| 1 | EOMES, T, TBX1, TBX15, TBX18, TBX2, TBX3, TBX4, TBX5
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| The Roles of T-Box Genes in Vertebrate Limb Development.
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| Sheeba CJ, Logan MP.
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| Curr Top Dev Biol 122:355-381. doi: 10.1016/bs.ctdb.2016.08.009. Epub 2016 Oct 5.
2017
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| 2 | TBX1, TBX18, TBX2, TBX20, TBX3
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| T-Box Genes in the Kidney and Urinary Tract.
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| Kispert A.
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| Curr Top Dev Biol 122:245-278. doi: 10.1016/bs.ctdb.2016.06.002. Epub 2016 Jul 27.
2017
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| 3 | FGF8, FLRT3, TBX2
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| Tbx2 regulates anterior neural specification by repressing FGF signaling pathway.
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| Cho GS, Park DS, Choi SC, Han JK.
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| Dev Biol. Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020. Epub 2016 Nov 30 2017
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| 4 | OCA2, TBX2
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| The transcription factor TBX2 regulates melanogenesis in melanocytes by repressing Oca2.
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| Chen Y, Pan L, Su Z, Wang J, Li H, Ma X, Liu Y, Lu F, Qu J, Hou L.
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| Mol Cell Biochem 415(1-2):103-9. doi: 10.1007/s11010-016-2680-7. Epub 2016 Mar 12.
2016
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| 5 | GREM1, GREM2, TBX2
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| Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.
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| Farin HF, Lüdtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A.
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| PLoS Genet 9(4):e1003467. doi: 10.1371/journal.pgen.1003467. Epub 2013 Apr 25.
2013
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| 6 | TBX2
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| Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b.
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| Lüdtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A.
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| PLoS Genet 9(1):e1003189. doi: 10.1371/journal.pgen.1003189. Epub 2013 Jan 17.
2013
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| 7 | CNBP, SMARCA5, TBX2, WNT5B
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| Beyond the binding site: in vivo identification of tbx2, smarca5 and wnt5b as molecular targets of CNBP during embryonic development.
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| Armas P, Margarit E, Mouguelar VS, Allende ML, Calcaterra NB.
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| PLoS One 8(5):e63234. doi: 10.1371/journal.pone.0063234. Print 2013.
2013
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| 8 | BMP4, MSX1, TBX2
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| Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development
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| Saadi I, Das P, Zhao M, Raj L, Ruspita I, Xia Y, Papaioannou VE, Bei M
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| Development. Jul;140(13):2697-702. doi: 10.1242/dev.088393. Epub 2013 May 29 2013
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| 9 | PML, TBX2
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| Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.
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| Martin N, Benhamed M, Nacerddine K, Demarque MD, van Lohuizen M, Dejean A, Bischof O.
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| EMBO J 31(1):95-109. doi: 10.1038/emboj.2011.370. Epub 2011 Oct 14.
2012
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| 10 | DEL17Q23, TBX2, TBX4
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| Microdeletion of 17q22q23.2 encompassing TBX2 and TBX4 in a patient with congenital microcephaly, thyroid duct cyst, sensorineural hearing loss, and pulmonary hypertension.
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| Nimmakayalu M, Major H, Sheffield V, Solomon DH, Smith RJ, Patil SR, Shchelochkov OA.
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| Am J Med Genet A 155(2):418-23. doi: 10.1002/ajmg.a.33827. Epub 2011 Jan 13.PMID: 21271665 2011
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| 11 | TBX2
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| Role of Tbx2 in defining the territory of the pronephric nephron.
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| Cho GS, Choi SC, Park EC, Han JK.
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| Development 138(3):465-74.
2011
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| 12 | DEL17Q23, TBX2, TBX4
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| Two new cases with microdeletion of 17q23.2 suggest presence of a candidate gene for sensorineural hearing loss within this region.
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| Schönewolf-Greulich B, Ronan A, Ravn K, Baekgaard P, Lodahl M, Nielsen K, Rendtorff ND, Tranebjaerg L, Brøndum-Nielsen K, Tümer Z.
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| Am J Med Genet A 155(12):2964-9. doi: 10.1002/ajmg.a.34302. Epub 2011 Nov 3.
2011
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| 13 | CDH1, MAGED1, TBX2
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| A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.
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| Kumar S, Park SH, Cieply B, Schupp J, Killiam E, Zhang F, Rimm DL, Frisch SM.
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| Mol Cell Biol 31(19):4036-51. Epub 2011 Jul 11.
2011
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| 14 | DEL17Q23, TBX2, TBX4
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| Identification of a recurrent microdeletion at 17q23.1q23.2 flanked by segmental duplications associated with heart defects and limb abnormalities.
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| Ballif BC, Theisen A, Rosenfeld JA, Traylor RN, Gastier-Foster J, Thrush DL, Astbury C, Bartholomew D, McBride KL, Pyatt RE, Shane K, Smith WE, Banks V, Gallentine WB, Brock P, Rudd MK, Adam MP, Keene JA, Phillips JA 3rd, Pfotenhauer JP, Gowans GC, Stankiewicz P, Bejjani BA, Shaffer LG.
