| 1 | MEF2C, TDGF1
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| MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.
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| Barnes RM, Harris IS, Jaehnig EJ, Sauls K, Sinha T, Rojas A, Schachterle W, McCulley DJ, Norris RA, Black BL.
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| Development 143(5):774-9. doi: 10.1242/dev.126383.
2016
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| 2 | TDGF1
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| Cripto-1 modulates macrophage cytokine secretion and phagocytic activity via NF-κB signaling.
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| Zhang DM, Bao YL, Yu CL, Wang YM, Song ZB.
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| Immunol Res 64(1):104-14.
2016
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| 3 | NODAL, TDGF1
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| New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding.
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| Focà A, Sanguigno L, Focà G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A.
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| Int J Mol Sci 16(9):21342-62. doi: 10.3390/ijms160921342.
2015
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| 4 | TDGF1
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| Cripto-1: an extracellular protein - connecting the sequestered biological dots.
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| Klauzinska M, Bertolette D, Tippireddy S, Strizzi L, Gray PC, Gonzales M, Duroux M, Ruvo M, Wechselberger C, Castro NP, Rangel MC, Focà A, Sandomenico A, Hendrix MJ, Salomon D, Cuttitta F.
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| Connect Tissue Res 56(5):364-80. doi: 10.3109/03008207.2015.1077239.
2015
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| 5 | SNAI1, TDGF1
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| Snail-mediated Cripto-1 repression regulates the cell cycle and epithelial-mesenchymal transition-related gene expression.
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| Pilli VS, Gupta K, Kotha BP, Aradhyam GK.
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| FEBS Lett 589(11):1249-56. doi: 10.1016/j.febslet.2015.04.005.
2015
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| 6 | TDGF1
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| CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities.
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| Terry S, El-Sayed IY, Destouches D, Maillé P, Nicolaiew N, Ploussard G, Semprez F, Pimpie C, Beltran H, Londono-Vallejo A, Allory Y, de la Taille A, Salomon DS, Vacherot F.
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| Oncotarget 6(14):11994-2008.
2015
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| 7 | TDGF1
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| The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition.
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| Klauzinska M, Castro NP, Rangel MC, Spike BT, Gray PC, Bertolette D, Cuttitta F, Salomon D.
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| Semin Cancer Biol 29:51-8. doi: 10.1016/j.semcancer.2014.08.003. Review.
2014
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| 8 | HSPA5, TDGF1
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| CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.
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| Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC.
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| Stem Cell Reports 2(4):427-39. doi: 10.1016/j.stemcr.2014.02.010.
2014
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| 9 | NPTX1, TDGF1
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| NPTX1 regulates neural lineage specification from human pluripotent stem cells.
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| Boles NC, Hirsch SE, Le S, Corneo B, Najm F, Minotti AP, Wang Q, Lotz S, Tesar PJ, Fasano CA.
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| Cell Rep. Feb 27;6(4):724-36. doi: 10.1016/j.celrep.2014.01.026. Epub 2014 Feb 13 2014
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| 10 | NODAL, TDGF1
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| TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.
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| Boerner BP, George NM, Targy NM, Sarvetnick NE.
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| Endocrinology 154(11):4099-112. doi: 10.1210/en.2013-1197.
2013
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| 11 | TDGF1
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| Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.
|
| Jin JZ, Ding J.
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| Dev Biol 381(1):170-8. doi: 10.1016/j.ydbio.2013.05.029.
2013
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| 12 | TDGF1
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| Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
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| Nagaoka T, Karasawa H, Turbyville T, Rangel MC, Castro NP, Gonzales M, Baker A, Seno M, Lockett S, Greer YE, Rubin JS, Salomon DS, Bianco C.
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| Cell Signal 25(1):178-89. doi: 10.1016/j.cellsig.2012.09.024.
2013
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| 13 | TDGF1
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| Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.
|
| McKean DM, Niswander L.
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| Biol Open 1(9):874-83. doi: 10.1242/bio.20121982.
2012
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| 14 | MSTN, TDGF1
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| Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.
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| Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, Bouché A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G.
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| Proc Natl Acad Sci U S A 109(47):E3231-40. doi: 10.1073/pnas.1204017109. 2012
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| 15 | TDGF1
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| Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.
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| Rangel MC, Karasawa H, Castro NP, Nagaoka T, Salomon DS, Bianco C.
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| Am J Pathol 180(6):2188-200. doi: 10.1016/j.ajpath.2012.02.031. Review.
2012
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| 16 | NODAL, TDGF1
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| Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.
|
| Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J.
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| Development 139(22):4123-32. doi: 10.1242/dev.083006. Epub 2012 Oct 3.
2012
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| 17 | NODAL, TDGF1
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| Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.
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| Kruithof-de Julio M, Alvarez MJ, Galli A, Chu J, Price SM, Califano A, Shen MM.
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| Development 138(18):3885-95. doi: 10.1242/dev.065656.
2011
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| 18 | TDGF1
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| The role of Cripto-1 in the tumorigenesis and progression of oral squamous cell carcinoma.
|
| Yoon HJ, Hong JS, Shin WJ, Lee YJ, Hong KO, Lee JI, Hong SP, Hong SD.
