Citations for
1MEF2C, TDGF1
MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.
Barnes RM, Harris IS, Jaehnig EJ, Sauls K, Sinha T, Rojas A, Schachterle W, McCulley DJ, Norris RA, Black BL.
Development 143(5):774-9. doi: 10.1242/dev.126383. 2016
2TDGF1
Cripto-1 modulates macrophage cytokine secretion and phagocytic activity via NF-κB signaling.
Zhang DM, Bao YL, Yu CL, Wang YM, Song ZB.
Immunol Res 64(1):104-14. 2016
3NODAL, TDGF1
New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding.
FocÓ A, Sanguigno L, FocÓ G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A.
Int J Mol Sci 16(9):21342-62. doi: 10.3390/ijms160921342. 2015
4TDGF1
Cripto-1: an extracellular protein - connecting the sequestered biological dots.
Klauzinska M, Bertolette D, Tippireddy S, Strizzi L, Gray PC, Gonzales M, Duroux M, Ruvo M, Wechselberger C, Castro NP, Rangel MC, FocÓ A, Sandomenico A, Hendrix MJ, Salomon D, Cuttitta F.
Connect Tissue Res 56(5):364-80. doi: 10.3109/03008207.2015.1077239. 2015
5SNAI1, TDGF1
Snail-mediated Cripto-1 repression regulates the cell cycle and epithelial-mesenchymal transition-related gene expression.
Pilli VS, Gupta K, Kotha BP, Aradhyam GK.
FEBS Lett 589(11):1249-56. doi: 10.1016/j.febslet.2015.04.005. 2015
6TDGF1
CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities.
Terry S, El-Sayed IY, Destouches D, MaillÚ P, Nicolaiew N, Ploussard G, Semprez F, Pimpie C, Beltran H, Londono-Vallejo A, Allory Y, de la Taille A, Salomon DS, Vacherot F.
Oncotarget 6(14):11994-2008. 2015
7TDGF1
The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition.
Klauzinska M, Castro NP, Rangel MC, Spike BT, Gray PC, Bertolette D, Cuttitta F, Salomon D.
Semin Cancer Biol 29:51-8. doi: 10.1016/j.semcancer.2014.08.003. Review. 2014
8HSPA5, TDGF1
CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.
Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC.
Stem Cell Reports 2(4):427-39. doi: 10.1016/j.stemcr.2014.02.010. 2014
9NODAL, TDGF1
TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.
Boerner BP, George NM, Targy NM, Sarvetnick NE.
Endocrinology 154(11):4099-112. doi: 10.1210/en.2013-1197. 2013
10TDGF1
Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.
Jin JZ, Ding J.
Dev Biol 381(1):170-8. doi: 10.1016/j.ydbio.2013.05.029. 2013
11TDGF1
Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
Nagaoka T, Karasawa H, Turbyville T, Rangel MC, Castro NP, Gonzales M, Baker A, Seno M, Lockett S, Greer YE, Rubin JS, Salomon DS, Bianco C.
Cell Signal 25(1):178-89. doi: 10.1016/j.cellsig.2012.09.024. 2013
12TDGF1
Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.
McKean DM, Niswander L.
Biol Open 1(9):874-83. doi: 10.1242/bio.20121982. 2012
13MSTN, TDGF1
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.
Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, BouchÚ A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G.
Proc Natl Acad Sci U S A 109(47):E3231-40. doi: 10.1073/pnas.1204017109. 2012
14TDGF1
Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.
Rangel MC, Karasawa H, Castro NP, Nagaoka T, Salomon DS, Bianco C.
Am J Pathol 180(6):2188-200. doi: 10.1016/j.ajpath.2012.02.031. Review. 2012
15NODAL, TDGF1
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.
Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J.
Development 139(22):4123-32. doi: 10.1242/dev.083006. Epub 2012 Oct 3. 2012
16NODAL, TDGF1
Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.
Kruithof-de Julio M, Alvarez MJ, Galli A, Chu J, Price SM, Califano A, Shen MM.
Development 138(18):3885-95. doi: 10.1242/dev.065656. 2011
17TDGF1
The role of Cripto-1 in the tumorigenesis and progression of oral squamous cell carcinoma.
Yoon HJ, Hong JS, Shin WJ, Lee YJ, Hong KO, Lee JI, Hong SP, Hong SD.
Oral Oncol 47(11):1023-31. doi: 10.1016/j.oraloncology.2011.07.019. 2011
18CFC1, TDGF1
Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.
