| 1 | CCND1, CLDN16, CPE, LRP1B, MAGI3, MAPK6, MATN2, MPPED2, PFKFB2, PTPRE, PYGL, SEMA3D, SERGEF, SLC4A4, TIMP1
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| robust biomarker of differential correlations improves the diagnosis of cytologically indeterminate thyroid cancers
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| Gomez-Rueda H, Palacios-Corona R, Gutiérrez-Hermosillo H, Trevino V. A
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| Int J Mol Med. May;37(5):1355-62. doi: 10.3892/ijmm.2016.2534. Epub 2016 Mar 2016
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| 2 | KLK1, TIMP1
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| Synergistic effect of a tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 co‑expression vector on the proliferation of rat vascular smooth muscle cells.
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| Zhu P, Yu H, Huang S, Xiang H, Li F, Zheng W.
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| Mol Med Rep 12(4):5671-8. doi: 10.3892/mmr.2015.4198. Epub 2015 Aug 7.
2015
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| 3 | TIMP1, TIMP2
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| miR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling.
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| Li SH, Guo J, Wu J, Sun Z, Han M, Wan Shan S, Deng Z, Yang BB, Weisel RD, Li RK.
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| FASEB J ASEB J. 2013 Jul 1. [Epub ahead of print]
2013
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| 4 | TIMP1
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| Plasma TIMP1 level is a prognostic factor in patients with liver metastases.
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| Bunatova K, Pesta M, Kulda V, Topolcan O, Vrzalova J, Sutnar A, Treska V, Pecen L, Liska V.
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| Anticancer Res 32(10):4601-6.
2012
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| 5 | TIMP1
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| Overgrowth with increased proliferation of fibroblast and matrix metalloproteinase activity related to reduced TIMP1: a newly recognized syndrome?
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| Chung B, Hinek A, Keating S, Weksberg R, Shah V, Blaser S, Hawkins C, Chitayat D.
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| Am J Med Genet A 158A(10):2373-81. doi: 10.1002/ajmg.a.35570. Epub 2012 Sep 10.
2012
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| 6 | TIMP1
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| The endogenous protease inhibitor TIMP-1 mediates protection and recovery from cutaneous photodamage.
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| Yokose U, Hachiya A, Sriwiriyanont P, Fujimura T, Visscher MO, Kitzmiller WJ, Bello A, Tsuboi R, Kitahara T, Kobinger GP, Takema Y.
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| J Invest Dermatol 132(12):2800-9. doi: 10.1038/jid.2012.204. Epub 2012 Jun 21.
2012
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| 7 | MMP10, TIMP1, TIMP2
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| Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.
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| Batra J, Robinson J, Soares AS, Fields AP, Radisky DC, Radisky ES.
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| J Biol Chem 287(19):15935-46. doi: 10.1074/jbc.M112.341156. Epub 2012 Mar 16.
2012
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| 8 | CD63, TIMP1
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| Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling.
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| Egea V, Zahler S, Rieth N, Neth P, Popp T, Kehe K, Jochum M, Ries C.
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| Proc Natl Acad Sci U S A 109(6):E309-16. doi: 10.1073/pnas.1115083109. Epub 2012 Jan 5.
2012
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| 9 | CCNL1, TIMP1
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| A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells.
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| Peng L, Yanjiao M, Ai-guo W, Pengtao G, Jianhua L, Ju Y, Hongsheng O, Xichen Z.
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| Biochem Biophys Res Commun 409(2):344-9. Epub 2011 May 8.
2011
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| 10 | HAS2, TIMP1
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| Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1).
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| Bernert B, Porsch H, Heldin P.
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| J Biol Chem 286(49):42349-59. doi: 10.1074/jbc.M111.278598. Epub 2011 Oct 20. 2011
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| 11 | TIMP1
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| Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.
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| Nunes GL, Simões A, Dyszy FH, Shida CS, Juliano MA, Juliano L, Gesteira TF, Nader HB, Murphy G, Chaffotte AF, Goldberg ME, Tersariol IL, Almeida PC.
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| PLoS One 6(6):e21525. doi: 10.1371/journal.pone.0021525. Epub 2011 Jun 23.
2011
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| 12 | TIMP1
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| Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans.
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| Meissburger B, Stachorski L, Röder E, Rudofsky G, Wolfrum C.
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| Diabetologia 54(6):1468-79. doi: 10.1007/s00125-011-2093-9. Epub 2011 Mar 25.
