1 | FOXG1, TLE1
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| Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.
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| Dastidar SG, Narayanan S, Stifani S, D'Mello SR.
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| J Biol Chem 287(18):14749-59. doi: 10.1074/jbc.M111.328336. Epub 2012 Feb 21.
2012
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2 | TLE1
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| TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells.
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| Brunquell C, Biliran H, Jennings S, Ireland SK, Chen R, Ruoslahti E.
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| Mol Cancer Res 10(11):1482-95. doi: 10.1158/1541-7786.MCR-12-0144. Epub 2012 Sep 4.
2012
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3 | TLE1
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| The role of TLE1 in synovial sarcoma.
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| Seo SW, Lee H, Lee HI, Kim HS.
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| J Orthop Res 29(7):1131-6. doi: 10.1002/jor.21318. Epub 2011 Feb 11.
2011
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4 | RUNX2, TLE1, UBTF
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| Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes.
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| Ali SA, Zaidi SK, Dobson JR, Shakoori AR, Lian JB, Stein JL, van Wijnen AJ, Stein GS.
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| Proc Natl Acad Sci U S A 107(9):4165-9. Epub 2010 Feb 16. 2010
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5 | HESX1, PROP1, TLE1, TLE3
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| Corepressors TLE1 and TLE3 interact with HESX1 and PROP1.
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| Carvalho LR, Brinkmeier ML, Castinetti F, Ellsworth BS, Camper SA.
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| Mol Endocrinol 24(4):754-65. Epub 2010 Feb 24.PMID: 20181723 2010
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6 | HHEX, TLE1
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| The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors.
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| Desjobert C, Noy P, Swingler T, Williams H, Gaston K, Jayaraman PS.
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| Biochem J 417(1):121-32.
2009
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7 | TLE1, TLX1
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| Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors.
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| Riz I, Lee HJ, Baxter KK, Behnam R, Hawley TS, Hawley RG.
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| Biochem Biophys Res Commun 380(2):361-5. Epub 2009 Jan 23.
2009
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8 | TLE1
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| Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies.
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| Fraga MF, Berdasco M, Ballestar E, Ropero S, Lopez-Nieva P, Lopez-Serra L, Martín-Subero JI, Calasanz MJ, Lopez de Silanes I, Setien F, Casado S, Fernandez AF, Siebert R, Stifani S, Esteller M.
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| Cancer Res 68(11):4116-22.
2008
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9 | TLE1, TLE4
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| Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.
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| Dayyani F, Wang J, Yeh JR, Ahn EY, Tobey E, Zhang DE, Bernstein ID, Peterson RT, Sweetser DA.
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| Blood 111(8):4338-47. Epub 2008 Feb 7.
2008
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10 | TLE1
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| TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies.
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| Terry J, Saito T, Subramanian S, Ruttan C, Antonescu CR, Goldblum JR, Downs-Kelly E, Corless CL, Rubin BP, van de Rijn M, Ladanyi M, Nielsen TO.
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| Am J Surg Pathol 31(2):240-6.
2007
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11 | TLE1
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| Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation.
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| Daniels DL, Weis WI.
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| Nat Struct Mol Biol 12(4):364-71. Epub 2005 Mar 13.
2005
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12 | AES, TLE1, TLE2, TLE3, TLE4
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| The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.
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| Rave-Harel N, Miller NL, Givens ML, Mellon PL.
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| J Biol Chem 280(35):30975-83. Epub 2005 Jul 7.
2005
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13 | ESRRG, TLE1, PNRC2
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| Identification of PNRC2 and TLE1 as activation function-1 cofactors of the orphan nuclear receptor ERRgamma.
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| Hentschke M, Borgmeyer U.
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| Biochem Biophys Res Commun 312(4):975-82. 2003
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14 | RUNX1, TLE1
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| TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation.
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| Imai Y, et al.
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| Biochem Biophys Res Commun 252 : 582-589. 1998
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15 | TLE1, TLE1, TLE2, TLE3
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| Epithelial expression and chromosomal location of human TLE genes : implications for Notch signaling and neoplasia.
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| Liu Y, et al.
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| Genomics 31 : 58-64. 1996
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16 | AES,TLE1,TLE3,TLE4
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| Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to drosophila enhancer of split groucho protein.
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| Miyasaka H, et al.
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| Eur J Biochem 216 : 343-352. 1993
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17 | AES, TLE1, TLE2, TLE3, TLE4
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| Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.
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| Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S.
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| Nat Genet 2(2):119-27. 1992
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