| 1 | EPP, FECH, TFRC
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| Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria.
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| Mirmiran A, Schmitt C, Lefebvre T, Manceau H, Daher R, Oustric V, Poli A, Lacapère JJ, Moulouel B, Puy H, Karim Z, Peoc'h K, Lenglet H, Simonin S, Deybach JC, Nicolas G, Gouya L.
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| Am J Hum Genet 104(2):341-347. doi: 10.1016/j.ajhg.2018.12.021. Epub 2019 Jan 31.
2019
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| 2 | CRAT, NBIA7, REPS1, TFRC
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| Impaired Transferrin Receptor Palmitoylation and Recycling in Neurodegeneration with Brain Iron Accumulation.
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| Drecourt A, Babdor J, Dussiot M, Petit F, Goudin N, Garfa-Traoré M, Habarou F, Bole-Feysot C, Nitschké P, Ottolenghi C, Metodiev MD, Serre V, Desguerre I, Boddaert N, Hermine O, Munnich A, Rötig A.
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| Am J Hum Genet 102(2):266-277. doi: 10.1016/j.ajhg.2018.01.003.
2018
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| 3 | TFRC
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| Modulation of Melanotransferrin and Transferrin Receptor 1 (TFRC)- and CD44-based Signaling for TFRC Up-regulation in Human Melanoma Cells.
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| Laube F, Glanz D.
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| Anticancer Res 37(6):3001-3007.
2017
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| 4 | FTL, TFRC
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| Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value.
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| Rosager AM, Sørensen MD, Dahlrot RH, Hansen S, Schonberg DL, Rich JN, Lathia JD, Kristensen BW.
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| PLoS One 12(8):e0182954. doi: 10.1371/journal.pone.0182954. eCollection 2017.
2017
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| 5 | IMD46, TFRC
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| A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
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| Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, Abu-Shukair M, Vatsayan A, Silver E, Ahuja S, Davies EG, Sola-Visner M, Ohsumi TK, Andrews NC, Notarangelo LD, Fleming MD, Al-Herz W, Kunkel LM, Geha RS.
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| Nat Genet 48(1):74-8. doi: 10.1038/ng.3465. Epub 2015 Dec 7.
2016
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| 6 | EGFR, TFRC
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| EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1.
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| Wang B, Zhang J, Song F, Tian M, Shi B, Jiang H, Xu W, Wang H, Zhou M, Pan X, Gu J, Yang S, Jiang L, Li Z.
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| Cancer Lett 381(2):331-40. doi: 10.1016/j.canlet.2016.08.006. Epub 2016 Aug 11.
2016
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| 7 | TFRC
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| Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.
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| Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H.
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| Sci Rep 6:21019. doi: 10.1038/srep21019.
2016
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| 8 | TFRC
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| Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart.
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| Xu W, Barrientos T, Mao L, Rockman HA, Sauve AA, Andrews NC.
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| Cell Rep 13(3):533-45. doi: 10.1016/j.celrep.2015.09.023. Epub 2015 Oct 8.
2015
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| 9 | TFRC
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| H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner.
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| Sakamoto S, Kawabata H, Masuda T, Uchiyama T, Mizumoto C, Ohmori K, Koeffler HP, Kadowaki N, Takaori-Kondo A.
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| PLoS One 10(10):e0139915. doi: 10.1371/journal.pone.0139915. eCollection 2015.
2015
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| 10 | TFRC
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| Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.
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| Chen AC, Donovan A, Ned-Sykes R, Andrews NC.
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| Proc Natl Acad Sci U S A 112(37):11714-9. doi: 10.1073/pnas.1511701112. Epub 2015 Aug 31.
2015
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| 11 | TFRC
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| Regulation of mitochondrial morphology and function by stearoylation of TFR1.
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| Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA.
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| Nature 525(7567):124-8. doi: 10.1038/nature14601. Epub 2015 Jul 27.
2015
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| 12 | SNX4, TFRC, TXLNA
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| α-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor.
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| Sakane H, Horii Y, Nogami S, Kawano Y, Kaneko-Kawano T, Shirataki H.
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| PLoS One 9(4):e93509. doi: 10.1371/journal.pone.0093509. eCollection 2014.
2014
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| 13 | SPHK1, TFRC
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| Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1.