2011
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| 13 | TIMP1
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| Elevated plasma levels of tissue inhibitors of metalloproteinase-1 and their overexpression in muscle in human and mouse muscular dystrophy.
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| Sun G, Haginoya K, Chiba Y, Uematsu M, Hino-Fukuyo N, Tanaka S, Onuma A, Iinuma K, Tsuchiya S.
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| J Neurol Sci 297(1-2):19-28. doi: 10.1016/j.jns.2010.06.031. Epub 2010 Jul 23.
2010
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| 14 | TIMP1
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| Role of tissue inhibitor of metalloproteinases-1 in the development of autoimmune lymphoproliferation.
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| Boggio E, Indelicato M, Orilieri E, Mesturini R, Mazzarino MC, Campagnoli MF, Ramenghi U, Dianzani U, Chiocchetti A.
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| Haematologica 95(11):1897-904. doi: 10.3324/haematol.2010.023085. Epub 2010 Jun 30.
2010
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| 15 | TIMP1
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| The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.
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| Grossman M, Tworowski D, Dym O, Lee MH, Levy Y, Murphy G, Sagi I.
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| Biochemistry 49(29):6184-92. doi: 10.1021/bi902141x.
2010
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| 16 | TIMP1, TWIST1
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| Negative regulation of TIMP1 is mediated by transcription factor TWIST1.
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| Okamura H, Yoshida K, Haneji T.
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| Int J Oncol 35(1):181-6.
2009
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| 17 | TIMP1
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| A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.
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| Ould-yahoui A, Tremblay E, Sbai O, Ferhat L, Bernard A, Charrat E, Gueye Y, Lim NH, Brew K, Risso JJ, Dive V, Khrestchatisky M, Rivera S.
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| PLoS One 4(12):e8289. doi: 10.1371/journal.pone.0008289.
2009
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| 18 | PTPN6, TIMP1
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| TIMP1 induces CD44 expression and the activation and nuclear translocation of SHP1 during the late centrocyte/post-germinal center B cell differentiation.
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| Kim YS, Seo DW, Kong SK, Lee JH, Lee ES, Stetler-Stevenson M, Stetler-Stevenson WG.
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| Cancer Lett 269(1):37-45. Epub 2008 May 23.
2008
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| 19 | TIMP1,ZBTB16
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| TIMP-1 regulates cell proliferation by interacting with the ninth zinc finger domain of PLZF.
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| Rho SB, Chung BM, Lee JH.
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| J Cell Biochem 101(1):57-67. 2007
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| 20 | TIMP3, TIMP1, TIMP2, TIMP4
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| Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1.
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| Lee MH, Atkinson S, Murphy G.
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| J Biol Chem 282(9):6887-98. Epub 2007 Jan 3. 2007
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| 21 | MMP9, TIMP1, TWIST1
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| Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1.
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| Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M.
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| Biochem J 405(3):547-58. 2007
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| 22 | TIMP1
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| Identification of alternatively spliced TIMP-1 mRNA in cancer cell lines and colon cancer tissue.
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| Usher PA, Sieuwerts AM, Bartels A, Lademann U, Nielsen HJ, Holten-Andersen L, Foekens JA, Brünner N, Offenberg H.
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| Mol Oncol 1(2):205-15. Epub 2007 May 21.
2007
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| 23 | TIMP1, MMP2
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| Keratoconus: matrix metalloproteinase-2 activation and TIMP modulation.
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| Smith VA, Matthews FJ, Majid MA, Cook SD.
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| Biochim Biophys Acta 1762(4):431-9. Epub 2006 Feb 17. 2006
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| 24 | TIMP1
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| Tissue inhibitors of metalloproteinases-1 (TIMP-1) and -2(TIMP-2) are major serum factors that stimulate the TIMP-1 gene in human gingival fibroblasts.
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| Guo XK, Zhao WQ, Kondo C, Shimojo N, Yamashita K, Aoki T, Hayakawa T.
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| Biochim Biophys Acta 1763(3):296-304. Epub 2006 Mar 24. 2006
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| 25 | MMP2, TIMP1
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| MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors.
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| Jinga DC, Blidaru A, Condrea I, Ardeleanu C, Dragomir C, Szegli G, Stefanescu M, Matache C.
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| J Cell Mol Med 10(2):499-510. 2006
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| 26 | TIMP1
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| TIMP-1 stimulates proliferation of human aortic smooth muscle cells and Ras effector pathways.
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| Akahane T, Akahane M, Shah A, Thorgeirsson UP.
