| 1 | TAF6, TAF9, TBP, TCP1
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| Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.
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| Antonova SV, Haffke M, Corradini E, Mikuciunas M, Low TY, Signor L, van Es RM, Gupta K, Scheer E, Vos HR, Tora L, Heck AJR, Timmers HTM, Berger I.
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| Nat Struct Mol Biol. Dec;25(12):1119-1127. doi: 10.1038/s41594-018-0156-z. Epub 2018 Dec 3 2018
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| 2 | DCAF7, TCP1
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| The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation.
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| Miyata Y, Shibata T, Aoshima M, Tsubata T, Nishida E.
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| J Biol Chem 289(48):33320-32. doi: 10.1074/jbc.M114.586115. Epub 2014 Oct 22.
2014
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| 3 | PDCL, TCP1
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| Splice isoforms of phosducin-like protein control the expression of heterotrimeric G proteins.
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| Gao X, Sinha S, Belcastro M, Woodard C, Ramamurthy V, Stoilov P, Sokolov M.
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| J Biol Chem 288(36):25760-8. doi: 10.1074/jbc.M113.486258. Epub 2013 Jul 25.
2013
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| 4 | TCP1
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| Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae.
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| Redgrove KA, Anderson AL, Dun MD, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B.
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| Dev Biol 356(2):460-74. Epub 2011 Jun 13.
2011
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| 5 | TCP1
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| Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival.
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| Posokhova E, Song H, Belcastro M, Higgins L, Bigley LR, Michaud NA, Martemyanov KA, Sokolov M.
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| Mol Cell Proteomics 10(1):M110.000570. Epub 2010 Sep 17.
2011
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| 6 | TCP1
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| Equivalent mutations in the eight subunits of the chaperonin CCT produce dramatically different cellular and gene expression phenotypes.
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| Amit M, Weisberg SJ, Nadler-Holly M, McCormack EA, Feldmesser E, Kaganovich D, Willison KR, Horovitz A.
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| J Mol Biol 401(3):532-43. Epub 2010 Jun 25.
2010
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| 7 | CCT2, CCT3, CCT4, CCT5, CCT6A, CCT7, CCT8, TCP1
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| The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.
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| Zebol JR, Hewitt NM, Moretti PA, Lynn HE, Lake JA, Li P, Vadas MA, Wattenberg BW, Pitson SM.
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| Int J Biochem Cell Biol 41(4):822-7. Epub 2008 Aug 14.PMID: 18775504 2009
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| 8 | CCT5, TCP1
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| The role of molecular chaperones in human misfolding diseases.
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| Broadley SA, Hartl FU.
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| FEBS Lett 583(16):2647-53. Epub 2009 Apr 23. Review.PMID: 19393652 2009
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| 9 | HSPA8, TCP1
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| The structure of CCT-Hsc70 NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin.
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| Cuéllar J, Martín-Benito J, Scheres SH, Sousa R, Moro F, López-Viñas E, Gómez-Puertas P, Muga A, Carrascosa JL, Valpuesta JM.
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| Nat Struct Mol Biol 15(8):858-64. Epub 2008 Jul 27.
2008
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| 10 | TCP1
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| Domain-specific chaperone-induced expansion is required for beta-actin folding: a comparison of beta-actin conformations upon interactions with GroEL and tail-less complex polypeptide 1 ring complex (TRiC).
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| Villebeck L, Moparthi SB, Lindgren M, Hammarstršm P, Jonsson BH.
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| Biochemistry 46(44):12639-47. Epub 2007 Oct 16. 2007
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| 11 | PDCL2, TCP1
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| Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression.
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| Stirling PC, Srayko M, Takhar KS, Pozniakovsky A, Hyman AA, Leroux MR.
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| Mol Biol Cell 18(6):2336-45. Epub 2007 Apr 11. 2007
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| 12 | AHCYL2, HDAC4, RPS6KA6, TCP1
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| New p53 related genes in human tumors: significant downregulation in colon and lung carcinomas.
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| LLeonart ME, Vidal F, Gallardo D, Diaz-Fuertes M, Rojo F, Cuatrecasas M, López-Vicente L, Kondoh H, Blanco C, Carnero A, Ramón y Cajal S.
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| Oncol Rep 16(3):603-8.
2006
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| 13 | PLK1, TCP1
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| CCT chaperonin complex is required for the biogenesis of functional Plk1.
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| Liu X, Lin CY, Lei M, Yan S, Zhou T, Erikson RL.
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| Mol Cell Biol 25(12):4993-5010. 2005
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| 14 | TCP1
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| The CCT chaperonin promotes activation of the anaphase-promoting complex through the generation of functional Cdc20.
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| Camasses A, Bogdanova A, Shevchenko A, Zachariae W.
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| Mol Cell 12(1):87-100. 2003
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| 15 | TCP1
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| Slow axonal transport of the cytosolic chaperonin CCT with Hsc73 and actin in motor neurons.
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| Bourke GJ, El Alami W, Wilson SJ, Yuan A, Roobol A, Carden MJ.
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| J Neurosci Res 68(1):29-35. 2002
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| 16 | TCP1
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| Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease.
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| Schuller E, Gulesserian T, Seidl R, Cairns N, Lube G.
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| Life Sci 69(3):263-70. 2001
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| 17 | CCT2, CCT3, CCT4, TCP1, CCT5, CCT6A, CCT6B, CCT7, CCT8
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| Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle.
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| Yokota S, Yanagi H, Yura T, Kubota H.
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| Eur J Biochem 268(17):4664-73. 2001
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| 18 | ACAT2, TCP1
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| Origin of gene overlap: the case of TCP1 and ACAT2.
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| Shintani S, et al.
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| Genetics 152(2):743-54. 1999
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| 19 | TCP1
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| Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits.
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| Frydman J, Nimmesgern E, Erdjument-Bromage H, Wall JS, Tempst P, Hartl FU.
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| EMBO J 11(13):4767-78 1992
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| 20 | TCP1, TCP10
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| Three loci homologous with murine t complex genes are localized in a 4 point linkage group on the long arm of chromosome 6 (6q).
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| BlanchŽ H, et al.
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| (HGM10) Cytogenet Cell Genet 51 : 963. 1989
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| 21 | TCP1, D6S46
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| Human homologs of two testes-expressed loci on mouse chromosome 17 map to opposite arms of chromosome 6.
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| Bibbins KB, et al.
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| Genomics 5 : 139-143. 1989
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| 22 | TCP1
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| Assignment of the TCP-1 locus to the long arm of human chromosome 6 by in situ hybridization.
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| Fonatsch C, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 615. 1987
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| 23 | TCP1
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| Localization to human chromosome 6 of a human DNA segment homologous to a genomic sequence from the distal portion of the mouse T/t complex.
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| Cohen-Haguenauer O, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 595. 1987
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| 24 | TCP1, TCP1P1, TCP1P2
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| The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region.
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| Willison K, et al.
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| EMBO J 6 : 1967-1974. 1987
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| 25 | TCP1
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| TCP1 is not linked to HLA, GLO1, PGK1P2 and other markers in a 45cM map of the short arm of chromosome 6 (6p).
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| BlanchŽ H, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 581. 1987
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| 26 | TCP1
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| Assignment of TCP1 locus to the long arm of human chromosome 6 by in situ hybridization.
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| Fonatsch C, et al.
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| Cytogenet Cell Genet 45 : 109-112. 1987
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| 27 | TCP1
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| Chromosomal assignment of TCP-1 the human homologue of a mouse t-complex locus.
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| Willison K, et al.
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| (HGM8) Cytogenet Cell Genet 40: 779-780. 1985
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