1 | TGFB2, TGFB3
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| TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
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| Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR.
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| Sci Transl Med. Aug 4;13(605):eabe0407. doi: 10.1126/scitranslmed.abe040 2021
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2 | TGFB3
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| Mechanism of TGF-β3 promoting chondrogenesis in human fat stem cells.
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| Li D, Ma X, Zhao T.
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| Biochem Biophys Res Commun. Oct 1;530(4):725-731. doi: 10.1016/j.bbrc.2020.06.147. Epub 2020 Aug 8 2020
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3 | TGFB3
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| Polymorphisms of TGF-β1 and TGF-β3 in Chinese women with gestational diabetes mellitus
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| Xu Y, Wei C, Wu C, Han M, Wang J, Hou H, Zhang L, Liu S, Chen Y.
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| BMC Pregnancy Childbirth Dec 7;20(1):759. doi: 10.1186/s12884-020-03459-w. 2020
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4 | MUC5AC, NOX4, TGFB3
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| TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway.
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| Zhang Y, Tang HM, Liu CF, Yuan XF, Wang XY, Ma N, Xu GF, Wang SP, Deng J, Wang X.
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| Mediators Inflamm. Dec 31;2019:3153240. doi: 10.1155/2019/3153240. 2019
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5 | TGFB3
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| Biological Role and Therapeutic Targeting of TGF-β3 in Glioblastoma
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| Seystahl K, Papachristodoulou A, Burghardt I, Schneider H, Hasenbach K, Janicot M, Roth P, Weller M.
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| Mol Cancer Ther. Jun;16(6):1177-1186. doi: 10.1158/1535-7163.MCT-16-0465. Epub 2017 Apr 4. 2017
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6 | LDS5, TGFB3
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| Mutations in a TGF-β ligand, TGFB3, cause syndromic aortic aneurysms and dissections
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| Bertoli-Avella AM, Gillis E, Morisaki H, Verhagen JMA, de Graaf BM, van de Beek G, Gallo E, Kruithof BPT, Venselaar H, Myers LA, Laga S, Doyle AJ, Oswald G, van Cappellen GWA, Yamanaka I, van der Helm RM, Beverloo B, de Klein A, Pardo L, Lammens M, Evers C, Devriendt K, Dumoulein M, Timmermans J, Bruggenwirth HT, Verheijen F, Rodrigus I, Baynam G, Kempers M, Saenen J, Van Craenenbroeck EM, Minatoya K, Matsukawa R, Tsukube T, Kubo N, Hofstra R, Goumans MJ, Bekkers JA, Roos-Hesselink JW, van de Laar IMBH, Dietz HC, Van Laer L, Morisaki T, Wessels MW, Loeys BL.
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| J Am Coll Cardiol. Apr 7;65(13):1324-1336. doi: 10.1016/j.jacc.2015.01.040. 2015
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7 | TGFB3
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| TGFβ3 (TGFB3) polymorphism is associated with male infertility. PMID:
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| Droździk M, Kaczmarek M, Malinowski D, Broś U, Kazienko A, Kurzawa R, Kurzawski M.
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| Sci Rep. 2015 Nov 27;5:17151. doi: 10.1038/srep17151. 2015
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8 | TGFB1, TGFB2, TGFB3
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| Role of TGF-β3 in the regulation of immune responses
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| Okamura T, Morita K, Iwasaki Y, Inoue M, Komai T, Fujio K, Yamamoto K.
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| Clin Exp Rheumatol. Jul-Aug;33(4 Suppl 92):S63-9. Epub 2015 Oct 12. 2015
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9 | LDS5, TGFB3
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| A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome
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| Rienhoff HY Jr, Yeo CY, Morissette R, Khrebtukova I, Melnick J, Luo S, Leng N, Kim YJ, Schroth G, Westwick J, Vogel H, McDonnell N, Hall JG, Whitman M.
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| Am J Med Genet A. Aug;161A(8):2040-6. doi: 10.1002/ajmg.a.36056. Epub 2013 Jul 3. 2013
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10 | FOXE1, MSX1, TGFB3
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| MSX1 and TGF-beta3 are novel target genes functionally regulated by FOXE1.
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| Venza I, Visalli M, Parrillo L, De Felice M, Teti D, Venza M.
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| Hum Mol Genet 20(5):1016-25. Epub 2010 Dec 20.
