Citations for
1ICAM1, TGFA
Transforming growth factor alpha promotes osteosarcoma metastasis by ICAM-1 and PI3K/Akt signaling pathway.
Hou CH, Lin FL, Tong KB, Hou SM, Liu JF.
Biochem Pharmacol 89(4):453-63. doi: 10.1016/j.bcp.2014.03.010. Epub 2014 Mar 28. 2014
2P4HTM, TGFA
PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α.
Klotzsche-von Ameln A, Prade I, Grosser M, Kettelhake A, Rezaei M, Chavakis T, Flamme I, Wielockx B, Breier G.
Mol Cancer Res 11(11):1337-48. doi: 10.1158/1541-7786.MCR-13-0201. Epub 2013 Sep 18. 2013
3MMP1, TGFA
Transforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation.
Tahara H, Sato K, Yamazaki Y, Ohyama T, Horiguchi N, Hashizume H, Kakizaki S, Takagi H, Ozaki I, Arai H, Hirato J, Jesenofsky R, Masamune A, Mori M.
Lab Invest 93(6):720-32. doi: 10.1038/labinvest.2013.59. Epub 2013 Apr 22. 2013
4IRF6, TGFA
Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate.
Letra A, Fakhouri W, Fonseca RF, Menezes R, Kempa I, Prasad JL, McHenry TG, Lidral AC, Moreno L, Murray JC, Daack-Hirsch S, Marazita ML, Castilla EE, Lace B, Orioli IM, Granjeiro JM, Schutte BC, Vieira AR.
PLoS One 7(9):e45441. doi: 10.1371/journal.pone.0045441. Epub 2012 Sep 20. 2012
5TGFA
Transforming growth factor alpha (TGFα) regulates granulosa cell tumor (GCT) cell proliferation and migration through activation of multiple pathways.
Wang C, Lv X, Jiang C, Cordes CM, Fu L, Lele SM, Davis JS.
PLoS One 7(11):e48299. doi: 10.1371/journal.pone.0048299. Epub 2012 Nov 14. 2012
6TGFA
Transforming growth factor alpha controls the transition from hypertrophic cartilage to bone during endochondral bone growth.
Usmani SE, Pest MA, Kim G, Ohora SN, Qin L, Beier F.
Bone 51(1):131-41. doi: 10.1016/j.bone.2012.04.012. Epub 2012 May 1. 2012
7MMP9, PPARD, TGFA
AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes.
Meissner M, Berlinski B, Doll M, Hrgovic I, Laubach V, Reichenbach G, Kippenberger S, Gille J, Kaufmann R.
Exp Dermatol 20(5):425-9. doi: 10.1111/j.1600-0625.2011.01253.x. 2011
8TGFA
Transforming growth factor-α attenuates hepatic fibrosis: possible involvement of matrix metalloproteinase-1.
Ohyama T, Yamazaki Y, Sato K, Horiguchi N, Ichikawa T, Kakizaki S, Takagi H, Mori M.
Liver Int 31(4):572-84. doi: 10.1111/j.1478-3231.2011.02475.x. Epub 2011 Feb 15. 2011
9EGF, TGFA
Potential for functional redundancy in EGF and TGFalpha signaling in desmoid cells: a cDNA microarray analysis.
Trang SH, Joyner DE, Damron TA, Aboulafia AJ, Randall RL.
Growth Factors 28(1):10-23. 2010
10TGFA
Evidence that TGFA influences risk to cleft lip with/without cleft palate through unconventional genetic mechanisms.
Sull JW, Liang KY, Hetmanski JB, Wu T, Fallin MD, Ingersoll RG, Park JW, Wu-Chou YH, Chen PK, Chong SS, Cheah F, Yeow V, Park BY, Jee SH, Jabs EW, Redett R, Scott AF, Beaty TH.
Hum Genet 126(3):385-94. Epub 2009 May 15.PMID: 19444471 2009
11TGFA
Transforming growth factor-alfa gene (TGFA), human tooth agenesis, and evidence of segmental uniparental isodisomy.
