Citations for
1TIMP2
Matrisome-Associated Gene Expression Patterns Correlating with TIMP2 in Cancer.
Peeney D, Fan Y, Nguyen T, Meerzaman D, Stetler-Stevenson WG
Sci Rep. Dec 27;9(1):20142. doi: 10.1038/s41598-019-56632-3. 2019
2MMP9, TIMP2
TIMP-2 inhibits metastasis and predicts prognosis of colorectal cancer via regulating MMP-9
Wang W, Li D, Xiang L, Lv M, Tao L, Ni T, Deng J, Gu X, Masatara S, Liu Y, Zhou Y.
Cell Adh Migr. Dec;13(1):273-284. doi: 10.1080/19336918.2019.1639303. 2019
3EZH2, TIMP2
EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion. 2017 . PMID:
Yi X, Guo J, Guo J, Sun S, Yang P, Wang J, Li Y, Xie L, Cai J, Wang Z.
Sci Rep. Jun 15;7(1):3568. doi: 10.1038/s41598-017-03362-z 2017
4TIMP2, TIMP3
Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction.
Fan D, Takawale A, Basu R, Patel V, Lee J, Kandalam V, Wang X, Oudit GY, Kassiri Z.
Cardiovasc Res 103(2):268-80. doi: 10.1093/cvr/cvu072. Epub 2014 Apr 1. 2014
5TIMP1, TIMP2
miR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling.
Li SH, Guo J, Wu J, Sun Z, Han M, Wan Shan S, Deng Z, Yang BB, Weisel RD, Li RK.
FASEB J ASEB J. 2013 Jul 1. [Epub ahead of print] 2013
6MMP14, MMP2, TIMP2
MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells
Lee H, Chang KW, Yang HY, Lin PW, Chen SU, Huang YL.
Biochem Biophys Res Commun. Jul 26;437(2):232-8. doi: 10.1016/j.bbrc.2013.06.046. Epub 2013 Jun 21. 2013
7MMP9, TIMP2, VIM
Immunohistochemical expression of MMP-9, TIMP-2, E-cadherin and vimentin in ameloblastomas and their implication in the local aggressive behavior of these tumors.
Florescu A, Mărgăritescu C, Simionescu CE, Stepan A.
Rom J Morphol Embryol 53(4):975-84. 2012
8MMP10, TIMP1, TIMP2
Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.
Batra J, Robinson J, Soares AS, Fields AP, Radisky DC, Radisky ES.
J Biol Chem 287(19):15935-46. doi: 10.1074/jbc.M112.341156. Epub 2012 Mar 16. 2012
9MMP14, MMP2, TIMP2
Is matrix metalloproteinase required in postnatal testicular tubules for germ cell maturation?
Li R, Zhang JG, Churchill J, Sourial M, Southwell BR, Hutson JM.
J Pediatr Surg 47(9):1724-9. doi: 10.1016/j.jpedsurg.2012.03.062. 2012
10ADAM12? ADAM17, TIMP2
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.
Biochem J 430(1):79-86. 2010
11ADAM12, ADAM17, TIMP2
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.
Biochem J 430(1):79-86. 2010
12MMP9, TIMP2
Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.
Vatansever S, Gelisgen R, Uzun H, Yurt S, Kosar F.
Clin Invest Med 32(4):E293-300.PMID: 19640333 2009
13TIMP2, TIMP3
Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival.
Peterson NB, Beeghly-Fadiel A, Gao YT, Long J, Cai Q, Shu XO, Zheng W.
Int J Cancer 125(4):844-50.PMID: 19431211 2009
14MMP14, TIMP2
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.
D'Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, Rozanov DV, Remacle AG, Oh ES, Shiryaev SA, Strongin AY, Pintucci G, Mignatti P.
J Biol Chem 283(1):87-99. Epub 2007 Nov 8.PMID: 17991754 2008
15TIMP3, TIMP1, TIMP2, TIMP4
Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1.
Lee MH, Atkinson S, Murphy G.
J Biol Chem 282(9):6887-98. Epub 2007 Jan 3. 2007
16ADAMTS16, ADAMTS17, MMP28, TIMP2
Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.
Davidson RK, Waters JG, Kevorkian L, Darrah C, Cooper A, Donell ST, Clark IM.
Arthritis Res Ther 8(4):R124.PMID: 16859525 2006
17TIMP2
Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer.
Ivanova T, Vinokurova S, Petrenko A, Eshilev E, Solovyova N, Kisseljov F, Kisseljova N.
Int J Cancer 108(6):882-6. 2004
18MMP2, TIMP2
Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
Sogawa K, Kondo K, Fujino H, Takahashi Y, Miyoshi T, Sakiyama S, Mukai K, Monden Y.
Cancer 98(9):1822-9. 2003
19MMP2, MMP14, TIMP2
Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenation.
Ben-Yosef Y, Lahat N, Shapiro S, Bitterman H, Miller A.
Circ Res 90(7):784-91. 2002
20MMP2, TIMP2
Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue.
Still K, Robson CN, Autzen P, Robinson MC, Hamdy FC.
Prostate 42(1):18-25. 2000
21MMP14, MMP2, TIMP2
Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.
Hernandez-Barrantes S, Toth M, Bernardo MM, Yurkova M, Gervasi DC, Raz Y, Sang QA, Fridman R.
J Biol Chem 275(16):12080-9. 2000
22TIMP2
TIMP-2 is required for efficient activation of proMMP-2 in vivo.
Wang Z, Juttermann R, Soloway PD.
J Biol Chem 275(34):26411-5. 2000
23SYN1, SYN2, SYN3, SYN4, TIMP1, TIMP2, TIMP3, TIMP4
Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human.
Pohar N, et al.
Genomics 57(2):293-6. 1999
24TIMP1, TIMP2
Expression of matrix metalloproteinases (MMP-2 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in acute myelogenous leukaemia blasts: comparison with normal bone marrow cells.
Janowska-Wieczorek A, et al.
Br J Haematol 105(2):402-11. 1999
25TIMP1, TIMP2, TIMP3, TIMP4
Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.
Gomez DE, et al.
Eur J Cell Biol 74(2):111-22. Review. 1997
26TIMP2
Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene.
Hammani K, et al.
J Biol Chem 271 : 25498-25505. 1996
27TIMP2
Taql polymorphism of the human tissue inhibitor of metallo-proteinases-2 (Timp2) gene.
Jares P, et al.
Hum Mol Genet 3 : 218. 1994
28TIMP2
The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25.
Clerck Y de, et al.
Genomics 14 : 782-784. 1992