2011
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11 | TGFB3
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| Tgf-beta-mediated FasL-Fas-Caspase pathway is crucial during palatogenesis.
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| Huang X, Yokota T, Iwata J, Chai Y.
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| J Dent Res 90(8):981-7. Epub 2011 May 18.
2011
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12 | TGFB3
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| Effects of p-CREB-1 on transforming growth factor-β3 auto-regulation in hepatic stellate cells.
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| Deng L, Li Y, Huang JM, Zhou G, Qian W, Xu K.
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| J Cell Biochem 112(4):1046-54. doi: 10.1002/jcb.23017.
2011
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13 | TGFB3
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| Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression.
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| He F, Xiong W, Wang Y, Li L, Liu C, Yamagami T, Taketo MM, Zhou C, Chen Y.
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| Dev Biol 350(2):511-9. Epub 2010 Dec 23.
2011
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14 | TGFB1, TGFB3
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| Latent TGF-β structure and activation.
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| Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA.
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| Nature 474(7351):343-9. doi: 10.1038/nature10152.
2011
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15 | TGFB3
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| The expression of TGF-β3 for epithelial-mesenchyme transdifferentiated MEE in palatogenesis.
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| Nakajima A, Tanaka E, Ito Y, Maeno M, Iwata K, Shimizu N, Shuler CF.
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| J Mol Histol 41(6):343-55. Epub 2010 Oct 22.
2010
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16 | TGFB3
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| Regulation of blood-testis barrier dynamics by TGF-beta3 is a Cdc42-dependent protein trafficking event.
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| Wong EW, Mruk DD, Lee WM, Cheng CY.
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| Proc Natl Acad Sci U S A 107(25):11399-404. Epub 2010 Jun 7.
2010
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17 | TGFB3
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| Transforming growth factor beta-3 and environmental factors and cleft lip with/without cleft palate.
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| Guo Z, Huang C, Ding K, Lin J, Gong B.
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| DNA Cell Biol 29(7):375-80.
2010
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18 | TGFB3
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| TGFbeta3 is expressed in differentiating muscle of the embryonic mouse tongue.
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| Yamane A, Fukui T, Suga T, Iida R, Morito M.
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| Int J Dev Biol 54(1):221-6.
2010
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19 | TGFB3
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| TGF-beta3 and cancer: a review.
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| Laverty HG, Wakefield LM, Occleston NL, O'Kane S, Ferguson MW.
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| Cytokine Growth Factor Rev 20(4):305-17. Epub 2009 Aug 4. Review.
2009
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20 | TGFB1, TGFB3
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| Interactions between TGF-beta1 and TGF-beta3 and their role in medial edge epithelium cell death and palatal fusion in vitro.
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| Murillo J, Maldonado E, Barrio MC, Del Río A, López Y, Martínez-Sanz E, González I, Martín C, Casado I, Martínez-Alvarez C.
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| Differentiation 77(2):209-20. Epub 2008 Nov 29.
2009
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21 | TGFB3
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| TGFB3 displays parent-of-origin effects among central Europeans with nonsyndromic cleft lip and palate.
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| Reutter H, Birnbaum S, Mende M, Lauster C, Schmidt G, Henschke H, Saffar M, Martini M, Lauster R, Schiefke F, Reich RH, Braumann B, Scheer M, Knapp M, Nöthen MM, Kramer FJ, Mangold E.
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| J Hum Genet 53(7):656-61. Epub 2008 May 15.
2008
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22 | TGFB3
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| Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3.
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| Medici D, Hay ED, Olsen BR.
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| Mol Biol Cell 19(11):4875-87. Epub 2008 Sep 17.
2008
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23 | TGFB3
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| Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains.
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| Martínez-Sanz E, Del Río A, Barrio C, Murillo J, Maldonado E, Garcillán B, Amorós M, Fuerte T, Fernández A, Trinidad E, Rabadán MA, López Y, Martínez ML, Martínez-Alvarez C.
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| Differentiation 76(4):417-30.
2008
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24 | TGFB3
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| Bone formation zones in heterotopic ossifications: histologic findings and increased expression of bone morphogenetic protein 2 and transforming growth factors beta2 and beta3.
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| Toom A, Arend A, Gunnarsson D, Ulfsparre R, Suutre S, Haviko T, Selstam G.
