Citations for
1MTOR, TFE3, TFEB
AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3
Paquette M, El-Houjeiri L, C Zirden L, Puustinen P, Blanchette P, Jeong H, Dejgaard K, Siegel PM, Pause A.
Autophagy. Dec;17(12):3957-3975. doi: 10.1080/15548627.2021.1898748. Epub 2021 Mar 18. 2021
2CDK4, CDK6, TFE3, TFEB
CDK4/6 regulate lysosome biogenesis through TFEB/TFE3. 2020 PMID:
Yin Q, Jian Y, Xu M, Huang X, Wang N, Liu Z, Li Q, Li J, Zhou H, Xu L, Wang Y, Yang C.
J Cell Biol. Aug 3;219(8):e201911036. doi: 10.1083/jcb.201911036. 2020
3FNIP1, MTOR, TFE3
Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3
Ramírez JA, Iwata T, Park H, Tsang M, Kang J, Cui K, Kwong W, James RG, Baba M, Schmidt LS, Iritani BM.
J Immunol. Dec 1;203(11):2899-2908. doi: 10.4049/jimmunol.1900395. Epub 2019 Nov 1. 2019
4ASPSCR1, TFE3
Xp11 Translocation Renal Cell Carcinoma and the Mesenchymal Counterparts: An Evolving Concept with Novel Insights on Clinicopathologic Features, Prognosis, Treatment, and Classification.
Wang XT, Xia QY, Zhou XJ, Rao Q.
Crit Rev Oncog. 22(5-6):481-497. doi: 10.1615/CritRevOncog.2017020558 2017
5CAMTA1, TFE3
Epithelioid hemangioendotheliomas with TFE3 gene translocations are compossible with CAMTA1 gene rearrangements.
Lee SJ, Yang WI, Chung WS, Kim SK.
Oncotarget 7(7):7480-8. doi: 10.18632/oncotarget.7060. 2016
6TFE3, YAP1
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma.
Antonescu CR, Le Loarer F, Mosquera JM, Sboner A, Zhang L, Chen CL, Chen HW, Pathan N, Krausz T, Dickson BC, Weinreb I, Rubin MA, Hameed M, Fletcher CD.
Genes Chromosomes Cancer 52(8):775-84. doi: 10.1002/gcc.22073. Epub 2013 Jun 5. 2013
7ESRRB, TFE3
Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.
Betschinger J, Nichols J, Dietmann S, Corrin PD, Paddison PJ, Smith A.
Cell 153(2):335-47. doi: 10.1016/j.cell.2013.03.012. 2013
8MYOG, TFE3
TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.
Naka A, Iida KT, Nakagawa Y, Iwasaki H, Takeuchi Y, Satoh A, Matsuzaka T, Ishii KA, Kobayashi K, Yatoh S, Shimada M, Yahagi N, Suzuki H, Sone H, Yamada N, Shimano H.
Biochem Biophys Res Commun 430(2):664-9. doi: 10.1016/j.bbrc.2012.11.094. Epub 2012 Dec 2. 2013
9TFE3
TFE3 Controls Lipid Metabolism in Adipose Tissue of Male Mice by Suppressing Lipolysis and Thermogenesis.
Fujimoto Y, Nakagawa Y, Satoh A, Okuda K, Shingyouchi A, Naka A, Matsuzaka T, Iwasaki H, Kobayashi K, Yahagi N, Shimada M, Yatoh S, Suzuki H, Yogosawa S, Izumi T, Sone H, Urayama O, Yamada N, Shimano H.
Endocrinology ndocrinology. 2013 Jul 24. [Epub ahead of print] 2013
10ASPSCR1, TFE3
Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein.
Kobos R, Nagai M, Tsuda M, Merl MY, Saito T, Laé M, Mo Q, Olshen A, Lianoglou S, Leslie C, Ostrovnaya I, Antczak C, Djaballah H, Ladanyi M.
J Pathol. Apr;229(5):743-754. doi: 10.1002/path.4158. Epub 2013 Mar 5 2013
11TFE3
Transcription factor E3, a major regulator of mast cell-mediated allergic response.
Yagil Z, Hadad Erlich T, Ofir-Birin Y, Tshori S, Kay G, Yekhtin Z, Fisher DE, Cheng C, Wong WS, Hartmann K, Razin E, Nechushtan H.
J Allergy Clin Immunol 129(5):1357-1366.e5. doi: 10.1016/j.jaci.2011.11.051. Epub 2012 Feb 22. 2012
12ALK, CLTC, TFE3
Clathrin heavy chain gene fusions expressed in human cancers: analysis of cellular functions.
Blixt MK, Royle SJ.
Traffic 12(6):754-61. doi: 10.1111/j.1600-0854.2011.01183.x. Epub 2011 Mar 24. 2011
13MARK3, MITF, TFE3
C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3.
Schwarz T, Murphy S, Sohn C, Mansky KC.
