1 | PRSS3, TFPI2
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| PO-44 - Tissue factor pathway inhibitor-2 (TFPI-2) is cleaved by PRSS3: implication for tumor endothelial cells migration.
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| Ghilardi C, Anastasia A, Avigni R, Lupi M, Giavazzi R, Bani MR.
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| Thromb Res 140 Suppl 1:S192-3. doi: 10.1016/S0049-3848(16)30177-3. Epub 2016 Apr 8.
2016
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2 | PRSS3, TFPI2
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| Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2.
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| Ghilardi C, Silini A, Figini S, Anastasia A, Lupi M, Fruscio R, Giavazzi R, Bani MR.
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| Oncotarget 6(29):28389-400. doi: 10.18632/oncotarget.4949.
2015
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3 | PRSS3, TFPI2
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| Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation.
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| Yamamoto-Tanaka M, Motoyama A, Miyai M, Matsunaga Y, Matsuda J, Tsuboi R, Hibino T.
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| J Biol Chem 289(29):20026-38. doi: 10.1074/jbc.M113.543421. Epub 2014 May 28.
2014
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4 | TFPI2
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| Knockdown of TFPI-2 promotes migration and invasion of glioma cells.
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| Gessler F, Voss V, Seifert V, Gerlach R, Kögel D.
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| Neurosci Lett 497(1):49-54. Epub 2011 Apr 20.
2011
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5 | TFPI2
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| Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages.
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| Pou J, Rebollo A, Piera L, Merlos M, Roglans N, Laguna JC, Alegret M.
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| Biochim Biophys Acta 1813(6):1254-60. Epub 2011 Apr 15.
2011
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6 | TFPI2
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| Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma.
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| Jain S, Chang TT, Hamilton JP, Lin SY, Lin YJ, Evans AA, Selaru FM, Lin PW, Chen SH, Block TM, Hu CT, Song W, Meltzer SJ, Su YH.
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| PLoS One 6(11):e26799. Epub 2011 Nov 2. 2011
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7 | TFPI2
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| TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
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| Wang S, Xiao X, Zhou X, Huang T, Du C, Yu N, Mo Y, Lin L, Zhang J, Ma N, Murata M, Huang G, Zhang Z.
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| BMC Cancer 10:617. 2010
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8 | CLDN6, FBN2, RBP4, TFPI2, TMEFF2
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| Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma.
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| Tsunoda S, Smith E, De Young NJ, Wang X, Tian ZQ, Liu JF, Jamieson GG, Drew PA.
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| Oncol Rep 21(4):1067-73.
2009
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9 | TFPI2
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| A novel role for tissue factor pathway inhibitor-2 in the therapy of human esophageal carcinoma.
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| Ran Y, Pan J, Hu H, Zhou Z, Sun L, Peng L, Yu L, Sun L, Liu J, Yang Z.
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| Hum Gene Ther 20(1):41-9.
2009
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10 | TFPI2
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| Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.
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| Glöckner SC, Dhir M, Yi JM, McGarvey KE, Van Neste L, Louwagie J, Chan TA, Kleeberger W, de Bruďne AP, Smits KM, Khalid-de Bakker CA, Jonkers DM, Stockbrügger RW, Meijer GA, Oort FA, Iacobuzio-Donahue C, Bierau K, Herman JG, Baylin SB, Van Engeland M, Schuebel KE, Ahuja N.
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| Cancer Res 69(11):4691-9. Epub 2009 May 12.
2009
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11 | TFPI2
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| Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system.
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| Kempaiah P, Chand HS, Kisiel W.
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| Arch Biochem Biophys 482(1-2):58-65. Epub 2008 Dec 10.
2009
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12 | TFPI2
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| Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line.
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| Kempaiah P, Kisiel W.
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| Apoptosis 13(5):702-15.
2008
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13 | TFPI2
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| Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues.
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| Kempaiah P, Chand HS, Kisiel W.
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| Mol Cancer 6:20. 2007
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14 | TFPI2
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| Adenovirus-mediated expression of tissue factor pathway inhibitor-2 inhibits endothelial cell migration and angiogenesis.
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| Ivanciu L, Gerard RD, Tang H, Lupu F, Lupu C.
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| Arterioscler Thromb Vasc Biol 27(2):310-6. Epub 2006 Nov 30. 2007
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15 | ADAMTS1, TFPI2
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| ADAMTS1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2.
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| Torres-Collado AX, Kisiel W, Iruela-Arispe ML, Rodriguez-Manzaneque JC.
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| J Biol Chem 281(26):17827-37. Epub 2006 Apr 26. 2006
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16 | TFPI2
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| Tissue factor pathway inhibitor-2 is upregulated by vascular endothelial growth factor and suppresses growth factor-induced proliferation of endothelial cells.
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| Xu Z, Maiti D, Kisiel W, Duh EJ.
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| Arterioscler Thromb Vasc Biol 26(12):2819-25. Epub 2006 Oct 5. 2006
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17 | TFPI2
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| Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma.
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| Jiang P, Watanabe H, Okada G, Ohtsubo K, Mouri H, Tsuchiyama T, Yao F, Sawabu N.
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| Cancer Sci 97(11):1267-73. Epub 2006 Sep 5. 2006
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18 | TFPI2
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| Characterization and functional analysis of TFPI-2 gene promoter in a human choriocarcinoma cell line.
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| Hube F, Reverdiau P, Iochmann S, Cherpi-Antar C, Gruel Y.
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| Thromb Res 109(4):207-15. 2003
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19 | TFPI2
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| Transcriptional silencing of the TFPI-2 gene by promoter hypermethylation in choriocarcinoma cells.
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| Hube F, Reverdiau P, Iochmann S, Rollin J, Cherpi-Antar C, Gruel Y.
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| Biol Chem 384(7):1029-34. 2003
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20 | TFPI2
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| Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene.
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| Kamei S, Kazama Y, Kuijper JL, Foster DC, Kisiel W.
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| Biochim Biophys Acta 1517(3):430-5. 2001
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21 | TFPI2
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| Assignment of the human PP5/TFPI-2 gene to 7q22 by FISH and PCR-based human/rodent cell hybrid mapping panel analysis.
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| Miyagi Y, et al.
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| Genomics 35 : 267-268. 1996
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22 | TFPI2
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| Inhibitory properties of a novel human Kunitz-type protease inhibitor homologous to tissue factor pathway inhibitor.
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| Petersen LC, et al.
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| Biochemistry 35(1):266-72 1996
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23 | TFPI2
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| Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor.
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| Sprecher CA, et al.
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| Proc Natl Acad Sci U S A 91 : 3353-3357. 1994
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24 | TFPI2
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| cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells : identification as placental protein 5 and tissue factor pathway inhibitor-2.
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| Miyagi Y, et al.
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| J Biochem 116 : 939-942. 1994
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