 Dec 24.
2013
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| 6 | CAPN2, TLN1
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| Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.
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| Bate N, Gingras AR, Bachir A, Horwitz R, Ye F, Patel B, Goult BT, Critchley DR.
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| PLoS One 7(4):e34461. doi: 10.1371/journal.pone.0034461. Epub 2012 Apr 4.
2012
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| 7 | TLN1
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| Subcellular localization of talin is regulated by inter-domain interactions.
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| Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH.
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| J Biol Chem 287(17):13799-812. doi: 10.1074/jbc.M112.341214. Epub 2012 Feb 18.
2012
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| 8 | PTK2, TLN1
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| FAK promotes recruitment of talin to nascent adhesions to control cell motility.
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| Lawson C, Lim ST, Uryu S, Chen XL, Calderwood DA, Schlaepfer DD.
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| J Cell Biol 196(2):223-32. doi: 10.1083/jcb.201108078. Erratum in: J Cell Biol. 2012 Feb 6;196(3):387.
2012
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| 9 | TLN1, TLN2
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| New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.
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| Praekelt U, Kopp PM, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso AM, Ross RS, Conti F, Zhang MZ, Harris RC, Zent R, Critchley DR, Monkley SJ.
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| Eur J Cell Biol 91(3):180-91. doi: 10.1016/j.ejcb.2011.12.003. Epub 2012 Feb 3.
2012
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| 10 | TLN1
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| Endothelial cell talin1 is essential for embryonic angiogenesis.
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| Monkley SJ, Kostourou V, Spence L, Petrich B, Coleman S, Ginsberg MH, Pritchard CA, Critchley DR.
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| Dev Biol 349(2):494-502. Epub 2010 Nov 26.
2011
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| 11 | ITGB1, TLN1
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| Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.
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| Liu J, He X, Qi Y, Tian X, Monkley SJ, Critchley DR, Corbett SA, Lowry SF, Graham AM, Li S.
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| Mol Cell Biol 31(16):3366-77. Epub 2011 Jun 13.
2011
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| 12 | TLN1
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| The C terminus of talin links integrins to cell cycle progression.
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| Wang P, Ballestrem C, Streuli CH.
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| J Cell Biol 195(3):499-513. doi: 10.1083/jcb.201104128.
2011
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| 13 | TLN1, TLNRD1
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| Central region of talin has a unique fold that binds vinculin and actin.
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| Gingras AR, Bate N, Goult BT, Patel B, Kopp PM, Emsley J, Barsukov IL, Roberts GC, Critchley DR.
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| J Biol Chem 285(38):29577-87. Epub 2010 Jul 7. 2010
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| 14 | TLN1
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| Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen.
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| Manevich-Mendelson E, Grabovsky V, Feigelson SW, Cinamon G, Gore Y, Goverse G, Monkley SJ, Margalit R, Melamed D, Mebius RE, Critchley DR, Shachar I, Alon R.
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| Blood 116(26):5907-18. Epub 2010 Oct 5.
2010
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| 15 | TLN1
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| Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.
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| Sakamoto S, McCann RO, Dhir R, Kyprianou N.
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| Cancer Res 70(5):1885-95. doi: 10.1158/0008-5472.CAN-09-2833. Epub 2010 Feb 16.
2010
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| 16 | TLN1
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| Functional and structural characterization of the talin F0F1 domain.
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| Domadia PN, Li YF, Bhunia A, Mohanram H, Tan SM, Bhattacharjya S.
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| Biochem Biophys Res Commun 391(1):159-65. doi: 10.1016/j.bbrc.2009.11.024. Epub 2009 Nov 10.
2010
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| 17 | TLN1, VCL
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| Dystrophin-glycoprotein complex and vinculin-talin-integrin system in human adult cardiac muscle.
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| Anastasi G, Cutroneo G, Gaeta R, Di Mauro D, Arco A, Consolo A, Santoro G, Trimarchi F, Favaloro A.
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| Int J Mol Med 23(2):149-59.PMID: 19148538 2009
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| 18 | TLN1, TLN2
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| Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.
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| Conti FJ, Monkley SJ, Wood MR, Critchley DR, Müller U.
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| Development 136(21):3597-606. doi: 10.1242/dev.035857. Epub 2009 Sep 30.
2009
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| 19 | TLN1
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| The structure of the C-terminal actin-binding domain of talin.
