1 | TFAP4
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| MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4.
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| Xue C, Yu DM, Gherardi S, Koach J, Milazzo G, Gamble L, Liu B, Valli E, Russell AJ, London WB, Liu T, Cheung BB, Marshall GM, Perini G, Haber M, Norris MD.
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| Oncotarget 7(34):54937-54951. doi: 10.18632/oncotarget.10709.
2016
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2 | BTRC, TFAP4
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| Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division.
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| D'Annibale S, Kim J, Magliozzi R, Low TY, Mohammed S, Heck AJ, Guardavaccaro D.
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| J Biol Chem 289(11):7730-7. doi: 10.1074/jbc.M114.549535. Epub 2014 Feb 5.
2014
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3 | TFAP4
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| AP4 is required for mitogen- and c-MYC-induced cell cycle progression.
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| Jackstadt R, Hermeking H.
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| Oncotarget 5(17):7316-27.
2014
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4 | MYC, TFAP4
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| c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.
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| Chou C, Pinto AK, Curtis JD, Persaud SP, Cella M, Lin CC, Edelson BT, Allen PM, Colonna M, Pearce EL, Diamond MS, Egawa T.
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| Nat Immunol 15(9):884-93. doi: 10.1038/ni.2943. Epub 2014 Jul 13.
2014
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5 | TFAP4
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| AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer.
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| Jackstadt R, Röh S, Neumann J, Jung P, Hoffmann R, Horst D, Berens C, Bornkamm GW, Kirchner T, Menssen A, Hermeking H.
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| J Exp Med 210(7):1331-50. doi: 10.1084/jem.20120812. Epub 2013 Jun 10.
2013
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6 | TFAP4
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| AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation.
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| Jackstadt R, Jung P, Hermeking H.
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| Cell Death Dis 4:e775. doi: 10.1038/cddis.2013.282.
2013
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7 | CREB1, PPP2R2B, SP1, TFAP4
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| The CAG repeat in SCA12 functions as a cis element to up-regulate PPP2R2B expression.
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| Lin CH, Chen CM, Hou YT, Wu YR, Hsieh-Li HM, Su MT, Lee-Chen GJ.
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| Hum Genet 128(2):205-12. doi: 10.1007/s00439-010-0843-2. Epub 2010 Jun 9.
2010
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8 | MYC, TFAP4
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| AP4 encodes a c-MYC-inducible repressor of p21.
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| Jung P, Menssen A, Mayr D, Hermeking H.
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| Proc Natl Acad Sci U S A 105(39):15046-51. Epub 2008 Sep 25.
2008
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9 | DYRK1A, GMNN, TFAP4, STMN2, REST
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| A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells.
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| Kim MY, Jeong BC, Lee JH, Kee HJ, Kook H, Kim NS, Kim YH, Kim JK, Ahn KY, Kim KK.
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| Proc Natl Acad Sci U S A 103(35):13074-9. Epub 2006 Aug 21. 2006
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10 | TFAP4
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| Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis.
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| Tsujimoto K, Ono T, Sato M, Nishida T, Oguma T, Tadakuma T.
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| J Biol Chem 280(30):27638-44. Epub 2005 Jun 8.
2005
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11 | AP4B1, TFAP4, AP4M1
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| AP-4, a novel protein complex related to clathrin adaptors.
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| Dell'Angelica EC, et al.
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| J Biol Chem 274(11):7278-85. 1999
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12 | TFAP4
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| Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.
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| Hu YF, Luscher B, Admon A, Mermod N, Tjian R.
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| Genes Dev 4(10):1741-52. 1990
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