| 1 | SNX27, TJP2
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| Sorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junction.
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| Zimmerman SP, Hueschen CL, Malide D, Milgram SL, Playford MP.
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| Biochem J 455(1):95-106. doi: 10.1042/BJ20121755.
2013
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| 2 | TJP2
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| Zona occludens-2 protects against podocyte dysfunction induced by ADR in mice.
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| Bautista-García P, Reyes JL, Martín D, Namorado MC, Chavez-Munguía B, Soria-Castro E, Huber O, González-Mariscal L.
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| Am J Physiol Renal Physiol 304(1):F77-87. doi: 10.1152/ajprenal.00089.2012. Epub 2012 Oct 3.
2013
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| 3 | LASP1, TJP2
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| Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.
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| Mihlan S, Reiß C, Thalheimer P, Herterich S, Gaetzner S, Kremerskothen J, Pavenstädt HJ, Lewandrowski U, Sickmann A, Butt E.
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| Oncogene 32(16):2107-13. doi: 10.1038/onc.2012.216. Epub 2012 Jun 4.
2013
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| 4 | F11R, RAP2C, RAPGEF2, TJP2
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| JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.
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| Monteiro AC, Sumagin R, Rankin CR, Leoni G, Mina MJ, Reiter DM, Stehle T, Dermody TS, Schaefer SA, Hall RA, Nusrat A, Parkos CA.
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| Mol Biol Cell 24(18):2849-60. doi: 10.1091/mbc.E13-06-0298. Epub 2013 Jul 24.
2013
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| 5 | TJP1, TJP2
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| Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia.
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| Fanning AS, Van Itallie CM, Anderson JM.
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| Mol Biol Cell 23(4):577-90. doi: 10.1091/mbc.E11-09-0791. Epub 2011 Dec 21.
2012
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| 6 | AMOTL1, TJP2, YAP1
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| Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP.
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| Oka T, Schmitt AP, Sudol M.
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| Oncogene 31(1):128-34. doi: 10.1038/onc.2011.216. Epub 2011 Jun 20.
2012
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| 7 | TJP2
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| ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosis.
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| Gonzalez-Mariscal L, Bautista P, Lechuga S, Quiros M.
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| Ann N Y Acad Sci 1257:133-41. doi: 10.1111/j.1749-6632.2012.06537.x. Review.
2012
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| 8 | JAK1, TJP2
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| The tight junction protein ZO-2 and Janus kinase 1 mediate intercellular communications in vascular smooth muscle cells.
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| Tkachuk N, Tkachuk S, Patecki M, Kusch A, Korenbaum E, Haller H, Dumler I.
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| Biochem Biophys Res Commun 410(3):531-6. Epub 2011 Jun 7.
2011
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| 9 | DFNA51, GSK3B, TJP2
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| Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51.
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| Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB.
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| Am J Hum Genet 87(1):101-9. Epub 2010 Jun 17.PMID: 20602916 2010
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| 10 | TAZ, TJP1, TJP2
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| TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner.
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| Remue E, Meerschaert K, Oka T, Boucherie C, Vandekerckhove J, Sudol M, Gettemans J.
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| FEBS Lett 584(19):4175-80. Epub 2010 Sep 18.
2010
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| 11 | TJP2, YAP1
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| Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling.
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| Oka T, Remue E, Meerschaert K, Vanloo B, Boucherie C, Gfeller D, Bader GD, Sidhu SS, Vandekerckhove J, Gettemans J, Sudol M.
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| Biochem J 432(3):461-72.
2010
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| 12 | ANGPT1, TJP, TJP2
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| Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2.
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| Lee SW, Kim WJ, Jun HO, Choi YK, Kim KW.
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| Int J Mol Med 23(2):279-84. 2009
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| 13 | TJP2
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| Structure of the second PDZ domain from human zonula occludens 2.
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| Chen H, Tong S, Li X, Wu J, Zhu Z, Niu L, Teng M.
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| Acta Crystallogr Sect F Struct Biol Cryst Commun 65(Pt 4):327-30. Epub 2009 Mar 25.
2009
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| 14 | GJD2, TJP2
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| Direct association of connexin36 with zonula occludens-2 and zonula occludens-3.
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| Li X, Lu S, Nagy JI.
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| Neurochem Int 54(5-6):393-402.
2009
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| 15 | TJP1, TJP2, TJP3
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| Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.
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| Tsukita S, Katsuno T, Yamazaki Y, Umeda K, Tamura A, Tsukita S.
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| Ann N Y Acad Sci 1165:44-52.
2009
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| 16 | TJP1, TJP2
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| The second PDZ domain of zonula occludens-1 is dispensable for targeting to connexin 43 gap junctions.
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| Hunter AW, Gourdie RG.
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| Cell Commun Adhes 15(1):55-63.
2008
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| 17 | TJP2
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| Nuclear Zonula occludens-2 alters gene expression and junctional stability in epithelial and endothelial cells.
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| Traweger A, Lehner C, Farkas A, Krizbai IA, Tempfer H, Klement E, Guenther B, Bauer HC, Bauer H.
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| Differentiation 76(1):99-106. Epub 2007 Oct 31.PMID: 17973926 2008
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| 18 | TJP1, TJP2, TJP3
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| Domain swapping within PDZ2 is responsible for dimerization of ZO proteins.
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| Fanning AS, Lye MF, Anderson JM, Lavie A.
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| J Biol Chem 282(52):37710-6. Epub 2007 Oct 9.
2007
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| 19 | OCLN, TJP1, TJP2, TJP3
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| Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface.
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| Li Y, Fanning AS, Anderson JM, Lavie A.
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| J Mol Biol 352(1):151-64. 2005
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| 20 | BAAT, FHCA1, TJP2
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| Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT.
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| Carlton VE, Harris BZ, Puffenberger EG, Batta AK, Knisely AS, Robinson DL, Strauss KA, Shneider BL, Lim WA, Salen G, Morton DH, Bull LN.
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| Nat Genet 34(1):91-6. 2003
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| 21 | TJP2
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| Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues.
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| Chlenski A, Ketels KV, Korovaitseva GI, Talamonti MS, Oyasu R, Scarpelli DG.
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| Biochim Biophys Acta 1493(3):319-24. 2000
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| 22 | TJP2
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| Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin.
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| Itoh M, et al.
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| J Biol Chem 274(9):5981-6. 1999
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| 23 | CLDN1, TJP1, TJP2, TJP3
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| Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.
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| Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S.
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| J Cell Biol 147(6):1351-63. 1999
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| 24 | TJP1, TJP2
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| The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton.
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| Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM.
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| J Biol Chem 273 : 29745-29753. 1998
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| 25 | TJP1, TJP2, TJP3
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| ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin.
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| Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR.
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| J Cell Biol 141(1):199-208. 1998
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| 26 | TJP2
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| Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein.
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| Jesaitis LA, et al.
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| J Cell Biol 124 : 949-961. 1994
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| 27 | TJP1, TJP2
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| The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1 , a tight junction-associated protein in epithelial cells : cDNA cloning and immunoelectron microscopy.
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| Itoh M, et al.
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| J Cell Biol 12 : 491-502. 1993
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