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| Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR.
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| EMBO J 27(2):458-69. Epub 2007 Dec 20. 2008
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| 20 | TLN1
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| An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.
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| Oxley CL, Anthis NJ, Lowe ED, Vakonakis I, Campbell ID, Wegener KL.
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| J Biol Chem 283(9):5420-6. Epub 2007 Dec 21.PMID: 18156175 2008
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| 21 | TLN1, TLN2
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| Talin2 is induced during striated muscle differentiation and is targeted to stable adhesion complexes in mature muscle.
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| Senetar MA, Moncman CL, McCann RO.
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| Cell Motil Cytoskeleton 64(3):157-73.
2007
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| 22 | TLN1, VCL
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| Vinculin controls focal adhesion formation by direct interactions with talin and actin.
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| Humphries JD, Wang P, Streuli C, Geiger B, Humphries MJ, Ballestrem C.
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| J Cell Biol 179(5):1043-57. 2007
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| 23 | TLN1
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| A C-terminal dimerization motif is required for focal adhesion targeting of Talin1 and the interaction of the Talin1 I/LWEQ module with F-actin.
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| Smith SJ, McCann RO.
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| Biochemistry 46(38):10886-98. Epub 2007 Aug 28.PMID: 17722883 2007
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| 24 | TLN1, TLN2
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| Gene duplication and functional divergence during evolution of the cytoskeletal linker protein talin.
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| Senetar MA, McCann RO.
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| Gene 362:141-52. Epub 2005 Oct 10. 2005
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| 25 | TLN1, TLN2
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| Characterization of an actin-binding site within the talin FERM domain.
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| Lee HS, Bellin RM, Walker DL, Patel B, Powers P, Liu H, Garcia-Alvarez B, de Pereda JM, Liddington RC, Volkmann N, Hanein D, Critchley DR, Robson RM.
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| J Mol Biol 343(3):771-84. 2004
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| 26 | TLN1, TLN2
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| Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin.
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| Di Paolo G, Pellegrini L, Letinic K, Cestra G, Zoncu R, Voronov S, Chang S, Guo J, Wenk MR, De Camilli P.
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| Nature 420(6911):85-9. 2002
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| 27 | TLN1
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| Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.
|
| Ben-Yosef T, Francomano CA.
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| Genomics 62(2):316-9 1999
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| 28 | TLN1
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| Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix.
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| Bass MD, Smith BJ, Prigent SA, Critchley DR.
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| Biochem J 341 ( Pt 2):257-63 1999
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| 29 | ICAM1, ICAM3, ICAM4, TLN1
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| Mapping of the ICAM-5 (telencephalin) gene, a neuronal member of the ICAM family, to a location between ICAM-1 and ICAM-3 on human chromosome 19p13.2.
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| Kilgannon P, et al.
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| Genomics 54 : 328-330. 1998
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| 30 | ITGAL, ITGB2, TLN1
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| cDNA cloning and chromosomal localization of the human telencephalin and its distinctive interaction with lymphocyte function-associated antigen-1.
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| Mizuno T, et al.
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| J Biol Chem 272 : 1156-1163. 1997
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| 31 | TLN1
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| Construction of a radiation hybrid map of chromosome 9p.
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| Bouzyk M, et al.
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| Genomics 34 : 187-192. 1996
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| 32 | TLN1
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| Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p.
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| Gilmore AP, Ohanian V, Spurr NK, Critchley DR.
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| Hum Genet 96(2):221-4. 1995
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| 33 | TLN1
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| The cytoskeletal protein talin contains at least two distinct vinculin binding domains.
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| Gilmore AP, Wood C, Ohanian V, Jackson P, Patel B, Rees DJ, Hynes RO, Critchley DR.
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| J Cell Biol 122(2):337-47 1993
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| 34 | EPB41, MSN, NF2, PTPN13, PTPN3, RDX, TLN1, EZR
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| A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.
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| Sato N, et al.
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| J Cell Sci 103 : 131-143. 1992
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| 35 | TLN1
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| Sequence and domain structure of talin.
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| Rees DJG, et al.
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| Nature 347 : 685-689. 1990
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| 36 | TLN1
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| Functional studies of the domains of talin.
|
| Nuckolls GH, Turner CE, Burridge K.
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| J Cell Biol 110(5):1635-44 1990
|