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| Biochem Biophys Res Commun 324(1):440-5. 2004
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| 27 | SPHK1, TIMP1
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| Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
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| Yamanaka M, Shegogue D, Pei H, Bu S, Bielawska A, Bielawski J, Pettus B, Hannun YA, Obeid L, Trojanowska M.
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| J Biol Chem 279(52):53994-4001. Epub 2004 Oct 12. 2004
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| 28 | TIMP1
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| Variability of X chromosome inactivation: effect on levels of TIMP1 RNA and role of DNA methylation.
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| Anderson CL, Brown CJ.
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| Hum Genet 110(3):271-8. 2002
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| 29 | TIMP1
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| TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension.
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| Lindsay MM, Maxwell P, Dunn FG.
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| Hypertension 40(2):136-41. 2002
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| 30 | SYN1, SYN2, SYN3, SYN4, TIMP1, TIMP2, TIMP3, TIMP4
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| Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human.
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| Pohar N, et al.
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| Genomics 57(2):293-6. 1999
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| 31 | TIMP1
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| Tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) distribution in normal and pathological human bone.
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| Bord S, et al.
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| Bone 24(3):229-35. 1999
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| 32 | TIMP1, TIMP2
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| Expression of matrix metalloproteinases (MMP-2 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in acute myelogenous leukaemia blasts: comparison with normal bone marrow cells.
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| Janowska-Wieczorek A, et al.
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| Br J Haematol 105(2):402-11. 1999
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| 33 | TIMP1
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| Polymorphic X-chromosome inactivation of the human TIMP1 gene.
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| Anderson CL, et al.
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| Am J Hum Genet 65(3):699-708 1999
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| 34 | IL6, MMP9, TIMP1
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| Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas.
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| Kossakowska AE, Edwards DR, Prusinkiewicz C, Zhang MC, Guo D, Urbanski SJ, Grogan T, Marquez LA, Janowska-Wieczorek A.
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| Blood 94(6):2080-9 1999
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| 35 | TIMP1, TIMP2, TIMP3, TIMP4
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| Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.
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| Gomez DE, et al.
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| Eur J Cell Biol 74(2):111-22. Review. 1997
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| 36 | TIMP1
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| The gene for tissue inhibitor of metalloproteinases (TIMP) is located within an intron of the synapsin I gene on the X chromosome.
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| Derry JM, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2061-2062. 1991
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| 37 | CSNB1A, TIMP1
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| The locus for X-chromosomal congenital stationary night blindness is closely linked to TIMP in two families but not in a third one.
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| Li Y, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2075. 1991
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| 38 | TIMP1
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| PCR detection of existing and new polymorphism at the TIMP locus.
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| Aldred MA, et al.
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| Nucleic Acids Res 19 : 1165. 1991
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| 39 | TIMP1
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| Regional localization of the TIMP gene on the human X chromosome. Extension of a conserved synteny and linkage group on proximal Xp.
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| Willard HF, et al.
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| Hum Genet 81 : 234-238. 1989
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| 40 | TIMP1
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| Mapping the breakpoint at Xp11.2 in synovial sarcoma.
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| Gilgenkrantz S, et al.
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| Cytogenet Cell Genet 51 : 1004. 1989
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| 41 | TIMP1, PGK1, TBC1D25, DXS132, DXS153
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| Genetic linkage analysis of nine loci in pericentromeric region of the human X chromosome.
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| Mahtani MM, et al.
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| (HGM10) Cytogenet Cell Genet 51 : 1038. 1989
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| 42 | TIMP1
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| Chromosomal assignment of the gene encoding the human tissue inhibitor of metalloproteinases to Xp11.1-p11.4.
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| Spurr NK, et al.
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| Ann Hum Genet 51 : 189-194. 1987
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| 43 | TIMP1
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| Localization of the gene encoding human erythroid-potentiating activity to chromosome region Xp11.1----Xp11.4.
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| Huebner K, Isobe M, Gasson JC, Golde DW, Croce CM.
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| Am J Hum Genet 38 : 819-826. 1986
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| 44 | TIMP1
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| RFLP detected by an X-linked cDNA encoding erythroid-potentiating activity/tissue inhibitor of metalloproteinase (EPA/TIMP).
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| Durfy SJ, et al.
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| Nucleic Acids Res 14 : 9226. 1986
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| 45 | TIMP1
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| Sequence of human tissue inhibitor metalloproteinases and its identity to erythroid-potentiating activity.
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| Docherty AJP, et al.
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| Nature 318 : 66-69. 1985
|