Chu J, Shen MM.
Dev Biol 342(1):63-73. doi: 10.1016/j.ydbio.2010.03.009. 2010
19HSPA5, TDGF1
Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.
Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC.
Oncogene 28(24):2324-36. Epub 2009 May 4. 2009
20NODAL, GDF1, TDGF1, FOXH1
Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly.
Roessler E, Ouspenskaia MV, Karkera JD, VÄlez JI, Kantipong A, Lacbawan F, Bowers P, Belmont JW, Towbin JA, Goldmuntz E, Feldman B, Muenke M.
Am J Hum Genet 83(1):18-29. Epub 2008 Jun 5. 2008
21TDGF1, TDGF3
CRIPTO3, a presumed pseudogene, is expressed in cancer.
Sun C, Orozco O, Olson DL, Choi E, Garber E, Tizard R, Szak S, Sanicola M, Carulli JP.
Biochem Biophys Res Commun 377(1):215-20. Epub 2008 Oct 1. 2008
22NODAL, TDGF1
Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway.
Bianco C, Mysliwiec M, Watanabe K, Mancino M, Nagaoka T, Gonzales M, Salomon DS.
FEBS Lett 582(29):3997-4002. Epub 2008 Nov 18. 2008
23NODAL, TDGF1
Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal.
Kelber JA, Shani G, Booker EC, Vale WW, Gray PC.
J Biol Chem 283(8):4490-500. Epub 2007 Dec 18. 2008
24HSPA5, TDGF1
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
Mol Cell Biol 28(2):666-77. Epub 2007 Nov 8.PMID: 17991893 2008
25TDGF1
Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Mancino M, Strizzi L, Wechselberger C, Watanabe K, Gonzales M, Hamada S, Normanno N, Salomon DS, Bianco C.
J Cell Physiol 215(1):192-203.PMID: 17941089 2008
26CFC1, HSPA5, TDGF1
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
Mol Cell Biol 28(2):666-77. 2008
27TDGF1, LEF1
beta-Catenin/TCF/LEF regulate expression of the short form human Cripto-1.
Hamada S, Watanabe K, Hirota M, Bianco C, Strizzi L, Mancino M, Gonzales M, Salomon DS.
Biochem Biophys Res Commun 355(1):240-4. Epub 2007 Feb 2. 2007
28TDGF1
Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS.
J Biol Chem 282(43):31643-55. Epub 2007 Aug 24. 2007
29NR6A1, TDGF1, TDGF3
Germ cell nuclear factor is a repressor of CRIPTO-1 and CRIPTO-3.
Hentschke M, Kurth I, Borgmeyer U, H´┐Żbner CA.
J Biol Chem 281(44):33497-504. Epub 2006 Sep 5. 2006
30TDGF1
Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis.
Strizzi L, Bianco C, Normanno N, Salomon D.
Oncogene 24(37):5731-41. Review. 2005
31HPEL1, TDGF1
A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
De La Cruz JM, Bamford RN, Burdine RD, Roessler E, Barkovich AJ, Donnai D, Schier AF, Muenke M.
Hum Genet 110(5):422-8. 2002
32NODAL, TDGF1
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.
Yan YT, Liu JJ, Luo Y, E C, Haltiwanger RS, Abate-Shen C, Shen MM.
Mol Cell Biol 22(13):4439-49. 2002
33TDGF1, TDGF1P2, TDGF1P3, TDGF1P4, TDGF1P5, TDGF1P6, TDGF1P7
Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1.
Scognamiglio B, et al.
Cytogenet Cell Genet 84(3-4):220-224. 1999
34TDGF1
Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo.
Ding J, Yang L, Yan YT, Chen A, Desai N, Wynshaw-Boris A, Shen MM.
Nature 395(6703):702-7. 1998
35TDGF1
Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
Kannan S, et al.
J Biol Chem 272 : 3330-3335. 1997
36TDGF1
Regional localization of the human EGF-like growth factor CRIPTO gene (TDGF-1) to chromosome 3p21.
Saccone S, et al.
Hum Genet 95 : 229-230. 1995
37TDGF1, TDGF3
Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence.
Dono R, et al.
Am J Hum Genet 49 : 555-565. 1991
38TDGF1
Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells.
Ciccodicola A, Dono R, Obici S, Simeone A, Zollo M, Persico MG.
EMBO J 8(7):1987-91. 1989