| 1 | MYOCD, SRF, TCF21
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| Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway.
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| Nagao M, Lyu Q, Zhao Q, Wirka RC, Bagga J, Nguyen T, Cheng P, Kim JB, Pjanic M, Miano JM, Quertermous T.
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| Circ Res. Feb 14;126(4):517-529. doi: 10.1161/CIRCRESAHA.119.315968. Epub 2019 Dec 9 2020
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| 2 | LPL, TCF21
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| A Novel Regulator of Preadipocyte Differentiation, Transcription Factor TCF21, Functions Partially Through Promoting LPL Expression.
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| Zhang X, Cheng B, Liu C, Du Z, Zhang H, Wang N, Wu M, Li Y, Cao Z, Li H.
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| Front Physiol. Apr 23;10:458. doi: 10.3389/fphys.2019.00458. eCollection 2019 2019
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| 3 | TCF21
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| TCF21 inhibits tumor-associated angiogenesis and suppresses the growth of cholangiocarcinoma by targeting PI3K/Akt and ERK signaling.
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| Duan HX, Li BW, Zhuang X, Wang LT, Cao Q, Tan LH, Qu GF, Xiao S.
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| Am J Physiol Gastrointest Liver Physiol. Jun 1;316(6):G763-G773. doi: 10.1152/ajpgi.00264.2018 2019
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| 4 | SMAD3, TCF21
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| Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.
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| Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T.
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| PLoS Genet. Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct 2018
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| 5 | TCF21
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| Promoter methylation of TCF21 may repress autophagy in the progression of lung cancer.
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| Chen B, Zeng C, Ye Y, Wu D, Mu Z, Liu J, Xie Y, Wu H.
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| J Cell Commun Signal. Jun;12(2):423-432. doi: 10.1007/s12079-017-0418-2. Epub 2017 Oct 30 2018
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| 6 | TCF21
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| Expression of Transcription Factor 21 (TCF21) and Upregulation Its Level Inhibits Invasion and Metastasis in Esophageal Squamous Cell Carcinoma.
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| Chen Y, Zhang C, Chen J, Zhang B, Zhang H, Yang X, Liu J, Wu Q.
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| Med Sci Monit. Jun 17;24:4128-4136. doi: 10.12659/MSM.909138 2018
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| 7 | IL6, TCF21
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| Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells.
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| Akama T, Chun TH.
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| J Biol Chem. Apr 27;293(17):6603-6610. doi: 10.1074/jbc.RA117.000456. Epub 2018 Mar 14 2018
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| 8 | TCF21
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| Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.
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| Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE.
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| J Am Soc Nephrol. Dec;29(12):2795-2808. doi: 10.1681/ASN.2017121278. Epub 2018 Oct 30 2018
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| 9 | TCF21
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| Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer.
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| Dai Y, Duan H, Duan C, Zhou R, He Y, Tu Q, Shen L.
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| Biochem Biophys Res Commun. Jan 15;469(3):430-6. doi: 10.1016/j.bbrc.2015.09.109. Epub 2015 Dec 17. 2016
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| 10 | TCF21
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| Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci.
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| Sazonova O, Zhao Y, Nürnberg S, Miller C, Pjanic M, Castano VG, Kim JB, Salfati EL, Kundaje AB, Bejerano G, Assimes T, Yang X, Quertermous T.
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| PLoS Genet. May 28;11(5):e1005202. doi: 10.1371/journal.pgen.1005202. eCollection 2015 May 2015
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| 11 | TCF21
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| Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS.
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| Maezawa Y, Onay T, Scott RP, Keir LS, Dimke H, Li C, Eremina V, Maezawa Y, Jeansson M, Shan J, Binnie M, Lewin M, Ghosh A, Miner JH, Vainio SJ, Quaggin SE.
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| J Am Soc Nephrol. Nov;25(11):2459-70. doi: 10.1681/ASN.2013121307. Epub 2014 Jun 5 2014
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| 12 | TCF21
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| Tcf21 regulates the specification and maturation of proepicardial cells.
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| Tandon P, Miteva YV, Kuchenbrod LM, Cristea IM, Conlon FL.
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| Development Jun;140(11):2409-21. doi: 10.1242/dev.093385. Epub 2013 May 1 2013
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| 13 | FLT1, TCF21
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| Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.
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| Jin J, Sison K, Li C, Tian R, Wnuk M, Sung HK, Jeansson M, Zhang C, Tucholska M, Jones N, Kerjaschki D, Shibuya M, Fantus IG, Nagy A, Gerber HP, Ferrara N, Pawson T, Quaggin SE.
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| Cell 151(2):384-99. doi: 10.1016/j.cell.2012.08.037. 2012
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| 14 | SRY, TCF21
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| Basic helix-loop-helix transcription factor TCF21 is a downstream target of the male sex determining gene SRY.
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| Bhandari RK, Sadler-Riggleman I, Clement TM, Skinner MK.
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| PLoS One. 6(5):e19935. doi: 10.1371/journal.pone.0019935. Epub 2011 May 17 2011
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| 15 | TCF21
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| Molecular characterization of mesoderm-restricted basic helix-loop-helix protein, POD-1/Capsulin.
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| Miyagishi M, Nakajima T, Fukamizu A.
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| Int J Mol Med 5(1):27-31. 2000
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| 16 | TCF21
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| Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney.
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| Quaggin SE, Vanden Heuvel GB, Igarash P.
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| Mech Dev 71(1-2):37-48. 1998
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