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| Pham DH, Powell JA, Gliddon BL, Moretti PA, Tsykin A, Van der Hoek M, Kenyon R, Goodall GJ, Pitson SM.
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| Oncogene 33(48):5559-68. doi: 10.1038/onc.2013.502. Epub 2013 Nov 25.
2014
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| 14 | IFT20, IFT52, IFT57, TFRC
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| Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system
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| Finetti F, Patrussi L, Masi G, Onnis A, Galgano D, Lucherini OM, Pazour GJ, Baldari CT.
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| J Cell Sci. May 1;127(Pt 9):1924-37. doi: 10.1242/jcs.139337. Epub 2014 Feb 19. 2014
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| 15 | SPPL2A, SPPL2B, TFRC
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| The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b.
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| Zahn C, Kaup M, Fluhrer R, Fuchs H.
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| FEBS J 280(7):1653-63. doi: 10.1111/febs.12176. Epub 2013 Mar 1.
2013
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| 16 | TFRC
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| TfR1 interacts with the IKK complex and is involved in IKK-NF-κB signalling.
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| Kenneth NS, Mudie S, Naron S, Rocha S.
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| Biochem J 449(1):275-84. doi: 10.1042/BJ20120625.
2013
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| 17 | RBSN, TFRC
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| Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.
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| Navaroli DM, Bellvé KD, Standley C, Lifshitz LM, Cardia J, Lambright D, Leonard D, Fogarty KE, Corvera S.
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| Proc Natl Acad Sci U S A 109(8):E471-80. doi: 10.1073/pnas.1115495109. Epub 2012 Jan 30.
2012
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| 18 | TFRC
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| CD71 is selectively and ubiquitously expressed at high levels in erythroid precursors of all maturation stages: a comparative immunochemical study with glycophorin A and hemoglobin A.
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| Dong HY, Wilkes S, Yang H.
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| Am J Surg Pathol 35(5):723-32. doi: 10.1097/PAS.0b013e31821247a8.
2011
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| 19 | RAB12, TFRC
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| Small GTPase Rab12 regulates constitutive degradation of transferrin receptor.
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| Matsui T, Itoh T, Fukuda M.
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| Traffic. Oct;12(10):1432-43. doi: 10.1111/j.1600-0854.2011.01240.x. Epub 2011 Jul 29. 2011
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| 20 | RAB12, TFRC
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| Small GTPase Rab12 regulates transferrin receptor degradation: Implications for a novel membrane trafficking pathway from recycling endosomes to lysosomes.
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| Matsui T, Fukuda M.
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| Cell Logist. Jul;1(4):155-158. doi: 10.4161/cl.1.4.18152. Epub 2011 Jul 1. 2011
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| 21 | FTH1, FTL, TF, TFRC
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| Binding and uptake of H-ferritin are mediated by human transferrin receptor-1.
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| Li L, Fang CJ, Ryan JC, Niemi EC, Lebrón JA, Björkman PJ, Arase H, Torti FM, Torti SV, Nakamura MC, Seaman WE.
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| Proc Natl Acad Sci U S A 107(8):3505-10. Epub 2010 Feb 4. 2010
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| 22 | APP, TFRC
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| Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
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| Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI.
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| Cell 142(6):857-67. 2010
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| 23 | TF, TFR2, TFRC
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| Characterization of the interaction between diferric transferrin and transferrin receptor 2 by functional assays and atomic force microscopy.
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| Ikuta K, Yersin A, Ikai A, Aisen P, Kohgo Y.
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| J Mol Biol 397(2):375-84. Epub 2010 Jan 22. 2010
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| 24 | TFRC
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| CD71 (transferrin receptor): an effective marker for erythroid precursors in bone marrow biopsy specimens.
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| Marsee DK, Pinkus GS, Yu H.
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| Am J Clin Pathol 134(3):429-35. doi: 10.1309/AJCPCRK3MOAOJ6AT.
2010
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| 25 | PPARGC1B, TFRC
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| Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.
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| Ishii KA, Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ, Vidal-Puig A, Ikeda K.
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| Nat Med 15(3):259-66. Epub 2009 Mar 1.
2009
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| 26 | TF, TFRC
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| A loop in the N-lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis, isothermal titration calorimetry, and epitope mapping.
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| Mason AB, Byrne SL, Everse SJ, Roberts SE, Chasteen ND, Smith VC, MacGillivray RT, Kandemir B, Bou-Abdallah F.
