1 | TIMP2
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| Matrisome-Associated Gene Expression Patterns Correlating with TIMP2 in Cancer.
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| Peeney D, Fan Y, Nguyen T, Meerzaman D, Stetler-Stevenson WG
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| Sci Rep. Dec 27;9(1):20142. doi: 10.1038/s41598-019-56632-3. 2019
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2 | MMP9, TIMP2
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| TIMP-2 inhibits metastasis and predicts prognosis of colorectal cancer via regulating MMP-9
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| Wang W, Li D, Xiang L, Lv M, Tao L, Ni T, Deng J, Gu X, Masatara S, Liu Y, Zhou Y.
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| Cell Adh Migr. Dec;13(1):273-284. doi: 10.1080/19336918.2019.1639303. 2019
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3 | EZH2, TIMP2
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| EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion. 2017 . PMID:
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| Yi X, Guo J, Guo J, Sun S, Yang P, Wang J, Li Y, Xie L, Cai J, Wang Z.
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| Sci Rep. Jun 15;7(1):3568. doi: 10.1038/s41598-017-03362-z 2017
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4 | TIMP2, TIMP3
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| Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction.
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| Fan D, Takawale A, Basu R, Patel V, Lee J, Kandalam V, Wang X, Oudit GY, Kassiri Z.
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| Cardiovasc Res 103(2):268-80. doi: 10.1093/cvr/cvu072. Epub 2014 Apr 1.
2014
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5 | TIMP1, TIMP2
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| miR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling.
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| Li SH, Guo J, Wu J, Sun Z, Han M, Wan Shan S, Deng Z, Yang BB, Weisel RD, Li RK.
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| FASEB J ASEB J. 2013 Jul 1. [Epub ahead of print]
2013
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6 | MMP14, MMP2, TIMP2
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| MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells
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| Lee H, Chang KW, Yang HY, Lin PW, Chen SU, Huang YL.
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| Biochem Biophys Res Commun. Jul 26;437(2):232-8. doi: 10.1016/j.bbrc.2013.06.046. Epub 2013 Jun 21. 2013
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7 | MMP9, TIMP2, VIM
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| Immunohistochemical expression of MMP-9, TIMP-2, E-cadherin and vimentin in ameloblastomas and their implication in the local aggressive behavior of these tumors.
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| Florescu A, Mărgăritescu C, Simionescu CE, Stepan A.
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| Rom J Morphol Embryol 53(4):975-84.
2012
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8 | MMP10, TIMP1, TIMP2
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| Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.
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| Batra J, Robinson J, Soares AS, Fields AP, Radisky DC, Radisky ES.
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| J Biol Chem 287(19):15935-46. doi: 10.1074/jbc.M112.341156. Epub 2012 Mar 16.
2012
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9 | MMP14, MMP2, TIMP2
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| Is matrix metalloproteinase required in postnatal testicular tubules for germ cell maturation?
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| Li R, Zhang JG, Churchill J, Sourial M, Southwell BR, Hutson JM.
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| J Pediatr Surg 47(9):1724-9. doi: 10.1016/j.jpedsurg.2012.03.062.
2012
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10 | ADAM12? ADAM17, TIMP2
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| Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
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| Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.
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| Biochem J 430(1):79-86. 2010
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11 | ADAM12, ADAM17, TIMP2
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| Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
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| Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.
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| Biochem J 430(1):79-86.
2010
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12 | MMP9, TIMP2
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| Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.
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| Vatansever S, Gelisgen R, Uzun H, Yurt S, Kosar F.
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| Clin Invest Med 32(4):E293-300.PMID: 19640333 2009
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13 | TIMP2, TIMP3
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| Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival.
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| Peterson NB, Beeghly-Fadiel A, Gao YT, Long J, Cai Q, Shu XO, Zheng W.
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| Int J Cancer 125(4):844-50.PMID: 19431211 2009
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14 | MMP14, TIMP2
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| Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.
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| D'Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, Rozanov DV, Remacle AG, Oh ES, Shiryaev SA, Strongin AY, Pintucci G, Mignatti P.
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| J Biol Chem 283(1):87-99. Epub 2007 Nov 8.PMID: 17991754 2008
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15 | TIMP3, TIMP1, TIMP2, TIMP4
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| Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1.
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| Lee MH, Atkinson S, Murphy G.
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| J Biol Chem 282(9):6887-98. Epub 2007 Jan 3. 2007
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16 | ADAMTS16, ADAMTS17, MMP28, TIMP2
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| Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.
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| Davidson RK, Waters JG, Kevorkian L, Darrah C, Cooper A, Donell ST, Clark IM.
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| Arthritis Res Ther 8(4):R124.PMID: 16859525 2006
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17 | TIMP2
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| Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer.
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| Ivanova T, Vinokurova S, Petrenko A, Eshilev E, Solovyova N, Kisseljov F, Kisseljova N.
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| Int J Cancer 108(6):882-6. 2004
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18 | MMP2, TIMP2
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| Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
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| Sogawa K, Kondo K, Fujino H, Takahashi Y, Miyoshi T, Sakiyama S, Mukai K, Monden Y.
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| Cancer 98(9):1822-9. 2003
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19 | MMP2, MMP14, TIMP2
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| Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenation.
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| Ben-Yosef Y, Lahat N, Shapiro S, Bitterman H, Miller A.
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| Circ Res 90(7):784-91. 2002
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20 | MMP2, TIMP2
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| Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue.
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| Still K, Robson CN, Autzen P, Robinson MC, Hamdy FC.
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| Prostate 42(1):18-25. 2000
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21 | MMP14, MMP2, TIMP2
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| Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.
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| Hernandez-Barrantes S, Toth M, Bernardo MM, Yurkova M, Gervasi DC, Raz Y, Sang QA, Fridman R.
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| J Biol Chem 275(16):12080-9. 2000
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22 | TIMP2
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| TIMP-2 is required for efficient activation of proMMP-2 in vivo.
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| Wang Z, Juttermann R, Soloway PD.
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| J Biol Chem 275(34):26411-5. 2000
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23 | SYN1, SYN2, SYN3, SYN4, TIMP1, TIMP2, TIMP3, TIMP4
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| Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human.
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| Pohar N, et al.
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| Genomics 57(2):293-6. 1999
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24 | TIMP1, TIMP2
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| Expression of matrix metalloproteinases (MMP-2 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in acute myelogenous leukaemia blasts: comparison with normal bone marrow cells.
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| Janowska-Wieczorek A, et al.
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| Br J Haematol 105(2):402-11. 1999
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25 | TIMP1, TIMP2, TIMP3, TIMP4
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| Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.
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| Gomez DE, et al.
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| Eur J Cell Biol 74(2):111-22. Review. 1997
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26 | TIMP2
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| Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene.
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| Hammani K, et al.
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| J Biol Chem 271 : 25498-25505. 1996
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27 | TIMP2
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| Taql polymorphism of the human tissue inhibitor of metallo-proteinases-2 (Timp2) gene.
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| Jares P, et al.
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| Hum Mol Genet 3 : 218. 1994
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28 | TIMP2
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| The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25.
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| Clerck Y de, et al.
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| Genomics 14 : 782-784. 1992
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