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| Am J Hum Genet 86(3):454-61. Epub 2010 Mar 4.PMID: 20206336 2010
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| 15 | ALMS1, BCAS3, C17orf82, CEP89, DUSP11, FAAP24, GATM, MYH9, NAT8, SHROOM3, SLC22A2, SLC7A9, TBX2, TPRKB, UMOD
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| Genetic loci influencing kidney function and chronic kidney disease.
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| Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J, Luttropp K, Maréchal C, Melander O, Munroe PB, Nordfors L, Parsa A, Peltonen L, Penninx BW, Perucha E, Pouta A, Prokopenko I, Roderick PJ, Ruokonen A, Samani NJ, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen MA, Shuldiner AR, Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg MJ, Swaminathan R, Tanaka T, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI, Jarvelin MR, Mooser V, Abecasis GR, Lightstone L, Scott J, Navis G, Elliott P, Kooner JS.
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| Nat Genet 42(5):373-5. Epub 2010 Apr 11. 2010
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| 16 | DUP17QO, TBX2
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| TBX2 gene duplication associated with complex heart defect and skeletal malformations.
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| Radio FC, Bernardini L, Loddo S, Bottillo I, Novelli A, Mingarelli R, Dallapiccola B.
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| Am J Med Genet A 152A(8):2061-6.PMID: 20635360 2010
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| 17 | NDRG1, TBX2
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| T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells.
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| Redmond KL, Crawford NT, Farmer H, D'Costa ZC, O'Brien GJ, Buckley NE, Kennedy RD, Johnston PG, Harkin DP, Mullan PB.
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| Oncogene 29(22):3252-62. Epub 2010 Mar 29.
2010
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| 18 | PSCA, TBX2
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| Expression of PSCA, PIWIL1, and TBX2 in endometrial adenocarcinoma.
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| Liu WK, Jiang XY, Zhang ZX.
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| Onkologie 33(5):241-5. doi: 10.1159/000305098. Epub 2010 Apr 21.
2010
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| 19 | NDRG2, NDRG4, TBX2
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| Tbx2 misexpression impairs deployment of second heart field derived progenitor cells to the arterial pole of the embryonic heart.
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| Dupays L, Kotecha S, Angst B, Mohun TJ.
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| Dev Biol 333(1):121-31. Epub 2009 Jun 27.PMID: 19563797 2009
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| 20 | TBX2, TBX3
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| Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.
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| Zirzow S, Lüdtke TH, Brons JF, Petry M, Christoffels VM, Kispert A.
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| Dev Biol 336(2):145-55. Epub 2009 Sep 19.PMID: 19769959 2009
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| 21 | HAS2, TBX2
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| T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation.
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| Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T.
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| Proc Natl Acad Sci U S A 106(44):18604-9. doi: 10.1073/pnas.0900635106. Epub 2009 Oct 21.
2009
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| 22 | TBX2
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| Functional characterization of cis-acting elements involved in basal transcription of the human Tbx2 gene: a new insight into the role of Sp1 in transcriptional regulation.
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| Teng H, Parker MI, Prince S.
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| Gene 423(1):8-13. Epub 2008 Jun 21.
2008
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| 23 | TBX2, TBX3
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| Tbx3 represses E-cadherin expression and enhances melanoma invasiveness.
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| Rodriguez M, Aladowicz E, Lanfrancone L, Goding CR.
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| Cancer Res 68(19):7872-81.
2008
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| 24 | TBX19, TBX2, TBX22, TBX3, TBX5
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| T-box genes in human disorders.
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| Packham EA, Brook JD.
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| Hum Mol Genet 12(Suppl 1):R37-44. 2003
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| 25 | TBX2
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| The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
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| Carreira S, Liu B, Goding CR.
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| J Biol Chem 275(29):21920-7. 2000
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| 26 | TBX2
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| Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.
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| Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, van Welsem T, van de Vijver MJ, Koh EY, Daley GQ, van Lohuizen M.
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| Nat Genet 26(3):291-9. 2000
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| 27 | TBX2
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| Genomic structure of TBX2 indicates conservation with distantly related T-box genes.
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| Campbell CE, Casey G, Goodrich K.
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| Mamm Genome 9(1):70-3. 1998
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| 28 | TBX2, TBX5
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| Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development.
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| Gibson-Brown JJ, et al.
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| Development 125(13):2499-509. 1998
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| 29 | TBX2
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| Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family.
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| Law DJ, et al.
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| Mamm Genome 6 : 793-797. 1995
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| 30 | TBX2
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| Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene.
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| Campbell C, et al.
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| Genomics 28 : 255-260. 1995
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| 31 | TBX2
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| An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus.
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| Bollag RJ, et al.
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| Nat Genet 7 : 383-389. 1994
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