| 1 | TET1
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| Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain
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| Greer CB, Wright J, Weiss JD, Lazarenko RM, Moran SP, Zhu J, Chronister KS, Jin AY, Kennedy AJ, Sweatt JD, Kaas GA.
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| J Neurosci. Jan 27;41(4):578-593. doi: 10.1523/JNEUROSCI.1821-20.2020. Epub 2020 Dec 1. 2021
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| 2 | RNF217, SLC40A1, TET1
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| RNF217 regulates iron homeostasis through its E3 ubiquitin ligase activity by modulating ferroportin degradation
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| Jiang L, Wang J, Wang K, Wang H, Wu Q, Yang C, Yu Y, Ni P, Zhong Y, Song Z, Xie E, Hu R, Min J, Wang F.
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| Blood. Apr 25:blood.2020008986. doi: 10.1182/blood.2020008986. Epub ahead of print. 2021
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| 3 | TET1
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| TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
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| Damal Villivalam S, You D, Kim J, Lim HW, Xiao H, Zushin PH, Oguri Y, Amin P, Kang S.
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| Nat Commun. Aug 27;11(1):4313. doi: 10.1038/s41467-020-18054-y. 2020
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| 4 | TET1
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| Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation. 2020. PMID:
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| Huang G, Liu L, Wang H, Gou M, Gong P, Tian C, Deng W, Yang J, Zhou TT, Xu GL, Liu L.
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| iScience Mar 27;23(3):100908. doi: 10.1016/j.isci.2020.100908. Epub 2020 Feb 13 2020
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| 5 | NANOG, TET1
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| TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues
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| Pantier R, Mullin N, Hall-Ponsele E, Chambers I.
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| J Mol Biol. doi: 1Nov 20;432(23):6075-6091. Epub 2020 Oct 130.1016/j.jmb.2020.10.008 2020
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| 6 | GADD45A, TET1
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| GADD45A binds R-loops and recruits TET1 to CpG island promoters.
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| Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I, Niehrs C.
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| Nat Genet 51(2):217-223. doi: 10.1038/s41588-018-0306-6. Epub 2019 Jan 7.
2019
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| 7 | CXXC5, POU5F1, TET1, TET2
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| Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.
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| Ravichandran M, Lei R, Tang Q, Zhao Y, Lee J, Ma L, Chrysanthou S, Lorton BM, Cvekl A, Shechter D, Zheng D, Dawlaty MM.
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| Cell Rep 28(8):1993-2003.e5. doi: 10.1016/j.celrep.2019.07.080.
2019
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| 8 | EZH2, SIN3A, TET1, TET2
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| Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
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| Cakouros D, Hemming S, Gronthos K, Liu R, Zannettino A, Shi S, Gronthos S.
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| Epigenetics Chromatin. Jan 3;12(1):3. doi: 10.1186/s13072-018-0247-4. 2019
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| 9 | P2RX7, TET1, TET2
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| Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter. 2018
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| Yang R, Yu T, Kou X, Gao X, Chen C, Liu D, Zhou Y, Shi S
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| Nat Commun. Jun 1;9(1):2143. doi: 10.1038/s41467-018-04464-6 2018
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| 10 | RASSF5, TET1
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| TET1 inhibits cell proliferation by inducing RASSF5 expression
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| Li BT, Yu C, Xu Y, Liu SB, Fan HY, Pan WW
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| Oncotarget. Sep 23;8(49):86395-86409. doi: 10.18632/oncotarget.21189 2017
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| 11 | TET1, TET2, ZNF281
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| Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States.
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| Fidalgo M, Huang X, Guallar D, Sanchez-Priego C, Valdes VJ, Saunders A, Ding J, Wu WS, Clavel C, Wang J.
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| Cell Stem Cell 19(3):355-69. doi: 10.1016/j.stem.2016.05.025. Epub 2016 Jun 23. 2016
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| 12 | CECR2, TET1
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| A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.
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| Fong KS, Hufnagel RB, Khadka VS, Corley MJ, Maunakea AK, Fogelgren B, Ahmed ZM, Lozanoff S.
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| Dis Model Mech 9(5):585-96. doi: 10.1242/dmm.024109. Epub 2016 Mar 17.
2016
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| 13 | TET1, TET2, TET3
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| Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.
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| Li X, Yue X, Pastor WA, Lin L, Georges R, Chavez L, Evans SM, Rao A.
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| Proc Natl Acad Sci U S A 113(51):E8267-E8276. doi: 10.1073/pnas.1617802113. Epub 2016 Dec 5.
2016
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| 14 | TET1, TET2
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| Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
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| Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, Yang FC, Jaenisch R, Jin P, Xu M.
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| Cell Rep 13(8):1692-704. doi: 10.1016/j.celrep.2015.10.037. Epub 2015 Nov 12.
2015
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| 15 | PRDM14, TET1, TET2
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| PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.
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| Okashita N, Sakashita N, Ito K, Mitsuya A, Suwa Y, Seki Y.
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| Biochem Biophys Res Commun 466(1):138-45. doi: 10.1016/j.bbrc.2015.08.122. Epub 2015 Aug 29.
2015
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| 16 | GADD45A, TET1
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| GADD45a physically and functionally interacts with TET1.
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| Kienhöfer S, Musheev MU, Stapf U, Helm M, Schomacher L, Niehrs C, Schäfer A.