Callahan N, Modesto A, Deeley K, Meira R, Vieira AR.
Eur J Oral Sci 117(1):20-6.PMID: 19196314 2009
12AREG, EREG, TGFA
Differential effects of EGFR ligands on endocytic sorting of the receptor.
Roepstorff K, Grandal MV, Henriksen L, Knudsen SL, Lerdrup M, Grøvdal L, Willumsen BM, van Deurs B.
Traffic 10(8):1115-27. doi: 10.1111/j.1600-0854.2009.00943.x. Epub 2009 May 19. 2009
13CD9, TGFA
Association of tetraspanin CD9 with transmembrane TGF{alpha} confers alterations in cell-surface presentation of TGF{alpha} and cytoskeletal organization.
Imhof I, Gasper WJ, Derynck R.
J Cell Sci 121(Pt 13):2265-74. Epub 2008 Jun 10.PMID: 18544636 2008
14NKD1, NKD2, TGFA
EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.
Ding W, Li C, Hu T, Graves-Deal R, Fotia AB, Weissman AM, Coffey RJ.
Proc Natl Acad Sci U S A 105(36):13433-8. Epub 2008 Aug 29.PMID: 18757723 2008
15TGFA
Expression of intermediate filaments, EGF and TGF-alpha in early human kidney development.
Carev D, Saraga M, Saraga-Babic M.
J Mol Histol 39(2):227-35. Epub 2007 Dec 15.PMID: 18080773 2008
16NKD2, TGFA
Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.
Li C, Hao M, Cao Z, Ding W, Graves-Deal R, Hu J, Piston DW, Coffey RJ.
Mol Biol Cell 18(8):3081-93. Epub 2007 Jun 6.PMID: 17553928 2007
17TGFA, OFC2
Association between the transforming growth factor alpha gene and nonsyndromic oral clefts: a HuGE review.
Vieira AR.
Am J Epidemiol 163(9):790-810. Epub 2006 Feb 22. Review. 2006
18TGFA, SATB2, OFC2, OFC7
Analysis of candidate genes on chromosome 2 in oral cleft case-parent trios from three populations.
Beaty TH, Hetmanski JB, Fallin MD, Park JW, Sull JW, McIntosh I, Liang KY, Vanderkolk CA, Redett RJ, Boyadjiev SA, Jabs EW, Chong SS, Cheah FS, Wu-Chou YH, Chen PK, Chiu YF, Yeow V, Ng IS, Cheng J, Huang S, Ye X, Wang H, Ingersoll R, Scott AF.
Hum Genet 120(4):501-18. Epub 2006 Sep 5. 2006
19NKD2, TGFA
Structural studies of human Naked2: a biologically active intrinsically unstructured protein.
Hu T, Krezel AM, Li C, Coffey RJ.
Biochem Biophys Res Commun 350(4):911-5. Epub 2006 Oct 2.PMID: 17045239 2006
20MAGI3, TGFA
Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.
Franklin JL, Yoshiura K, Dempsey PJ, Bogatcheva G, Jeyakumar L, Meise KS, Pearsall RS, Threadgill D, Coffey RJ.
Exp Cell Res 303(2):457-70. 2005
21NKD1, NKD2, TGFA
Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells.
Li C, Franklin JL, Graves-Deal R, Jerome WG, Cao Z, Coffey RJ.
Proc Natl Acad Sci U S A 101(15):5571-6. Epub 2004 Apr 2.PMID: 15064403 2004
22GORASP2, TGFA
Transmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55.
Kuo A, Zhong C, Lane WS, Derynck R.
EMBO J 19(23):6427-39. 2000
23ALMS1, TGFA
TGFA : exon-intron structure and evaluation as a candidate gene for Alstršm syndrome.
Collin GB, et al.