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| Calcif Tissue Int 80(4):259-67. Epub 2007 Apr 1. 2007
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25 | TGFB3
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| A large-scale genetic association study of ossification of the posterior longitudinal ligament of the spine.
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| Horikoshi T, Maeda K, Kawaguchi Y, Chiba K, Mori K, Koshizuka Y, Hirabayashi S, Sugimori K, Matsumoto M, Kawaguchi H, Takahashi M, Inoue H, Kimura T, Matsusue Y, Inoue I, Baba H, Nakamura K, Ikegawa S.
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| Hum Genet 119(6):611-6. Epub 2006 Apr 12. 2006
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26 | PAX9, TGFB3
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| PAX9 and TGFB3 are linked to susceptibility to nonsyndromic cleft lip with or without cleft palate in the Japanese: population-based and family-based candidate gene analyses.
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| Ichikawa E, Watanabe A, Nakano Y, Akita S, Hirano A, Kinoshita A, Kondo S, Kishino T, Uchiyama T, Niikawa N, Yoshiura K.
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| J Hum Genet 51(1):38-46. Epub 2005 Oct 25. 2006
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27 | ARVD1, TGFB3
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| Regulatory mutations in transforming growth factor-beta3 gene cause arrhythmogenic right ventricular cardiomyopathy type 1.
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| Beffagna G, Occhi G, Nava A, Vitiello L, Ditadi A, Basso C, Bauce B, Carraro G, Thiene G, Towbin JA, Danieli GA, Rampazzo A.
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| Cardiovasc Res 65(2):366-73. 2005
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28 | ARVD1, ANGEL1, VASH1, POMT2, TGFB3
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| Arrhythmogenic right ventricular cardiomyopathy type 1 (ARVD1): confirmation of locus assignment and mutation screening of four candidate genes.
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| Rampazzo A, Beffagna G, Nava A, Occhi G, Bauce B, Noiato M, Basso C, Frigo G, Thiene G, Towbin J, Danieli GA.
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| Eur J Hum Genet 11(1):69-76. 2003
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29 | MED15,NODAL,TGFB1,TGFB2,TGFB3
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| A component of the ARC/Mediator complex required for TGFbeta/Nodal signalling.
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| Kato Y, Habas R, Katsuyama Y, Naar AM, He X.
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| Nature 418(6898):641-6. 2002
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30 | TGFB2, TGFB1, TGFB3, TGFBR1, TGFBR2, TGFBR3
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| Molecular analysis of TGF-(beta)s and their receptors in human keratinocyte cell lines of different biological behaviour.
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| Bachmeier BE, Ruoss I, Hagedorn HG, Nerlich AG.
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| Int J Mol Med 10(4):371-6. 2002
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31 | PGF, NEUROD4, TGFB3
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| An expression map from human chromosome 14q24.3.
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| Sharma V, Poorkaj P, Hisama F, Bonnycastle L, Yu CE, Massa H, Trask B, Clancy KP, Patterson D, Weissman SM, Schellenberg GD.
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| Genomics 47(2):314-8. 1998
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32 | MSX1, TGFB3, OFC5
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| Association of MSX1 and TGFB3 with nonsyndromic clefting in humans.
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| Lidral AC, Romitti PA, Basart AM, Doetschman T, Leysens NJ, Daack-Hirsch S, Semina EV, Johnson LR, Machida J, Burds A, Parnell TJ, Rubenstein JL, Murray JC.
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| Am J Hum Genet 63 : 557-568. 1998
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33 | TGFB3
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| Transforming growth factor-beta3 is required for secondary palate fusion.
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| Proetzel G, et al.
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| Nat Genet 11 : 409-414. 1995
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34 | TGFB3
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| Abnormal lung development and cleft palate in mice lacking TGF-beta3 indicates defects of epithelial-mesenchymal interaction.
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| Kaartinen V, et al.
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| Nat Genet 11 : 415-421. 1995
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35 | TGFB2, TGFB3
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| Chromosomal mapping of genes for transforming growth factors beta-2 and beta-3 in man and mouse : dispersion of TGB-beta gene family.
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| Barton DE, et al.
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| Oncogene Res 3 : 323-331. 1988
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36 | TGFB3
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| Transforming growth factor type beta 3 maps to human chromosome 14, region q23-q24.
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| ten Dijke P, et al.
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| Oncogene 3 : 721-724. 1988
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