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| Differentiation 90(1-3):59-68. doi: 10.1016/j.diff.2015.10.003. Epub 2015 Nov 3.
2015
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| 17 | PRDM14, TET1, TET2
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| PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.
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| Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y.
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| Development 141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11.
2014
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| 18 | OGT, TET1
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| Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.
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| Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K, Cuomo A, Roberto A, Christensen J, Bonaldi T, Helin K, Pasini D.
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| Mol Cell 49(4):645-56. doi: 10.1016/j.molcel.2012.12.019. Epub 2013 Jan 24.
2013
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| 19 | RB1, TET1
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| Tet1 is required for Rb phosphorylation during G1/S phase transition.
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| Huang S, Zhu Z, Wang Y, Wang Y, Xu L, Chen X, Xu Q, Zhang Q, Zhao X, Yu Y, Wu D.
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| Biochem Biophys Res Commun. May 3;434(2):241-4. doi: 10.1016/j.bbrc.2013.02.110. Epub 2013 Mar 28. 2013
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| 20 | TET1
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| Tet1 controls meiosis by regulating meiotic gene expression.
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| Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y.
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| Nature 492(7429):443-7. doi: 10.1038/nature11709. Epub 2012 Nov 14.
2012
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| 21 | TET1
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| Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.
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| Guo JU, Su Y, Zhong C, Ming GL, Song H.
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| Cell 145(3):423-34. Epub 2011 Apr 14.
2011
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| 22 | TET1
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| TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
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| Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J, Helin K.
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| Nature 473(7347):343-8. Epub 2011 Apr 13.
2011
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| 23 | TET1
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| Genomic mapping of 5-hydroxymethylcytosine in the human brain.
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| Jin SG, Wu X, Li AX, Pfeifer GP.
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| Nucleic Acids Res 39(12):5015-24. Epub 2011 Mar 4.
2011
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| 24 | TET1, TET2, TET3
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| Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond.
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| Guo JU, Su Y, Zhong C, Ming GL, Song H.
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| Cell Cycle 10(16):2662-8. Epub 2011 Aug 15. Review.
2011
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| 25 | NANOG, TET1
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| Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
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| Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y.
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| Nature 466(7310):1129-33. 2010
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| 26 | TET1, TET2, TET3
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| Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
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| Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, Huberman K, Thomas S, Dolgalev I, Heguy A, Paietta E, Le Beau MM, Beran M, Tallman MS, Ebert BL, Kantarjian HM, Stone RM, Gilliland DG, Crispino JD, Levine RL.
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| Blood 114(1):144-7. Epub 2009 May 6.
2009
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| 27 | ANK3, CTNNA3, TET1
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| Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.
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| Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, Lovestone S, Williams J, Owen MJ.
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| Am J Med Genet B Neuropsychiatr Genet 147B(6):727-31.
2008
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| 28 | AGAP10, AGAP6, AGAP7, AGAP8, AKR1CL1, ALDH18A1, ANXA8L1, BTBD16, C10orf103, C10orf108, C10orf111, C10orf113, C10orf114, C10orf115, C10orf120, C10orf122, C10orf25, C10orf26, C10orf30, C10orf32, C10orf35, C10orf47, C10orf55, C10orf67, C10orf71, CACUL1, CALHM1, CH25H, EBF3, FAM22D, FAM23A, FAM23B, FAM24A, FAM25A, FAM25B, FAM25C, FAM25D, FAM25E, FAM25G, FAM25HP, FZD8, GPAM, HECTD2, HOGA1, PDE6C, SYNPO2L, TET1, UTF1, VAX1, XPNPEP1, YME1L1, ZCCHC24, ZNF511
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| The DNA sequence and comparative analysis of human chromosome 10.
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| Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L, Steward CA, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE, Andrews TD, Gilbert JG, Swarbreck D, Ashurst JL, Taylor A, Battles J, Bird CP, Ainscough R, Almeida JP, Ashwell RI, Ambrose KD, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H, Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Cahill P, Camire D, Carter NP, Chapman JC, Clark SY, Clarke G, Clee CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S, Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E, Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C, Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK, Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE, McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou T, Sehra HK, Shownkeen R, Skuce CD, Smith M, Standring L, Sycamore N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J, Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK, Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T, Doucette-Stamm L, Beck S, Smith DR, Rogers J.
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| Nature 429(6990):375-81. 2004
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| 29 | TET1, TET2
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| TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).
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| Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing JR.
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| Leukemia 17(3):637-41. No abstract available. 2003
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| 30 | KMT2A, TET1
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| LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).
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| Ono R, Taki T, Taketani T, Taniwaki M, Kobayashi H, Hayashi Y.
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| Cancer Res 62(14):4075-80. 2002
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| 31 | ACAP3, AMBRA1, CMIP, CNTNAP3, CNTNAP4, CPEB4, DAB2IP, DDHD1, DISP2, EEPD1, EXOC4, FAM40A, HELZ2, ITPRIP, KIAA1683, KIAA1712, KIAA1715, KIAA1737, KIAA1751, KIAA1755, KIF21A, MTMR12, PHACTR1, PHF21A, PRDM16, RAPH1, RHOXF1, SEMA4B, SEMA4C, SET7, SH3BP5L, SPHKAP, SSH2, TET1, TEX2, TNKS1BP1, UBE2O, UNC13A, UNK, WNK2, ZCCHC2, ZFHX2, ZNF407, ZNF436
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| Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O.
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| DNA Res 7(6):347-55. 2000
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