Clin Genet 55 : 61-62. 1999
24OFC2, TGFA
Transforming growth factor-alpha (TGFA): genomic structure, boundary sequences, and mutation analysis in nonsyndromic cleft Lip/Palate and cleft palate only.
Machida J, Yoshiura Ki, Funkhauser CD, Natsume N, Kawai T, Murray JC.
Genomics 61(3):237-42 1999
25OFC2, TGFA
Lack of linkage disequilibrium between transforming growth factor alpha Taq I polymorphism and cleft lip with or without cleft palate in families from northeastern Italy.
Scapoli L, Pezzetti F, Carinci F, Martinelli M, Carinci P, Tognon M.
Am J Med Genet 75(2):203-6. 1998
26OFC2, TGFA
Application of transmission disequilibrium tests to nonsyndromic oral clefts : including candidate genes and environmental exposures in the models.
Maestri NE, Beaty TH, Hetmanski J, Smith EA, McIntosh I, Wyszynski DF, Liang KY, Duffy DL, VanderKolk C.
Am J Med Genet 73(3):337-44. 1997
27TGFA
A PCR method for detecting polymorphism in the TGFA gene.
Basart AM, et al.
Hum Mol Genet 3 : 678. 1994
28TGFA, OFC2
Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate.
Feng H, et al.
Am J Hum Genet 55 : 932-936. 1994
29TGFA
Transforming growth factor-alpha : characterization of the BamHI, Rsal, and Taql polymorphic regions.
Qian JF, et al.
Am J Hum Genet 53 : 168-175. 1993
30OFC2, TGFA
Association of transforming growth-factor alpha gene polymorphisms with nonsyndromic cleft palate only (CPO).
Shiang R, et al.
Am J Hum Genet 53 : 836-843. 1993
31TGFA
Expression of epidermal growth factor (EGF) receptor and its ligands, EGF and transforming growth factor-alpha, in human fallopian tubes.
Lei ZM, Rao CV.
Endocrinology 131(2):947-57.PMID: 1639032 1992
32TGFA, OFC2
Non-syndromic cleft lip and palate : association and linkage studies with transforming growth factor alpha gene.
Holder SE, et al.
(HGM11) Cytogenet Cell Genet 58 : 1869-1870. 1991
33TGFA, OFC2
No association of genetic variation of the transforming growth factor-alpha with cleft-lip and palate.
Qian JF, et al.
Am J Hum Genet 49S : 397. 1991
34TGFA
A novel BamHI polymorphism for the human transforming growth factor alpha gene (TGF-alpha).
Qian JF, et al.
Nucleic Acids Res 19 : 6665. 1991
35OFC2, TGFA
Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate.
Ardinger HH, et al.
Am J Hum Genet 45 : 348-353. 1989
36TGFA
A Taq I polymorphism for the human transforming growth factor alpha gene (TGFA).
Hayward NK, et al.
Nucleic Acids Res 15 : 5503. 1987
37TGFA
RFLPs for transforming growth factor alpha (TGFA) gene at 2p13.
Murray JC, et al.
Nucleic Acids Res 14 : 7136. 1986
38TGFA
The gene for human transforming growth factor alpha is on the short arm of chromosome 2.
Tricoli JV, et al.
Cytogenet Cell Genet 42 : 94-98. 1986
39TGFA
Assignment of the gene coding for human TGFalpha to chromosome 2p13.
Tricoli JV, et al.
(HGM8) Cytogenet Cell Genet 40 : 762. 1985
40TGFA
Transforming growth factor alpha gene (TGFA) maps to human chromosome 2 close to the breakpoint of the t(2;8) variant translocation in Burkitt lymphoma.
Brissenden JE, et al.
(HGM8) Cytogenet Cell Genet 40 : 589. 1985
41TGFA
Mapping of transforming growth factor alpha gene on human chromosome 2 close to the breakpoint of the Burkitt's lymphoma t(2;8) variant translocation.
Brissenden JE, et al.
Cancer Res 45 : 5593-5597. 1985