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| Oral Oncol 47(11):1023-31. doi: 10.1016/j.oraloncology.2011.07.019.
2011
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| 19 | CFC1, TDGF1
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| Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.
|
| Chu J, Shen MM.
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| Dev Biol 342(1):63-73. doi: 10.1016/j.ydbio.2010.03.009.
2010
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| 20 | HSPA5, TDGF1
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| Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.
|
| Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC.
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| Oncogene 28(24):2324-36. Epub 2009 May 4.
2009
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| 21 | NODAL, GDF1, TDGF1, FOXH1
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| Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly.
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| Roessler E, Ouspenskaia MV, Karkera JD, VŽlez JI, Kantipong A, Lacbawan F, Bowers P, Belmont JW, Towbin JA, Goldmuntz E, Feldman B, Muenke M.
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| Am J Hum Genet 83(1):18-29. Epub 2008 Jun 5. 2008
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| 22 | TDGF1, TDGF3
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| CRIPTO3, a presumed pseudogene, is expressed in cancer.
|
| Sun C, Orozco O, Olson DL, Choi E, Garber E, Tizard R, Szak S, Sanicola M, Carulli JP.
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| Biochem Biophys Res Commun 377(1):215-20. Epub 2008 Oct 1.
2008
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| 23 | NODAL, TDGF1
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| Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway.
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| Bianco C, Mysliwiec M, Watanabe K, Mancino M, Nagaoka T, Gonzales M, Salomon DS.
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| FEBS Lett 582(29):3997-4002. Epub 2008 Nov 18.
2008
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| 24 | NODAL, TDGF1
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| Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal.
|
| Kelber JA, Shani G, Booker EC, Vale WW, Gray PC.
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| J Biol Chem 283(8):4490-500. Epub 2007 Dec 18.
2008
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| 25 | HSPA5, TDGF1
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| GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
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| Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
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| Mol Cell Biol 28(2):666-77. Epub 2007 Nov 8.PMID: 17991893 2008
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| 26 | TDGF1
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| Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
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| Mancino M, Strizzi L, Wechselberger C, Watanabe K, Gonzales M, Hamada S, Normanno N, Salomon DS, Bianco C.
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| J Cell Physiol 215(1):192-203.PMID: 17941089 2008
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| 27 | CFC1, HSPA5, TDGF1
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| GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
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| Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
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| Mol Cell Biol 28(2):666-77.
2008
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| 28 | TDGF1, LEF1
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| beta-Catenin/TCF/LEF regulate expression of the short form human Cripto-1.
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| Hamada S, Watanabe K, Hirota M, Bianco C, Strizzi L, Mancino M, Gonzales M, Salomon DS.
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| Biochem Biophys Res Commun 355(1):240-4. Epub 2007 Feb 2. 2007
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| 29 | TDGF1
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| Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
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| Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS.
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| J Biol Chem 282(43):31643-55. Epub 2007 Aug 24. 2007
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| 30 | NR6A1, TDGF1, TDGF3
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| Germ cell nuclear factor is a repressor of CRIPTO-1 and CRIPTO-3.
|
| Hentschke M, Kurth I, Borgmeyer U, H�bner CA.
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| J Biol Chem 281(44):33497-504. Epub 2006 Sep 5. 2006
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| 31 | TDGF1
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| Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis.
|
| Strizzi L, Bianco C, Normanno N, Salomon D.
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| Oncogene 24(37):5731-41. Review. 2005
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| 32 | HPEL1, TDGF1
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| A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
|
| De La Cruz JM, Bamford RN, Burdine RD, Roessler E, Barkovich AJ, Donnai D, Schier AF, Muenke M.
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| Hum Genet 110(5):422-8. 2002
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| 33 | NODAL, TDGF1
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| Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.
|
| Yan YT, Liu JJ, Luo Y, E C, Haltiwanger RS, Abate-Shen C, Shen MM.
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| Mol Cell Biol 22(13):4439-49. 2002
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| 34 | TDGF1, TDGF1P2, TDGF1P3, TDGF1P4, TDGF1P5, TDGF1P6, TDGF1P7
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| Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1.
|
| Scognamiglio B, et al.
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| Cytogenet Cell Genet 84(3-4):220-224. 1999
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| 35 | TDGF1
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| Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo.
|
| Ding J, Yang L, Yan YT, Chen A, Desai N, Wynshaw-Boris A, Shen MM.
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| Nature 395(6703):702-7. 1998
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| 36 | TDGF1
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| Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
|
| Kannan S, et al.
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| J Biol Chem 272 : 3330-3335. 1997
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| 37 | TDGF1
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| Regional localization of the human EGF-like growth factor CRIPTO gene (TDGF-1) to chromosome 3p21.
|
| Saccone S, et al.
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| Hum Genet 95 : 229-230. 1995
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| 38 | TDGF1, TDGF3
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| Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence.
|
| Dono R, et al.
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| Am J Hum Genet 49 : 555-565. 1991
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| 39 | TDGF1
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| Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells.
|
| Ciccodicola A, Dono R, Obici S, Simeone A, Zollo M, Persico MG.
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| EMBO J 8(7):1987-91. 1989
|