Biochem Biophys Res Commun 394(4):890-5. Epub 2010 Mar 7.PMID: 20214879 2010
14MAFB, TFE3
TFE3 transcription factor regulates the expression of MAFB during macrophage differentiation.
Zanocco-Marani T, Vignudelli T, Parenti S, Gemelli C, Condorelli F, Martello A, Selmi T, Grande A, Ferrari S.
Exp Cell Res 315(11):1798-808. Epub 2009 Mar 28. 2009
15SREBF1, TFE3
SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling.
Shimano H.
J Mol Med 85(5):437-44. Epub 2007 Feb 6. Review. 2007
16TFE3
Renal cell carcinoma associated with TFE3 gene fusion in an elderly woman.
LaGrange CA, Lele SM, Strup SE.
Urology 70(3):590.e11-2. 2007
17TFE3, IRS2, HK2, INSIG1
TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
Nakagawa Y, Shimano H, Yoshikawa T, Ide T, Tamura M, Furusawa M, Yamamoto T, Inoue N, Matsuzaka T, Takahashi A, Hasty AH, Suzuki H, Sone H, Toyoshima H, Yahagi N, Yamada N.
Nat Med 12(1):107-13. Epub 2005 Dec 4. 2006
18TFE3, TFEB
Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity.
Huan C, Kelly ML, Steele R, Shapira I, Gottesman SR, Roman CA.
Nat Immunol 7(10):1082-91. Epub 2006 Aug 27. 2006
19TFE3, TFEC
Tfe3 expression is closely associated to macrophage terminal differentiation of human hematopoietic myeloid precursors.
Zanocco-Marani T, Vignudelli T, Gemelli C, Pirondi S, Testa A, Montanari M, Parenti S, Tenedini E, Grande A, Ferrari S.
Exp Cell Res 312(20):4079-89. Epub 2006 Sep 22. 2006
20TFE3, TFEB
Renal carcinoma-associated transcription factors TFE3 and TFEB are leukemia inhibitory factor-responsive transcription activators of E-cadherin.
Huan C, Sashital D, Hailemariam T, Kelly ML, Roman CA.
J Biol Chem 280(34):30225-35. Epub 2005 Jun 30. 2005
21TFE3
A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23).
Argani P, Lui MY, Couturier J, Bouvier R, Fournet JC, Ladanyi M.
Oncogene 22(34):5374-8. 2003
22MITF, TFE3, TFEC
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC.
J Leukoc Biol 71(2):304-10. 2002
23ASPS, ASPSCR1, TFE3
The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25.
Ladanyi M, Lui MY, Antonescu CR, Krause-Boehm A, Meindl A, Argani P, Healey JH, Ueda T, Yoshikawa H, Meloni-Ehrig A, Sorensen PH, Mertens F, Mandahl N, van den Berghe H, Sciot R, Cin PD, Bridge J.
Oncogene 20(1):48-57. 2001
24MAD2L2, PRCC, TFE3
Impairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomas.
Weterman MA, van Groningen JJ, Tertoolen L, van Kessel AG.
Proc Natl Acad Sci U S A 98(24):13808-13. 2001
25TFE3
TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional activator of tyrosinase and TyrpI genes.
Verastegui C, Bertolotto C, Bille K, Abbe P, Ortonne JP, Ballotti R.
Mol Endocrinol 14(3):449-56. 2000
26PRCC, TFE3
Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas.
Weterman MAJ, et al.
Proc Natl Acad Sci U S A 93 : 15294-15298. 1996
27PRCC, TFE3
The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene.
Sidhar SK, Clark J, Gill S, Hamoudi R, Crew AJ, Gwilliam R, Ross M, Linehan WM, Birdsall S, Shipley J, Cooper CS.
Hum Mol Genet 5(9):1333-8. 1996
28PRCC, TFE3
Molecular cloning of the papillary renal cell carcinoma-associated translocation (X;1)(p11;q21) breakpoint.
Weterman MA, Wilbrink M, Janssen I, Janssen HA, van den Berg E, Fisher SE, Craig I, Geurts van Kessel A.
Cytogenet Cell Genet 75(1):2-6. 1996
29DXS146, DXS255, TBX1, TBC1D25, SYP, TFE3
Construction of two YAC contigs in human Xp11.23-p11.22, one encompassing the loci OATL1,GATA,TFE3, and SYP, the other linking DXS255 to DXS146.
Fisher SE, et al.
Genomics 29 : 496-502. 1995
30TFE3
The genomic organization of the human transcription factor 3 (TFE3) gene.
Macchi P, et al.
Genomics 28 : 491-494. 1995
31SYP, TFE3
Hybrid and meiotic mapping and construction of a YAC contig in the Xp11 region. (abstr)
Bech-Hansen NT, et al.
Cytogenet Cell Genet 67 : 358. 1994
32TFE3
The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22.
Henthorn PS, et al.
Genomics 11 : 374-378. 1991
33TFE3
A high-frequency RFLP at the human TFE3 locus on the X chromosome.
Puck JM, et al.
Nucleic Acids Res 19 : 684. 1991