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| J Mol Recognit 22(6):521-9.PMID: 19693784 2009
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| 27 | TFR2, TFRC
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| The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells.
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| Herbison CE, Thorstensen K, Chua AC, Graham RM, Leedman P, Olynyk JK, Trinder D.
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| Am J Physiol Cell Physiol 297(6):C1567-75. Epub 2009 Oct 14.
2009
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| 28 | CLCN4, TFRC
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| An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice
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| Mohammad-Panah R, Wellhauser L, Steinberg BE, Wang Y, Huan LJ, Liu XD, Bear CE.
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| J Cell Sci. Apr 15;122(Pt 8):1229-37. doi: 10.1242/jcs.037317. 2009
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| 29 | SNX4, TFRC
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| SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment.
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| Traer CJ, Rutherford AC, Palmer KJ, Wassmer T, Oakley J, Attar N, Carlton JG, Kremerskothen J, Stephens DJ, Cullen PJ.
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| Nat Cell Biol 9(12):1370-80. Epub 2007 Nov 11. 2007
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| 30 | TF, TFRC
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| The mechanism of iron release from the transferrin-receptor 1 adduct.
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| Hémadi M, Ha-Duong NT, El Hage Chahine JM.
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| J Mol Biol 358(4):1125-36. Epub 2006 Mar 13.PMID: 16564538 2006
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| 31 | TFRC
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| Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis.
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| O'Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, Dang CV.
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| Mol Cell Biol 26(6):2373-86.PMID: 16508012 [ 2006
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| 32 | GABARAP, TFRC
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| Association of human transferrin receptor with GABARAP.
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| Green F, O'Hare T, Blackwell A, Enns CA.
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| FEBS Lett 518(1-3):101-6. 2002
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| 33 | FTH1, FTL, HEPH, HFE, TF, TFRC
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| Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approach.
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| Douabin-Gicquel V, Soriano N, Ferran H, Wojcik F, Palierne E, Tamim S, Jovelin T, McKie AT, Le Gall JY, David V, Mosser J.
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| Hum Genet 109(4):393-401. 2001
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| 34 | TFRC
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| Transferrin receptor is necessary for development of erythrocytes and the nervous system.
|
| Levy JE, et al.
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| Nat Genet 21(4):396-9. 1999
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| 35 | HFE, TFRC
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| Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1.
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| Fleming RE, Migas MC, Zhou X, Jiang J, Britton RS, Brunt EM, Tomatsu S, Waheed A, Bacon BR, Sly WS.
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| Proc Natl Acad Sci U S A 96(6):3143-8. 1999
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| 36 | TFRC
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| New DNA polymorphisms define ethnically distinct haplotypes in the human transferrin receptor gene.
|
| Van Landeghem GF, et al.
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| Hum Hered 48 : 245-250. 1998
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| 37 | USP7, RAB7A, TFRC
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| NotI linking/jumping clones of human chromosome 3 : mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors.
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| Kashuba VI, Gizatullin RZ, Protopopov AI, Allikmets R, Korolev S, Li J, Boldog F, Tory K, Zabarovska V, Marcsek Z, Sumegi J, Klein G, Zabarovsky ER, Kisselev L.
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| FEBS Lett 419(2-3):181-5. 1997
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| 38 | TFRC, RGCP@
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| Preliminary report on three polymorphisms : transferrin receptor on chromosome 3, and red and green cone pigment on the X chromosome.
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| Kidd JR, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 639. 1987
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| 39 | TFRC
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| Regional localization of the human transferrin receptor gene to3q26.2->qter.
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| Rabin M, et al.
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| Am J Hum Genet 37 : 1112-1116. 1985
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| 40 | TFRC
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| Chromosome 3q (22-ter) encodes the human transferrin receptor.
|
| Miller YE, et al.
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| Am J Hum Genet 35 : 573-583. 1983
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| 41 | TFRC
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| Human transferrin receptor:expression of the receptor is assigned tochromosome 3.
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| Enns CA, et al.
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| Proc Natl Acad Sci U S A 79 : 3241-3245. 1982
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| 42 | TFRC
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| Expression of human transferring receptor is controlled by a gene onchromosome 3: assignment using species specificity of a monoclonal antibody.
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| Goodfellow PN, et al.
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| Somatic Cell Genet 8 : 197-206. 1982
|