| 1 | TDP1, TOP2A
|
| Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells.
|
| Borda MA, Palmitelli M, Verón G, González-Cid M, de Campos Nebel M.
|
| Mutat Res 781:37-48. doi: 10.1016/j.mrfmmm.2015.09.003. Epub 2015 Sep 14.
2015
|
| 2 | TDP1
|
| TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.
|
| Heo J, Li J, Summerlin M, Hays A, Katyal S, McKinnon PJ, Nitiss KC, Nitiss JL, Hanakahi LA.
|
| DNA Repair (Amst) 30:28-37. doi: 10.1016/j.dnarep.2015.03.003. Epub 2015 Mar 17.
2015
|
| 3 | TDP1
|
| Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage.
|
| Comeaux EQ, Cuya SM, Kojima K, Jafari N, Wanzeck KC, Mobley JA, Bjornsti MA, van Waardenburg RC.
|
| J Biol Chem 290(10):6203-14. doi: 10.1074/jbc.M114.635284. Epub 2015 Jan 21.
2015
|
| 4 | TDP1
|
| TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy.
|
| Alagoz M, Wells OS, El-Khamisy SF.
|
| Nucleic Acids Res 42(5):3089-103. doi: 10.1093/nar/gkt1260. Epub 2013 Dec 13.
2014
|
| 5 | APTX, TDP1
|
| The role of TDP1 and APTX in mitochondrial DNA repair.
|
| Meagher M, Lightowlers RN.
|
| Biochimie 100:121-4. doi: 10.1016/j.biochi.2013.10.011. Epub 2013 Oct 22. Review.
2014
|
| 6 | APTX, TDP1
|
| The role of TDP1 and APTX in mitochondrial DNA repair.
|
| Meagher M, Lightowlers RN.
|
| Biochimie 100:121-4. doi: 10.1016/j.biochi.2013.10.011. Epub 2013 Oct 22. Review.
2014
|
| 7 | TDP1, TDP2, TOP1, TOP1MT
|
| Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).
|
| Pommier Y, Huang SY, Gao R, Das BB, Murai J, Marchand C.
|
| DNA Repair (Amst) 19:114-29. doi: 10.1016/j.dnarep.2014.03.020. Epub 2014 May 22. Review.
2014
|
| 8 | TDP1
|
| Association of tyrosyl-DNA phosphodiesterase 1 polymorphism with Tourette syndrome in Taiwanese patients.
|
| Wu BT, Lin WY, Chou IC, Liu HP, Lee CC, Tsai Y, Wu WC, Tsai FJ.
|
| J Clin Lab Anal 27(4):323-7. doi: 10.1002/jcla.21606.
2013
|
| 9 | TDP1, sCAN1
|
| Expression profile and mitochondrial colocalization of Tdp1 in peripheral human tissues.
|
| Fam HK, Chowdhury MK, Walton C, Choi K, Boerkoel CF, Hendson G.
|
| J Mol Histol 44(4):481-94. doi: 10.1007/s10735-013-9496-5. Epub 2013 Mar 28.
2013
|
| 10 | TDP1, TDP2
|
| TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
|
| Zeng Z, Sharma A, Ju L, Murai J, Umans L, Vermeire L, Pommier Y, Takeda S, Huylebroeck D, Caldecott KW, El-Khamisy SF.
|
| Nucleic Acids Res 40(17):8371-80. Epub 2012 Jun 26.
2012
|
| 11 | TDP1
|
| SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.
|
| Hudson JJ, Chiang SC, Wells OS, Rookyard C, El-Khamisy SF.
|
| Nat Commun 3:733. doi: 10.1038/ncomms1739.
2012
|
| 12 | TDP1, TOP1
|
| Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells.
|
| Hubert L Jr, Lin Y, Dion V, Wilson JH.
|
| Mol Cell Biol 31(15):3105-12. doi: 10.1128/MCB.05158-11. Epub 2011 May 31.
2011
|
| 13 | TDP1
|
| Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.
|
| Das BB, Dexheimer TS, Maddali K, Pommier Y.
|
| Proc Natl Acad Sci U S A 107(46):19790-5. Epub 2010 Nov 1.
2010
|
| 14 | TDP1
|
| Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks.
|
| Zhou T, Akopiants K, Mohapatra S, Lin PS, Valerie K, Ramsden DA, Lees-Miller SP, Povirk LF.
|
| DNA Repair (Amst) 8(8):901-11. Epub 2009 Jun 7.PMID: 19505854 2009
|
| 15 | ATM, PRKDC, TDP1
|
| Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK.
|
| Das BB, Antony S, Gupta S, Dexheimer TS, Redon CE, Garfield S, Shiloh Y, Pommier Y.
|
| EMBO J 28(23):3667-80. Epub 2009 Oct 22.PMID: 19851285 2009
|
| 16 | TDP1, SCAN1
|
| TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.
|
| Katyal S, el-Khamisy SF, Russell HR, Li Y, Ju L, Caldecott KW, McKinnon PJ.
|
| EMBO J 26(22):4720-31. Epub 2007 Oct 4. 2007
|
| 17 | SCAN1, TDP1
|
| Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
|
| Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF.
|
| EMBO J 26(22):4732-43. Epub 2007 Oct 18. 2007
|
| 18 | TDP1, SCAN1
|
| Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1.
|
| El-Khamisy SF, Saifi GM, Weinfeld M, Johansson F, Helleday T, Lupski JR, Caldecott KW.
|
| Nature 434(7029):108-13. 2005
|
| 19 | TDP1
|
| TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II.
|
| Barthelmes HU, Habermeyer M, Christensen MO, Mielke C, Interthal H, Pouliot JJ, Boege F, Marko D.
|
| J Biol Chem 279(53):55618-25. Epub 2004 Oct 19. 2004
|
| 20 | AOA1, APTX, SCAN1, TDP1
|
| DNA single-strand break repair and spinocerebellar ataxia.
|
| Caldecott KW.
|
| Cell 112(1):7-10. Review. 2003
|
| 21 | TDP1, SCAN1
|
| Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy.
|
| Takashima H, Boerkoel CF, John J, Saifi GM, Salih MA, Armstrong D, Mao Y, Quiocho FA, Roa BB, Nakagawa M, Stockton DW, Lupski JR.
|
| Nat Genet 32(2):267-72. Epub 2002 Sep 16. 2002
|
| 22 | TDP1
|
| The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase Dsuperfamily.
|
| Interthal H, Pouliot JJ, Champoux JJ.
|
| Proc Natl Acad Sci U S A 98(21):12009-14. 2001
|
| 23 | TDP1
|
| Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase Icomplexes.
|
| Pouliot JJ, Yao KC, Robertson CA, Nash HA.
|
| Science 286(5439):552-5. 1999
|